Negative / Null Result ReportOpen accessOrthopedic surgery
Ahmet Salduz, Fatih Dikici, Önder Ismet Kılıçoğlu et al. · 2017 · Journal of Orthopaedic Surgery
Purpose: The aim of our study is to investigate the bone ongrowth of two different alternative surfaces and the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on osseointegration. Methods: Hips of 40 New Zealand white rabbits were operated bilaterally. Hydroxyapatite (HA)-coated titanium rods were implanted into the right femur, and grit-blasted titanium rods were implanted into the left femur. They were divided into three groups. At the end of 8 weeks, both femora of the rabbits were removed and investigated biomechanically and histologically. Results: HA-coated implants had a signif
View details →DOI: 10.1177/2309499016684410 Negative / Null Result ReportOpen accessMedicine
XUE Bing, XI Hualei, YAO Lihong, XU Wanqiu, XU Xiaohang, LIN Song, PIAO Guiyan, WANG Xiumei · 2025 · 口腔疾病防治
Objective To investigate the effect of neurite outgrowth inhibitor extracellular peptide residues 1-40 (NEP1-40) combined with poly (lactic-co-glycolic acid) (PLGA) and gelatin electrospun fiber membrane on facial nerve repair in rats. Methods According to the principle of random grouping, 108 male SD rats were divided into four groups ( n = 27 in each group, approved by the ethics committee), namely, the sham group, control group, PLGA group, and NEP1-40 + PLGA group. A facial nerve fracture model was established for all of the groups except for the sham group. The control group received no f
View details →DOI: 10.12016/j.issn.2096-1456.202440237 Negative / Null Result ReportOpen accessEcology
Mnqobi Mamba, Nicolas J. Fasel, Themb'alilahlwa A.M. Mahlaba et al. · 2019 · Global Ecology and Conservation
Conversion of native habitats into agricultural monocultures is a major cause of biodiversity loss favouring a small number of generalist species. Rodents can cause significant declines in crop yield, hence understanding the factors affecting their population dynamics is of importance to the agricultural sector. Sugarcane plantations in African savannas harbour a low diversity of small mammals, with a single genus (Mastomys spp.) often dominating the community. Our study investigated the factors that shape the composition of the small mammal community and the life-history traits of the dominan
View details →DOI: 10.1016/j.gecco.2019.e00752 Negative / Null Result ReportOpen accessAnesthesiology
Hasanul Arifin, Heru Kurniawan · 2016 · Jurnal Anestesi Perioperatif
Serum creatinine has many limitations when being used to diagnose acute kidney injury (AKI), especially in the scope of intensive care unit due to its low sensitivity to depict the kidney dysfunctional level of critically-ill patients. Out of numerous new available biological markers, four biological markers are widely used all over the world to detect AKI, e.g. neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, KIM-1, and interleukin-18. The purpose of this study was to determine the sensitivity and specificity of serum cystatin C and creatinine in establishing the diagnosis of ac
View details →DOI: 10.15851/jap.v4n2.819 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Xiaotong Xu, Jinglan Jin, Yuwei Liu et al. · 2023 · BMC Gastroenterology
Abstract Background and aims To investigate the usefulness of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), protein C (PC), and thromboelastography (TEG) to serve as a predictor of portal vein thrombosis (PVT) in patients with liver cirrhosis. Additionally, we examined the clinical significance of the above indicators in terms of disease progression. Methods A total of 123 patients with liver cirrhosis were recruited from May 2021 to December 2021, according to the imaging findings. They were divided into the PVT group (n = 52) and the non-PVT group (n = 71). Furthermore, patients
View details →DOI: 10.1186/s12876-022-02632-z Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Dong-Yun Kim, Eonju Park, Chan Yeong Heo et al. · 2021 · Breast
Purpose: This study investigated whether hypofractionated adjuvant radiotherapy (RT) increased breast-related complication(s) compared to conventional fractionated RT in reconstructed breast cancer patients. Methods: We conducted a retrospective review including 349 breast cancer patients who underwent immediate breast reconstruction following mastectomy or breast-conserving surgery (BCS) between 2009 and 2018 at two institutions. All patients were treated with adjuvant RT via either a conventional fractionated or hypofractionated regimen. We defined a major breast complication as a breast-rel
