Negative / Null Result ReportOpen accessMedicine
Jaafari Z, Hassanzadeh J, Sayadi M et al. · 2026 · Health science reports
Background and aims The variation in the incidence of type 2 diabetes mellitus (T2DM) in different countries is associated with various factors. This study aimed to examine the factors linked to the difference in the incidence of T2DM…
View details →DOI: 10.1002/hsr2.72569 Negative / Null Result ReportMedicine
Sabri H, Baniameri S, Kataria P et al. · 2026 · Journal of periodontology
Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α-Klotho, an anti-aging protein with anti-inflammatory properties, has been associated with…
View details →DOI: 10.1002/jper.70080 Negative / Null Result ReportOpen accessMedicine
Hendricks S, Huynh A, Burns DT et al. · 2026 · AIDS research and treatment
Purpose To determine whether sociodemographic factors, including residence in rural/frontier versus urban settings, are associated with differences in HIV viral suppression rates among people living with HIV in Wyoming with one or more…
View details →DOI: 10.1155/arat/7353282 Negative / Null Result ReportOpen accessMedicine
Xiong Y, Huang J, Wu Y et al. · 2026 · Renal failure
Physical activity (PA) is of great importance for peritoneal dialysis (PD) patients with sarcopenia. However, the optimal PA dose for sarcopenia in PD patients remains unclear. This study adopted a cross-sectional design and enrolled PD…
View details →DOI: 10.1080/0886022x.2026.2686047 Negative / Null Result ReportMedicine
Luo M, Wang Y, Wang Y et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Objective The optimal interpregnancy interval (IPI) for preventing hypertensive disorders of pregnancy (HDP) remains unclear, and whether this association is modified by maternal baseline characteristics has not been well established. This…
View details →DOI: 10.1080/14767058.2026.2661436 Negative / Null Result ReportMedicine
Revilla-León M, Gómez-Polo M, Barmak AB et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem As experience with intraoral scanners (IOSs) and scientific evidence has grown, factors compromising IOS accuracy have been identified. Limited interdental space between tooth preparations lead to the bridge scanning…
View details →DOI: 10.1016/j.prosdent.2026.04.031 Failed Experiment ReportMedicine
Steinharter JA, Chou J, Ilagan CH et al. · 2026 · Journal of the American College of Surgeons
Background An adequate future liver remnant volume (FLRV%) reduces the risk of posthepatectomy liver failure (PHLF). This study evaluates (1) the association of FLRV% with grade 4/5 morbidity and (2) the safe FLRV% threshold for PHLF- and…
View details →DOI: 10.1097/xcs.0000000000001801 Negative / Null Result ReportMedicine
Seale L, Bates N, Tumin D et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To examine the association between age at menarche and polycystic ovary syndrome (PCOS) diagnosis among US women aged 20-49 years. Study design Our retrospective cross-sectional analysis used data from the 2022-2023 National…
View details →DOI: 10.1016/j.ejogrb.2026.115140 Negative / Null Result ReportOpen accessMedicine
Wang X, Zhang R, Chai W et al. · 2026 · Medicine
The incidence of IgA nephropathy (IgAN) is increasing, and some observational studies reported the potential correlation of polycystic ovary syndrome (PCOS) with the risk of IgAN. We performed a bidirectional Mendelian randomization…
View details →DOI: 10.1097/md.0000000000048704 Negative / Null Result ReportMedicine
Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…
View details →DOI: 10.1016/j.jisako.2026.101134 Negative / Null Result ReportOpen accessMedicine
Bax EA, Colyn W, Bellemans J et al. · 2026 · Osteoarthritis and cartilage open
Objectives This study investigated the association between alpha angles of the hip and tibial genu varum in a healthy population with equal male-to-female distribution. It also examined sex-based differences, explored the impact of sports…
View details →DOI: 10.1016/j.ocarto.2026.100803 Negative / Null Result Report
GUILLEN SANCHEZ JS, Saenz Tolay M, Cabanillas Chirinos L et al. · 2026 · Preprint
Background: The rising consumption of ultra-processed foods (UPFs) is a global concern, given their poor nutritional quality and the presence of multiple additives that may pose health risks when consumed in excess. Young populations are…
View details →DOI: 10.12688/f1000research.166729.2 Negative / Null Result ReportOpen accessMedicine
Motoji Y, Kitamura T, Naito N et al. · 2026 · Interdisciplinary cardiovascular and thoracic surgery
Objectives This study aimed to investigate changes in haematoma thickness (HT) and the maximum ascending aortic diameter (MAD) early after onset and their association with in-hospital disease progression in type A intramural haematoma…
View details →DOI: 10.1093/icvts/ivag146 Negative / Null Result ReportOpen accessMedicine
Mannen R, Maeda K, Inoue T et al. · 2026 · Journal of frailty, sarcopenia and falls
Objectives Osteosarcopenia is characterized by the coexistence of sarcopenia and osteoporosis. This comorbid condition is thought to negatively affect functional outcomes. In this study, we investigated the negative impact of…
View details →DOI: 10.22540/jfsf-11-118 Negative / Null Result ReportMedicine
Othus M, Truong TG, Sharon E et al. · 2026 · JCO oncology practice
Purpose Multiple reports have suggested that receiving immunotherapy infusions earlier in the day is associated with improved outcomes, including longer overall survival (OS) and lower toxicity rates. However, the definition of early…
View details →DOI: 10.1200/op-25-01413 Negative / Null Result Report
Molla HT, Gashu D, Chowanadisai W et al. · 2026 · Preprint
