Negative / Null Result ReportOpen accessTechnology
Yanchun Yin, Chuanru Yao, Yueyong Han et al. · 2024 · Energy Science & Engineering
ABSTRACT As an effective means of coal burst prevention, large‐diameter drilling pressure relief technology have been widely used in coal burst mines in China. Engineering practice shows that drilling pressure relief has obvious time‐effect. Through the establishment of drilling pressure relief numerical model, the evolution law of stress field and plastic zone in different periods after drilling was studied. The evolution of the pressure relief effect of large‐diameter borehole is closely related to the development degree of cracks around the borehole. The stress transfer process after drilli
View details →DOI: 10.1002/ese3.1961 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Ruixue Yang, Xuejiao Zeng, Xierenguli Alimu et al. · 2025 · Cancer Immunology, Immunotherapy
Abstract Objective This study investigated the impact of innate lymphoid cell type 2 (ILC2s) on the function of regulatory T cells (Treg) and CD8+ T cells in chronic lymphocytic leukemia (CLL) through IL-9. Methods Peripheral blood samples were collected from CLL patients (n = 52) and healthy controls (n = 30). ILC2 proportions and IL-9 levels were assessed using flow cytometry and ELISA. Immunofluorescence staining was performed to stain GATA3, CRTH2, and IL-9 in cervical lymph nodes from CLL patients (n = 10) and control subjects with reactive lymphadenitis (n = 10). Correlation analysis bet
View details →DOI: 10.1007/s00262-025-04082-4 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Armin D. Tavakkoli, BA, Megan A. Clark, BE, Alireza Kheirollah, PhD et al. · 2024 · Advances in Radiation Oncology
Purpose: Ultra High Dose-Rate (UHDR) radiation has been reported to spare normal tissue, compared with Conventional Dose-Rate (CDR) radiation. However, important work remains to be done to improve the reproducibility of the FLASH effect. A better understanding of the biologic factors that modulate the FLASH effect may shed light on the mechanism of FLASH sparing. Here, we evaluated whether sex and/or the use of 100% oxygen as a carrier gas during irradiation contribute to the variability of the FLASH effect. Methods and Materials: C57BL/6 mice (24 male, 24 female) were anesthetized using isofl
View details →DOI: 10.1016/j.adro.2024.101492 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Minghui Lu, Jiajun Wei, Qiang Cai · 2026 · Frontiers in Neurology
BackgroundThe optimal timing for tracheostomy in patients with intracerebral hemorrhage extending into the ventricles who require mechanical ventilation remains controversial, and there is a paucity of evidence to guide clinical practice. This study aimed to elucidate the impact of early vs. late tracheostomy on clinical outcomes and complications in this population, utilizing multivariable models to identify risk factors and define the potential beneficiary population.MethodsThis single-center retrospective cohort study consecutively enrolled 157 patients with severe spontaneous intracerebral
View details →DOI: 10.3389/fneur.2026.1724717 Negative / Null Result ReportOpen accessForestry
Jones Akuaku, Rita Sam · 2025 · International Journal of Forestry Research
The African baobab (Adansonia digitata L.) is a priority Pan-African tree species. Insect pests that are associated with and damage domesticated baobab are largely unknown in the production areas of baobab. To identify and document insect pests associated with domesticated African baobab for the first time, mature and young domesticated baobab plants were, respectively, surveyed on the research fields and nursery of the Ho Technical University in Ho, Ghana. The survey targeted all insects found on baobab with the goal of documenting pests that infest baobab plants. Collected insect samples wer
View details →DOI: 10.1155/ijfr/6638081 Negative / Null Result ReportOpen accessGynecology and obstetrics
Wenwen Zhang, Huimin Tang, Qiucheng Jia et al. · 2024 · Clinical and Experimental Obstetrics & Gynecology
Background: To evaluate the effect of carbohydrate antigen 125 (CA125) and CA19-9 in distinguishing stage Ⅲ and Ⅳ endometriosis from benign and malignant tumors, and to explore whether it is related to the clinical features of the disease. Methods: In a retrospective cohort study based on clinical data from hospitals, a total of 183 patients with pathologically confirmed diagnosis of ovarian endometriotic cysts (OEC) in Hainan Provincial People’s Hospital for surgical treatment from January 2019 to August 2022 were selected as the case group, and a total of 276 cases of benign diseases, includ
