A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21733 results · page 487 of 725
Su X, Zhang L, Sun Y et al. · 2024 · Preprint
Abstract Background The diverse types and processing methods of grains intricately influence the sites and digestibility of starch digestion, thereby impacting energy utilization. This study aimed to explore the impact of grain variety and…
Nikolaeva A, Vandeputte M · 2025 · Endocrinology, diabetes & metabolism case reports
Summary Semaglutide, a GLP-1 receptor agonist (RA), is approved for the treatment of type 2 diabetes and obesity. However, its increasing off-label use, particularly for cosmetic weight loss, raises concerns considering its potential…
El Idrissi Y, El Moudden H, Belhoussaine O et al. · 2025 · Chemistry & biodiversity
This study investigates for the first time the effects of UV light exposure on the chemical composition of artisanal and cold-pressed culinary and cosmetic argan oils, as well as their quality and biological activities. We ascertained the…
Jhaj J, Woolner B, Rankin S et al. · 2025 · Shoulder & elbow
This study evaluated the outcome and recurrence rates after hydrodilatation (HD) in patients with frozen shoulder (FS), comparing the effects of injecting 25 mL or more of fluid versus lower volumes. A total of 132 shoulders (130 patients)…
Banerjee S, Berry Y, Fisher E et al. · 2025 · Neuroscience letters
Genetic leukoencephalopathy (gLE) is a white matter disorder affecting the central nervous system, causing hypomyelination, developmental delays, motor deterioration, and cognitive, visual, and hearing impairments. Its clinical variability…
Alsheekh A, Kibrik P, Marks N et al. · 2025 · Vascular
BackgroundThe minimally invasive procedures of venous ablation and iliac vein stenting are evolving treatment options for venous insufficiency. Yet, there are no studies directly comparing the outcome of these procedures. We performed a…
Altamirano F, Gonzalez E, Oke I · 2024 · Digital journal of ophthalmology : DJO
A healthy 4-year-old boy referred for evaluation of an abnormal red reflex in the left eye was noted, on fundus examination, to have extensive white, striated lesions surrounding the optic nerve that involved the superior and inferior…
Wang S, Huang H, Huang F et al. · 2023 · Preprint
Background: To explore a visual model for predicting the prognosis of older patients with non-metastatic nasopharyngeal carcinoma (NPC) and analyze survivals in different patient groups during intensity-modulated radiotherapy (IMRT).…
Hata Y, Iida O, Torii S et al. · 2026 · European heart journal. Case reports
Background The long-term vascular response to paclitaxel-eluting stents (PESs) in infrapopliteal (IP) lesions remains histologically uncharacterized. Case summary A 78-year-old woman with chronic limb-threatening ischaemia underwent…
Agergaard J, Gunst JD, Schiøttz-Christensen B et al. · 2023 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Knowledge is limited on how changing SARS-CoV-2 variants may translate into different characteristics and affect the prognosis of patients with long COVID, especially following Omicron variants. We compared long-term prognosis…
Pyzer AR, Dillon LW, Sharon E et al. · 2025 · Blood advances
Abstract We conducted a multicenter, open-label, randomized phase 2 study to assess the efficacy of nivolumab (Nivo) as maintenance therapy for patients with acute myeloid leukemia (AML) in first complete remission (CR) or CR with…
Narayanan A, Khashram M, Fisher JP · 2024 · Preprint
Abstract High stress may diminish a surgeon’s performance in the operating room (OR). Music is perceived to reduce stress in the OR, however the psycho-physiological effects of music on intra-operative stress in inexperienced and…
Pascha MN, Ballegeer M, van Haperen R et al. · 2024 · Preprint
Antibodies targeting hemagglutinin and neuraminidase (NA) are key components of the adaptive immune response against influenza A virus (IAV). However, antigenic drift allows the virus to escape inhibition by such antibodies. In this study,…
Markou M, Katsouda A, Papaioannou V et al. · 2024 · Phytotherapy research : PTR
Obesity is a major source of morbidity worldwide with more than 2 billion adults being overweight or obese. The incidence of obesity has tripled in the last 50 years, leading to an increased risk for a variety of noncommunicable diseases.…
Carroll AM, Pruitt DT, Riley JR et al. · 2024 · Scientific reports
