Failed Experiment ReportOpen accessMedicine
Çimen Ş, Altındağ N, Erginöz E et al. · 2026 · International journal of molecular sciences
The relationship between biochemical severity parameters and adenoma burden in primary hyperparathyroidism (PHPT) has been widely studied, although some variability across studies persists. This relationship is clinically relevant for…
View details →DOI: 10.3390/ijms27115034 Negative / Null Result ReportMedicine
Steiger, Almeida, Massini et al. · 2026 · Journal of functional morphology and kinesiology
Objectives: This study aimed to compare the acute effects of high-intensity resistance training (HIRT), low-intensity resistance training (LIRT), and low-intensity resistance training with blood flow restriction (LIRT-BFR) on heart rate…
View details →DOI: 10.3390/jfmk11020235 Negative / Null Result ReportMedicine
Trovato, La Marca, Simonini et al. · 2026 · Journal of personalized medicine
Background/Objectives: The Systemic Immune-Inflammation Index (SII), derived from routine blood counts, has emerged as a potential marker of systemic inflammation in psoriasis. However, its longitudinal behavior across different systemic…
View details →DOI: 10.3390/jpm16060323 Negative / Null Result ReportMedicine
Biancari, Dell'Aquila, Mäkikallio et al. · 2026 · Journal of cardiovascular development and disease
Background: The nature and prognosis of type A intramural hematoma (TAIMH) are not well established. In this study, we evaluated the early and late outcome after surgery for this emergency condition. Methods: The ERTAAD registry included…
View details →DOI: 10.3390/jcdd13060247 Negative / Null Result ReportMedicine
Han, Yoo, Kang et al. · 2026 · Diseases (Basel, Switzerland)
Psoriasis is a chronic systemic inflammatory disease associated with increased cancer risk; however, its relationship with colorectal cancer (CRC) remains unclear. This question is particularly relevant in Asia, where CRC incidence has…
View details →DOI: 10.3390/diseases14060200 Failed Experiment ReportMedicine
Knapper, Thomas, Hills et al. · 2026 · Blood
We assessed the addition of the tyrosine kinase inhibitor Quizartinib, following intensive chemotherapy and as maintenance, in patients aged >60 years with AML or high-risk MDS, regardless of FLT3 mutation status. 463 patients (median age…
View details →DOI: 10.1182/blood.2025032681 Negative / Null Result ReportMedicine
Rosso, Fico, Di Criscio et al. · 2026 · Frontiers in immunology
The diagnosis of Sjögren's Disease (SjD) remains challenging due to the non-specific nature of sicca symptoms and the need for invasive biopsies. This pilot study aimed to investigate the potential of salivary Substance P (SP), a…
View details →DOI: 10.3389/fimmu.2026.1851367 Negative / Null Result ReportMedicine
Yokogawa, Yoon, Lee et al. · 2026 · Cureus
Background and objective It remains unclear whether atlas hypoplasia is causative of symptomatic cervical canal stenosis or represents an independent and unrelated finding. There have been few dedicated studies describing atlas hypoplasia,…
View details →DOI: 10.7759/cureus.109541 Negative / Null Result ReportMedicine
Mahajan, Akhtar, Sharma et al. · 2026 · Asian journal of transfusion science
Due to rapid technological advancements, several new methods such as telephone (TP), e-mail, social media, WhatsApp (WA), and Short Message Services are being used as effectively among blood centers worldwide for postdonation communication…
View details →DOI: 10.4103/ajts.ajts_190_23 Negative / Null Result ReportMedicine
Chen, Spadaccini, Sahai et al. · 2026 · Endoscopy international open
Endoscopic ultrasound-guided choledochoduodenostomy using a lumen-apposing metal stent (EUS-CDSL) has been shown in randomized controlled trials (RCTs) to be effective compared with endoscopic retrograde cholangiopancreatography (ERCP) in…
View details →DOI: 10.1055/a-2863-1621 Failed Experiment ReportMedicine
Ren, Nan, Li et al. · 2026 · Annals of medicine
To evaluate the analgesic efficacy of thoracic paravertebral block (TPVB) with different doses of liposomal bupivacaine (LB) or ropivacaine in patients undergoing single-port thoracoscopic lung surgery. A total of 105 patients scheduled…
View details →DOI: 10.1080/07853890.2026.2687941 Failed Experiment ReportMedicine
Gauci, Millet, Jacquot et al. · 2026 · Journal of shoulder and elbow surgery
The efficacy of patient-specific guides (PSGs) in improving accuracy and reducing the number of outliers in glenoid implant positioning in anatomic total shoulder arthroplasty has been clearly shown. However, long-term clinical benefit in…
View details →DOI: 10.1016/j.jse.2026.06.018 Negative / Null Result ReportMedicine
Kim, Seo, Nam et al. · 2026 · Cancer research and treatment
Preclinical studies suggest that sodium-glucose cotransporter-2 inhibitors (SGLT-2is) may have cancer-preventive effects; however, clinical evidence remains inconclusive. Therefore, this study aimed to evaluate the association between the…
View details →DOI: 10.4143/crt.2025.1243 Negative / Null Result ReportMedicine
Huang, Xu, Qin et al. · 2026 · Lancet (London, England)
Successful reperfusion after endovascular thrombectomy does not consistently result in functional independence in acute ischaemic stroke. We aimed to assess the efficacy and safety of tirofiban, a glycoprotein IIb/IIIa receptor antagonist,…
View details →DOI: 10.1016/s0140-6736(26)00983-9 Negative / Null Result ReportMedicine
Harris, Housman · 2026 · Applied neuropsychology. Adult
Neuropsychological performance is influenced by demographic/premorbid factors in addition to acquired cognitive impairment. This study examined relationships between educational attainment, reading ability, and executive functions in a…