View details →DOI: 10.1016/j.breast.2020.11.020 Negative / Null Result ReportOpen accessMedicine
Fatemeh Samiei Siboni, Zainab Alimoradi, Tahereh Sadegi · 2013 · مجله دانشگاه علوم پزشکی بیرجند
Background and Aim: Life style can cause stress and anxiety and consequently, hypertension. Regarding nurses' influencial role in implementing educational programs to increase patients’ self-control, the present research was designed to study the impact of a lifestyle promoting educational programs on controlling stress, anxiety, depression, and hypertewnsion in Qazvin Mino area in 2010. Materials and Methods: after the present study was a pre/post semi-experimental one conducted on 55 hypertensives. Living in Qazvin Minodar region. DAS (Depression, Anxiety, Stress)-21 general questionnaire an
Negative / Null Result ReportOpen accessMedicine (General)
Zhui-Feng Guo, Fan Yang, Xu-Wei Lu et al. · 2021 · Journal of International Medical Research
Objective To explore the significance of the prostate central gland to total gland volume ratio (PVc/PV) in the diagnosis of prostate cancer (PCa) in patients with prostate specific antigen (PSA) levels in the grey zone (4–10 ng/ml). Methods This retrospective study enrolled patients that had undergone prostate biopsy. The volume of the prostate and the central prostate gland were measured. The differences in PSA, the ratio of free to total PSA (f/tPSA), PSA density (PSAD) and PVc/PV between the PCa and non-PCa groups were compared. Receiver operating characteristic curve analysis for PCa and
View details →DOI: 10.1177/03000605211019879 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Mohamed Abdelkhalek, Ahmed Setit, Francesco Bianco et al. · 2018 · Annals of Coloproctology
Purpose Revolutions have occurred over the last 3 decades in the management of patients with colorectal cancer. Most advances were in rectal cancer surgery, especially after the introduction of the total mesorectal excision (TME) by Heald. However, no parallel advances regarding colon cancer surgeries have occurred. In 2009, Hohenberger introduced a new concept trying to translate the survival advantages of TME to patients with colon cancer. This relatively new concept of a complete mesocolic excision (CME) with central vascular ligation (CVL) in the management of patients with colon cancer re
View details →DOI: 10.3393/ac.2017.08.05 Negative / Null Result ReportOpen accessAnimal culture
RAVIKANTH JETTY, S SREEDHAR, CH VENKATA SESHAIAH2 et al. · 2025 · Indian Journal of Animal Sciences
The present research was conducted to study the effect of fan and foggers on Temperature Humidity Index (THI) and physiological responses in Nellore brown sheep during summer. Twenty ewes of age 3-5 years from sheep unit of Livestock Farm Complex of NTR college of Veterinary Sciences, Gannavaram were divided into 2 groups of each 10 ewes each in a completely randomized design on the basis of body weight. The animals in the group-I were considered as control whereas the animals in the group-II were equipped with fan and foggers for modification of microclimate in the shed. Data on temperature-h
View details →DOI: 10.56093/ijans.v95i3.146026 Negative / Null Result ReportOpen accessScience (General)
Chong Teng, Ling Li, Dan Su et al. · 2024 · Heliyon
Objective: To detect levofloxacin (LFX) and moxifloxacin (MFX) resistance among rifampicin-resistant tuberculosis (RR-TB) isolates, and predict the resistance level based on specific mutations in gyrA and gyrB genes. Methods: A total of 686 RR-TB isolates were collected from Chinese Drug Resistance Surveillance Program from 2013 to 2020. The minimum inhibitory concentrations (MICs) of 12 anti-TB drugs were acquired using the broth microdilution method, followed by whole genome sequencing (WGS) analysis. Results: Among the 686 RR isolates, the most prevalent resistance was to isoniazid (80.5 %)
View details →DOI: 10.1016/j.heliyon.2024.e31959 Negative / Null Result ReportOpen accessManagement. Industrial management
Majid Aligholizadeh, Mohammad Akbari, Fatemeh Zandian et al. · 2014 · مطالعات مدیریت راهبردی
The aim of Paper is to analyze and evaluate the performance of management in Tehran academic public libraries based on the model of EFQM that tries to identify the weak points and strong points of the management, plan for the improvement of strong points and resolve the weak points to get to a more competent and desirable situation in the society so that they can be able to improve their services and satisfy the needs of their members and customers more than ever. The methodology used to conduct this research is a survey and to collect the data a 72 item questionnaire of European Foundation fo