Learning new skills requires neuroplasticity. Vagus nerve stimulation (VNS) during sensory and motor events can increase neuroplasticity in networks related to these events and might therefore serve to facilitate learning on sensory and…
Langley C, Plakotaris E, Rogers NE · 2025 · Case reports in dermatology
Introduction Lichen planopilaris (LPP) is a well-known cicatricial alopecia with a frontal fibrosing variant. LPP has a prevalence rate of 13.4 per 100,000 persons. It is understood that LPP favors the female populations. What is not…
Panca M, Serfaty M, Satchell J et al. · 2026 · BJPsych open
Background Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims This paper aims to evaluate the cost-effectiveness of a victim improvement package (VIP) for the reduction…
Fernandes Cabral DT, Fernández-de Thomas RJ, Alattar A et al. · 2024 · Neurosurgical focus: Video
Odontoid pannus is an abnormal collection of degenerative or inflammatory tissue on the C1-dens joint that can result in severe spinal cord compression myelopathy. Treatment options vary depending on severity and etiology. In cases of…
Story BD, Thomasy SM, Randolph MW et al. · 2024 · Frontiers in veterinary science
Sjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population. The hallmark…
Sood M, Hegde V, Prabhu N et al. · 2026 · Journal of Indian Prosthodontic Society
Aim This study aimed to assess the shear bond strength between three-dimensional (3D)-printed acrylic denture base resin and 3D-printed teeth with and without ridge lap surface modifications. Materials and methods The investigation…
Bhatia A, Chen Z, Zhang Y et al. · 2026 · Cancer
Background Ataxia telangiectasia Rad3-related (ATR) protein kinase regulates DNA damage response and is essential for tumor cell survival. Preclinically, ATR inhibition can sensitize tumor cells to radiation and chemotherapy. The authors…
Li W, Shi M, Zhou P et al. · 2024 · Preprint
Background: The outcome of extramedullary infiltration (EMI) in pediatric acute myeloid leukemia (AML) is controversial, and little is known about the implications of stem cell transplantation (SCT) and gemtuzumab ozogamicin (GO) treatment…
Gass R, Plachi F, Silva FOB et al. · 2025 · Respiratory physiology & neurobiology
Excess exercise ventilation (high ventilation (V̇ E )/carbon dioxide output (V̇CO 2 )) contributes significantly to dyspnea and exercise intolerance since the earlier stages of chronic obstructive pulmonary disease (COPD). A selective…
Karajannis MA, Onar-Thomas A, Lin T et al. · 2025 · Neuro-oncology
Background The outcome for pediatric patients with high-grade glioma (HGG) remains poor. Veliparib, a potent oral poly(adenosine diphosphate-ribose) polymerase (PARP) 1/2 inhibitor, enhances the activity of radiotherapy and DNA-damaging…
Pickard S, Speach D, Hauber K et al. · 2026 · Interventional pain medicine
Background Low back injury is one of the leading causes of work-related injuries, disability, and lost productivity. Patients with lumbar radiculopathy are a subgroup of patients within work related low back injury. To our knowledge, there…
Luo JY, Xiang J, Hong XL et al. · 2026 · The American journal of case reports
BACKGROUND Epidermal growth factor receptor (EGFR) is a key driver gene in non-small-cell lung cancer (NSCLC), and EGFR tyrosine kinase inhibitors (TKIs) are the standard treatment for classical mutations, including exon 19 deletion and…
Raj AK, Pedersen SJ, Mainsbridge C et al. · 2024 · Ergonomics
Prolonged sitting is postulated to influence musculoskeletal performance (cervical flexor endurance, balance, and agility), discomfort and alter cervical spine angles during work-based computer use. Stair climbing breaks may be a great…
Li N, Wu C, Cao P et al. · 2024 · Access microbiology
Background Rhodococcus equi is one of the most important causes of zoonotic infections from grazing animals. It poses a particular risk to immunocompromised individuals, including those who are undergoing long-term immunosuppressive…
Zhang Q, Yan Y, Li J et al. · 2023 · Preprint
Objectives: To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) can improve pregnancy and neonatal outcomes for patients with limited good-quality embryos. Design: Retrospective cohort study. Setting: University…
Liu H, Hu Z, Song Q et al. · 2025 · JAMA network open
Importance Evidence from everyday dining situations regarding the effects of traffic light labels (TLLs) on dietary improvement remains inconsistent. Objective To evaluate the effects of TLLs on dietary consumption and choices in cafeteria…