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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19885 results in Negative / Null Result Report · page 514 of 663

Negative / Null Result ReportOpen accessEngineering geology. Rock mechanics. Soil mechanics. Underground construction

INFLUENCE OF NITROGEN SOURCES ON GROWTH, YIELD, SOME MACRO AND MICRONUTRIENTS CONTENT OF MAIZE PLANT (Zea mays, L.) IN SALT AFFECTED SOILS

M.M.A. Bader, H.Z. Abd El-Salam, M.R. Mohamed et al. · 2004 · Journal of Soil Sciences and Agricultural Engineering

Two field experiments were conducted at the Experimental Station of Agricultural Research Station at Tag EI·Ezz Dakahlia Governorate during 2000 and 2001 seasons. The used soil was salt affected one. The research aims to study the effect of N-NO'3, N-NH+4 or N-urea on yield and some characters of maize plant as well as macro-micronutrients content in ear leaves at maturity stage (physiological stage) and seeds. Single hybrid CS 10 of maize was used as testing plant within two seasons (2000 and 2001) and the soil salinity levels were 1.69, 5.3 and 11.10 dS/m in 2000, and 1.69, 5.43 and 11.10 ds

View details →DOI: 10.21608/jssae.2004.240847
Negative / Null Result ReportOpen accessMedicine

Application and limitation of a biological clock-based method for estimating time of death in forensic practices

Akihiko Kimura, Yuko Ishida, Mizuho Nosaka et al. · 2023 · Scientific Reports

Abstract Estimating time of death is one of the most important problems in forensics. Here, we evaluated the applicability, limitations and reliability of the developed biological clock-based method. We analyzed the expression of the clock genes, BMAL1 and NR1D1, in 318 dead hearts with defined time of death by real-time RT-PCR. For estimating the time of death, we chose two parameters, the NR1D1/BMAL1 ratio and BMAL1/NR1D1 ratio for morning and evening deaths, respectively. The NR1D1/BMAL1 ratio was significantly higher in morning deaths and the BMAL1/NR1D1 ratio was significantly higher in e

View details →DOI: 10.1038/s41598-023-33328-3
Negative / Null Result ReportOpen accessPsychology

Pembelajaran E-Learning Perkembangan Anak di Jurusan Psikologi

Riza Noviana Khoirunnisa, Damajanti Kusuma Dewi, Desi Nurwidawati · 2018 · Jurnal Psikologi Teori dan Terapan

Conventional learning method is viewed to be less effective because it poses the problems of space and time. Information Technology offers a method for more effective online learning called e-learning. This research aims to develop e-learning for the module of Child Development at Department of Psychology Universitas Negeri Surabaya. This study was a developmental research project that used the method of ADDIE (Analysis, Design, Development, Implementation, Evaluation). This model was chosen because the stages of its development are deemed appropriate especially for the refinement and implemen

View details →DOI: 10.26740/jptt.v9n1.p62-76
Negative / Null Result ReportOpen accessAgriculture (General)

Combined effects of landscape composition and pesticide use on herbivore and pollinator functions in smallholder farms

Quentin Struelens, Diego Mina, Olivier Dangles · 2021 · CABI Agriculture and Bioscience

Abstract Background Landscape composition has the potential to foster regulating ecosystem services such as pollination and biocontrol in temperate regions. However, most landscape studies do not take pesticide use into account even though it is the main control strategy worldwide and has negative impacts on beneficial insects. Moreover, few studies have explored these combined effects in smallholder cropping system with diverse landscapes and small cultivated fields. Methods We assessed the effect of semi-natural cover and pesticide use on pollinator and herbivore abundances and functions in

View details →DOI: 10.1186/s43170-021-00027-w
Negative / Null Result ReportOpen accessAnimal culture

Evaluation of production efficiencies at pasture of lactating suckler cows of diverse genetic merit and replacement strategy

S. McCabe, N. McHugh, N.E. O’Connell et al. · 2020 · Animal

Feed costs account for the largest proportion of direct cost within suckler beef production systems. By identifying the cow type with enhanced capability of converting grazed herbage to beef output across lactations, suckler cow systems would become more efficient and sustainable. The objective of this study was to estimate grass DM intake (GDMI) and production efficiency among lactating suckler cows of diverse genetic merit for the national Irish maternal index (Replacement Index) which includes cow efficiency components such as milk yield and feed intake. Data from 131 cows of diverse geneti