View details →DOI: 10.31083/j.ceog5102045 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Aleš Kopal, Eva Mejzlíková, Jana Lízrová Preiningerová et al. · 2015 · Parkinson's Disease
Parkinson’s disease (PD) is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH). The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+) have structural changes of retina detected by an optical coherence tomography (OCT) in comparison with PD patients without visual hallucinations (PDH−). We examined 52 PD patients (18 with VH, 34 without VH) and 15 age and sex matched healthy controls. Retinal nerve fiber layer (RNFL) thickness and macular thickness and volume were assessed by OCT. Functional impa
View details →DOI: 10.1155/2015/709191 Negative / Null Result ReportOpen accessDentistry
Naser Sargolzaie, Vahid Reza Askari, Maryam Najjar et al. · 2024 · Journal of Dental School
Objectives This study aimed to investigate the effect of propolis-based mouthwash on the gingival parameters of generalized chronic gingivitis cases in a randomized controlled clinical trial. Methods A total number of 69 patients with generalized chronic gingivitis were randomly assigned into three groups (N=23): propolis, chlorhexidine, or placebo mouthwash. The gingival and bleeding indices were evaluated before and after two weeks of mouthwash use. Data analyses were performed using Kruskal-Wallis test, one-way analysis of variance, and paired t-test at p<0 .05. Results The average gingival
View details →DOI: 10.22037/jds.v42i4.45242 Negative / Null Result ReportOpen accessGeriatrics
Inderpal Singh, Chris Edwards, Anser Anwar · 2018 · Geriatrics
Single-room ward design has previously been associated with increased risk of inpatient falls and adverse outcomes. However, following quality initiatives, the incidence of inpatient falls has shown a sustained reduction. Benefits have also been observed in the reduction of hip fractures. However, one-year mortality trends have not been reported. The aim of this observational study is to report the trends in one-year mortality rates before and after implementing quality-improvement initiatives to prevent inpatient falls over the last 5 years (2012–2016). This retrospective observational study
View details →DOI: 10.3390/geriatrics3010009 Negative / Null Result ReportOpen accessAgriculture (General)
Luciene Martins Moreira, Louise Larissa May-de Mio · 2009 · Ciência e Agrotecnologia
A podridão parda é a doença mais importante para a cultura do pessegueiro, entretanto, no Brasil são escassos os trabalhos realizados a campo visando o seu controle. Objetivou-se, neste trabalho, selecionar fungicidas em laboratório e avaliar a sua eficiência e de fosfitos a campo, para o controle da podridão parda monitorando as fases de desenvolvimento de frutos e pós-colheita, além de avaliar as características qualitativas dos frutos. O experimento de campo foi realizado com seis tratamentos e quatro repetições: três fungicidas pré-selecionados in vitro (iminoctadine tris albesilate, myclo
View details →DOI: 10.1590/s1413-70542009000200007 Negative / Null Result ReportOpen accessSurgery
Cheol Woo Park, Myung Ju Lee, Yun Ik Jung · 2018 · Archives of Aesthetic Plastic Surgery
Background Identifying problems and making a surgical plan through a preoperative analysis is important in facial aesthetic surgery. Thus, popular conceptions of an attractive face must be analyzed beforehand. The landmarks used as reference points may change after rhinoplasty, resulting in errors in the prediction and assessment of outcomes. To reduce such errors, it is advantageous to use reference points and landmarks that are subject to minimal variation. This study measured and analyzed landmarks with little preoperative and postoperative variation in rhinoplasty, and established appropri
View details →DOI: 10.14730/aaps.2018.24.3.105 Negative / Null Result ReportOpen accessVeterinary medicine
Stephanie Bond, Renaud Léguillette · 2024 · Journal of Veterinary Internal Medicine
Abstract Background Nebulized administration of dexamethasone on cytokine regulation in horses with moderate asthma has not been investigated. Objective To investigate the changes in expression of inflammatory cytokine mRNA after nebulized administration of dexamethasone treatment of horses with moderate asthma. Animals Horses with naturally occurring moderate asthma (n = 16) and healthy control horses (n = 4). All horses were kept in a dusty environment during the study. Methods Prospective, parallel, randomized, controlled, blinded clinical trial. Blood endogenous cortisol, tracheal mucus, a
View details →DOI: 10.1111/jvim.16983 Negative / Null Result ReportOpen accessLanguage and Literature
