Negative / Null Result ReportMedicine
Ekinci EI, Maldonado SG, Unseld A et al. · 2026 · Diabetes, obesity & metabolism
Aims This post hoc analysis evaluated the effect of survodutide on beta-cell function, insulin sensitivity, and glucose biomarkers in two phase 2 trial populations. Materials and methods Trial 1404-0002 randomised 413 participants with…
View details →DOI: 10.1111/dom.70861 Negative / Null Result ReportMedicine
Pyasik M, Marini E, Ippolito G et al. · 2026 · Acta psychologica
In a predictive processing framework, religiosity and spirituality (R&S) have been linked to increased reliance on prior knowledge and decreased prediction error monitoring. In addition, R&S might be differentially related to processing…
View details →DOI: 10.1016/j.actpsy.2026.107185 Negative / Null Result ReportMedicine
Piri K, Gholamzadeh Jofreh M, Haghighizadeh MH et al. · 2026 · BMC psychology
Introduction Fear of childbirth (FOC) is a significant factor contributing to requests for elective cesarean sections. This study aimed to compare the effectiveness of internet-based cognitive behavioral therapy (ICBT) versus in-person…
View details →DOI: 10.1186/s40359-026-04903-w Negative / Null Result ReportMedicine
Dijksterhuis J, Hurmuz MZM, van Dartel D et al. · 2026 · European geriatric medicine
Purpose Older hip fracture patients are often frail, complicating their recovery trajectories. Insight into patients' resilience may help in getting more understanding of their predicted recovery and adjusting their treatment plan…
View details →DOI: 10.1007/s41999-026-01514-x Negative / Null Result ReportOpen accessMedicine
Shanmugasundaram D, Wang RA · 2026 · Journal of toxicology
Objective Zylaria comprises a blend of botanical components, including Xylaria Nigripes (mycelium), Cuscuta Chinensis (seed) and Panax Notoginseng (root). This study aimed to evaluate the potential toxicity of Zylaria when administered…
View details →DOI: 10.1155/jt/6989296 Negative / Null Result ReportOpen accessMedicine
Motomura T, Higashi M, Hattori A et al. · 2026 · Internal medicine (Tokyo, Japan)
Objective Hyperuricemia is associated with cardiovascular disease and chronic kidney disease (CKD). Dotinurad is a new uricosuric drug that has not been evaluated in clinical trials in patients with advanced CKD (CKD G3b-G5). This study…
View details →DOI: 10.2169/internalmedicine.5834-25 Negative / Null Result ReportMedicine
Pedersen TA, Mori Y, Botteri E et al. · 2026 · Endoscopy
Background The effect of computer-aided detection (CADe) on performance of endoscopists with different experience levels is not well understood. This study assessed whether CADe use promotes learning or deskilling. Methods We performed a…
View details →DOI: 10.1055/a-2858-7084 Negative / Null Result ReportMedicine
Hoskens S, Bamps K, Herteleer M · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Objectives The percutaneous placement of iliosacral (IS) and transsacral (TS) screws has become a standard practice for the treatment of pelvic fractures. Due to the complex sacral anatomy, accurate screw placement is essential to avoid…
View details →DOI: 10.1007/s00590-026-04768-0 Negative / Null Result Report
Sacconi R, Saladino S, Forte P et al. · 2026 · Preprint
Abstract There is a lack of knowledge about the effect of smoking activity on the anatomy and functionality of retinal vessels. The aim of this low-risk, single-center, case-control, interventional clinical trial (ClinicalTrials.gov ID…
View details →DOI: 10.21203/rs.3.rs-8916335/v1 Negative / Null Result Report
Cagini C, Messina M, Fiore T et al. · 2026 · Preprint
Abstract Purpose This study investigates the efficacy of a liposomal ophthalmic solution containing cross-linked hyaluronic acid, trehalose, and stearylamine in reducing the occurrence of dry eye-like signs and symptoms in patients…
View details →DOI: 10.21203/rs.3.rs-9533021/v1 Negative / Null Result Report
Saud MA, Khamees Abed S, Shahooth MA et al. · 2026 · Preprint
Background: While ivermectin is a common antiparasitic drug used in veterinary medicine, the effects of repeated administration at therapeutic doses have not been well studied. Of particular interest is the impact of ivermectin on…
View details →DOI: 10.12688/f1000research.174211.2 Negative / Null Result Report
Moreira-Vera D, Solórzano MLP, Marín-Pérez AL · 2026 · Preprint
Abstract Introduction: Ethical decision-making is a core competency in medical training. However, evidence regarding moral reasoning and ethical sensitivity among medical students in Latin America remains limited, particularly in settings…
View details →DOI: 10.21203/rs.3.rs-9520858/v1 Negative / Null Result ReportMedicine
Hamsika V, Batra P, Bhaskar V et al. · 2026 · Pediatric emergency care
Objective To compare IVC/Ao ratio, IVC collapsibility/distensibility indices before and after the administration of fluid bolus therapy in children with non-hemorrhagic shock using point of care ultrasound, and to correlate the changes in…
View details →DOI: 10.1097/pec.0000000000003626 Negative / Null Result Report
Ali ET, Findlay BL · 2026 · Preprint
Sustainable agriculture has driven increased exploration of microbial inoculants as a promising strategy to boost plant growth for higher yield and enhance secondary metabolism to increase crop nutritional value. However, their influence…
View details →DOI: 10.64898/2026.06.02.729675 Negative / Null Result Report
Wang W, Chen Z, Li M et al. · 2026 · Preprint
Fundus fluorescein angiography (FFA) is the gold standard for assessing diabetic retinopathy (DR) severity, but whether different contrast diffusion times affect staging remains unclear. Following two clinical DR staging criteria, we…