View details →DOI: 10.1017/s1751731120000415
Negative / Null Result ReportOpen accessAgriculture

The Effect of Ethanolic Extract of Melilotus officinal Flowers on Bleeding Time in Male and Female Rabbits

Hassan Toama Mohamed, Ali Sami Amen · 2012 · Al-Qadisiyah Journal For Agriculture Sciences

The present study aimes to examining the effect of the ethanolic extract of Melilotus officinalis flowers on bleeding time ,WBC and RBC count .Total number in males and females adult rabbit eighteen, (9 males and 9females ) are randomly divided into three equal groups (3 males and 3females per group). The first (control) is drenched normal saline while the second and third groups are drenched the ethanolic extracted (20 and 50mg/ml/kg of B.W) for 24 hours. The results reveal significant increase in bleeding time in third group followed by the second group compared with the control while RBC an

View details →DOI: 10.33794/qjas.2012.68153
Negative / Null Result ReportOpen accessVeterinary medicine

EFFECT OF USING DIFFERENT COLORED LED LIGHTS ON GONADS, EGG NUMBER AND WEIGHT IN JAPANESE QUAILS

İsmail Gökçe Yildirim, Ece Koc Yildirim, Firuze Turker Yavas · 2025 · Slovenian Veterinary Research

Artificial lighting plays a crucial role in regulating the maturation of the reproductive system of birds during puberty and thus affects their reproductive capacity. The aim of this study was to investigate the morphometric effects of the use of different coloured light-emitting diodes (LEDs) on the gonads of male and female Japanese quail (Coturnix coturnix japonica). The experimental groups were also examined with regard to egg count, weight, fertility and hatchability. A total of 240 quails of mixed sex were subjected to three different light colours, namely white, green and blue LEDs. The

View details →DOI: 10.26873/svr-1925-2024
Negative / Null Result ReportOpen accessPsychology

Audio-Visual Spatiotemporal Perceptual Training Enhances the P300 Component in Healthy Older Adults

Weiping Yang, Weiping Yang, Ao Guo et al. · 2018 · Frontiers in Psychology

In older adults, cognitive abilities, such as those associated with vision and hearing, generally decrease with age. According to several studies, audio-visual perceptual training can improve perceived competence regarding visual and auditory stimuli, suggesting that perceptual training is effective and beneficial. However, whether audio-visual perceptual training can induce far-transfer effects in other forms of untrained cognitive processing that are not directly trained in older adults remains unclear. In this study, the classic P300 component, a neurophysiological indicator of cognitive pr

View details →DOI: 10.3389/fpsyg.2018.02537
Negative / Null Result ReportOpen accessProbabilities. Mathematical statistics

The Association Between Performance and Mathematical Subjects Among Diploma Students

Ilya Zulaikha Zulkifli, Nor Faezah Mohamad Razi, Nor Hazlina Mohammad et al. · 2024 · Journal of Computing Research and Innovation

Over recent semesters, the increasing failure rates in STA108 have raised concerns about this course's teaching and learning environment. This issue has prompted an investigation into potential contributing factors, focusing on three main objectives: examining the students’ association between gender and MAT133, exploring the relationship between students’ achievements in MAT133 and their Mathematics grades in the Sijil Pelajaran Malaysia (SPM), and assessing the association between STA108 results and their Mathematics grades in the Sijil Pelajaran Malaysia (SPM). The respondents completed 329

View details →DOI: 10.24191/jcrinn.v9i2.443
Negative / Null Result ReportOpen accessInfectious and parasitic diseases

High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo

Deby Mukendi, Jean-Roger Lilo Kalo, Pascal Lutumba et al. · 2021 · BMC Infectious Diseases

Abstract Background The epidemiology of human cysticercosis and neurocysticercosis, caused by the larval stage of the pork tapeworm Taenia solium, is not well known in the Democratic Republic of Congo (DRC). Within a multicenter etiological and diagnostic study conducted by the NIDIAG consortium (“Better Diagnosis for Neglected Infections”) and investigating several challenging syndromes, we consecutively evaluated from 2012 to 2015 all patients older than 5 years presenting with neurological disorders (neurology cohort) and with fever > 7 days (persistent fever cohort) at the rural hospital o

