Negative / Null Result ReportMedicine
Isaacson BN, Serbin SP, Grabosky JC · 2025 · Forest Ecology and Management.
There is a vigorous debate around whether and how to manage forests for climate mitigation or for other goals such as biodiversity. To achieve any of these goals it is necessary to define the parameters within which they can exist;…
Negative / Null Result ReportOpen accessMedicine
Kanyorszky ET, Sterczer Á, Vizi Z et al. · 2026 · BMC veterinary research
BACKGROUND: Acute pancreatitis triggers the production of acute-phase proteins (APPs) in the body, among which C-reactive protein (CRP) is the most extensively studied and widely used for both diagnosis and prognosis. The diagnostic value…
View details →DOI: 10.1186/s12917-026-05409-8 Negative / Null Result Report
Ghamgosar Shahkhali M, Liu L, Ghamgosar Shahkhali MH et al. · 2025 · Preprint
Objective To explore potential genetic and/or causal associations between Post-Traumatic Stress Disorder and neurodegeneration-related isolated/idiopathic rapid-eye-movement sleep behavior disorder. Methods We conducted polygenic risk…
View details →DOI: 10.1101/2025.09.05.25335205 Negative / Null Result ReportMedicine
Yang T, Yuan X, Gao W et al. · 2024 · Internal and emergency medicine
Observational studies revealed paradoxically inverse associations between diabetes and aortic diseases (aortic aneurysm or aortic dissection), yet the causality remains to be determined. To investigate the causal associations between…
View details →DOI: 10.1007/s11739-024-03727-z Negative / Null Result ReportOpen accessMedicine
Zhang H, Zhao T, Zheng H et al. · 2026 · BMC neurology
Neuronal intranuclear inclusion disease (NIID) is a rare, progressive neurodegenerative disorder caused by abnormal GGC repeat expansions in the NOTCH2NLC gene, leading to multisystem involvement. Electrophysiological abnormalities in NIID…
View details →DOI: 10.1186/s12883-026-04898-2 Negative / Null Result ReportMedicine
Berger M, Bruggisser F, Schwarz A et al. · 2025 · Physiology & behavior
Objectives To investigate whether a single session of aerobic exercise improves inhibitory control in preadolescent children and whether this effect is mediated by changes in parasympathetic activity. Design In this experimental study, an…
View details →DOI: 10.1016/j.physbeh.2025.114820 Failed Experiment ReportMedicine
Martinez G, Tolentino K, Sukheja P et al. · 2025 · Bioorganic & medicinal chemistry letters
Screening of the ChemDiv molecular library in cholesterol media against Mycobacterium tuberculosis (Mtb) H37Rv strain identified a novel isoxazole thiophene hit as a putative Rv1625c/Cya activator with a promising in vitro activity and…
View details →DOI: 10.1016/j.bmcl.2025.130108 Negative / Null Result Report
Su Z, Wyble B, Fu Y · 2024 · Preprint
This study explores the relationship between working memory and attention during visual search tasks, focusing on how time constraints affect the encoding of visual information into working memory. The research is based on the premise that…
View details →DOI: 10.31234/osf.io/d4hc5 Negative / Null Result ReportMedicine
de Bruin LJE, Hoegh M, Greve C et al. · 2024 · The Journal of orthopaedic and sports physical therapy
OBJECTIVE: To assess the causal role of the relationship between loading and the onset of nonspecific low back pain (NSLBP) and persistence of NSLBP (chronic low back pain [CLBP]). DESIGN : Scoping review. LITERATURE SEARCH : We searched…
View details →DOI: 10.2519/jospt.2024.11314 Negative / Null Result ReportOpen accessMedicine
· 2024 · Journal of cellular and molecular medicine
Xin Li, Hao Xu, Jianfeng Yi, Chunlu Dong, Hui Zhang, Zhengfeng Wang, Long Miao, Wence Zhou. miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT…
View details →DOI: 10.1111/jcmm.18188 Negative / Null Result ReportMedicine
Power MC, Lynch KM, Fang V et al. · 2025 · Environmental research
Background As dementia has a decades-long preclinical phase, earlier air pollution exposures may be more etiologically relevant to dementia risk than more recent exposures. Methods We estimated exposures at Atherosclerosis Risk in…
View details →DOI: 10.1016/j.envres.2025.122850 Negative / Null Result ReportMedicine
Kömürcü HF, Sever N, Gökdereli NS et al. · 2025 · Neurological research
Background It has been suggested that smokers have higher recanalization rate, lower risk of cerebral hemorrhage and better prognosis than non-smokers (smoking paradox) after reperfusion therapy in patients with acute ischemic stroke (IS).…
View details →DOI: 10.1080/01616412.2024.2448628 Negative / Null Result ReportMedicine
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of Dairy Science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
Negative / Null Result Report
Xu C, Yang G, Liu Y · 2024 · Preprint
Abstract Background Obstructive Sleep apnea (OSA) is a prevalent sleep disorder characterized by repetitive interruptions of breathing during sleep, significantly impacting cardiovascular and metabolic health. Epigenetic aging, measured…
View details →DOI: 10.21203/rs.3.rs-5305378/v1 Negative / Null Result ReportOpen accessMedicine
Toyoshima M, Toyofuku R, Shimoda S et al. · 2026 · Neuropsychopharmacology reports
Adolescence is a sensitive developmental stage in which exposure to addictive substances can produce long-lasting changes in the neural circuits that regulate reward. Nicotine and ethanol are frequently co-used among adolescents, and…
View details →DOI: 10.1002/npr2.70132 Negative / Null Result ReportOpen accessMedicine