View details →DOI: 10.1080/23279095.2026.2693225 Negative / Null Result ReportMedicine
Pan, Luan, Zhang et al. · 2026 · PloS one
Scale-Invariant Feature Transform (SIFT) features are widely used in target recognition and tracking. This study aimed to exploit the robust performance of the SIFT algorithm to accurately calculate tumor tissue displacement during…
View details →DOI: 10.1371/journal.pone.0330578 Negative / Null Result ReportMedicine
Peretó Villaescusa, Coelho, Grillo et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Postoperative knee stiffness following total knee arthroplasty (TKA) is a challenging complication that may require surgical intervention when conservative treatment fails. Although manipulation under anesthesia (MUA) and arthroscopic…
View details →DOI: 10.1007/s00590-026-04838-3 Negative / Null Result ReportMedicine
Heigl, Paganetti, Honaker et al. · 2026 · Langenbeck's archives of surgery
The feasibility and impact of Enhanced Recovery after Surgery (ERAS) protocols in emergency settings remain poorly understood due to patient instability, limited preoperative optimization, and inconsistent protocol adherence. Therefore,…
View details →DOI: 10.1007/s00423-026-04114-2 Negative / Null Result ReportMedicine
Fajriani, Djawad, Tabri et al. · 2026 · Dermatology reports
Xerosis is a prevalent skin disorder among patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). While both Aloe vera cream 30% and urea cream 20% have been shown to improve skin hydration in cases of xerosis cutis,…
View details →DOI: 10.4081/dr.2026.10496 Negative / Null Result ReportMedicine
Fahmy, El-Geleel, Anwar et al. · 2026 · Journal of the American Dental Association (1939)
Caries is the most prevalent chronic disease in children, affecting more than 530 million people worldwide. Timely restoration of primary molars is critical for maintaining function and preventing premature tooth loss. The choice of…
View details →DOI: 10.1016/j.adaj.2026.03.026 Negative / Null Result ReportMedicine
Jesus, Alves, Resende · 2026 · CoDAS
To validate and standardize the online application of the Scale of Self-Perception of Central Auditory Processing Skills (EAPAC) - expanded for Brazilian adults. The EAPAC was expanded and answered by 1,274 Brazilian individuals aged 18 to…
View details →DOI: 10.1590/2317-1782/e20250215pt Negative / Null Result ReportMedicine
Inoue, Ono, Okazaki et al. · 2026 · Cureus
Objectives Early prediction of neurological outcomes in patients with out-of-hospital cardiac arrest (OHCA) is critical for guiding treatment decisions. Machine learning (ML) model and grey-white matter ratio (GWR), both derived from brain…
View details →DOI: 10.7759/cureus.109468 Negative / Null Result ReportMedicine
Kataruka, Sannyashi, Bhattacharjee et al. · 2026 · Cureus
Neuropathic ulcers occur mainly at the plantar aspect and correspond to areas with peak plantar pressure, usually seen in a sensory-deficient foot. Trophic ulcers are seen in diabetic neuropathy, post-leprosy, and any other neurological…
View details →DOI: 10.7759/cureus.109479 Negative / Null Result ReportMedicine
Harvey, Morita, Huynh et al. · 2026 · JMIR medical informatics
Health care providers spend an excessive amount of time within electronic medical record (EMR) systems documenting patient encounters, often amounting to hours of work outside of regular office hours. This affects physician productivity…
View details →DOI: 10.2196/84104 Negative / Null Result ReportMedicine
Bala, Akyazi, Eraslan et al. · 2026 · BMC veterinary research
Environmental noise is a non-specific stressor that can activate stress-response pathways and increase the production of reactive oxygen species, contributing to oxidative stress in the brain. Limbic regions such as the amygdala and…
View details →DOI: 10.1186/s12917-026-05658-7 Negative / Null Result ReportMedicine
Chen, Wen, Zheng · 2026 · Shock (Augusta, Ga.)
Sepsis is a clinical syndrome marked by a dysregulated host response to infection, impairing oxygen delivery and utilization and causing organ dysfunction. Hypoxemia, which can cause significant tissue and organ damage, commonly occurs in…
View details →DOI: 10.1097/shk.0000000000002865 Negative / Null Result ReportMedicine
Mod, Keskin, Can et al. · 2026 · International journal of impotence research
This study aimed to compare the effects of absorbable and non-absorbable sutures on postoperative erectile function, ejaculatory function and sexual satisfaction in patients undergoing penile fracture repair. In this single-center…
View details →DOI: 10.1038/s41443-026-01313-9 Negative / Null Result ReportMedicine
Fazal, Loya, Muayad et al. · 2026 · American journal of ophthalmology
Age-related macular degeneration (AMD) is a leading cause of central vision loss worldwide. Emerging evidence suggests that targeting dopaminergic pathways may influence AMD progression. This study evaluates whether levodopa ±…
View details →DOI: 10.1016/j.ajo.2026.06.037 Negative / Null Result ReportMedicine
Eroğlu, Taş, Ekici · 2026 · Zeitschrift fur Orthopadie und Unfallchirurgie
In hemiplegic patients, joint cartilage alterations may arise from impaired balance reactions, decreased selective motor control, abnormal muscle tone, or reduced weight shifting toward the affected limb. This study aimed to investigate…
View details →DOI: 10.1055/a-2887-2112 Negative / Null Result ReportMedicine
Seehra, Ellis, Doleman et al. · 2026 · Journal of surgical education
Compare the demographics of UK surgical trainees and Annual Review of Competence Progression (ARCP) panel members to assess proportional representation. Retrospective cross-sectional analysis of national trainee and assessor records, with…
View details →DOI: 10.1016/j.jsurg.2026.104018 