A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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Dang M, Bishop Z, Schick KD et al. · 2026 · Child abuse & neglect
Background In child maltreatment investigations, forensic interviewers must elicit accurate narratives while prioritizing children's wellbeing in a safe environment that minimizes distress. While note-taking may help reduce suggestive…
Sumardiono Siswo, Meganingtyas Wahyudita, Cahyono Heri · 2025 · E3S Web of Conferences
Artificial rice is one of the food diversification efforts that can be made from non-rice foodstuffs to reduce dependence on rice. In this study, artificial rice was made from a composite flour as raw material composed of modified cassava flour (mocaf) (Manihot esculenta), sago flour (Metroxylon sago Rottb), yellow pumpkin flour (Cucurbita moschata L.), and soybean flour (Glycine max) in different formula ratios. Artificial rice was produced using the extrusion method at temperatures of 70, 80, and 90°C. In this study, the artificial rice was analyzed for chemical and physical properties (wate
Kristiina Aalto, Hannu Kautiainen, Anders Fasth et al. · 2025 · RMD Open
Introduction The age at the onset of juvenile idiopathic arthritis (JIA) can influence the trajectory of the disease. We aimed to clarify how age at the visit 6 months after the onset as a continuous variable affects long-term remission of JIA.Methods This study investigated 358 patients from the Nordic JIA cohort study. Age at diagnosis was analysed continuously. Three age groups were studied: under 3 years, 3–5 years and over 6 years of age. JIA was categorised as oligoarthritis, seronegative polyarthritis and others (enthesitis-related, psoriatic and undifferentiated arthritis). Clinical da
Seyed Mohammad Mousavi, Alireza Milajerdi, Memhdi Sshayanfar et al. · 2019 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Limited data are available on the relationship between dietary factors and risk of glioma. The current study was conducted to investigate the association between dietary acid load (DAL) and risk of glioma in Iranian adults. Methods: This case-control study was carried out on 128 patients with glioma and 256 healthy subjects (Matched for age and sex) in Tehran, Iran. A validated detailed food frequency questionnaire (FFQ) was used to assess dietary intakes of the participants. DAL was estimated using the protein to potassium ratio (Pro/K) and Glioma was diagnosed base
Mariyah Mariyah, Rita Mariati, Eko Harri Yulianto Arifin · 2025 · Ziraa'ah: Majalah Ilmiah Pertanian
Analysis of Paddy Farming Performance in Tenggarong Seberang with Stochastic Frontier Analysis Approach. Providing food, especially rice, requires efforts to increase the productivity of rice farming. Good farm management can be measured through technical efficiency. Tenggarong Seberang district is one of the centers of rice production in Kutai Kartanegara Regency and is also a rice supply area to other regions in East Kalimantan. The research aims to identify production factors that affect production, to analyze the technical efficiency and inefficiency factors in rice farming. The research w
Shan-bo Ma, Lun Liu, Xiang Li et al. · 2023 · BMC Complementary Medicine and Therapies
Abstract Background The dried bark of Ailanthus altissima (Mill.) Swingle is widely used in traditional Chinese medicine for the treatment of ulcerative colitis. The objective of this study was to explore the therapeutic basis of the dried bark of Ailanthus altissima (Mill.) Swingle for the treatment of ulcerative colitis based on Virtual Screening–Molecular Docking–Activity Evaluation technology. Methods By searching the Traditional Chinese Medicine Systems Pharmacology TCMSP Database and Analysis Platform, 89 compounds were obtained from the chemical components of the dried bark of Ailanthus
Ting-Ting Xu, Rui Cao, Yan-Ling Dong et al. · 2022 · PLoS ONE
This study aimed to analyze the factors of rapid attenuation of graft endothelium in the early stage after penetrating keratoplasty (PKP), with a view to guiding patients with PKP to better long-term outcomes. This study included 226 patients who underwent PKP with follow-up time >1 year at the Qingdao Eye Hospital of Shandong First Medical University from January 2018 to June 2020. Medical records were retrospectively studied, and donor factors, patient factors, and surgical factors were comparatively analyzed to clarify those affecting the rapid decay of graft endothelium after PKP. The medi
Mohamed Bedair M. Ahmed, Gomaa N. Abdel-Rahman, Salah H. Salem et al. · 2020 · Toxicology Reports
The current study was conducted to determine sulfonamides (SAs) and tetracyclines (TCs) residuals in farmed Nile Tilapia fish (Orechromis niloticus) using the solid phase extraction (SPE) technique and high performance liquid chromatography with diode array detection (HPLC-DAD). As well, to assess the potential health risk due to the consumption of contaminated fish following its household thermal processing. Tilapia samples were collected from four governorates in Egypt; El-Fayoum, Giza, Cairo, and Alexandria. The results showed that 56.3 % (27 out of 48 samples) of fish samples were free of
N. Piaskowska, T. Daszkiewicz, D. Kubiak et al. · 2016 · Asian-Australasian Journal of Animal Sciences
This study evaluated the effect of vacuum and modified atmosphere (40% CO2+60% N2, MA) packaging on the chemical composition, physicochemical properties and sensory attributes of chill-stored meat from 10 fallow deer (Dama dama) bucks at 17 to 18 months of age. The animals were hunter-harvested in the forests of north-eastern Poland. During carcass dressing (48 to 54 h post mortem), both musculus longissimus muscles were cut out. Each muscle was divided into seven sections which were allocated to three groups: 0, A, and B. Samples 0 were immediately subjected to laboratory analyses. Samples A
Hesham Azouz · 2019 · Egyptian Poultry Science
The objective of this study was to investigate the effect of dietary supplementation with turmeric (TU), hot pepper (HP), or a combination of them as a powder on productive performance and functional properties of table eggs local strain (Sinai strain) hens at late production phase . A total number of 105 Sinai hens, 59-wks-old were weighed individually and randomly distributed equally into seven experimental treatments of three replicates each. The experimental design consists of the following groups; the first group was fed the basal diet without studied supplements and served as a control.
