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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21318 results · page 420 of 711

Negative / Null Result ReportOpen accessAnimal culture

Effect of altered microclimate on alleviating heat stress in sheep

RAVIKANTH JETTY, S SREEDHAR, CH VENKATA SESHAIAH2 et al. · 2025 · Indian Journal of Animal Sciences

The present research was conducted to study the effect of fan and foggers on Temperature Humidity Index (THI) and physiological responses in Nellore brown sheep during summer. Twenty ewes of age 3-5 years from sheep unit of Livestock Farm Complex of NTR college of Veterinary Sciences, Gannavaram were divided into 2 groups of each 10 ewes each in a completely randomized design on the basis of body weight. The animals in the group-I were considered as control whereas the animals in the group-II were equipped with fan and foggers for modification of microclimate in the shed. Data on temperature-h

View details →DOI: 10.56093/ijans.v95i3.146026
Negative / Null Result ReportOpen accessScience (General)

Evaluation of genetic correlation with fluoroquinolones resistance in rifampicin-resistant Mycobacterium tuberculosis isolates

Chong Teng, Ling Li, Dan Su et al. · 2024 · Heliyon

Objective: To detect levofloxacin (LFX) and moxifloxacin (MFX) resistance among rifampicin-resistant tuberculosis (RR-TB) isolates, and predict the resistance level based on specific mutations in gyrA and gyrB genes. Methods: A total of 686 RR-TB isolates were collected from Chinese Drug Resistance Surveillance Program from 2013 to 2020. The minimum inhibitory concentrations (MICs) of 12 anti-TB drugs were acquired using the broth microdilution method, followed by whole genome sequencing (WGS) analysis. Results: Among the 686 RR isolates, the most prevalent resistance was to isoniazid (80.5 %)

View details →DOI: 10.1016/j.heliyon.2024.e31959
Negative / Null Result ReportOpen accessManagement. Industrial management

Management Performance Evaluation for Academic Public Libraries

Majid Aligholizadeh, Mohammad Akbari, Fatemeh Zandian et al. · 2014 · مطالعات مدیریت راهبردی

The aim of Paper is to analyze and evaluate the performance of management in Tehran academic public libraries based on the model of EFQM that tries to identify the weak points and strong points of the management, plan for the improvement of strong points and resolve the weak points to get to a more competent and desirable situation in the society so that they can be able to improve their services and satisfy the needs of their members and customers more than ever. The methodology used to conduct this research is a survey and to collect the data a 72 item questionnaire of European Foundation fo

Negative / Null Result ReportOpen accessDentistry

Evaluation the effect of sesame oil on root dentin microhardness after application of chloroform and orange oil as gutta percha solvents (an in- vitro study).

Nsar Muhyaddin Aziz · 2022 · Erbil Dental Journal

Background and objectives: Gutta percha solvents like chloroform and orange oil have different effects on physio-chemical properties like the microhardness of root dentine. Aim: Effects of sesame oil on the micro hardness of root dentin after using chloroform and orange oil as guttapercha solvents. Methods: Twenty three extracted single rooted both upper and lower premolars were used crown separated from the root from the cement enamel junction ,remaining roots longitudinally sectioned from buccolingual direction each piece of roots mounted in cold cure acrylic resin and dentin surface of the

Negative / Null Result ReportOpen accessAgriculture

The probiotic effects of dietary inactive yeast Saccharomyces cerevisiae var. ellipsoideus on growth factors, survival, body composition and intestinal microbiota of Beluga juvenile (Huso huso)

S.H. Hoseinifar email ; A.R. Mirvaghefi; B. Mojazi Amiri; H.A. Khoshbavar Rostami; M. Poor Amini; K. Darvish Bastami · 2011 · ‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān

The probiotic effects of inactive yeast, Saccharomyces cerevisiae var. ellipsoideus was studied on growth performance, survival and intestinal microbiota of beluga juveniles (Huso huso). The study was done in complete randomize design that included feeding of beluga juveniles with diets supplemented with 0 (control), 1, 2 and 5% yeast (4 treatments with 3 replicates). Beluga juveniles (11.40±0.56g) were randomly allocated in 12 oval tanks at a density of 35 fish per tank and triplicate group were fed with experimental diets. At the end of the trial, growth factors (final weight, weight gain,

Negative / Null Result ReportOpen accessMedicine (General)

