e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21318 results · page 419 of 711

Negative / Null Result ReportOpen accessMedicine

Comparison of Retinal Nerve Fiber Layer Thickness Measurements in Healthy Subjects Using Fourier and Time Domain Optical Coherence Tomography

I. Pinilla, E. Garcia-Martin, M. Idoipe et al. · 2012 · Journal of Ophthalmology

Purpose. To compare the retinal nerve fiber layer (RNFL) measurements using two different ocular coherence tomography (OCT) devices: Cirrus Fourier domain OCT and Stratus time domain OCT. To analyze reproducibility of Fourier domain…

View details →DOI: 10.1155/2012/107053
Negative / Null Result ReportMedicine

Reverse Shoulder Arthroplasty for Patients with Cuff Tear Arthropathy: Do Clinical Outcomes Differ by Inlay versus Onlay Design?

Prashant Meshram, Piotr Łukasiewicz, Laurence Okeke et al. · 2024 · Journal of shoulder and elbow surgery

BACKGROUND The influence of position of the humeral tray (inlay or onlay) on clinical outcomes in reverse shoulder arthroplasty (RSA) is a topic of debate. The purpose of this study was to compare clinical and radiographic outcomes of…

View details →DOI: 10.1016/j.jse.2024.03.052
Negative / Null Result ReportOpen accessMedicine

Hepatitis C seropositivity in lichen planus: a case control study in a tertiary care hospital

G. Narendra, Mowazaffin Ahmed, Potlapati Amruthavalli et al. · 2020

Background: Lichen planus (LP), an immune-mediated disorder, has been reported as an extra-hepatic manifestation of Hepatitis C virus (HCV) infection, especially in HCV hyper endemic areas such as southern Europe and Japan. In India, the…

View details →DOI: 10.18203/issn.2455-4529.intjresdermatol20200597
Negative / Null Result ReportOpen accessMedicine

Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography

Se-joon Oh, I. Lee, Soo-Geun Wang et al. · 2019 · Clinical and Experimental Otorhinolaryngology

Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an…

View details →DOI: 10.21053/ceo.2019.00766
Negative / Null Result ReportOpen access

Contribution of the practice of resistance exercises and the type of delivery to the diastasis of the rectus abdominis muscles in primiparous women

F. Pacheco, Késsia Magalhães Espíndola, Jéssica Rosa Rezende et al. · 2023 · Fisioterapia e Pesquisa

ABSTRACT Maternal organism suffers physiological and biomechanical changes during pregnancy, including the separation of rectus abdominis muscles (RAM). This cross-sectional study aimed to compare the distance between the RAM among…

View details →DOI: 10.1590/1809-2950/e22006523en
Negative / Null Result ReportOpen accessMedicine

Retrospective Analysis of Chinese Patients with Hepatocellular Carcinoma (HCC) undergoing Transcatheter Arterial Chemoembolization (TACE) with or without Prophylactic Antibiotic Therapy.

Jiu Chen, Guolin Wu · 2018 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

OBJECTIVE To assess the necessity of prophylactic antibiotic therapy in HCC patients undergoing transcatheter arterial chemoembolization (TACE). STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY The First Affliated Hospital,…

View details →DOI: 10.29271/jcpsp.2018.12.914
Negative / Null Result ReportOpen accessBiology

Genetic variation of the mitochondrial D-loop region containing mitochondrial transcription factor A (TFAM) binding sites is not associated with marbling in Wagyu × Limousin F2 crosses

T. Kunej, J. Michal · 2005 · Acta Agriculturae Slovenica

Mitochondrial transcription factor A (TFAM) is a nucleus-encoded protein that is essential for initiation of transcription and replication of mitochondrial DNA (mtDNA). It has been shown that TFAM binds the entire length of the mtDNA, but…

View details →DOI: 10.14720/aas.2005.86.2.15164
Negative / Null Result ReportOpen accessMedicine

Creatine Enhances the Effects of Cluster-Set Resistance Training on Lower-Limb Body Composition and Strength in Resistance-Trained Men: A Pilot Study

D. Bonilla, R. Kreider, J. Petro et al. · 2021 · Nutrients

Creatine monohydrate (CrM) supplementation has been shown to improve body composition and muscle strength when combined with resistance training (RT); however, no study has evaluated the combination of this nutritional strategy with…

View details →DOI: 10.3390/nu13072303
Negative / Null Result ReportOpen accessMedicine

Effect of subconjunctival injection with conbercept as an adjuvant to filtration surgery for open angle glaucoma: a prospective randomized interventional 6-month follow-up study.