Background: Etiologies of neural tube defects (NTDs) are multifactorial. Genetic, epigenetic and environmental factors may contribute to their reported variation in prevalence across the globe. Ethiopia has among the highest reported NTD…
View details →DOI: 10.20944/preprints202603.2176.v1 Negative / Null Result ReportMedicine
Tabeta A, Tsutsumi Y, Hoshi H et al. · 2026 · BMC surgery
Background Perforated peptic ulcer is a critical emergency disease requiring surgery, and postoperative intra-abdominal abscess (IAA), an organ/space surgical site infection (SSI), is a common complication. Intraoperative irrigation is a…
View details →DOI: 10.1186/s12893-026-03813-3 Negative / Null Result ReportMedicine
Hsu JZ, Gu K, Nguyen B et al. · 2026 · The Annals of otology, rhinology, and laryngology
Objective Estrogen has been found to impact cochlear blood flow and auditory function, but epidemiological studies on menopause and hearing are inconsistent. This study investigates the associations of menopause, its age at onset,…
View details →DOI: 10.1177/00034894261435259 Negative / Null Result Report
Nandurkar A · 2026 · Preprint
Abstract Background Hearing loss in adults is a leading problem worldwide. Provision of the whole spectrum of aural rehabilitation (AR) services to adults with acquired hearing loss has been acknowledged as a global challenge, due to…
View details →DOI: 10.21203/rs.3.rs-9352289/v1 Negative / Null Result Report
Al-Mujahid M, shomais A, Sinan Y et al. · 2026 · Preprint
Abstract Background Health-related quality of life (HRQoL) is a crucial patient-centered outcome in the management of chronic diseases, particularly cardiovascular disease (CVD). Objective To assess the health-related quality of life and…
View details →DOI: 10.21203/rs.3.rs-9202220/v1 Negative / Null Result ReportMedicine
Keel E, Kalimeris S, Adams M et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Background Infants born before 32 weeks of gestation are at high risk of developing intraventricular hemorrhage (IVH), which is associated with significant mortality and morbidity as well as long-term neurodevelopmental impairment. There…
View details →DOI: 10.1080/14767058.2026.2650951 Negative / Null Result ReportMedicine
Maharjan U, Kauppila JH · 2026 · Surgical oncology
Background Previous studies on hospital volume of gastrectomy and mortality in gastric cancer are conflicting, with some suggesting improved short-term outcomes in higher volume hospitals and fewer studies demonstrating consistent findings…
View details →DOI: 10.1016/j.suronc.2026.102415 Negative / Null Result ReportOpen accessMedicine
Molla HT, Gashu D, Stoecker B et al. · 2026 · Genes
Background Etiologies of neural tube defects (NTDs) are multifactorial. Genetic, epigenetic and environmental factors may contribute to their reported variation in prevalence across the globe. Ethiopia has among the highest reported NTD…
View details →DOI: 10.3390/genes17040478 Negative / Null Result ReportMedicine
Cheng V, Sayre EC, Amiri N et al. · 2026 · Journal of autoimmunity
Objectives While targeted synthetic disease-modifying antirheumatic drugs (tsDMARDs) have advanced autoimmune disease management, the paucity of perinatal safety data limits evidence-based decision-making in pregnancy. We aimed to…
View details →DOI: 10.1016/j.jaut.2026.103538 Negative / Null Result ReportOpen accessMedicine
Berto LG, da Silva CL, Durante MV et al. · 2026 · Pediatric surgery international
Objective Acute appendicitis is the leading cause of abdominal surgery. This study evaluated outcomes of transumbilical single-incision laparoscopic appendectomy (TSILA) compared with conventional laparoscopy and open surgery. Methods A…
View details →DOI: 10.1007/s00383-026-06448-w Negative / Null Result ReportOpen accessMedicine
Alogaili MH, Hussein ZA, Alsallami AA et al. · 2026 · BMC medical education
Background Time management involves using time efficiently to complete specific tasks and the grade point average (GPA) is a summary statistic that represents students' average academic performance over a specific period. Both the…
View details →DOI: 10.1186/s12909-026-08813-8 Negative / Null Result ReportMedicine
Ji J, Sun CL, Dale W et al. · 2026 · GeroScience
Among older adults with early breast cancer, the risk of chemotoxicity can vary widely despite similar chronological age. Here, we evaluated whether epigenetic indicators of biological age can stratify the risk of chemotoxicity in this…
View details →DOI: 10.1007/s11357-026-02298-5 Negative / Null Result ReportMedicine
Götz N, Völkerer A, Hofer H et al. · 2026 · Scandinavian journal of gastroenterology
Background Barrett's esophagus (BE) is a premalignant condition associated with gastroesophageal reflux disease (GERD) and an increased risk of esophageal adenocarcinoma (EAC). While Helicobacter pylori ( H. pylori ) has been proposed as a…
View details →DOI: 10.1080/00365521.2026.2632058 Negative / Null Result ReportMedicine
Benvenuti L, Digennaro V, Colangelo A et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Purpose The influence of polyethylene (PE) insert thickness on long-term implant survival after total knee arthroplasty (TKA) remains controversial. Thicker PE inserts are generally reserved for cases in which adequate ligament balance…
View details →DOI: 10.1007/s00590-026-04743-9 Negative / Null Result ReportMedicine
Garcia-Ruiz MP, Torres-Bautista RM, Lopez-Franco MD et al. · 2026 · Journal of clinical medicine
Objectives: The general objective of the study was to analyze the influence of sociodemographic factors and care and hygiene practices on the appearance of Incontinence-Associated Dermatitis (IAD). The specific objectives were to identify…
View details →DOI: 10.3390/jcm15051752 