A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21328 results · page 485 of 711
SAHIN D · 2026 · Preprint
Abstract This study examines the motivational factors shaping ısers’ continuance intention toward generative artificial intelligence (GAI) by integrating the Uses and Gratifications theory (U&G) with the Unified Theory of Acceptance and…
Layton KL, Edwards TL, Foster TM · 2026 · Journal of the experimental analysis of behavior
Translational research investigating traditional differential reinforcement of alternative behavior (DRA) suggests that such procedures increase the persistence of target behavior relative to when the alternative behavior is first…
Betz M · 2026 · Preprint
Abstract This study estimates the geographic variation in the fertility effects of state-level abortion bans on birth rates across urban, micropolitan, and rural areas. Using restricted county-level birth data from the National Center for…
Setyawan H, Andhika Akbar Rahma R, Nur Kusuma N et al. · 2026 · Preprint
Background: Workplace fatigue is a significant factor that can impact worker safety and productivity, particularly in industrial environments with high levels of noise exposure. Various types of hearing protection, such as earmuffs and…
Bair H · 2026 · NPJ digital medicine
Li et al. report that clinician last authorship is associated with greater "impact" in AI deployment trials. This commentary argues that current evidence is insufficient to attribute this to clinical leadership per se. Concerns include…
Li H, Meng W, Xiao H et al. · 2025 · BMC plant biology
BACKGROUND: Elevated temperature and enhanced ultraviolet B (UV-B) radiation are two major global climate change issues of concern today, but their effects on high-elevation rice paddy ecosystems are of limited understanding. A Two-year…
Alwadani B · 2026 · Healthcare (Basel, Switzerland)
Purpose Variation in knee MRI diagnostic yield is often interpreted as reflecting imaging effectiveness. However, in real-world healthcare systems, diagnostic yield may instead be driven by referral behavior and patient selection.…
Bahadır-Varol A, Solgun B, Küreli G et al. · 2026 · Molecular neurobiology
Acute stress and inflammatory mediators are linked to stress-related mental disorders, yet sex-specific differences in the molecular pathways connecting them remain poorly understood. Male and female C57BL/6 mice underwent predator stress…
Artyszak A, Gozdowski D, Litwińczuk-Bis M · 2026 · Plants (Basel, Switzerland)
In 2017-2019, in a field experiment in Sahryń, Poland (50°40'42″ N, 23°47'35″ E), the effect of foliar application of various forms of silicon (calcium silicate-CS, sodium metasilicate-SM, and micronized silica-MS) and the timing of their…
Seda Beyhan Sağmen, Sevda Cömert, Nesrin Kıral et al. · 2019 · Southern Clinics of Istanbul Eurasia
INTRODUCTION[|]Seasonal and weather changes may affect the development of pulmonary embolism. The effects of seasonal and meteorological factors on mortality are controversial. We aimed to investigate the effects of seasons and meteorological data on patients with a low and high pulmonary embolism severity index and those with 30-day mortality. [¤]METHODS[|]Pulmonary embolism cases were included in our study. Daily pressure, humidity, temperature, and wind values were taken from the general online information by the Directorate of Meteorology. All cases were divided into the low-risk and high-
Gonçalo Costa, Joana Delgado-Silva, Eric Monteiro et al. · 2022 · Revista Portuguesa de Cardiologia
Aims and objectives: Vitamin D deficiency is a common finding and there is a suggested association with hypertension. Resistant hypertension is a clinical problem observed in 5–30% of hypertensive patients. Renal denervation (RDN) has been used for patients with resistant hypertension and has proven to lower blood pressure. Our primary goal was to assess the vitamin D serum concentration as a predictor of blood pressure response to RDN in highly selected patients. Methods: This prospective, nonrandomized, single-center study included 24 patients treated with RDN. Based on their one-year respon
Maksim S. Maramygin, Natalya B. Boldyreva, Lyudmila G. Reshetnikova · 2025 · Управленец
In the new economic reality, air quality protection behaviour of companies remains a burning issue shifting the em phasis towards saving human life and health. The article explores the relationship between the air quality protection behav iour of public companies and stock returns in different economic sectors. The research methodology is based on environmental management theory, financial management theory, and stakeholder theory. The analytical procedures performed on the data involved cross-sectoral economic analysis and econometric analysis. Empirical data are retrieved from the Federal St
Swati Dogra , Altaf Hussain Mir , Suhail Sidiq et al. · 2025 · Asian Journal of Medical Sciences
Background: Acute post-thoracotomy pain (APTP) is severe and can lead to various respiratory complications if left untreated. Epidural (Ep) analgesia is the gold standard for APTP relief. Aims and Objectives: The aims and objectives of this study were to study the impact of low-dose oral pregabalin 75 mg on APTP. Materials and Methods: 100 patients were randomized into two groups (Group P and C). The Group P, study group received pregabalin 75 mg per oral preoperatively and for 2 days postoperatively. Group C received no medication. All the patients received thoracic Ep as a standard practice.