Effect of Needle Tip Position on Contrast Media Dispersion Pattern in Transforaminal Epidural Injection Using Kambin’s Triangle Approach

Lee J, Jo D, Song S et al. · 2020 · Journal of Pain Research

Jongseok Lee,1 Daehyun Jo,2 Shinmi Song,1 Dahee Park,1 Dohyeong Kim,1 Jinyoung Oh1 1Department of Anesthesiology and Pain Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Pain Center, Pohang Wooridul Hospital, Pohang-si, Gyeongsangbuk-do, Republic of KoreaCorrespondence: Jinyoung OhDepartment of Anesthesiology and Pain Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-Ro, Gangnan-Gu, Seoul, Republic of KoreaTel +82-2-2019-3600Fax +82-2-2019-4833Email sgcms3@gmail.comPurpose: Dispersion of contrast media

Negative / Null Result ReportOpen accessMedicine

Depression in Parkinson's disease: A case-control study.

Yu-Hsuan Wu, Yi-Huei Chen, Ming-Hong Chang et al. · 2018 · PLoS ONE

To evaluate the association between Parkinson's disease (PD) prognosis and the patient's onset of depression.A total of 353 patients with newly-diagnosed PD and a history of depression were enrolled. On the basis of the onset of depression before or after PD diagnosis, we divided participants into PD patients with pre- or post-diagnostic depression. Cox's regression analysis was used to detect risks between the onset of depression and outcomes (including death, accidental injury, dementia, and aspiration pneumonia). The association between the onset of depression and levodopa equivalent dosage

View details →DOI: 10.1371/journal.pone.0192050
Negative / Null Result ReportOpen accessMedicine

Clinical characteristics of gout patients with shoulder joints involved from 24 cases

WANG Yibo, HAN Yingdong, XIE Tiange, WU Juan, DI Hong, ZHANG Yun, ZENG Xuejun · 2025 · Jichu yixue yu linchuang

Objective To characterize the clinical features of the group of gout patients to facilitate earlier identification, and optimize the diagnosis and treatment of the condition. Methods The retrospective study analyzed 24 gout patients with shoulder joint(s) involved and consulted by physicians of Peking Union Medical College Hospital from March 2021 to April 2025, while 70 outpatient gout patients matched by clinical course duration and sex were enrolled as control group. Clinical data including medical history, laboratory tests, therapeutic interventions. Prognosis was systematically collected

View details →DOI: 10.16352/j.issn.1001-6325.2025.11.1485
Negative / Null Result ReportOpen accessSurgery

A new proposal for laparoscopic left colectomy in a rat model

Leonardo de Castro Durães, Eliana Ferreira Ribeiro Durães, Pedro Felipe Silva de Freitas et al. · 2013 · Acta Cirúrgica Brasileira

PURPOSE: To evaluate the feasibility and safety of a new technique for laparoscopic segmental colectomy and primary anastomosis in the left colon of rats. METHODS: Thirty rats were randomly assigned to three groups of ten animals each. All animals underwent segmental resection of the left colon and end-to-end anastomosis. In Group I, the animals underwent laparoscopic surgery with carbon dioxide pneumoperitoneum at a pressure of 5 mmHg. In Group II, the animals underwent pneumoperitoneum with carbon dioxide at a pressure of 12 mmHg. In Group III, the control group, the animals underwent open s

Negative / Null Result ReportOpen accessInternal medicine

Correlation of Moxifloxacin Concentration, C-Reactive Protein, and Inflammatory Cytokines on QTc Interval in Rifampicin-Resistant Tuberculosis Patients Treated with Shorter Regimens

Tutik Kusmiati, Ni Made Mertaniasih, Johanes Nugroho Eko Putranto et al. · 2022 · Acta Medica Indonesiana

Background: Drug-resistant tuberculosis (DR-TB) is a global health concern. QTc prolongation is a serious adverse effect in DR-TB patients receiving a shorter regimen. This study aimed to evaluate the correlation of moxifloxacin concentration, CRP, and inflammatory cytokines with QTc interval in DR-TB patients treated with a shorter regimen. Methods: This study was performed in 2 groups of rifampicin-resistant (RR-TB) patients receiving shorter regimens. Correlation for all variables was analyzed. Results: CRP, IL-1β, and QTc baseline showed significant differences between 45 RR-TB patients on

