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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21314 results · page 400 of 711

Failed Experiment ReportMedicine

Optical myopia control interventions: Evaluation of methods and success in a real-world population.

Day M, Kearney S · 2026 · Optometry and vision science : official publication of the American Academy of Optometry

Purpose To explore methods of evaluating success of optical myopia control interventions, and to apply these methods retrospectively to a clinical population. Methods A retrospective cohort study was conducted on pediatric patients…

View details →DOI: 10.1002/ovs2.70075
Negative / Null Result ReportMedicine

Causal Impact of Primary Care and Publicly Funded Health Insurance on Catastrophic Health Spending From Climate-Sensitive Diseases in India.

Chaudhary D, Mukhopadhyay I · 2026 · Applied health economics and health policy

Background Universal health coverage has become central to health policy debates, particularly as a strategy to protect households from financial hardship and impoverishment related to out-of-pocket (OOP) spending. Many low- and…

View details →DOI: 10.1007/s40258-026-01051-5
Negative / Null Result ReportOpen accessMedicine

The mediating role of job and life satisfaction in the effect of psychological resilience on employee performance: evidence from the February 6 Kahramanmaraş (Türkiye) earthquakes.

Amırlı H, Gurbanli E · 2026 · BMC psychology

The purpose of this study is to investigate the mediating roles of job satisfaction (JS) and life satisfaction (LS) in the relationship between psychological resilience (PR) and employee performance (EP). Data for this study, which…

View details →DOI: 10.1186/s40359-026-04520-7
Negative / Null Result ReportMedicine

The combined and independent influence of food texture and a 'mindful eating' instruction on eating rate and food intake among Dutch primary schoolchildren.

Jager G, de Wild VWT, Camps G et al. · 2026 · Appetite

Eating rate (ER), the amount of food consumed per unit of time, is a key determinant of food intake, with faster ER associated with larger meal size. Research in adults has shown that both sensory properties like texture, and instructions…

View details →DOI: 10.1016/j.appet.2026.108697
Negative / Null Result ReportMedicine

Psychometric Analysis of the <i>Perceptions of Sex Offenders</i> Scale: Confirmatory Factor Analysis and Validity Correlates.

Rye BJ, Tuer AG, Hertz S · 2026 · Journal of child sexual abuse

This study is a psychometric analysis of the Perceptions of Sex Offenders (PSO) scale, a reconceptualization of the Community Attitudes Toward Sex Offender scale. Using a student sample, a confirmatory factor analysis was conducted. The…

View details →DOI: 10.1080/10538712.2026.2683983
Negative / Null Result ReportMedicine

Severe cryoglobulinaemic vasculitis associated with monoclonal gammopathy: a diagnostic challenge of masked deposits.

Fernandes BP, Esteves A, Pimenta AC et al. · 2026 · BMJ case reports

Monoclonal gammopathy of renal significance is characterised by kidney injury caused by nephrotoxic monoclonal immunoglobulins produced by a pathogenic B cell or plasma cell clone. Cryoglobulinaemia in this context may lead to severe…

View details →DOI: 10.1136/bcr-2025-269981
Negative / Null Result Report

Preoperative Monocyte-to-Lymphocyte Ratio Does Not Discriminate Prolonged Intensive Care Unit Stay After Coronary Artery Bypass Surgery: A Single-Center Retrospective Cohort Study

Peker¹ I, Özdemir¹ O, Kandemir¹ C et al. · 2026 · Preprint

Abstract Aim Prolonged intensive care unit (ICU) stay after coronary artery bypass graft (CABG) surgery is a significant clinical problem associated with increased morbidity, mortality, and healthcare costs. The aim of this study was to…

View details →DOI: 10.21203/rs.3.rs-9726889/v1
Negative / Null Result ReportOpen accessMedicine

Intravascular Imaging for Facilitated Coronary Interventions in DES Era.

Zeren G, Bakır EO, Tufaro V et al. · 2026 · Journal of cardiovascular development and disease

Intravascular imaging (IVI) was introduced 35 years ago to assess coronary artery pathology and plaque vulnerability. However, from its first applications it became apparent that it can also be useful in percutaneous coronary intervention…

View details →DOI: 10.3390/jcdd13010038
Negative / Null Result ReportMedicine

Artificial Liver Support.

Kim HK, Huang DT, Al-Khafaji A · 2026 · Journal of intensive care medicine

Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) both have high mortality rates without liver transplantation. Artificial liver support systems may benefit patients with liver failure, serving as a bridge to…

View details →DOI: 10.1177/08850666261445379
Negative / Null Result ReportMedicine

Employing Comics Storytelling to Promote Climate Change Mitigation: An Experimental Study Grounded on the Situational Theory of Public.