JI Liyue, QIU Xiaonan, WANG Xijuan et al. · 2025 · Pifu-xingbing zhenliaoxue zazhi
[Objective] To evaluate the clinical efficacy and safety of intralesional injection of heparin sodium versus carbon dioxide (CO2) laser ablation in the treatment of xanthelasma palpebrarum. [Methods] A total of 38 patients with Grade Ⅰ-Ⅲ xanthelasma and normal blood lipid levels were retrospectively enrolled, and divided into two groups based on the treatment modality: the heparin sodium group (n=20) treated with intralesional injection of heparin sodium and the CO2 laser group (n=18) treated with CO2 laser ablation. The primary and secondary outcomes were compared between the two groups, incl
José Ailton Oliveira Carneiro, Taiza Elaine Grespan Santos-Pontelli, José Fernando Colafêmina et al. · 2013 · Brazilian Journal of Otorhinolaryngology
Para manter o equilíbrio postural, algumas estratégias posturais são normalmente usadas. OBJETIVO: Avaliar as estratégias posturais de jovens e idosos em diferentes condições sensoriais usando um sistema de sensores eletromagnéticos tridimensionais posicionados na primeira vértebra torácica e região sacral. Também reportamos valores de oscilação postural dos jovens e idosos. MÉTODO: Estudo transversal observacional. Participaram do estudo 25 jovens e 16 idosas. O equipamento PolhemusTM com dois sensores foi usado para avaliar os parâmetros de oscilação postural (deslocamento máximo, velocidade
Kluger N · 2026 · European journal of epidemiology
The recent Swedish study by Rietz Liljedahl et al. examining melanoma riskamong tattooed individuals has prompted critical discussion regarding a potential causal linkbetween tattoos and melanoma. While concerns persist that tattoo…
Hak Jun Kim, Eui Dong Yeo, Im Joo Rhyu et al. · 2017 · BMC Musculoskeletal Disorders
Abstract Background Malalignment of the ankle joint has been found after trauma, by neurological disorders, genetic predisposition and other unidentified factors, and results in asymmetrical joint loading. For a medial open wedge supramalleolar osteotomy(SMO), there are some debates as to whether concurrent fibular osteotomy should be performed. We assessed the changes in motion of ankle joint and plantar pressure after supramalleolar osteotomy without fibular osteotomy. Methods Ten lower leg specimens below the knee were prepared from fresh-frozen human cadavers. They were harvested from five
Uzair Ahmad, Babar Ali, Seema Gul et al. · 2025 · Journal Riphah College of Rehabilitation Sciences
Background: Regular physical activity has a positive impact on brain function, improves perception, and significantly influences academic achievement. Objective: This study aimed to determine the association of physical activity, motor skills, and academic performance in high school students in Hayatabad, Peshawar. Methodology: A total of 349 students were recruited using stratified random sampling from both public and private high schools within the Hayatabad region, Peshawar, Pakistan from December 2020 to May 2021. Only students in 9th and 10th grades from public and private schools who met
Rudra Paul, Arijit Ghosh, Nilanjan Sengupta et al. · 2022 · National Journal of Physiology, Pharmacy and Pharmacology
Background: Type 2 diabetes mellitus (DM) is mainly due to multifactorial of which insulin resistance and deficiency in the incretion are two important pathophysiological factors. Vildagliptin, an oral hypoglycemic agent, acts by inhibiting dipeptidyl peptidase-4 enzyme, often uses as a first line drug along with metformin to enhance outcome. Aim and Objective: The aim of this study was to compare the effectiveness and safety of vildagliptin 50 mg twice daily dose with vildagliptin 100 mg sustained release tablet (SR) once daily in Type 2 DM patients and uncontrolled with metformin monotherapy
Davidović Lazar B., Kuzmanović Ilija B., Kostić Dušan M. et al. · 2002 · Srpski Arhiv za Celokupno Lekarstvo