McVige J, Masset L, Mechtler L et al. · 2026 · Journal of child neurology
Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy,…
View details →DOI: 10.1177/08830738251369759 Negative / Null Result ReportMedicine
Ferreira HRS, Hadden AC, Champagnon J et al. · 2025 · The Science of the total environment
Despite the vital importance of wetlands globally, these habitats have increasingly received anthropogenic materials, such as plastics, which can impact the wildlife these habitats support. Despite commonly found in the nests of Eurasian…
View details →DOI: 10.1016/j.scitotenv.2025.178588 Negative / Null Result ReportOpen accessMedicine
Ohlsen SM, Pirkle SB, Yang J et al. · 2026 · JSES reviews, reports, and techniques
Background Machine learning, a subset of artificial intelligence, enables large language models (LLMs) like ChatGPT and Gemini to analyze data, learn from context, and generate responses without explicit programming. While machine learning…
View details →DOI: 10.1016/j.xrrt.2026.100715 Negative / Null Result ReportMedicine
Qiu K, Hang Y, Lv P et al. · 2025 · Translational stroke research
To evaluate whether endovascular thrombectomy (EVT) combined with best medical management (BMM) is more effective than BMM alone in treating mild stroke patients (National Institutes of Health Stroke Scale score pri ) group and the primary…
View details →DOI: 10.1007/s12975-025-01337-1 Negative / Null Result Report
Radin D · 2024 · Preprint
The consciousness-collapse interpretation of quantum mechanics was explored by testing if human observation might act like a weak quantum measurement effect in an optical interferometer. Forty-seven participants selected via a worldwide…
View details →DOI: 10.31234/osf.io/t3jxk Negative / Null Result ReportMedicine
Wu Y, Xu Y, Bi Z et al. · 2025 · Journal of oral rehabilitation
Background Previous studies have linked sleep quality to temporomandibular joint disorders (TMD), suggesting a role for snoring in this association. However, the directionality of this relationship remains a subject of debate. This…
View details →DOI: 10.1111/joor.13916 Negative / Null Result ReportOpen accessMedicine
Yepes Gómez D, Moreno-Bedoya S, Lohle-Rueda S et al. · 2026 · Frontiers in nephrology
Background Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and carries high short-term mortality despite timely antimicrobials and organ support. Adsorptive hemofilters such as the oXiris ® membrane have…
View details →DOI: 10.3389/fneph.2026.1810007 Negative / Null Result Report
Horovitz O · 2024 · Preprint
Background: /Objectives: The growing interest in nutritional psychology has sparked exploration into how eating habits impact emotional, cognitive, and physical health. The Theory of Food (ToF) posits that childhood eating patterns shape…
View details →DOI: 10.20944/preprints202409.1895.v1 Negative / Null Result Report
Kiplagat E, Ramezani M, Malla S et al. · 2024 · Preprint
This study investigated the survival and growth of Salmonella in onion extracts and bulbs. Extracts of an array of onion varieties and germplasms were used to evaluate their ability to retard or inhibit Salmonella growth and the…
View details →DOI: 10.20944/preprints202411.1124.v1 Negative / Null Result ReportMedicine
Baumeister A, Schuurmans L, Schultz J et al. · 2025 · Behaviour research and therapy
Background and aim The efficacy of internet-based interventions (IBI) for various psychiatric disorders is widely established, but little is known about the mechanisms or possible influencing factors. One of the most prominent problems in…
View details →DOI: 10.1016/j.brat.2024.104673 Negative / Null Result ReportOpen accessMedicine
Zhan S, Zhang D, Ou Y · 2026 · Frontiers in psychology
Trauma-related distress in adult women often extends beyond posttraumatic stress disorder (PTSD) to include depressive symptoms and dissociation, yet the roles of mindfulness and self-compassion across these symptom domains remain…
View details →DOI: 10.3389/fpsyg.2026.1716193 Negative / Null Result ReportMedicine
Kurimoto M, Nawashiro T, Nagakura M et al. · 2025 · The Journal of craniofacial surgery
Craniosynostosis limits normal cranial growth, significantly affecting the growth and development of children. This increase in intracranial pressure results in significant cosmetic and functional losses. This study investigated the…
View details →DOI: 10.1097/scs.0000000000010799 Negative / Null Result ReportOpen accessMedicine
Mao J, Gan Y, Tan X et al. · 2025 · International journal of women's health
Objective High basophil count levels are associated with an increased risk of gestational diabetes mellitus (GDM). We used two-sample Mendelian randomisation (MR) to explore a potential causal relationship. It also aims to offer genetic…
View details →DOI: 10.2147/ijwh.s500632 Negative / Null Result ReportOpen accessMedicine
Killer HE, Pircher A, Stekhoven DJ · 2026 · Ophthalmology and therapy
Introduction The Collaborative Normal-Tension Glaucoma Study (CNTGS) is frequently cited as evidence that a 30% reduction in intraocular pressure (IOP) slows progression in normal-tension glaucoma (NTG). This study re-examines the…
View details →DOI: 10.1007/s40123-025-01300-1 Negative / Null Result Report
Schulz KM, Chavez MC, Forrester-Fronstin Z · 2024 · Preprint
Early pubertal onset during adolescence is consistently linked with increased risk of anxiety and depression in girls. Although estradiol tends to have anxiolytic effects in adulthood, whether sensitivity to estradiol’s anxiolytic actions…
View details →DOI: 10.1101/2024.09.02.610911 