A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21339 results · page 525 of 712
Kusztor A, Mulay N, Yamada M et al. · 2025 · Neuroscience of consciousness
During an acute episode of depersonalization/derealization (DP/DR), people report a complex and idiosyncratic change in their perceptual experience. Specifically, derealisation describes the experience of detachment from the external world…
Raut U · 2023 · Preprint
The formation of mini black holes is now considered to be an inescapable consequence of TeV scale particle collision scenarios in extra-dimensional/ADD models. Furthermore, such mini black holes have been predicted to be produced at…
Beaver JN, Nicodemus MM, Spalding IR et al. · 2025 · eNeuro
Mice offer a wealth of opportunities for investigating brain circuits regulating multiple behaviors, largely due to their genetic tractability. Social behaviors are translationally relevant, considering both mice and humans are highly…
Kraft VM, Jones DR, Smyth JM et al. · 2026 · Emotion (Washington, D.C.)
Variability in daily emotional experiences may be important for both mental and physical health and may be influenced by individual differences such as age, gender, race, and ethnicity. Research on individual differences in affect…
Coppeto DJ, Martin JS, Ringen EJ et al. · 2024 · Peptides
The neurohormones oxytocin (OT) and arginine vasopressin (AVP) are involved in social behaviors and psychiatric conditions. However, more research on nonhuman primates with complex social behaviors is needed. We studied two closely-related…
Shapouri S, Rafiee Y · 2024 · Human nature (Hawthorne, N.Y.)
Considering the role of human interactions in infectious disease outbreaks and cooperation in mitigating natural disasters consequences, ecological threats to human survival have been among proposed drivers of collectivism. Utilizing…
Sarfraz S, Fouad Elganainy M, Waris U et al. · 2026 · Proceedings (Baylor University. Medical Center)
Background Secondhand smoke (SHS) is a major cardiovascular risk factor, but its relationship with resting tachycardia, a marker of autonomic imbalance and adverse prognosis, remains unclear in young adults. Methods We analyzed adults aged…
Roozenbeek J, Lasser J, Marks M et al. · 2025 · Royal Society open science
The spread of misinformation on social media continues to pose challenges. While prior research has shown some success in reducing susceptibility to misinformation at scale, how individual-level interventions impact the quality of content…
Wei Y, Li J · 2025 · Discover oncology
Background Non-alcoholic fatty liver disease (NAFLD) has been increasingly associated with hepatocellular carcinoma (HCC) risk in observational studies, yet the causal nature of this relationship and its impact on systemic lipid metabolism…
Zhou C, Dong X, Chen G et al. · 2025 · Nature medicine
After the global approval of atezolizumab plus bevacizumab and chemotherapy as first-line metastatic nonsquamous non-small-cell lung cancer (nsqNSCLC) treatment, the IMpower151 ( NCT04194203 ) trial was conducted in China to address…
Esparragosa Vazquez I, Sanson M, Chinot OL et al. · 2024 · Neuro-oncology advances
Background Based on preclinical studies showing that IDH-mutant (IDHm) gliomas could be vulnerable to PARP inhibition we launched a multicenter phase 2 study to test the efficacy of olaparib monotherapy in this population. Methods Adults…
Reynolds GP · 2024 · Journal of psychopharmacology (Oxford, England)
A major effort of the pharmaceutical industry has been to identify and market drug treatments that are effective in ameliorating the symptoms of psychotic illness but without the limitations of the current treatments acting at dopamine D2…
Takahara N, Nakai Y, Isayama H et al. · 2022 · Preprint
Purpose: Given the promising activity and tolerability of FOLFIRINOX as a second-line treatment for advanced biliary tract cancer (BTC), it can be an attractive first-line treatment option as well. Materials: and Methods: This is a…
Zumla A, Rosenthal PJ, Sam-Agudu NA et al. · 2025 · The American journal of tropical medicine and hygiene
On August 14, 2024, following a regional declaration by the Africa Centres for Disease Control and Prevention, the World Health Organization declared mpox a Public Health Emergency of International Concern, marking the second such…
Yuan H, Curran JG, Keith SW et al. · 2021 · Headache
Objective To evaluate the efficacy and safety of intravenous (IV) Ibuprofen for acute treatment of migraine. Background IV nonsteroidal anti-inflammatory drugs (NSAIDs) are an alternative to oral NSAIDs, especially in patients with severe…