Ahmad M. Abd El-Aziz · 2022 · Wadī Al-Nīl Lil Dirāsāt wa Al-Buẖūṯ Al-Insāniyyaẗ wa Al-Iğtimāʿiyyaẗ wa Al-Tarbawiyyaẗ
This paper tries to investigate if there is a difference in the memory recall of emotional words between Arabic-English bilinguals. The methodology involves an experiment of free-recall responses to emotional word stimuli by 68 Egyptian Arabic-English bilinguals where the Arabic language is their native language (L1) and English language is their second language (L2). The participants divided into early English learners who acquired L2 at year 6, and late English learners who acquired L2 at year 12. A design of 2 x 2 x 3 three-way mixed ANOVA was administered with three independent variables;
View details →DOI: 10.21608/jwadi.2022.253441 Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Philip J Batterham, Alison L Calear, Matthew Sunderland et al. · 2021 · Journal of Medical Internet Research
BackgroundPsychosocial, self-guided, internet-based programs are effective in treating depression and anxiety. However, the community uptake of these programs is poor. Recent approaches to increasing engagement (defined as both uptake and adherence) in internet-based programs include brief engagement facilitation interventions (EFIs). However, these programs require evaluation to assess their efficacy. ObjectiveThe aims of this hybrid implementation effectiveness trial are to examine the effects of a brief internet-based EFI presented before an internet-based cognitive behavioral therapy self-
View details →DOI: 10.2196/23029 Negative / Null Result ReportOpen accessMedicine (General)
Angelo Mottaran, Amelio Ercolino, Lorenzo Bianchi et al. · 2023 · Medicina
Background and Objectives : The aim of this article is to present a single-surgeon, open retroperitoneal lymph node dissection (RPLND) series for testicular cancer in a high-volume center. Materials and Methods : We reviewed data from patients who underwent RPLND performed by an experienced surgeon at our institution between 2000 and 2019. We evaluated surgical and perioperative outcomes, complications, Recurrence-Free Survival (RFS), Overall Survival (OS), and Cancer-Specific Survival (CSS). Results : RPLND was performed in primary and secondary settings in 21 (32%) and 44 (68%) patients, res
View details →DOI: 10.3390/medicina59010133 Negative / Null Result ReportOpen accessSports medicine
Genevieve Fraipont, Victor Hung, Michelle McGarry et al. · 2025 · Orthopaedic Journal of Sports Medicine
Objectives: The medial ulnar collateral ligament (UCL), the radiocapitellar joint, and the posteromedial olecranon are the constraints of the elbow that are often injured during the late cocking and early acceleration phases of throwing. Osteochondritis dissecans (OCD) of the capitellum usually occur in adolescents participating in baseball due to repetitive compression force and excessive valgus torque within the radiocapitellar joint. Currently, there is conflicting literature on how location and size of osteochondral defects effect elbow valgus angulation. The purpose of this study was to q
View details →DOI: 10.1177/2325967125s00017 Negative / Null Result ReportOpen accessPhysics
Bahadir Tamer · 2021 · EPJ Web of Conferences
The MIT BEAVRS benchmark problem, which was primarily setup for the verification and validation of high-fidelity tools that have coupled neutron transport, thermal-hydraulics, and fuel isotopic depletion models, has also found extensive usage in the reactor physics community for validating core analysis tools. The primary purpose of this paper is to provide an accurate, comprehensive evaluation of the BEAVRS benchmark with CASMO5 and SIMULATE5 codes. The CMS5 calculated results for low-power physics tests (hot zero power critical boron, control rod worth and isothermal temperature coefficients
View details →DOI: 10.1051/epjconf/202124706022 Negative / Null Result ReportOpen accessInternal medicine
Cansu Önlen Güneri, Hamza Malik Okuyan, Gülay Gülbol Duran et al. · 2022 · Ķazaķstannyṇ Klinikalyķ Medicinasy
Aim: Patients infected with the hepatitis B virus (HBV) are at a higher risk of cirrhosis and hepatocellular carcinoma. Despite the recent advancement of antiviral therapy, many patients still cannot respond to existing therapies. Hence, to detect the changes in liver function earlier, non-invasive methods are needed. Long non-coding RNAs (lncRNAs) play important roles in essential biological process as well as human cancer. LncRNAs may be used as biomarkers in human diseases. Thus, in this study, we purposed to analyze the expression levels of lncRNAs (HOX transcript antisense RNA (HOTAIR), m
