Memory Impairment and Plasma BDNF Correlates of the BDNF Val66Met Polymorphism in Patients With Bipolar II Disorder
Yun-Hsuan Chang; Yun-Hsuan Chang; Yun-Hsuan Chang; Tzu-Yun Wang; Tzu-Yun Wang; Sheng-Yu Lee; Sheng-Yu Lee; Sheng-Yu Lee · 2018 · Frontiers in Genetics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Studies suggest that a functional polymorphism of brain-derived neurotrophic factor (BDNF), polymorphism BDNF Val66Met affects cognitive functions, however, the effect is unclear in bipolar II (BD-II) disorder. We used the Wechsler Memory Scale-third edition (WMS-III), the presence of the BDNF Val66Met polymorphism, and plasma concentrations of BDNF to investigate the association between memory impairment and BDNF in BD-II disorder. We assessed the memory functions of 228 BD-II patients and 135 healthy controls (HCs). BD-II patients had significantly lower scores on five of the eight WMS-III s
Abstract by Yun-Hsuan Chang; Yun-Hsuan Chang; Yun-Hsuan Chang; Tzu-Yun Wang; Tzu-Yun Wang; Sheng-Yu Lee; Sheng-Yu Lee; Sheng-Yu Lee, Frontiers in Genetics (2018) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
The Impact of the D727e Polymorphism has no Significant Role in Multi Nodular Goiter
Negative / Null Result ReportGenetic polymorphisms at the leptin receptor gene in three beef cattle breeds
Negative / Null Result ReportIs there are relationship between polymorphisms TSHR gene frequencies and genetic ancestry markers in patients with Primary Congenital Hypothyroidism?
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.3389/fgene.2018.00583