Singer JM, Wing JJ, Klein EG et al. · 2026 · Journal of public health policy
In the United States certain groups, such as African Americans (AA) and sexual minorities (SM) have disproportionately high rates of flavored tobacco use. Policies restricting flavored tobacco may especially benefit these groups and lead…
Dragan KL · 2026 · Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management]
Low-income housing is often of substandard quality. Health care payers like Medicaid and Medicare are piloting reimbursement for housing quality improvement with the rationale of reducing expenses from acute care use, but little is known…
Zevallos-Morales A, Romani-Huacani E, Psoter KJ et al. · 2025 · Frontiers in public health
Background Peru has one of the highest burdens of asthma in the world, as well as large gaps in access to evidence-based treatments. Studies often overlook the ways in which the research context and data collection activities interact and…
Jónsdóttir LK, Forslund T, Frick MA et al. · 2024 · Developmental science
Previous research and theory indicate an importance of the quality of the early caregiving environment in the development of self-regulation. However, it is unclear how attachment security and maternal sensitivity, two related but distinct…
Bhardwaj A, Musci RJ, Blackwell A et al. · 2025 · International health trends and perspectives
Objective Existing research points to how increasing male engagement in public health interventions without addressing gender inequities can perpetuate power imbalances in a relationship which may lead to increased stress and anxiety for…
He Y, Huang B, Chen J et al. · 2025 · European journal of medical research
Background Anemia is associated with worse stroke outcomes, but prior studies seldom focus on patients with spontaneous supratentorial intracerebral hemorrhage (ICH) treated in township-level primary hospitals. Methods We performed a…
Li R, Briers T, McDonald S · 2023 · Preprint
Understanding the cross-cultural differences in emotion perception has captured the interest of researchers for decades. While various mechanisms have emerged to explain such differences, the general inclination to differentiate emotions,…
Schauer G, Grassi PR, Gharabaghi A et al. · 2023 · Preprint
The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential TMS studies have revealed differences in conscious perception following parietal stimulation, fuelling the notion…
Lee AJ, Jones BC, Zietsch BP et al. · 2023 · Scientific reports
Although many researchers have proposed that women will show stronger preferences for male facial masculinity when conception probability is high, empirical tests of this hypothesis have produced mixed results. One possible explanation for…
Kardouh MS, Van Wagoner C, Coleman J et al. · 2026 · Cureus
Objectives Whiplash injuries are among the most common cervical spine injuries in the pediatric population. Limited literature demonstrates a potential link between cervical spine trauma and demyelinating disease, such as multiple…
Liu J, Long Y, Yang Z · 2026 · Nutrients
Background Growing evidence suggests that vitamin D plays a role in the pathophysiology of childhood asthma. However, its effectiveness in reducing asthma exacerbations and improving asthma-related outcomes remains controversial. Methods…
Møller P, Roursgaard M · 2024 · Mutation research. Reviews in mutation research
Humans ingest particles and fibers on daily basis. Non-digestible carbohydrates are beneficial to health and food additives are considered safe. However, titanium dioxide (E171) has been banned in the European Union because the European…
Jin Q, Liu Y, Tong Q et al. · 2025 · Frontiers in nutrition
Objective To examine whether a concise, clinic-feasible Patient Inflammatory Diet Score (PIDS) relates to prevalent pancreatic cancer and cardiovascular disease (CVD) in a hospital population, and to explore associations with systemic…
Davidenko N, Day J · 2025 · Memory & cognition
Humans' ability to draw faces accurately from memory is extremely rare. One source of difficulty is the drawing process itself, which requires converting a complex, three-dimensional mental representation to a two-dimensional drawing. To…
Gaskins AJ, Newman AJ, Kawwass JF et al. · 2026 · Environmental research
Background While extreme ambient heat has been associated with several adverse pregnancy and birth outcomes little is known regarding the link between extreme ambient temperatures and human fertility. Objective To evaluate the associations…