Negative / Null Result ReportOpen accessMedicine (General)

Pulsed magnetic field versus ultrasound in the treatment of postnatal carpal tunnel syndrome: A randomized controlled trial in the women of an Egyptian population

Dalia M. Kamel, Nashwa S. Hamed, Neveen A. Abdel Raoof et al. · 2017 · Journal of Advanced Research

The aim of this study was to compare the effects of pulsed electromagnetic field versus pulsed ultrasound in treating patients with postnatal carpal tunnel syndrome. The study was a randomized, double-blinded trial. Forty postnatal female patients with idiopathic carpal tunnel syndrome were divided randomly into two equal groups. One group received pulsed electromagnetic field, with nerve and tendon gliding exercises for the wrist, three times per week for four weeks. The other group received pulsed ultrasound and the same wrist exercises. Pain level, sensory and motor distal latencies and con

View details →DOI: 10.1016/j.jare.2016.11.001
Failed Experiment ReportOpen accessDermatology

Efficacy and Safety of Zabedosertib, an Interleukin-1 Receptor-Associated Kinase 4 Inhibitor, in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase II Randomized Study

Stefan J. Jodl, Margitta Worm, Frauke Friedrichs et al. · 2025 · Dermatology and Therapy

Abstract Introduction Interleukin-1 receptor-associated kinase 4 (IRAK4) is expressed in various immune cells and regulates proinflammatory cytokine production. Its inhibition represents a novel, promising therapeutic option in the treatment of atopic dermatitis (AD). Zabedosertib (BAY1834845) is a potent, selective IRAK4 inhibitor that suppresses markers of local and systemic immune responses. This study aimed to evaluate the efficacy and safety of zabedosertib in adults with moderate-to-severe AD. Methods DAMASK was a randomized, double-blind, 12-week, placebo-controlled, phase 2a, proof-of-

View details →DOI: 10.1007/s13555-025-01505-z
Failed Experiment ReportOpen accessTherapeutics. Pharmacology

Effect of Linagliptin and Voglibose on metabolic profile in patients with Type 2 Diabetes: a randomized, double-blind, placebo-controlled trial

Girish Parthan, Shobhit Bhansali, Anura V. Kurpad et al. · 2018 · BMC Pharmacology and Toxicology

Abstract Background Dipeptidyl peptidase 4 (DPP4) inhibitors improve glycemic control by promoting GLP1-mediated glucose-dependent insulin secretion and suppression of glucagon. Sitagliptin and vildagliptin have been shown to improve insulin sensitivity in patients with type 2 diabetes mellitus (T2DM). However, these patients had uncontrolled blood glucose at inclusion; therefore, the improvement in insulin sensitivity observed in these studies could be attributed to the drug per se and/or reduction in glucotoxicity. This study examines the effect of linagliptin on insulin sensitivity and β-ce

View details →DOI: 10.1186/s40360-018-0228-z
Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry

Neurofeedback in patients with frontal brain lesions: A randomized, controlled double-blind trial

Christine Annaheim, Kerstin Hug, Caroline Stumm et al. · 2022 · Frontiers in Human Neuroscience

BackgroundFrontal brain dysfunction is a major challenge in neurorehabilitation. Neurofeedback (NF), as an EEG-based brain training method, is currently applied in a wide spectrum of mental health conditions, including traumatic brain injury.ObjectiveThis study aimed to explore the capacity of Infra-Low Frequency Neurofeedback (ILF-NF) to promote the recovery of brain function in patients with frontal brain injury.Materials and methodsTwenty patients hospitalized at a neurorehabilitation clinic in Switzerland with recently acquired, frontal and optionally other brain lesions were randomized to

View details →DOI: 10.3389/fnhum.2022.979723
Negative / Null Result ReportOpen accessEngineering (General). Civil engineering (General)

Properties of red sandstone-limestone-cement ternary composites: Hydration mechanism, microstructure, and high-temperature damage

Weichuan Zhang, Mingxian Zhao, Zhongyan Yang et al. · 2024 · Developments in the Built Environment

A significant amount of waste is generated during the sandstone mining process. This study explores the use of red sandstone waste as a supplementary cementitious material to address environmental concerns in cement production. The experimental methods include isothermal calorimetry, compressive strength testing, thermogravimetric analysis, X-ray diffraction, infrared spectroscopy, scanning electron microscopy, high-temperature damage testing (200, 600, and 900 °C), and mesoscopic image analysis. The experimental findings reveal the following: (1) Red sandstone powder enhanced cement hydration