Fariba Hadidi, Ali Ganjloo, Mohammad Hadi Fakoor · 2023 · مجله پژوهشهای علوم و صنایع غذایی ایران
Introduction The demand for non-dairy and reduced-calorie products has increased substantially for several reasons. Almond (Prunus dulcis) milk is highly appreciated by lactose-intolerant, hypertensive people and celiac patients whom are not able to consume animal's milk. Thus, the development of various non-dairy products is essential. Desserts are the most common and popular product containing high amount of fat and sucrose. The consumption of sucrose is restricted for diabetic people due to its high glycemic index. Stevia as a low-calorie sweetener is one of the sucrose substitutes in food
ebrahim abbasi, saeed hoshmand · 2016 · راهبرد مدیریت مالی
The purpose of this study is to investigate the effect of capital gain plans on return cumulative and buy (sell) pressure on the days around assembly. In this study, capital gain means shareholders benefit from receivables financing (stock rights) and conversion of retained earnings into new shares (profit share) for fixed investment and development. According to the price pressure hypothesis, issuance of new shares leads to an increase in supply and accordingly, the stock returns and trading volume are affected. 100 companies which over the years from 2003 to 2014 have increased their capital
Zhenhan Deng, Xueqin Gao, Hajime Utsunomiya et al. · 2022 · Bone Reports
Background and aims: Previous work has shown that oral losartan can enhance microfracture-mediated cartilage repair in a rabbit osteochondral defect injury model. In this study, we aimed to determine whether oral losartan would have a detrimental effect on articular cartilage and bone homeostasis in the uninjured sides. Methods: New Zealand rabbits were divided into 4 groups including normal uninjured (Normal), contralateral uninjured side of osteochondral defect (Defect), osteochondral defect plus microfracture (Microfracture) and osteochondral defect plus microfracture and losartan oral admi
Tety Anggita Safitri · 2013 · Jurnal Dinamika Manajemen
Tujuan penelitian ini adalah untuk menguji pengaruh asimetri informasi terhadap underpricing. Penelitian ini menggunakan sampel 63 perusahaan yang melakukan penawaran umum perdana di Bursa Efek Indonesia dalam kurun waktu 2005-2010. Analisis data menggunakan regresi linier berganda, yaitu menguji proksi asimetri informasi yang terdiri atas ukuran perusahaan, umur perusahaan, proporsi saham yang ditawarkan kepada masyarakat, reputasi underwriter dan reputasi auditor terhadap underpricing. Hasil penelitian ini mengindikasikan bahwa reputasi underwriter dan reputasi auditor berpengaruh terhadap u
Zerrin Tuncer, Turhan Soylu · 2012 · Türk Oftalmoloji Dergisi
Pur po se: To evaluate the long-term results of rigid gas permeable (RGP) contact lenses in severe keratoconic eyes. Ma te ri al and Met hod: Severe keratoconic eyes with RGP contact lenses were evaluated retrospectively. Re sults: Long-term follow-up results of RGP contact lenses applied to 59 eyes of 42 patients (25 women, 17 men) with a diagnosis of severe keratoconus were analyzed. Follow-up period was 3 to 12 years (mean: 6.57±3.60). The mean age at first exam was 25.88±9.10 years, the mean corneal curve K1 was 6.49±0.40 mm and K2 was 5.91±0.40 mm. Mean visual acuities with spectacles and
Zahra Talei Gharegheshlaghi, farzad ghayour, Hamzeh Didar · 2019 · پژوهشهای حسابداری و حسابرسی عملیاتی و عملکرد
Decisions and thoughts of managers of organizations have a crucial role in advancing organizational goals. So identify their personal characteristics that influence their decisions and can be the reason for incompetence and managerial inadequacies in different levels of management and leadership of the organizations is important.Corporate owners use corporate governance mechanisms to reduce the opportunistic behavior of managers and protect the rights of stakeholders. In this regard, the present study aims to investigate the type and direction of the effect of management behavioral aspects on
Haixing Zhang, Wei Shi, Shahzad Ali et al. · 2022 · Agronomy
Legume/maize intercropping has been practiced in many countries as a sustainable cropping system, but the effects of intercropping legumes with maize together with N application rates on biomass yield, quality, water-use efficiency (WUE), and nitrogen use efficiency (NUE) are limited under arid conditions in Northwest China. Field experiments were carried out in arid areas of Northwest China from 2019 to 2020 with three planting patterns (LM: Dolichos lablab ( Lablab purpureus L.)/silage maize ( Zea mays L.) intercropping; FM: Fodder soybean ( Glycine max L.)/silage maize intercropping; M: sil