View details →DOI: 10.23950/jcmk/12662 Negative / Null Result ReportOpen accessMedicine
Shiro Okumura, Hironori Koga, Kuniyo Inouye et al. · 2014 · Toxins
Parasporin-4 (PS4) is an aerolysin-type β-pore-forming toxin produced by Bacillus thuringiensis strain A1470. It exhibits specific cytotoxicity against human cancer cell lines; therefore, it is expected to be useful for the diagnosis and treatment of particular types of cancer cells. We examined the acute toxicity of PS4 on ICR mice. The LD50 value was 160 μg/kg by a subcutaneous route. Potassium, ammonium, magnesium ion, creatinine, and urea nitrogen decreased in urine by the injection of PS4. Simultaneously, creatinine and urea nitrogen in mice serum increased. These results imply that PS4 i
View details →DOI: 10.3390/toxins6072115 Negative / Null Result ReportOpen accessMedicine
Yanwei Li, Dongchuan Yu · 2015 · PLoS ONE
Children's emotion word comprehension (EWC) has constantly received a great deal of attention in developmental science. However, since previous reports focused on only English emotion vocabulary, researchers thus far remained unclear as to the developmental trajectories of EWC (to Chinese emotion words) in Chinese children, let alone the cross-cultural difference of EWC in different languages (i.e., English V.S. Chinese). Furthermore, the influence of valence on EWC, as well as the interaction mechanism between EWC and empathy, has not been fully investigated. Finding answers to these research
View details →DOI: 10.1371/journal.pone.0143712 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Yong Li, Yong Li, Junlan Wu et al. · 2022 · Frontiers in Oncology
ObjectiveBrain metastasis from colorectal cancer (CRC) is rare. Although stereotactic radiotherapy (SRT) and stereotactic radiosurgery (SRS) are effective treatments for brain metastasis, reports on brain metastasis of CRC are limited. This study compared the efficacy of SRT and SRS for the treatment of brain metastases from CRC and analysed the related factors to reveal the specificity CRC-derived brain metastasis.MethodsA retrospective analysis of 116 patients with brain metastases from colorectal cancer was performed and included 56 patients in the SRT group and 60 patients in the SRS group
View details →DOI: 10.3389/fonc.2022.1060570 Negative / Null Result ReportOpen accessNuclear engineering. Atomic power
Jei Ha Lee, Cha Soon Kim, Soo Im Choi et al. · 2019 · Nuclear Engineering and Technology
Tritium is an important nuclide that must be monitored for radiation safety management. In this study, HTO was orally administered to rats at the level of 37 kBq (1 μCi) or 370 kBq (10 μCi) to examine tissue distribution and excretion levels. After sacrifice, wet and dry tissue samples were weighed and analyzed for tissue free-water tritium (TFWT) and organically bound tritium (OBT). The mean tissue concentrations of TFWT (OBT) were 30.9 (17.8) and 4.4 (8.1) Bq/g on days 7 and 13 at the 37 kBq level and 30.8 (64.6) Bq/g on day 17 at the 370 kBq level. To assess the cytogenetic damage due to tr
View details →DOI: 10.1016/j.net.2018.09.013 Negative / Null Result ReportOpen accessDentistry
S.Shojaeddin Shayegh, Parviz Amini, Kaveh Yaghmai et al. · 2016 · Journal of Islamic Dental Association of Iran
Background and Aim: Several methods are available for intraoral repair of chipped porcelain restorations by composite resin. Also, there is still controversy regarding the best method of porcelain repair in terms of bond strength and cost effectiveness. This study aimed to compare three methods of porcelain surface treatment on shear bond strength (SBS) of composite to porcelain. Materials and Methods: This in vitro, experimental study was conducted on 30 porcelain blocks with a metal base in three groups. In group 1, porcelain surface was etched with hydrofluoric (HF) acid and silanized. Afte
Negative / Null Result ReportOpen accessSurgery
Zhen Yu, Wenxing Xun, Pan Ren et al. · 2025 · World Journal of Surgical Oncology
Abstract Objective The purpose of our study was to evaluate the clinical effect of a facelift combined with a modified overlapping superficial musculoaponeurotic system (SMAS) flap for repairing facial depression caused by the resection of benign parotid lesions. Methods This retrospective, non-randomized observational study included 87 patients diagnosed with benign parotid tumors who underwent surgical treatment between June 2014 and September 2023. All patients were treated in our department or by the same surgical team after institutional transfer. All patients received surgery via a stand
View details →DOI: 10.1186/s12957-025-03862-7 Negative / Null Result ReportOpen accessMedicine (General)