View details →DOI: 10.20944/preprints202606.0206.v1 Negative / Null Result ReportOpen accessMedicine
Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research
Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…
View details →DOI: 10.4258/hir.2026.32.1.14 Negative / Null Result ReportMedicine
Marani N, di Gennaro D, Garotti R et al. · 2026 · Frontiers in psychiatry
Introduction Sensory processing abnormalities represent a high-impact clinical feature in individuals with Autism Spectrum Disorder (ASD). Sensory alterations can be classified by modality and behavioral responses to stimuli. The…
View details →DOI: 10.3389/fpsyt.2026.1771832 Negative / Null Result ReportMedicine
Ansari D, Bethel JA, Greeneway GP et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)
Background and objectives Lateral interbody fusion represents a minimally-invasive approach to achieve indirect decompression via disc height restoration and alignment correction in patients with degenerative lumbar spondylolisthesis. If…
View details →DOI: 10.1227/ons.0000000000002019 Negative / Null Result ReportMedicine
White RL, Read QD, Valles SM · 2026 · Journal of invertebrate pathology
Solenopsis invicta virus 3 (SINV3) is a biological control agent against the red imported fire ant, S. invicta. We attempted to improve the virus' effectiveness with organosilicone adjuvants hydroxy trisiloxane [hydroxyTSX] and methoxy…
View details →DOI: 10.1016/j.jip.2026.108573 Negative / Null Result ReportMedicine
Rasmussen PL, Rinnan Å, Nielsen SB et al. · 2026 · Food Hydrocolloids.
The utilization of bovine casein for creating casein micelles with properties resembling those in human milk presents an opportunity to bridge the nutritional gap between human milk and infant formula. However, the processing of these…
Negative / Null Result ReportMedicine
Williams AJ, Pum JM, Deyoung JK et al. · 2026 · The journal of hand surgery Asian-Pacific volume
Background: The purpose of this study was to compare Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (UE) and PROMIS Pain Interference (PI) scores before and after carpal tunnel release (CTR) between…
View details →DOI: 10.1142/s2424835526500189 Failed Experiment Report
Doumbia M, Yoroba F, Koné B et al. · 2026 · Preprint
Abstract This study evaluates how different physical parameterization schemes affect precipitation simulation in the Bandama watershed (Côte d’Ivoire) using the RegCM5 regional climate model. Thirteen configurations were developed,…
View details →DOI: 10.21203/rs.3.rs-9997831/v1 Abandoned HypothesisMedicine
Smurzynska Z, Lerolland E, Siedlecki KL · 2026 · Memory (Hove, England)
Previous research examining the directive function in autobiographical memory in college-aged participants found that recalling autobiographical memories related to physical activity was associated with an increase in subsequent physical…
View details →DOI: 10.1080/09658211.2026.2680911 Negative / Null Result Report
HOUNGNIBO S, KOUAGOU R, De SOUZA A et al. · 2026 · Preprint
Abstract Strategic allocation of conditional incentives aiming at promoting female school attendance within West African Francophone countries can yield substantial household-level welfare gains in many subregions, specifically in Benin…
View details →DOI: 10.21203/rs.3.rs-10133666/v1 Negative / Null Result ReportMedicine
Fritsch C, Grosdidier M, Gégout-Petit A et al. · 2026 · Theoretical population biology
Hymenoscyphus fraxineus is an invasive forest fungal pathogen that induces severe dieback in European ash populations. The spread of the disease has been closely monitored in France by the forest health survey system which has made it…
View details →DOI: 10.1016/j.tpb.2026.06.006 Negative / Null Result ReportMedicine
Arian Namazi S, Sadeghi S, Kiani M · 2026 · Scientific reports
Several studies have investigated the immediate impact of viewing fantastical television (TV) programs on children's cognitive function; however, the results have been inconsistent. This study experimentally investigates the immediate…
View details →DOI: 10.1038/s41598-026-54794-5 Negative / Null Result Report
Erfanikia A, Hajikarimi B, Nazari A et al. · 2026 · Preprint
Abstract This study investigates the complex interplay between strategic orientation, internal capabilities, and external environmental forces in shaping the export performance of Small and Medium-sized Enterprises (SMEs). Specifically, it…
View details →DOI: 10.21203/rs.3.rs-8924474/v1 Failed Experiment Report
Laure T, Boffo M, Konigorski S et al. · 2026 · Preprint
BackgroundOne in four university students face mental health challenges, underscoring the need for effective support systems. Within Erasmus University Rotterdam student wellbeing initiative, we developed a mobile intervention providing…
View details →DOI: 10.31234/osf.io/pbcv4_v2 Failed Experiment ReportMedicine
Edwards MA, Petty SB, Chawla K et al. · 2026 · American journal of surgery
Objectives This retrospective cohort of patients undergoing surgery from 2019 to 2023 evaluated the association between individual-level social drivers of health (SDoH) and postoperative outcomes (length of stay, 30-day mortality, 30-day…
View details →DOI: 10.1016/j.amjsurg.2026.116890 Negative / Null Result Report
Ghayad C, Menhall A, Makary C et al. · 2026 · Preprint
Abstract Background This study aims to determine how Lebanese dentists manage postoperative dental pain following oral surgery, with a specific focus on opioid use in Lebanon. Methods An anonymous online survey was conducted to assess…
View details →DOI: 10.21203/rs.3.rs-9909133/v1