Guo Y, Wei D, Xu S et al. · 2026 · Risk analysis : an official publication of the Society for Risk Analysis

This study examines the potential of comics as an infotainment strategy for engaging the public in climate change mitigation from the perspective of the situational theory of public. A 2 × 2 × 2 factorial experiment (N = 320) was conducted…

View details →DOI: 10.1111/risa.70234
Negative / Null Result ReportMedicine

Transfusion of blood products to neonatal and pediatric extracorporeal membrane oxygenation patients: A prospective, observational study.

Barton R, Van Den Helm S, Yaw HP et al. · 2026 · Transfusion

Study question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis or mortality.…

View details →DOI: 10.1111/trf.70154
Failed Experiment ReportMedicine

Nivolumab and ipilimumab combination therapy for melanoma efficacy, safety and clinical integration in metastatic and adjuvant settings.

Afuh R, Ashinze P, Banerjee S et al. · 2026 · Discover oncology

Melanoma remains one of the most aggressive cutaneous malignancies, accounting for a disproportionate share of skin cancer-related mortality despite relatively lower incidence. Over the past decade, immune checkpoint inhibitors (ICIs) have…

View details →DOI: 10.1007/s12672-026-05202-x
Failed Experiment ReportMedicine

Repurposing GLP-1 receptor agonists and SGLT-2 inhibitors in neurodegeneration and metabolically at-risk populations: Myth or reality? An overview of randomized clinical trials.

Mourtzos MA, Patoulias D, Keklikoglou NM et al. · 2026 · Diabetes research and clinical practice

Neurodegenerative diseases (NDs) are increasingly recognized as multifactorial disorders in which neurometabolic dysfunction intersects with classic pathological processes, including protein misfolding, neuroinflammation, synaptic failure…

View details →DOI: 10.1016/j.diabres.2026.113345
Negative / Null Result ReportMedicine

Mpox therapeutics in the post-STOMP/PALM era.

Promer K, Brenner SB, Ostrer L et al. · 2026 · Current opinion in HIV and AIDS

Purpose of review This article reviews the evidence behind mpox antiviral therapies which are clinically available and/or or under clinical investigation. For much of the mpox epidemic, tecovirimat has been used compassionately but there…

View details →DOI: 10.1097/coh.0000000000001015
Negative / Null Result ReportMedicine

A review on antibiotic and non-antibiotic decolonization strategies of multidrug-resistant bacteria in the gastrointestinal tract.

Weirauch T, Yahav D, Zahavi I et al. · 2026 · Infection

The escalating global threat of antimicrobial resistance represents a critical challenge for contemporary medicine. Intestinal colonization by multidrug-resistant organisms (MDROs) is increasingly identified as a primary driver of…

View details →DOI: 10.1007/s15010-025-02718-2
Negative / Null Result ReportMedicine

Neopterin Levels in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation: A Potential Biomarker for Acute Graft-Versus-Host Disease?

Kirkiz Kayalı S, Deveci TS, Gülbahar Ö et al. · 2026 · Transplantation proceedings

Introduction Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for hematologic disorders. Acute graft-versus-host disease (aGVHD) remains a major cause of nonrelapse mortality. Distinguishing aGVHD from…

View details →DOI: 10.1016/j.transproceed.2026.04.038
Negative / Null Result Report

Brain Tissue Oxygenation in Critically Ill Patients with Spontaneous Intracerebral Hemorrhage: A Prospective Observational Study

Ferreira AV, Dias M, Silva PA et al. · 2026 · Preprint

Abstract Background Brain tissue oxygen pressure (PbtO₂) monitoring is increasingly used in neurocritical care, but whether PbtO₂ provides complementary information beyond conventional parameters such as intracranial pressure (ICP) and…

View details →DOI: 10.21203/rs.3.rs-9684567/v1
Negative / Null Result Report

Evaluating spatial learning and memory ability of juvenile Sebastes schlegelii: A case study based on the cross-shaped convertible T-maze experiment

Zhao Y, Zhao Q, Yu X et al. · 2026 · Preprint

Abstract Learning behavior is an important acquired behavior in fish, and the capacity for learning and memory plays a crucial role in foraging or anti-predator behavior. In this study, we selected the juveniles of S. schlegelii as the…

View details →DOI: 10.21203/rs.3.rs-9638734/v1
Negative / Null Result ReportMedicine

Kinematic joint angles do not predict energy expenditure index in sub-acute and chronic stroke survivors: An exploratory study.

Patel J, Patil S · 2026 · Journal of bodywork and movement therapies

Background Stroke survivors exhibit gait inefficiencies with increased energy expenditure, potentially linked to kinematic deficits. This exploratory study examined whether peak sagittal joint angles predict Energy Expenditure Index (EEI)…

View details →DOI: 10.1016/j.jbmt.2026.05.002