Negative / Null Result ReportOpen accessDentistry
Nsar Muhyaddin Aziz · 2022 · Erbil Dental Journal
Background and objectives: Gutta percha solvents like chloroform and orange oil have different effects on physio-chemical properties like the microhardness of root dentine. Aim: Effects of sesame oil on the micro hardness of root dentin after using chloroform and orange oil as guttapercha solvents. Methods: Twenty three extracted single rooted both upper and lower premolars were used crown separated from the root from the cement enamel junction ,remaining roots longitudinally sectioned from buccolingual direction each piece of roots mounted in cold cure acrylic resin and dentin surface of the
Negative / Null Result ReportOpen accessMedicine (General)
Dalia M. Kamel, Nashwa S. Hamed, Neveen A. Abdel Raoof et al. · 2017 · Journal of Advanced Research
The aim of this study was to compare the effects of pulsed electromagnetic field versus pulsed ultrasound in treating patients with postnatal carpal tunnel syndrome. The study was a randomized, double-blinded trial. Forty postnatal female patients with idiopathic carpal tunnel syndrome were divided randomly into two equal groups. One group received pulsed electromagnetic field, with nerve and tendon gliding exercises for the wrist, three times per week for four weeks. The other group received pulsed ultrasound and the same wrist exercises. Pain level, sensory and motor distal latencies and con
View details →DOI: 10.1016/j.jare.2016.11.001 Failed Experiment ReportOpen accessDermatology
Stefan J. Jodl, Margitta Worm, Frauke Friedrichs et al. · 2025 · Dermatology and Therapy
Abstract Introduction Interleukin-1 receptor-associated kinase 4 (IRAK4) is expressed in various immune cells and regulates proinflammatory cytokine production. Its inhibition represents a novel, promising therapeutic option in the treatment of atopic dermatitis (AD). Zabedosertib (BAY1834845) is a potent, selective IRAK4 inhibitor that suppresses markers of local and systemic immune responses. This study aimed to evaluate the efficacy and safety of zabedosertib in adults with moderate-to-severe AD. Methods DAMASK was a randomized, double-blind, 12-week, placebo-controlled, phase 2a, proof-of-
View details →DOI: 10.1007/s13555-025-01505-z Failed Experiment ReportOpen accessTherapeutics. Pharmacology
Girish Parthan, Shobhit Bhansali, Anura V. Kurpad et al. · 2018 · BMC Pharmacology and Toxicology
Abstract Background Dipeptidyl peptidase 4 (DPP4) inhibitors improve glycemic control by promoting GLP1-mediated glucose-dependent insulin secretion and suppression of glucagon. Sitagliptin and vildagliptin have been shown to improve insulin sensitivity in patients with type 2 diabetes mellitus (T2DM). However, these patients had uncontrolled blood glucose at inclusion; therefore, the improvement in insulin sensitivity observed in these studies could be attributed to the drug per se and/or reduction in glucotoxicity. This study examines the effect of linagliptin on insulin sensitivity and β-ce
View details →DOI: 10.1186/s40360-018-0228-z Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Christine Annaheim, Kerstin Hug, Caroline Stumm et al. · 2022 · Frontiers in Human Neuroscience
BackgroundFrontal brain dysfunction is a major challenge in neurorehabilitation. Neurofeedback (NF), as an EEG-based brain training method, is currently applied in a wide spectrum of mental health conditions, including traumatic brain injury.ObjectiveThis study aimed to explore the capacity of Infra-Low Frequency Neurofeedback (ILF-NF) to promote the recovery of brain function in patients with frontal brain injury.Materials and methodsTwenty patients hospitalized at a neurorehabilitation clinic in Switzerland with recently acquired, frontal and optionally other brain lesions were randomized to
View details →DOI: 10.3389/fnhum.2022.979723 Negative / Null Result ReportOpen accessEngineering (General). Civil engineering (General)
Weichuan Zhang, Mingxian Zhao, Zhongyan Yang et al. · 2024 · Developments in the Built Environment
A significant amount of waste is generated during the sandstone mining process. This study explores the use of red sandstone waste as a supplementary cementitious material to address environmental concerns in cement production. The experimental methods include isothermal calorimetry, compressive strength testing, thermogravimetric analysis, X-ray diffraction, infrared spectroscopy, scanning electron microscopy, high-temperature damage testing (200, 600, and 900 °C), and mesoscopic image analysis. The experimental findings reveal the following: (1) Red sandstone powder enhanced cement hydration
