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Negative / Null Result ReportMedicine

Substance P as a potential salivary biomarker to differentiate Sjögren's disease from non-Sjögren sicca syndrome: a pilot study.

Rosso; Fico; Di Criscio; Priori; Grilli; Valentini; Retta; Tirassa · 2026 · Frontiers in immunology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

The diagnosis of Sjögren's Disease (SjD) remains challenging due to the non-specific nature of sicca symptoms and the need for invasive biopsies. This pilot study aimed to investigate the potential of salivary Substance P (SP), a…

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Metadata source: PubMed · DOI 10.3389/fimmu.2026.1851367