Jeanni Otyne D. S., Alfira Sofia · 2026 · Jurnal Akademi Akuntansi
Purpose: This study aims to examine effect of ownership structure and social media exposure on Corporate Social Responsibility disclosure. Methodology/approach: Using purposive sampling, nine personal care companies listed on the Indonesia Stock Exchange (IDX) were selected over a three-year period, yielding 27 firm-year observations. Secondary data were sourced from annual reports, company official websites, and Instagram accounts. Data analysis employed descriptive statistics, classical assumption tests (normality, multicollinearity, autocorrelation, and heteroscedasticity), and multiple lin
ZHAO Guangqiang, NAN Dongqi, YUAN Siqi · 2024 · 陆军军医大学学报
Objective To explore the action mechanism of tauroursodeoxycholic acid (TUDCA) promoting intracellular clearance of Burkholderia pseudomallei (B. pseudomallei) in RAW264.7 macrophages. Methods After TUDCA of different concentrations were used to treat RAW264.7 cells pre-infected with B. pseudomallei for 8 h or not, flow cytometry was applied to detect the apoptosis of the infected and control cells. In addition, another endoplasmic reticulum stress (ERS) inhibitor 4-PBA was used to detect the apoptosis and proliferation of host cells after B. pseudomallei infection with Annexin-V/PI double sta
Winda Noor Nawang Wulan, Suharyati , Rosali · 2019 · Ekonomi dan Bisnis
The development of information and communication technology in the era of globalization is growing rapidly. This has a significant impact on internet usage in Indonesia. So that makes Indonesia a very potential market for e-commerce, which has triggered the emergence of various online stores in Indonesia. Achieving success in ecommerce business in online stores in Indonesia requires a strategy. Shopee is an ecommerce company that runs the C2C mobile marketplace business, which allows users to buy or sell goods through applications available on the iOS and Android platforms. This research is a
Tomoharu Takeuchi, Risa Nakamura, Megumi Hamasaki et al. · 2023 · BMC Research Notes
Abstract Objective Galectins are sugar-binding proteins that participate in many biological processes, such as immunity, by regulating host immune cells and their direct interaction with pathogens. They are involved in mediating infection by Schistosoma mansoni, a parasitic trematode that causes schistosomiasis. However, their direct effects on schistosomes have not been investigated. Results We found that galectin-2 recognizes S. mansoni glycoconjugates and investigated whether galectin-1, 2, and 3 can directly affect S. mansoni in vitro. Adult S. mansoni were treated with recombinant galecti
Yulu Miao, Bin Wang, Jing Hu et al. · 2022 · Frontiers in Pharmacology
Lung infection is a common complication induced by stroke and seriously affects the prognosis and life quality of patients. However, effective therapeutic strategies are still lacking. In the present study, the herb formula GCis was confirmed to prevent pulmonary infection induced by intracerebral hemorrhage (ICH). The animal model of lung infection induced by ICH, GCis (Ginseng Radix et Rhizoma, Aconiti Lateralis Radix Praeparata, and Cistanches Herba) was orally administrated every day for 7 days. Lung microbial biomass and pathological results showed that the GCis formula pretreatment signi
Noor Fitriya Mirta Liana Tata, Syaiful Anwar, Florentina Kusmiyati · 2022 · Jurnal Ilmiah Pertanian
Red chili (Capsicum annum L.) is a vegetable that has high economic value. However, red chili production has decreased because of seed deterioration, such as expired seeds. Seed invigoration attempts to maintain seed germination ability when it has deteriorated. Extracts of onion and banana weevil can be used for invigoration. The research aimed to know the effect of various natural hormones, soaking time, and interaction of the two treatments of expired red chili seeds on germination, growth, and production. The research used a factorial, completely randomized design (CRD), which consisted of
Nahla Tharwat Moussa Ahmed, Hany Ezzat Obaya, Azza Abd Elaziz Abd Elhadi et al. · 2025 · Вестник восстановительной медицины