Jing Zhang, Vikash Vikash, Ping Wang et al. · 2019 · International Journal of Ophthalmology

AIM To compare the safety and efficacy of subconjunctival injection with conbercept and 5-fluorouracil (5-FU) for open angle glaucoma (OAG) patients after filtration surgery. METHODS As a prospective randomized interventional trial, 36…

View details →DOI: 10.18240/ijo.2019.02.08
Negative / Null Result ReportOpen access

Stress Response and Analgesia During and after Robotic-Assisted Pelvic Exenteration

A. D. Lifanova, A. A. Grazhdankin, I. Lutfarakhmanov · 2024 · Creative Surgery and Oncology

Introduction. Thoracic epidural analgesia or thoracic epidural anaesthesia (TEA) and opioid-based intravenous multimodal analgesia (MMA) provide adequate control of perioperative pain, however, comparative data are still to be gathered.…

View details →DOI: 10.24060/2076-3093-2024-14-2-105-115
Negative / Null Result ReportOpen accessMedicine

Is the Serum Vitamin D Level at the Time of Hospital-Acquired Acute Kidney Injury Diagnosis Associated with Prognosis?

Lingyun Lai, Jing Qian, Yanjiao Yang et al. · 2013 · PLoS ONE

Background Low circulating vitamin D levels have been suggested to potentially contribute to acute complications in critically ill patients. However, in patients with acute kidney injury (AKI), whether vitamin D deficiency occurs and is a…

View details →DOI: 10.1371/journal.pone.0064964
Negative / Null Result ReportOpen accessMedicine

Efficacy of a multiple-component and multifactorial personalized fall prevention program in community-dwelling older adults at moderate-to-high fall risk: The PRE.C.I.S.A. Randomized Controlled Trial

Fabio La Porta, S. Caselli, G. Lullini et al. · 2022 · medRxiv

Background: The fall risk in the elderly is a major public health issue due to the immediate injury-related consequences and the risk of associated long-term disability. However, the delivery of effective interventions for fall prevention…

View details →DOI: 10.1101/2022.03.26.22272987
Negative / Null Result ReportMedicine

Low-intensity versus high-intensity home-based treadmill training and walking attainment in young children with spastic diplegic cerebral palsy.

K. Mattern-Baxter, J. Looper, Chuan Zhou et al. · 2020 · Archives of Physical Medicine and Rehabilitation

OBJECTIVE To compare the effect of low-intensity (LI) versus high-intensity (HI) TT on walking attainment and overall walking activity in children with cerebral palsy (CP). DESIGN Prospective, multi-site, randomized controlled trial…

View details →DOI: 10.1016/j.apmr.2019.09.015
Negative / Null Result ReportOpen accessMedicine

Hypoparathyroidism: what is the best calcium carbonate supplementation intake form?

Loraine Gollino, M. Biagioni, Nathalia Regina Sabatini et al. · 2017 · Brazilian Journal of Otorhinolaryngology

Introduction In hypoparathyroidism, calcium supplementation using calcium carbonate is necessary for the hypocalcemia control. The best calcium carbonate intake form is unknown, be it associated with feeding, juice or in fasting. Objective…

View details →DOI: 10.1016/j.bjorl.2017.10.010
Negative / Null Result ReportMedicine

How does variation of the bag volume in inert gas rebreathing cardiac output measurements influence the reproducibility in patients with pulmonary diseases?

F. Trinkmann, F. Kraus, M. Borggrefe et al. · 2011 · European Respiratory Journal

Background: Cardiac output (CO) is an important hemodynamic parameter, however its determination is difficult in daily clinical routine. Non-invasive inert gas rebreathing (IGR) showed promising results in recent investigations with the…

View details →DOI: 10.1183/13993003/erj.38.suppl_55.p1526
Negative / Null Result ReportOpen accessMedicine

Assessment of proprioceptive exercises in the treatment of rotator cuff disorders in nursing professionals: a randomized controlled clinical trial.

L. V. Martins, M. Marziale · 2012 · Brazilian Journal of Physical Therapy

BACKGROUND Shoulder pain in nursing professionals may lead to limitations in occupational and daily activities and consequently interfere with quality of life. OBJECTIVE To compare the effects of two physical therapy programs which…

View details →DOI: 10.1590/s1413-35552012005000057
Negative / Null Result Report

Growth Evaluation of Selfcrossed Progenies BC1F2 Experiencing Submerged and Non-submerged at BC1F1 and its Parents

Azzah Maulidya, Rujito Agus Suwignyo · 2024 · Biovalentia: Biological Research Journal

A non-tidal swamp is an option to increase the rice harvested land and production, however, its utilization still depends on the natural condition so the plants are vulnerable to submergence and drought stress. Developing dual-tolerant…

View details →DOI: 10.24233/biov.10.1.2024.432
Negative / Null Result ReportMedicine

Aortic valve repair decreases risks of VRE in AI at 10 years: a propensity score-matched analysis.

Habib Jabagi, V. Chan, M. Ruel et al. · 2021 · Annals of Thoracic Surgery

BACKGROUND Aortic valve repair(AVr) has emerged as a feasible and effective alternative to replacement(AVR) in patients with aortic insufficiency(AI), however, little data exists comparing outcomes. Thus, the objective of this study was to…

View details →DOI: 10.1016/j.athoracsur.2021.06.020
Negative / Null Result ReportOpen accessMedicine

Lateral Pterygoid Muscle Biometric Modifications in Pterygoid Process Fractures Associated With Mandibular Fractures.