View details →DOI: 10.1016/j.dibe.2024.100346 Failed Experiment ReportOpen accessMedicine
Almira Ada Diken Türksayar, Simge Baytur · 2023 · Sabiad
Objective: The aim of this in vitro study was to compare the biaxial flexural strengths of permanent restorative materials produced by additive manufacturing and milling after thermal aging. Material and methods: For this study, three study groups were formed by producing disc-shaped specimens with a 3D printer (Form3, Formlabs) using permanent crown material (Permanent Crown, Somerville, MA) and two different resin-containing materials (Brilliant Crios,Coltene/ Whaledent; Cerasmart, GC Europe) by the milling method (n=10). The entire production process was carried out in accordance with the m
View details →DOI: 10.26650/jarhs2023-1200694 Negative / Null Result Report
D O Geavlete, C Beladan, D Deleanu et al. · 2019 · European Heart Journal
Abstract Introduction Different consequences concerning the cardiac function and structure in patients with renal artery stenosis (RAS) and completely different patterns of activation of the renin-angiotensin-aldosteron system were…
View details →DOI: 10.1093/eurheartj/ehz745.0431 Negative / Null Result ReportOpen accessEducation (General)
Vincent Reynaert, Vincent Reynaert, Jalal Possik et al. · 2024 · Frontiers in Education
IntroductionThe field of poetry learning is currently facing significant challenges, primarily due to a lack of motivation and interest among students. This has resulted in educators encountering difficulties in identifying suitable educational alternatives. To address the latter issue, immersive learning has emerged as a potential solution, as it has been demonstrated to enhance motivation and learning outcomes in a multitude of fields.MethodsIn light of the aforementioned considerations, this field study seeks to examine the potential of virtual reality (VR) tools in enhancing the memorizati
View details →DOI: 10.3389/feduc.2024.1463635 Negative / Null Result ReportOpen accessDentistry
AHMAD ZAAZA, Nevien Mohamed, Gaffar El Halawani · 2025 · Alexandria Dental Journal
Introduction: Osseo-integrated dental implants were traditionally load-free for up to six months while they healed. Patients usually feel dissatisfied with the long loading times. Several studies have been conducted to improve osseointegration, decrease loading time, and increase patient satisfaction.Objectives: This study aimed to evaluate and compare both clinically and radiographically the effect of hyaluronic acid (HA) versus Titanium-Platelet Rich Fibrin (T-PRF) in enhancing osseointegration around anterior maxillary dental implants. Materials and Methods: Twelve patients with extracted m
View details →DOI: 10.21608/adjalexu.2024.282413.1497 Negative / Null Result ReportOpen accessMedicine
Elif Özdemir, Şeyda Türkölmez · 2020 · Ankara Medical Journal
INTRODUCTION: This study aims to disclose the frequency and clinical significance of incidental prostatic uptake during FDG PET imaging. METHODS: FDG PET images of 1839 male patients undergoing imaging for non-prostate and non-urinary bladder malignancy indications were retrospectively reviewed for the presence of incidental prostatic FDG uptake. Prostatic volume, calcification and the presence and pattern of FDG uptake were evaluated. Further follow-up prostatic evaluation results were comparatively assessed. RESULTS: Incidental prostatic FDG uptake was detected in 41 out of 1839 patients(2.2
View details →DOI: 10.5505/amj.2020.93653 Negative / Null Result ReportOpen accessMaterials of engineering and construction. Mechanics of materials
DUAN Peng, LIU Zong-de, TAO Xiang-qian, GU Shu-chao · 2021 · Cailiao Baohu
At present, the changes of microstructure and mechanical properties of T23 steel after served for more than 50 000 h have been less studied.In this work, with using the heat-delivery surface tubes of a 600 MW super-critical boiler as research object, the T23 steel final reheater tubes at various positions after about 80 000 h of service time were tested by microstructure analysis, tensile properties tests at room temperature and 525 ℃ temperature, and the deterioration degree and difference in mechanical properties between back and meet smoke side of tubes after long-term service were investig