View details →DOI: 10.1016/j.dibe.2024.100346
Failed Experiment ReportOpen accessMedicine

EVALUATION OF FLEXURAL STRENGTH OF DIFFERENT RESTORATIVE MATERIALS

Almira Ada Diken Türksayar, Simge Baytur · 2023 · Sabiad

Objective: The aim of this in vitro study was to compare the biaxial flexural strengths of permanent restorative materials produced by additive manufacturing and milling after thermal aging. Material and methods: For this study, three study groups were formed by producing disc-shaped specimens with a 3D printer (Form3, Formlabs) using permanent crown material (Permanent Crown, Somerville, MA) and two different resin-containing materials (Brilliant Crios,Coltene/ Whaledent; Cerasmart, GC Europe) by the milling method (n=10). The entire production process was carried out in accordance with the m

View details →DOI: 10.26650/jarhs2023-1200694
Negative / Null Result Report

P3569The effect of percutaneous renal revascularization upon cardiac structure and function in patients with significant atherosclerotic renal artery stenosis

D O Geavlete, C Beladan, D Deleanu et al. · 2019 · European Heart Journal

Abstract Introduction Different consequences concerning the cardiac function and structure in patients with renal artery stenosis (RAS) and completely different patterns of activation of the renin-angiotensin-aldosteron system were…

View details →DOI: 10.1093/eurheartj/ehz745.0431
Negative / Null Result ReportOpen accessAnimal culture

Is the establishment rate and fecundity of Haemonchus contortus related to body or abomasal measurements in sheep?

A. Idris, E. Moors, C. Budnick et al. · 2011 · Animal

The relationship among parasitological parameters, abomasal size and body size measurements was investigated in lambs following an experimental infection with Haemonchus contortus. In total, 100 lambs from five different genotypes (German Merino (GM), Texel × GM, Suffolk × GM, German Blackhead Mutton × GM and Ile de France × GM) were experimentally infected with 5000 infective third stage larvae of H. contortus at the time of weaning at 12 weeks of age. Four and six weeks after infection, individual faecal samples were collected for estimation of faecal egg counts (FECs). Furthermore, wither h

View details →DOI: 10.1017/s1751731111000292
Negative / Null Result ReportOpen accessMedicine (General)

The Distribution of Apolipoprotein E Gene Polymorphism and Apolipoprotein E Levels among Coronary Artery Patients Compared to Controls

Omer Atis, Semsettin Sahin, Koksal Ceyhan et al. · 2019 · Eurasian Journal of Medicine

Abstract Objective: Coronary artery disease (CAD) is a multifactorial disease that is caused by various genetics and environmental factors. Genetically, predisposition is an important component for CAD. The candidate apolipoprotein E (apoE) gene is the most studied one. ApoE is composed of e2, e3, e4 alleles and E2/2, E2/3, E2/4, E3/3, E3/4, E4/4 genotypes. In this study, the relationship between CAD and apoE polymorphism and apoE level has been studied in Tokat region. Materials and Methods: The study population is composed of 100 CAD patients diagnosed by coronary angiography and 100 control

View details →DOI: 10.5152/eurasianjmed.2015.25
Negative / Null Result ReportOpen accessDentistry

Evaluation of Shear Bond Strength and Adhesive Remnant Index of New-Generation Adhesive-Coated Bracket Systems In Comparison With Traditional Systems

Gökay Üstdal, Ayça Üstdal Güney, Eyüp Burak Küçük · 2024 · Current Research in Dental Sciences

Objective: To evaluate the shear bond strength (SBS) and the adhesive remnant index (ARI) of different traditional orthodontic adhesive systems and newly developed pre-coated adhesive systems.Methods: A total of 50 human maxillary premolars were bonded with Clarity advanced ceramic brackets using APC™ Flash-Free, APC™ PLUS, Transbond™ XT Light Cure, Opal® Bond™MV and, Blugloo™ adhesives. All samples underwent thermo-cycling. The SBS was determined using a testometric machine. A stereomicroscope was used to evaluate the adhesive remnant on debonded enamel surface. Differences among the adhesive

View details →DOI: 10.17567/currresdentsci.1555935
Negative / Null Result ReportOpen accessSpecial aspects of education