M.C. Azevedo, E.D.R.P. Velloso, V. Buccheri et al. · 2014 · Brazilian Journal of Medical and Biological Research
In adults with non-promyelocytic acute myeloid leukemia (AML), high-dose cytarabine consolidation therapy has been shown to influence survival in selected patients, although the appropriate doses and schemes have not been defined. We evaluated survival after calculating the actual dose of cytarabine that patients received for consolidation therapy and divided them into 3 groups according to dose. We conducted a single-center, retrospective study involving 311 non-promyelocytic AML patients with a median age of 36 years (16-79 years) who received curative treatment between 1978 and 2007. The 13
View details →DOI: 10.1590/1414-431x20144059 Negative / Null Result ReportOpen accessMedicine
Yan Michael Li, Richard Francis Frisch, Zheng Huang et al. · 2021 · Asian Spine Journal
Study Design Retrospective chart review. Purpose This study compared the clinical and radiographic outcomes of patients treated with expandable and static interbody spacers following minimally invasive lateral lumbar interbody fusion (MIS-LLIF) with 12-month follow-up. Overview of Literature A common surgical option for the treatment of degenerative disk disease (DDD) is MIS-LLIF using static or expandable spacers to restore disk height (DH), neuroforaminal height (NH), and segmental lordosis. Static spacers may require excessive trialing and aggressive impaction, potentially leading to endpla
View details →DOI: 10.31616/asj.2019.0260 Negative / Null Result ReportOpen accessAgriculture (General)
WANG Xiaofan, WU Yong, ZHANG ZHONG Lili et al. · 2021 · Guan'gai paishui xuebao
【Background and Objective】 Magnetizing the water prior to irrigation is a new technology developed over the past decades in China. The objective of this paper is to investigate how different irrigation water sources alter the effects of the magnetization on photosynthesis, physiological and biochemical characteristics, as well as the yield of lettuce. 【Method】 The experiment was conducted in a solar greenhouse with the Italian lettuce taken as the model plant. It consisted of non-magnetization (M0) and magnetization (M1); added to these are three irrigation water sources: fresh water (T1), rec
View details →DOI: 10.13522/j.cnki.ggps.2020378 Negative / Null Result ReportOpen accessDentistry
Elanur Yıldızoğlu, Melih Manir, Muhammet Karadas · 2026 · BMC Oral Health
Abstract Background This in-vitro study aimed to assess the effects of whitening toothpastes on color and translucency changes and surface roughness of resin composites. Methods Disk-shaped resin composite samples from each composite (Clearfil Majesty Esthetic, Palfique Estelite Paste, and Charisma Smart) were made and randomly allocated into five groups (n = 10): Crest Pro Health Whitening, Advance White Pro, Sensodyne Extra Whitening, a control group (distilled water), and a positive control group (exposed to only stain). The samples were exposed to a tea solution and brushed for 30 days. Su
View details →DOI: 10.1186/s12903-026-08416-1 Negative / Null Result ReportOpen accessMedicine
Shermineh Heydari, Ladan Kashani, Mehrdad Noruzinia · 2021 · Iranian Journal of Allergy, Asthma and Immunology
Endometriosis is a common, chronic, inflammatory disorder in women, characterized by the presence of endometrial tissue outside the uterus cavity. The disease affects ~10% of women during their reproductive age. There is some debates on the pathogenesis of endometriosis and its mechanism among the scientists; therefore, different hypotheses have been suggested. According to Sampson theory, a possible mechanism for seeding ectopic endometriotic lesions is a dysregulation of endometrial mesenchymal stem cells (eMSCs). In the present study, we evaluated the expression of candidate genes in eMSCs
Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Akash Bihari Pati, Pritinanada Mishra, Santosh K Mahalik et al. · 2023 · Indian Journal of Urology
Introduction: Proximal hypospadias repair has many postoperative complications such as urethrocutaneous fistulae, wound dehiscence, and urethral stricture. The beneficial effect of estrogen to promote wound healing has been known. We designed a study to determine whether preoperative stimulation of tissue with estrogen can reduce the postoperative complications associated with wound healing in patients undergoing hypospadias repair. Methods: Patients with proximal hypospadias requiring two-stage repairs (chordee correction followed by urethral tubularization) were randomized to estrogen and co
View details →DOI: 10.4103/iju.iju_387_22 