View details →DOI: 10.1186/s12879-021-06032-8
Negative / Null Result ReportOpen accessMedicine

Is genu varum a risk factor for the prevalence and severity of achilles tendinopathy? A cross-sectional study of Nigerian elite track and field athletes

Ayoola Ibifubara Aiyegbusi, Bosede Abidemi Tella, Ganiyat Adebanke Sanusi · 2020 · Nigerian Postgraduate Medical Journal

Background: Achilles tendinopathy (AT) is one of the most frequently reported ankle and foot overuse injuries. Prior studies have reported altered biomechanical variables of the lower limb as risk factors for the prevalence and severity of AT in athletes, especially in Caucasians, but there are few reports on African elite athletes. Because it is established that anthropometric and biomechanical values vary with racial disposition, this study was designed to investigate the association between selected physical and biomechanical variables of the lower limb and the prevalence and severity of AT

View details →DOI: 10.4103/npmj.npmj_179_19
Negative / Null Result ReportOpen accessMedicine (General)

Genotype Combination of rs1042044 and rs6458093 in GLP-1R as A Genetic Risk for Osteoporosis in Postmenopausal Iraqi Women

Ammar Kadhim Alzubaidi, Farah Abdulwahab Al-Saadi, Amer Qani Alagele · 2025 · Indonesian Biomedical Journal

BACKGROUND: Many genetic factors are known to be related to osteoporosis, and currently the role of the glucagon-like peptide-1 receptor (GLP-1R) gene in bone health has been studied intensively. Some variation of this gene, such as rs1042044 and rs6458093, are known to be linked to metabolic diseases and lower bone mineral density, however their specific contribution to osteoporosis remains largely unexplored. Therefore, this study was conducted to investigate the combined genotypic effect of rs1042044 and rs6458093 as a genetic risk factor for osteoporosis in postmenopausal Iraqi women. METH

View details →DOI: 10.18585/inabj.v17i5.3768
Negative / Null Result ReportOpen accessMedicine

The dietary patterns of 12-year-old children and their awareness about the effect of diet on oral health in Iran

Maryam Rad, Arash Shahravan, Ali Akbar Haghdoost · 2017 · Journal of Oral Health and Oral Epidemiology

BACKGROUND AND AIM: Foods containing carbohydrates have a major effect on the pathogenesis of dental caries. There is a direct correlation between frequency of consumption of foods containing sugar and dental caries. The purpose of this study was to evaluate the dietary patterns of 12-year-old children and their awareness about the effect of diet on oral health in Iran. METHODS: A cross-sectional survey was conducted on 1554 children aged 12 years in 5 provinces in Iran. Subjects were selected based on a multistage stratified cluster random sampling procedure. Data were collected by a cultural

Negative / Null Result ReportOpen accessMedicine

Estimation of Serum Ferritin Levels in Blood Donors and its Association with Frequency of Blood Donation and Blood Indices

Amrita S Kumar, A Geetha, Jim Joe et al. · 2021 · Journal of Clinical and Diagnostic Research

Introduction: Blood donation is one of the most significant contributions that a person can make towards the society. A donor generally donates maximum 450 mL of blood at the time of donation. If 450 mL of blood is taken in a donation, men lose 242±17 mg and women lose 217±11 mg of iron. Hence, adequate iron stores are very important in maintenance of the donor’s health. Aim: To assess the influence of frequency of blood donation on iron levels of blood donors by estimating Haemoglobin (Hb) and other blood indices which reflect iron status of blood and serum ferritin which reflects body iron s

View details →DOI: 10.7860/jcdr/2021/48168.14810
Negative / Null Result ReportOpen accessNursing

Association Between Serum 25-Hydroxyvitamin D Levels and Gross Motor Development in Children With Down Syndrome: An Analytical Cross-Sectional Study

Esmire Tërshnjaku Sadiku, Lence Aleksovska Velickovska, Samire Beqaj et al. · 2026 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija

Background. Down syndrome (DS) is associated with delayed gross motor development, and vitamin D deficiency is frequently reported in this population. However, evidence regarding the relationship between vitamin D status and motor development in children with DS is limited. Aim. To examine the association between serum 25-hydroxyvitamin D [25(OH)D] levels and gross motor development in children with DS. Methods. This analytical cross-sectional study included 33 children with DS (13 females and 20 males) aged 1.00–6.56 years (mean age 2.53 ± 1.06 years). Gross motor development was assessed usi

View details →DOI: 10.33607/rmske.v1i34.2277
Negative / Null Result ReportOpen accessMedicine

Unmet Nutritional and Psychological Needs of Cancer Patients: An Integrated Multi-Professional Model Approach

Giuseppe Carruba, Maria Luisa Calagna, Ildegarda Campisi et al. · 2022 · Diseases

This paper presents a multi-professional integrated approach toward the recognition and management of the nutritional and psychological needs of cancer patients. In particular, the patients undertook a multi-professional, multistep process that included the collection of both personal and clinical data, the evaluation of anthropometric measures, nutritional status and psychometric indices, and an ensuing personalized nutritional prescription and psychological support, ultimately leading to combined nutritional and psychological interventions to control their adherence to a nutritional program

View details →DOI: 10.3390/diseases10030047
Negative / Null Result ReportOpen accessMedicine

Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study.

Davis C Woodworth, Adelle Dagher, Adam Curatolo et al. · 2018 · PLoS ONE

The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has yielded neuroimaging and urinary biomarker findings that highlight unique alterations in brain structure and in urinary proteins related to tissue remodeling and vascular structure in patients with Urological Chronic Pelvic Pain Syndrome (UCPPS). We hypothesized that localized changes in diffusion tensor imaging (DTI) measurements might be associated with corresponding changes in urinary protein levels in UCPPS. To test this hypothesis, we created statistical parameter maps depicting the linear corre

View details →DOI: 10.1371/journal.pone.0206807
Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens

Dietary Patterns and Breast Cancer Risk: A KCPS-II Cohort Study

Ji-Young Lee, Hae In Cho, Heejin Kimm · 2024 · European Journal of Breast Health

Objective: There have been inconsistencies in the evidence for a role of dietary patterns in the development of breast cancer. In this study, we used a large-scale cohort [Korean Cancer Prevention Study-II (KCPS-II)] to examine the association between dietary patterns and breast cancer risk in Korean women. Materials and Methods: The dietary patterns of 14,807 women from the KCPS-II were derived by factor analysis and 135 cases of breast cancer were diagnosed during the follow-up period. Cox proportional models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) fo

View details →DOI: 10.4274/ejbh.galenos.2024.2024-3-4
Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology

PATTERNS OF ALCOHOL CONSUMPTION AND MENTAL HEALTH IN HCV-INFECTED PATIENTS: IMPLICATIONS FOR ANTIVIRAL ELIGIBILITY

Lívia Beraldo de LIMA, André MALBERGIER, Priscila Dib GONÇALVES et al. · 2025 · Arquivos de Gastroenterologia

ABSTRACT Background: Hepatitis C virus (HCV) infection remains a significant public health concern. Behavioral factors such as alcohol use and psychiatric comorbidities, particularly depression, may influence disease progression and eligibility for antiviral treatment. Objective: To assess the prevalence and clinical impact of current alcohol consumption in patients with chronic HCV infection eligible for treatment with direct-acting antivirals (DAAs), and to explore its associations with depressive symptoms and clinical characteristics. Methods: This was a cross-sectional study including 109

View details →DOI: 10.1590/s0004-2803.24612025-054
Negative / Null Result ReportOpen accessMedicine

Association between obesity and mortality from hematological malignancies among Japanese adults: The Japan Collaborative Cohort study.