Reading Online in Foreign Languages: A Study of Strategy Use

Richard Tsan-Jui Cheng · 2016 · International Review of Research in Open and Distributed Learning

Scores of studies have established that when learning online, students must be equipped with different sets of strategies and skills than in a physical classroom setting (Anderson, 2003; Broadbent & Poon, 2015; Coiro, 2007; Leu et al., 2007; Michinov, Brunot, Le Bohec, Juhel, & Delaval, 2011; Salmon, 2013). The present study, by virtue of exploring foreign language learners’ online reading experience, aimed to identify the reading strategies that learners would use when engaged in online reading activities in the target foreign languages. Thirty-two foreign language learners whose native langu

View details →DOI: 10.19173/irrodl.v17i6.2567
Negative / Null Result ReportOpen accessMedicine

Evaluation of the Association Among Cerebrospinal Fluid Protein, Inflammatory Markers, and Electromyography in Pediatric Guillain-Barre Syndrome

Dilek Agircan, Ozlem Ethemoglu, Mustafa Calik et al. · 2024 · Haseki Tıp Bülteni

Aim: Previous studies have shown that the cerebrospinal fluid (CSF) protein level correlates with the number of demyelination criteria in electromyography in adult patients with Guillain-Barré syndrome (GBS), which is a potentially life-threatening postinfectious disease. We aimed to assess the association between CSF protein level, inflammatory markers, and electrophysiological values in the diagnosis of pediatric patients to act quickly in treating GBS. Methods: In this cross-sectional study, thirty-nine children with GBS were retrospectively analyzed from the medical records of patients who

View details →DOI: 10.4274/haseki.galenos.2024.9521
Negative / Null Result ReportOpen accessMedicine

Sensitivity of influenza virus to ultraviolet irradiation

Hessling, Martin, Gierke, Anna-Maria, Sicks, Ben et al. · 2022 · GMS Hygiene and Infection Control

Background: The measures implemented against the coronavirus pandemic also led to a sharp decline in influenza infections in the 2020/2021 flu season. In the meantime, however, the number of influenza infections has risen again; it is known from history that influenza viruses can also trigger severe pandemics. Therefore, we investigated the efficacy of ultraviolet radiation in the spectral range of 200–40 for inactivating influenza viruses.Materials and methods: The scientific literature was searched for published ultraviolet (UV) irradiation experiments with influenza viruses and the results

View details →DOI: 10.3205/dgkh000423
Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens

Influence of Pre‐Vaccination HPV Status on Vaccine Effectiveness Among Chinese Women: A Multicenter Cross‐Sectional Study

Lucia Li, Haiyue Wu, Yibo Chen et al. · 2025 · Cancer Reports

ABSTRACT Background and Aims Human papillomavirus (HPV) vaccines have been available in China for only 8 years, and routine HPV testing is not recommended prior to vaccination. Therefore, evaluation of HPV vaccine effectiveness and the impact of pre‐vaccination HPV infection status on vaccine protective effect in Chinese women is warranted. Methods From June 2022 to June 2023, women aged 18 to 50 years without a history of cervical or uterine excision were recruited from three medical institutions. Baseline characteristics were compared between vaccinated and unvaccinated participants, with in

View details →DOI: 10.1002/cnr2.70294
Negative / Null Result ReportOpen accessEducation (General)

Immersive poetry learning: a field study with middle school students

Vincent Reynaert, Vincent Reynaert, Jalal Possik et al. · 2024 · Frontiers in Education

IntroductionThe field of poetry learning is currently facing significant challenges, primarily due to a lack of motivation and interest among students. This has resulted in educators encountering difficulties in identifying suitable educational alternatives. To address the latter issue, immersive learning has emerged as a potential solution, as it has been demonstrated to enhance motivation and learning outcomes in a multitude of fields.MethodsIn light of the aforementioned considerations, this field study seeks to examine the potential of virtual reality (VR) tools in enhancing the memorizati

View details →DOI: 10.3389/feduc.2024.1463635
Negative / Null Result ReportOpen accessDentistry

COMPARATIVE EVALUATION OF THE EFFECT OF TITANIUM PLATELET-RICH FIBRIN VERSUS HYALURONAN BIOACTIVE COATING ON OSSEOINTEGRATION OF DENTAL IMPLANTS IN ESTHETIC ZONE (RANDOMIZED CONTROLLED CLINICAL TRIAL)

