A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21328 results · page 489 of 711
Sommer K, Russell S, Paynter J · 2026 · Preprint
This pre-registered study examined whether autistic preschool children could learn novel words from a social robot during a shared eBook reading session, how their engagement with the robot relates to word learning, and whether their…
Meade-Aguilar JA, Stovall R, Ramiro S et al. · 2026 · Joint bone spine
Objectives There are limited data on how NSAID use and dosage influence hypertension risk in axial spondyloarthritis (axSpA). We evaluated the association between NSAID use and incident hypertension in a longitudinal axSpA inception…
Gonzalez DE, Dickerson BL, Hines K et al. · 2026 · Sports (Basel, Switzerland)
There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. This analysis investigated whether the dose or duration of CrM was associated with SEs.…
Aljarallah S, Aldeligan SH, Almarshed A et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PURPOSE.: Restless legs syndrome (RLS) is a common but under-recognised non-motor symptom in multiple sclerosis (MS), potentially linked to central nervous system lesion distribution. This study aimed to assess the anatomical distribution…
Yıldız P, Yurtseven A, Turan C et al. · 2026 · BMC pharmacology & toxicology
Methylphenidate is widely prescribed for attention-deficit/hyperactivity disorder, and its use has increased substantially in recent years. Although generally considered safe within therapeutic ranges, supratherapeutic ingestion may result…
Haksever M, Taşdemir D · 2026 · BMC pregnancy and childbirth
To evaluate the association between maternal hemoglobin and ferritin levels and fetal cortical maturation assessed by neurosonography between 30 and 34 weeks of gestation. This prospective observational study included 187 singleton…
Kaushik A, Jaiswal A, Priya B et al. · 2025 · Journal of family medicine and primary care
Background Breast cancer is the most common cancer in women across the world. Immune cells can detect and destroy cancer cells. However, cancer cells acquire certain immune evasion mechanisms such as PD-1+ T-cells, to combat immune…
Zhou X · 2026 · Translational psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown. We developed a new method to more…
Isikoglu BD, Senler FC · 2026 · Preprint
Abstract Purpose. Insomnia is a heterogeneous symptom cluster of multiple etiologies, frequently encountered in oncology patients, and chemotherapy has been implicated as a contributing factor. We aimed to evaluate the effects of…
Coban S, Yavuz S, Dogan C et al. · 2026 · Preprint
Abstract Background Emergency department overcrowding is a persistent global public health issue, often driven by non-urgent visits. Health literacy is considered a key determinant of appropriate healthcare utilization. Objective This…
Hiroshimaya T, Iwai K, Marutani M et al. · 2026 · Scientific reports
This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. Periodontitis…
Amuji DN, Iweala EEJ · 2026 · BMC cancer
BACKGROUND: Breast cancer (BC) is a major cause of cancer-related mortality among women worldwide. Genetic polymorphisms, such as those in the Mesenchymal Epithelial Transition factor (MET) proto-oncogene, may influence cancer risk and…
Liu Y, Zhong S, Zhong K et al. · 2026 · Frontiers in endocrinology
Aim To investigate the association between history of gestational diabetes mellitus (GDM) and the risk of hypertensive disorders of pregnancy in subsequent pregnancy (s-HDP). Methods A retrospective cohort of 5, 928 women with two…
Haddad A, Zabari Parnis E, Stein N et al. · 2026 · Vaccines
Background/Objective : The emergence of the COVID-19 pandemic has raised significant concerns regarding its impact on immune-mediated diseases, particularly with respect to disease induction and exacerbation. We aimed to investigate the…
Wu Z, He S, Zhu F et al. · 2026 · Frontiers in endocrinology
Objective Copper overload has been implicated in impaired β -cell function and insulin resistance through oxidative stress and inflammatory pathways. As a major lipoprotein component involved in lipid oxidation, apolipoprotein B (apoB) may…
Macian N, Dualé C, Delay M et al. · 2026 · European journal of pain (London, England)
Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was…
Alharthy N, Alreefi M, Alsenani M et al. · 2026 · Pediatric health, medicine and therapeutics
Background Among children younger than 5 years, infectious conditions account for the majority of pediatric emergency department visits. Due to nonspecific presentation, early identification of Sepsis and serious bacterial infection is…
Uka-Kalu EC, Egesimba NC · 2026 · Preprint
Abstract Background: Drowning is a significant but often neglected public health issue, with low- and middle-income countries bearing a disproportionate burden. Young adults, particularly university students, represent a high-risk group…
Buhari HM, Akpan SN, Ballah FM et al. · 2026 · Preprint
Abstract Foodborne illnesses remain a significant public health challenge in low and middle-income countries. Local food vendors operating in informal settings represent a critical point of intervention, yet their food hygiene knowledge…
Önder N, Muratoglu K · 2026 · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
Peanuts are among the most clinically important food allergens and may cause severe reactions even at very low exposure levels. This study investigated the presence of peanut residues in packaged baby biscuits marketed on the European side…
Zeng Y, Zhu Y, Liu W et al. · 2026 · Preprint
Abstract Background When the function of one kidney is impaired or lost, the contralateral kidney may exhibit varying degrees of compensatory response. However, the influencing factors and underlying mechanisms of renal compensation remain…
Ntombana L, Dlatu N, Hosu MC · 2026 · Preprint
Background: /Objectives: The growing burden of multidrug-resistant tuberculosis (MDR-TB), driven by poor treatment adherence and limited diagnostic access, has complicated disease control efforts. The recent introduction of shorter, less…
Mirmosayyeb O, Barzegar M, Rezaei M et al. · 2026 · Neurologia
Purpose Multiple sclerosis (MS) is a debilitating disease accompanied by physical and mental comorbidities. Little is known about the relation between different comorbidities and health-related quality of life (HRQOL) in people with MS…
Kumar MC, Ashok A · 2026 · Preprint
Abstract Background Cardiovascular diseases (CVDs) remain the leading cause of mortality globally. Cardiac rehabilitation (CR) is an effective intervention to improve recovery and reduce recurrence; however, nurses’ knowledge and attitude…
Kanani P, Shinde V, Bhimani K et al. · 2026 · Annals of African medicine
Background Shock is a critical, life-threatening syndrome defined by a state of global hypoperfusion that results in inadequate oxygen and nutrient delivery to tissues, leading to cellular dysfunction and ultimately, organ failure. Despite…
Kądziela M, Migdalska-Sęk M, Domańska-Senderowska D et al. · 2026 · International journal of molecular sciences
Vitiligo is a chronic autoimmune skin disorder characterized by progressive melanocyte loss and depigmented skin lesions, whose pathogenesis has been attributed to genetic and immunological factors. The aim of this exploratory study was to…
Anderson N, Kimlin K, O'Rourke JL et al. · 2026 · Pediatric research
Background Congenital hearing loss can significantly affect childhood development, yet more than half of affected infants present without identifiable risk factors. A possible association between maternal diabetes and congenital hearing…
Li Y, Zhu YX, Qiu Y et al. · 2026 · Clinical nephrology
Objective The association between the atherogenic index of plasma (AIP) and chronic kidney disease (CKD) among individuals with different metabolic syndromes remains inadequately characterized. The aim of this study is to assess the…
Mostofi K, Caragliano G · 2026 · The Journal of hospital infection
Background Surgical site infections (SSIs) are a major complication of spinal surgery. The influence of tattoos overlying the operative incision has not been previously evaluated as a risk factor in this context. Methods Retrospective…
Chen F, You R, Liu Y et al. · 2026 · Preprint
Background and Aims MASLD has become the most prevalent chronic liver disease globally. Although MVPA and plasma fatty acids have been individually studied in relation to metabolic health, their independent and combined associations with…