Hana Wakasa, Satoshi Sunohara, Takashi Kimura et al. · 2025 · PLoS ONE

Obesity is a growing global health concern and has been associated with increased mortality from various cancer types, including hematological malignancies. However, evidence for this association in Asian populations, particularly among Japanese adults, remains limited. Thus, this study aimed to examine the association between obesity and mortality due to hematological malignancies. Data from 97,073 participants in the Japan Collaborative Cohort (JACC) Study were analyzed. The participants were followed for a mean duration of 17 years. Body mass index (BMI) was calculated using self-reported h

View details →DOI: 10.1371/journal.pone.0335750
Negative / Null Result ReportOpen accessTherapeutics. Pharmacology

TSH-β gene polymorphism in Saudi patients with thyroid cancer: A case-control study

Maha M. AlRasheed · 2022 · Saudi Pharmaceutical Journal

Background: The role of thyroid-stimulating hormone in the pathogenesis of thyroid cancer is not yet fully explored. This study aimed to evaluate the role of the TSH-β polymorphism in thyroid cancer in a Saudi cohort. Methods: A prospective case-control study was conducted on 507 patients with differentiated thyroid carcinoma and compared them with 560 controls of Saudi origin. The association of two variants, the rs201857310, and rs7530810, in the TSH-β gene with thyroid cancer risk as well as thyroxine dose, were evaluated. Results: The rs201857310_A > G [OR: 0.50 (95 % CI: 0.35–0.71); P < 0

View details →DOI: 10.1016/j.jsps.2022.07.015
Negative / Null Result ReportOpen accessNursing

The Relationship between Spiritual Well-Being and Depression in Nursing Students

Z Gharehboghlou, M Adib-Hajbaghery, M Hajimohammad Hoseini · 2016 · نشریه پرستاری ایران

Abstract Background & Aim: Depression is the fourth leading cause of community disability in the world and it has high prevalence among students. Since spirituality is positively associated to physical and mental health, this study aimed to determine the relationship of spiritual well-being and depression among nursing students in Qom and Kashan Universities of Medical Sciences. Materials & Methods: This cross-sectional study was conducted on nursing students of Kashan and Qom Universities of Medical Sciences. Using a two-stage sampling method, 250 nursing students were randomly selected. Data

Negative / Null Result ReportOpen accessAnesthesiology

Study of the impact of training of registered nurses in cardiopulmonary resuscitation in a tertiary care centre on patient mortality

Mayureshkumar Pareek, Vandana Parmar, Jigisha Badheka et al. · 2018 · Indian Journal of Anaesthesia

Background and Aims: Nurses should have cardiopulmonary resuscitation (CPR) knowledge and skills to be able to implement effective interventions during in-hospital cardiac arrest. The aim of this descriptive study was to assess mortality impact after nurses' CPR training with pre-CPR training data at our institute. Methods: Training regarding CPR was given to nurses, and CPR mortality 1-year before basic life support (BLS) and advanced cardiac life support (ACLS) training were collected and compared with post-training 1-year CPR mortality. Results: A total of 632 adult patients suffering in-ho

View details →DOI: 10.4103/ija.ija_17_18
Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens

TGFBR1 Polymorphism and Risk of Breast Cancer in Iranian Women

Elahe Kamali, Simin Hemmati, Forouzan Safari et al. · 2015 · The International Journal of Biological Markers

Numerous epidemiological studies have evaluated the association between transforming growth factor beta receptor type 1 ( TGFBR1 ) polymorphisms and the risk of cancer; however, the results remain inconclusive and controversial. To determine the association between breast cancer risk and the *6A polymorphism of the TGFBR1 gene, a case-control study of 280 breast cancer patients and 280 controls was performed in Iranian women. Our study demonstrates that women who carry the TGFBR1*6A allele are at lower risk of developing breast cancer. The highest protection against breast cancer was observed

View details →DOI: 10.5301/jbm.5000102
Negative / Null Result ReportOpen accessPublic aspects of medicine

Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

A Aleyasin, M Ghazanfari, M Houshmand · 2010 · Iranian Journal of Public Health

&quot;nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision.&nbsp; The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon&shy;dary genetic and/or epigenetic risk factors are suggested to influence its neuropathology.&nbsp; In this study folate gene polymor&shy;phisms were examined as a possible LHON secondary genetic risk factor in Iranian patients.&quot;nMethods: Common polymorphisms in the MTHFR (C677T and A1298C) and MTRR (A66G) genes were tested in 21 LHON pa

Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens

Immunohistochemical Expression of Programmed Death-Ligand 1 Associated with Human Papillomavirus-Driven High-Grade Cervical Intraepithelial Neoplasia in South African Women