AHMAD ZAAZA, Nevien Mohamed, Gaffar El Halawani · 2025 · Alexandria Dental Journal

Introduction: Osseo-integrated dental implants were traditionally load-free for up to six months while they healed. Patients usually feel dissatisfied with the long loading times. Several studies have been conducted to improve osseointegration, decrease loading time, and increase patient satisfaction.Objectives: This study aimed to evaluate and compare both clinically and radiographically the effect of hyaluronic acid (HA) versus Titanium-Platelet Rich Fibrin (T-PRF) in enhancing osseointegration around anterior maxillary dental implants. Materials and Methods: Twelve patients with extracted m

View details →DOI: 10.21608/adjalexu.2024.282413.1497
Negative / Null Result ReportOpen accessMedicine

Frequency and Clinical Significance of Incidental Prostatic FDG uptake in FDG PET imaging

Elif Özdemir, Şeyda Türkölmez · 2020 · Ankara Medical Journal

INTRODUCTION: This study aims to disclose the frequency and clinical significance of incidental prostatic uptake during FDG PET imaging. METHODS: FDG PET images of 1839 male patients undergoing imaging for non-prostate and non-urinary bladder malignancy indications were retrospectively reviewed for the presence of incidental prostatic FDG uptake. Prostatic volume, calcification and the presence and pattern of FDG uptake were evaluated. Further follow-up prostatic evaluation results were comparatively assessed. RESULTS: Incidental prostatic FDG uptake was detected in 41 out of 1839 patients(2.2

View details →DOI: 10.5505/amj.2020.93653
Negative / Null Result ReportOpen accessMaterials of engineering and construction. Mechanics of materials

Investigation on the Microstructure and Mechanical Properties of T23 Steel of Super-Critical Final Boiler Reheater after Long-Term Service

DUAN Peng, LIU Zong-de, TAO Xiang-qian, GU Shu-chao · 2021 · Cailiao Baohu

At present, the changes of microstructure and mechanical properties of T23 steel after served for more than 50 000 h have been less studied.In this work, with using the heat-delivery surface tubes of a 600 MW super-critical boiler as research object, the T23 steel final reheater tubes at various positions after about 80 000 h of service time were tested by microstructure analysis, tensile properties tests at room temperature and 525 ℃ temperature, and the deterioration degree and difference in mechanical properties between back and meet smoke side of tubes after long-term service were investig

View details →DOI: 10.16577/j.cnki.42-1215/tb.2021.01.008
Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology

Utility of dynamic contrast enhancement for clinically significant prostate cancer detection

Eric V. Li, Sai K. Kumar, Jonathan A. Aguiar et al. · 2024 · BJUI Compass

Abstract Objective This study aimed to evaluate the association of dynamic contrast enhancement (DCE) with clinically significant prostate cancer (csPCa, Gleason Grade Group ≥2) and compare biparametric magnetic resonance imaging (bpMRI) and multiparametric MRI (mpMRI) nomograms. Subjects/patients and methods We identified a retrospective cohort of biopsy naïve patients who underwent pre‐biopsy MRI separated by individual MRI series from 2018 to 2022. csPCa detection rates were calculated for patients with peripheral zone (PZ) lesions scored 3–5 on diffusion weighted imaging (DWI) with availab

View details →DOI: 10.1002/bco2.415
Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system

Does the contralateral healthy ankle of patient with ipsilateral mechanical lateral ankle laxity show greater lateral ankle laxity? Evaluation of the anterior talofibular ligament by stress ultrasonography

Takuji Yokoe, Takuya Tajima, Shuichi Kawagoe et al. · 2022 · BMC Musculoskeletal Disorders

Abstract Background A number of studies have evaluated risk factors for lateral ankle sprain (LAS) or chronic lateral ankle instability (CLAI). However, the definitive risk factors for LAS or CLAI remain controversial. The purpose of this study was to evaluate whether the contralateral healthy ankles of subjects with ipsilateral mechanical lateral ankle laxity (group I) show greater lateral ankle laxity in comparison to the healthy ankles of bilateral healthy controls (group B). Methods From March 2020, anterior talofibular ligament (ATFL) lengths of young adult volunteers were cross-sectional

View details →DOI: 10.1186/s12891-022-05838-0