View details →DOI: 10.16577/j.cnki.42-1215/tb.2021.01.008 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Eric V. Li, Sai K. Kumar, Jonathan A. Aguiar et al. · 2024 · BJUI Compass
Abstract Objective This study aimed to evaluate the association of dynamic contrast enhancement (DCE) with clinically significant prostate cancer (csPCa, Gleason Grade Group ≥2) and compare biparametric magnetic resonance imaging (bpMRI) and multiparametric MRI (mpMRI) nomograms. Subjects/patients and methods We identified a retrospective cohort of biopsy naïve patients who underwent pre‐biopsy MRI separated by individual MRI series from 2018 to 2022. csPCa detection rates were calculated for patients with peripheral zone (PZ) lesions scored 3–5 on diffusion weighted imaging (DWI) with availab
View details →DOI: 10.1002/bco2.415 Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Takuji Yokoe, Takuya Tajima, Shuichi Kawagoe et al. · 2022 · BMC Musculoskeletal Disorders
Abstract Background A number of studies have evaluated risk factors for lateral ankle sprain (LAS) or chronic lateral ankle instability (CLAI). However, the definitive risk factors for LAS or CLAI remain controversial. The purpose of this study was to evaluate whether the contralateral healthy ankles of subjects with ipsilateral mechanical lateral ankle laxity (group I) show greater lateral ankle laxity in comparison to the healthy ankles of bilateral healthy controls (group B). Methods From March 2020, anterior talofibular ligament (ATFL) lengths of young adult volunteers were cross-sectional
View details →DOI: 10.1186/s12891-022-05838-0 Negative / Null Result ReportOpen accessAnesthesiology
Mahmoodzadeh Hossein, Movafegh Ali, Beigi Noshin · 2009 · Saudi Journal of Anaesthesia
Background: Dextromethorphan, the D-isomer of the codeine analog levorphanol, is a weak, noncompetitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. It has been suggested that NMDA receptor antagonists induce preemptive analgesia when administered before tissue injury occurs, thus decreasing the subsequent sensation of pain. Materials and Methods: The study was conducted in the Dr. Ali Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran, between February 2005 and December 2006. In this study, 72 patients scheduled for elective cholesyctectomy were randomized into three g
Negative / Null Result ReportOpen accessFood processing and manufacture
YAN Rui, TANG Min, CHEN Dongfang, HUANG Shirong, MEI Xin · 2023 · Shipin Kexue
The feasibility of using white radish powder as a nitrite substitute in dry fermented pork sausages was evaluated. Four groups of sausage were prepared by using a multi-strain starter culture (VBM-60, Sacco): negative control (NC, without nitrate or nitrite), positive control (PC, with 150 mg/kg sodium nitrite), 0.5% white radish powder (R0.5), and 1% white radish powder (R1). The effects of nitrite substitution by white radish powder on the physicochemical, microbiological and sensory characteristics of dry fermented sausage during production and storage were investigated. The results showed
View details →DOI: 10.7506/spkx1002-6630-20220713-138 Negative / Null Result ReportOpen accessOrthopedic surgery
Jinli Guo, Chaona Gao, Haifeng Xin et al. · 2019 · Journal of Orthopaedic Surgery and Research
Abstract Purposes Hip fracture leads to decreased activity and an increased risk of pulmonary complications. The main purpose of this study was to observe the lung capacity, cough capacity of the elderly patient with acute hip fracture, and assess the effects and the feasibility of using a special-designed “upper-body yoga” training to treat elderly patients with hip fracture. Methods This was a prospective, randomized, and single-blind study. Eighty-four subjects aged over 65 years were randomly divided into either a control group or a yoga group to undergo an abdominal breathing program or a
View details →DOI: 10.1186/s13018-019-1295-6 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Jing Zhang, Chengcheng Shao, Jiajia Zhu et al. · 2025 · Frontiers in Cardiovascular Medicine
BackgroundThis study investigated the clinical characteristics of in-hospital cardiac arrest (IHCA) in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock and assessed the related in-hospital and post-discharge mortality.MethodsThis study included 148 patients with AMI complicated by cardiogenic shock who were admitted to the Cardiac Critical Care Center, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University between September 1, 2021 and July 31, 2024. Study participants were divided into two groups according to the occurrence of IHCA (IHCA
View details →DOI: 10.3389/fcvm.2025.1663933 