INTRODUCTION. The double chin is an excessive accumulation of fat in the pre- and post-platysma that can manifest in various forms and sizes. Thin individuals might manifest a double chin, similar to those who are afflicted by obesity. It may result in a reduction in the definition of the mandible and give the perception of obesity or aging. AIM. To evaluate any effect of High-Intensity Focused Ultrasound (HIFU) on sleep quality measures in obese women with a double chin. MATERIALS AND METHODS. Typically, 60 women aged 35–50 years were selected from AL Qasr-Alaini Hospital and were equally div
Anna Keodara, Lukas Jeker, Lars Straub et al. · 2024 · Scientific Reports
Abstract Bees are often exposed to pesticides affecting physiological functions and molecular mechanisms. Studies showed a potential link between altered expression of energy metabolism related transcripts and increased homing flight time of foragers exposed to pesticides. In this study, we investigated the effects of thiamethoxam and pyraclostrobin on longevity, flight behavior, and expression of transcripts involved in endocrine regulation (hbg-3, buffy, vitellogenin) and energy metabolism (cox5a, cox5b, cox17) using radio frequency identification (RFID) technology and quantitative polymeras
Jerzy A Zoladz, Joanna Majerczak, Bruno Grassi et al. · 2016 · PLoS ONE
In this study we have examined the effect of prolonged endurance training program on the pulmonary oxygen uptake (V'O2) kinetics during heavy-intensity cycling-exercise and its impact on maximal cycling and running performance. Twelve healthy, physically active men (mean±SD: age 22.33±1.44 years, V'O2peak 3198±458 mL ∙ min-1) performed an endurance training composed mainly of moderate-intensity cycling, lasting 20 weeks. Training resulted in a decrease (by ~5%, P = 0.027) in V'O2 during prior low-intensity exercise (20 W) and in shortening of τp of the V'O2 on-kinetics (30.1±5.9 s vs. 25.4±1.5
Maria A. Rezvova, Pavel A. Nikishau, Miraslau I. Makarevich et al. · 2022 · Nanomaterials
Nanocomposites based on poly(styrene- block -isobutylene- block -styrene) (SIBS) and single-walled carbon nanotubes (CNTs) were prepared and characterized in terms of tensile strength as well as bio- and hemocompatibility. It was shown that modification of CNTs using dodecylamine (DDA), featured by a long non-polar alkane chain, provided much better dispersion of nanotubes in SIBS as compared to unmodified CNTs. As a result of such modification, the tensile strength of the nanocomposite based on SIBS with low molecular weight (M n = 40,000 g mol –1 ) containing 4% of functionalized CNTs was in
Irwan Mahakam Lesmono Aji, Raden Sutriono, Arna Diansyah · 2020 · Jurnal Belantara
This study aims to find out the effect of submersion by using 1% acetic acid, 100% palm juice, and 100% coconut water to break the dormancy of palm seeds at different maturity levels. The research was conducted in the Green House of Forestry Study Program, University of Mataram, using the experimental method with Complet Random Design (CRD) three factors. The first factor is the maturity level consists of 3 levels, the second factor is the submersion liquid substance consist of 3 levels, and the third factor is the period of submersion consist of 4 levels.The results of this study indicate tha
P. Formánek, V. Vránová · 2003 · Journal of Forest Science
The effect of thinning of young spruce stands by 500 trees/ha on biological activity in the soil profile was studied in the mountainous area of the Moravian-Silesian Beskids. The biological activity of soil was determined under optimal laboratory conditions by tests of soil respiration, catalase activity and intensity of cellulose decomposition. No statistically significant differences were found between the individual biological tests when the two experimental stands were compared (P-level 0.05). All biological activities within each stand were correlated, and significant correlations were fo
Mohamed Rashed, Asmaa Khodari · 2022 · Aswan University Journal of Environmental Studies
TiO2 was synthesized from titanium tetraisopropoxide in the presence of H2O and H2O2 to form TiO2(H2O) and TiO2(H2O2) respectively. Thermo gravimetric analysis (TGA) was utilized to investigate the thermal stability and select proper calcination temperatures of the solid powders used to prepare the oxides. Accordingly, TiO2 was obtained by calcination at 550 and 750°C. These oxides were characterized by TEM, XRD, FTIR, XRF and UV-Vis spectroscopy. Results showed that TiO2(H2O2) is more thermally stable than TiO2(H2O) and its nanoparticles are smaller. TiO2(H2O2)(550) was doped with palladium t