Jessica McIntyre, Rahaba Marima, Babatunde Alabi et al. · 2026 · Onco

Background: Cervical cancer is the second most prevalent malignancy among South African women, with high-risk human papillomavirus (HPV) infection as a critical risk factor. HPV plays a central role in cervical carcinogenesis, particularly in high-grade squamous intraepithelial lesions (HSIL). Increased programmed death ligand 1 (PD-L1) expression has been implicated in cervical carcinoma tumorigenesis. Using immunohistochemistry, this study investigated the correlation between high-risk HPV-driven cervical intraepithelial neoplasia (CIN) and PD-L1 expression. Methods: An analytical cross-sect

View details →DOI: 10.3390/onco6010014
Negative / Null Result ReportOpen accessFinance

Implied Volatility of Call Options and Abnormal Stock Returns: Evidence From Quantile Analysis of Abnormal Return Determinants

Sayyede Elnaz Afzaliyan Boroujeni, Abdolmajid Abdolbaghi Ataabadi, Naser Khani · 2025 · Mathematics and Modeling in Finance

The present study aims to assess the impact of implied volatility (IV) extracted from call option prices on abnormal stock returns. IV, as a critical market volatility index, plays an essential role in explaining investor behavior. The Black-Scholes model was used to extract IV, applying Brent’s method due to the absence of an explicit closed-form solution. In addition, daily call option trading data from the Tehran Stock Exchange (TSE) were utilized during 2016-24. Further, quantile multivariate regression, along with wild bootstrap resampling (1,000 repetitions), was employed for model estim

View details →DOI: 10.22054/jmmf.2025.87610.1205
Negative / Null Result ReportOpen accessMedicine

Interplay between lipid profiles, thyroid function, and gallstone disease: A clinical perspective

Vivek Nagappa, Akhila Bhandarkar · 2025 · Journal of Family Medicine and Primary Care

Background: New research points to a complicated relationship between gallstone disease (GSD), thyroid function, and lipid profiles. To better understand how to prevent and treat GSD, this study will look at how common thyroid abnormalities are among people with the diagnosis, as well as any dyslipidemias that may be present. Material and Methods: This is a cross-sectional observational study worked out at a tertiary care hospital in southern India’s Department of General Surgery. We enrolled 60 persons with a GSD diagnosis. We divided patients with only gallstones and gallstones with common b

View details →DOI: 10.4103/jfmpc.jfmpc_1772_24
Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology

Polymorphism analysis of estrogen receptor β Gene RsaI and AluI in girls with idiopathic central precocious puberty: investigating the relationship and implications for early risk prediction

Peipei Liu, Guoqing Dong, Mingzhu Li et al. · 2026 · Frontiers in Endocrinology

ObjectiveTo investigate the association between estrogen receptor β (ERβ) gene RsaI (rs1256049) and AluI (rs4986938) polymorphisms and the risk of idiopathic central precocious puberty (ICPP) in girls, and to provide potential molecular genetic references for early risk prediction and individualized management of ICPP.MethodsA total of 100 girls with ICPP from the Pediatric Endocrinology Clinic and Inpatient Ward of Shenzhen Maternity & Child Healthcare Hospital were enrolled, and 100 agematched healthy girls undergoing routine physical examinations during the same period served as controls. T

View details →DOI: 10.3389/fendo.2026.1809152
Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology

Glycemic control and asymptomatic carotid plaque and carotid intima–media thickness

Xingquan Zhao, Qian Zhang, Shengyun Chen et al. · 2025 · BMJ Open Diabetes Research & Care

Introduction The effects of different glucose metabolic states and diabetes-controlled status on asymptomatic carotid atherosclerosis has not been well investigated. Herein, we aimed to investigate the association of different diabetes status with asymptomatic carotid plaques and carotid intima–media thickness (CIMT).Research design and methods 4752 participants aged over 40 years, free of stroke or myocardial infarction, from the China National Stroke Screen Survey programme were enrolled. Carotid plaque and CIMT were assessed using duplex ultrasonography. Logistic regression analysis was use

View details →DOI: 10.1136/bmjdrc-2024-004786