The infection of the previously implanted vascular graft at the groin, is associated with great mortality and morbidity rate [1]. The authors present a retrospective study in which they analyzed management of infected vascular prostheses at the groin, using obturator bypass in 26 cases, and "lateral" bypass in 15 cases. The indications for obturator bypass reconstructions included: 20 infections of aorto-femoral grafts, two infected pse udoaneurysms in the groin after RTA of the superficial femoral artery, and 4 infections of iliac-femoral grafts. The indications for lateral bypass reconstruct
Zihao Qiu, Siyu Chen, Zixin Feng et al. · 2025 · Frontiers in Physics
Futures, as significant financial derivatives, play a crucial role in financial markets by fulfilling price discovery functions and providing efficient risk hedging tools. Against the backdrop of geopolitical conflicts, market risk emerges not only from external shocks and random fluctuations but also from strategic interactions among diverse participants including hedgers, speculators, arbitrageurs, and regulators. This study integrates traditional VaR theory with machine learning methods to systematically examine risk characteristics and transmission mechanisms in the sugar futures market un
NING Li, ZHANG Yanyan, ZENG Jinfeng et al. · 2026 · Zhongguo shuxue zazhi
[Objective] To statistically analyze the association between blood donation intervals and the incidence of adverse reactions to blood donation based on blood donor data from Shenzhen. [Methods] Basic data and records of adverse reactions to blood donation among voluntary whole blood donors in Shenzhen from January 2017 to June 2025 were extracted. A total of 795 404 whole blood donations were recorded, including 502 743 from males and 292 661 from females, with 1 088 and 751 cases of adverse reactions, respectively. Analyses were performed using R software, including restricted cubic spline (R
Sowinska N, Ochota M, Partyka A et al. · 2026 · Animal reproduction science
The domestic cat (Felis catus) provides a valuable model for developing assisted reproductive technologies (ART) that can be applied to the conservation of endangered wild felids. A major limitation in the application of ART is the…
Alberta Simona Tinu, Doina Lucia Ghergic, Mirel Stoian et al. · 2018 · Romanian Journal of Stomatology
Objectives. We performed a retrospective observational analytical study to determine the incidence of complications in the oral cavity in a group of patients diagnosed with diabetes mellitus. Material and method. We have studied 68 diabetic patients, who have been referred to dental practices seeking specialized treatment. Patient data sheets were centralized, categorized, and statistically processed with IBM SPSS Statistics 22 and Microsoft Excel 2010 depending on: sex of patients, age, type of diabetes, time elapsed from diagnosis of diabetes, the environment of origin of the patients, the l
Yunsur Çevik, Fatma Nur Karaarslan, Şeref Kerem Çorbacıoğlu et al. · 2022 · Eurasian Journal of Emergency Medicine
Aim:The aim of this study was to examine the relationship between immature granulocyte (IG) counts and the severity of the disease and to evaluate the effectiveness of IG in predicting the poor outcomes in polymerase chain reaction-confirmed Coronavirus disease-2019 (COVID-19) cases.Materials and Methods:The study was conducted prospectively and observationally at the emergency department. Patients were divided into three groups according to the clinical severity indicators such as mild, moderate and severe. The IG level was measured from the whole blood samples taken at the admission to the e
Rasa Liutkevičienė, Ramunė Sungailienė, Alvita Vilkevičiūtė et al. · 2017 · Acta Medica Lituanica
Background. Age-related macular degeneration (AMD) is the most common cause of irreversible visual loss in industrialized countries. Early symptoms of AMD include drusen and changes in retinal pigment epithelium. However, the etiology of AMD and drusen formation is not fully understood. Recent studies suggest that CYP2C8-related metabolic processes might play an important role in the development of AMD. The aim of our study is to investigate CYP2C8 rs10509681 and CYP2C8 rs11572080 genotype frequencies in patients with early AMD and to compare them with healthy controls. Materials and Methods.
