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Negative / Null Result ReportOpen accessNursing

Association Between Serum 25-Hydroxyvitamin D Levels and Gross Motor Development in Children With Down Syndrome: An Analytical Cross-Sectional Study

Esmire Tërshnjaku Sadiku; Lence Aleksovska Velickovska; Samire Beqaj; Mejdi Aliu · 2026 · Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija

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The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background. Down syndrome (DS) is associated with delayed gross motor development, and vitamin D deficiency is frequently reported in this population. However, evidence regarding the relationship between vitamin D status and motor development in children with DS is limited. Aim. To examine the association between serum 25-hydroxyvitamin D [25(OH)D] levels and gross motor development in children with DS. Methods. This analytical cross-sectional study included 33 children with DS (13 females and 20 males) aged 1.00–6.56 years (mean age 2.53 ± 1.06 years). Gross motor development was assessed usi

Abstract by Esmire Tërshnjaku Sadiku; Lence Aleksovska Velickovska; Samire Beqaj; Mejdi Aliu, Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija (2026) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.33607/rmske.v1i34.2277