R. Nicot, Thomas Roland-Billecart, Alexandre Srouji et al. · 2020 · Journal of oral and maxillofacial surgery

PURPOSE Pterygoid process fractures (PPFs) are classically associated with Lefort fractures but can also be encountered in association with other facial fractures such as mandibular fractures. The aim of this study was to estimate the…

View details →DOI: 10.1016/j.joms.2020.07.219
Negative / Null Result ReportOpen accessMedicine

Multiple-dose versus single-dose gonadotropin-releasing hormone agonist after first in vitro fertilization failure associated with luteal phase deficiency: A randomized controlled trial

Danni Qu, Yuan Li · 2020 · Journal of International Medical Research

Objective To evaluate the efficacy and safety of multiple- versus single-dose gonadotropin-releasing hormone agonist (GnRH-a) addition to luteal phase support (LPS), in patients with a first in vitro fertilization (IVF) failure associated…

View details →DOI: 10.1177/0300060520926026
Negative / Null Result Report

Stress level of nursing students at the clinical practicum in the University of Aguascalientes (Mexico)

Griselda-Paulina De-Lira-Padilla, Karen-Alondra Vallín-López, Violeta Compeán-Padilla et al. · 2025 · Frontiers in Education

Coping with stress is a process that involves a particular relationship between the individual and his/her environment. Nursing students are exposed to stressful situations during their practical training, due to the responsibilities they…

View details →DOI: 10.3389/feduc.2025.1605172
Negative / Null Result ReportMedicine

Effect and hemodynamics of remimazolam besylate on sedation of mechanically ventilated patients: a propensity score-matched study

Wenjie Xie, Xiaoyu Fang, Zhao-hong Shi et al. · 2026 · BMC Anesthesiology

Remimazolam besylate is a novel ultra-short-acting benzodiazepine sedative. This study aimed to evaluate its hemodynamics profiles during sedation in mechanically ventilated patients in the intensive care unit (ICU), compared with…

View details →DOI: 10.1186/s12871-026-03870-4
Negative / Null Result ReportOpen access

Differences in expression of interleukin-6 and tumor necrosis factor-alpha fallopian tubes non-patent and fallopian tubes patent

U. R. Budihastuti, Abdurahman Laqif, Eriana Melinawati et al. · 2024 · Bangladesh Journal of Medical Science

Background: Fallopian tube infertility results from sexually transmitted infections and pelvic inflammatory diseases. The most common causes of infertility in women are infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae.…

View details →DOI: 10.3329/bjms.v23i1.70753
Negative / Null Result ReportOpen accessMedicine

Postprandial changes in cardiometabolic disease risk in young Chinese men following isocaloric high or low protein diets, stratified by either high or low meal frequency - a randomized controlled crossover trial

A. Mok, S. Haldar, J. C. Lee et al. · 2015 · Nutrix Journal

BackgroundCardio-Metabolic Disease (CMD) is the leading cause of death globally and particularly in Asia. Postprandial elevation of glycaemia, insulinaemia, triglyceridaemia are associated with an increased risk of CMD. While studies have…

View details →DOI: 10.1186/s12937-016-0141-5
Negative / Null Result ReportOpen accessMedicine

EFFICACY OF SILODOSIN VS TAMSULOSIN IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA: A DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL

S. T. C. Ariwicaksono, R. B. Prasetyo, Nindra Prasadja et al. · 2019 · International Journal of Applied Pharmaceutics

Objective: Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate associated with aging. BPH can cause lower urinary tract syndrome (LUTS). Medical therapy for patients with moderate and severe LUTS symptoms…

View details →DOI: 10.22159/ijap.2019.v11s6.33558
Negative / Null Result Report

СООТНОШЕНИЕ МЕЖДУ ГЕНДЕРНЫМИ ПСИХОЭМОЦИОНАЛЬНЫМИ ХАРАКТЕРИСТИКАМИ И ШКОЛЬНОЙ УСПЕВАЕМОСТЬЮ В РАННЕМ ПОДРОСТКОВОМ ВОЗРАСТЕ

А.И. Боравова · 2024 · Асимметрия

В работе проведен сравнительный анализ психоэмоциональных особенностей учащихся средней школы. Установлены достоверно значимые различия эмоциональных личностных характеристик между мальчиками и девочками подросткового возраста в…

View details →DOI: 10.25692/asy.2024.18.1.003
Negative / Null Result Report

Comparison of Sickle Cell Disease Patient Experiences in Developed and Developing Countries: Insights from UK and India Patient Cohorts

Ashley Lai, Kim Z Summers, Orlando Agrippa et al. · 2024 · Blood

Background Sickle cell disease (SCD) is the most common genetic blood disorder, affecting millions globally with 300,000 new cases annually. ~14,000 people live with SCD in the UK, while the number exceeds 20 million in India. Differences…

View details →DOI: 10.1182/blood-2024-210767