Hao Lu, Shikuan Li, Chengzhi Wang et al. · 2025 · BMC Gastroenterology
Abstract Objective To investigate the impact of peritoneal lavage on the incidence of intra-abdominal abscess (IAA) after laparoscopic appendectomy (LA) in adults with perforated appendicitis. Methods Clinical data from adult patients intraoperatively diagnosed with perforated appendicitis and undergoing LA at the Affiliated Hospital of Qingdao University between January 2020 and January 2025 were retrospectively analyzed. Patients were divided into a no-peritoneal lavage group and a peritoneal lavage group based on whether peritoneal lavage was performed. A total of 128 patients were included
Maria Aparecida A.O. Serra, PhD, Arlene T. Medeiros, RN, Mateus D. Torres, RN et al. · 2021 · Journal of Taibah University Medical Sciences
الملخص: أهداف البحث: الأعراض الهضمية هي الشكاوى الأكثر شيوعا من قبل المرضى الذين يسعون للحصول على خدمات الرعاية الصحية الأولية. تهدف هذه الدراسة إلى تحديد أعراض الجهاز الهضمي وتحديد ارتباطها بنتائج التنظير المعوي العلوي لدى المرضى الذين عولجوا في مركز التنظير العام في شمال شرق البرازيل. طرق البحث: أجرينا دراسة مقطعية باستخدام بيانات ٧٥١ مريضا يعانون من أعراض الجهاز الهضمي ولديهم حاجة للتنظير المعوي العلوي. حددنا الارتباط بين هذه المتغيرات من خلال اختبار فيشر الدقيق وحسبنا نسبة الاحتمالات. النتائج: أظهرت النتائج أن ٨٣٪ من المرضى يعانون من آلام شرسوفية، ٧٢.٦٪ من الامتلاء بعد الأكل، و٧٢.٣٪ من حرق
Imran Majid, Gousia Sheikh, Farhath Kanth et al. · 2016 · Indian Journal of Dermatology
Background: The incidence of recurrent tinea infections after oral terbinafine therapy is on the rise. Aim: This study aims to identify the appearance of incomplete cure and relapse after 2-week oral terbinafine therapy in tinea corporis and/or tinea cruris. Materials and Methods: A total of 100 consecutive patients clinically and mycologically diagnosed to have tinea corporis and/or tinea cruris were included in the study. The enrolled patients were administered oral terbinafine 250 mg once daily for 2 weeks. All clinically cured patients were then followed up for 12 weeks to look for any rel
Damkoeng Purnindu · 2023 · Siriraj Medical Journal
Dissection of one-half of adult pelvis in 197 Thai and 44 Chinese cadavers disclosed that the obturator artery arose from the internal iliac and umbilical arteries in 34.9%, from the inferior gluteal artery in 10.4%, from the internal pudendal artery in 8.7%, from the superior gluteal - inferior gluteal trunk in 4.2%, from the inferior gluteal - internal pudendal trunk in 9.1%, from the inferior epigastric artery in 12.0%, from the external iliac artery in 1.2%, and from the superior gluteal and the inferior epigastric arteries in 0.4%. There were no statistically significant differences of fi