Negative / Null Result ReportOpen accessMedicine
Trube J, Sabina M, Khanani A et al. · 2025 · American heart journal plus : cardiology research and practice
Introduction Inflammation is a key risk factor in cardiovascular diseases, such as atherosclerosis, and has been linked to increased mortality following myocardial infarction. While inflammation promotes tissue repair, sustained…
View details →DOI: 10.1016/j.ahjo.2025.100525 Negative / Null Result ReportOpen accessMedicine
Zacharia GS, Ashraf MH, Sosa F et al. · 2025 · World journal of gastrointestinal pharmacology and therapeutics
Metabolic dysfunction-associated steatotic liver disease (MASLD), recognized as the most prevalent liver disease worldwide and a leading cause of liver transplantation, is closely associated with type 2 diabetes, cardiovascular disease,…
View details →DOI: 10.4292/wjgpt.v16.i4.110827 Negative / Null Result ReportOpen accessMedicine
Höglinger G, Vandenberghe W, Woitalla D et al. · 2026 · BMJ neurology open
Background Preclinical evidence suggests targeting the mid-region of tau as a viable therapeutic strategy in diseases such as progressive supranuclear palsy (PSP): a rare, fatal, neurodegenerative tauopathy with no currently approved…
View details →DOI: 10.1136/bmjno-2025-001396 Negative / Null Result ReportMedicine
Sitbon O, Boucly A, Weatherald J et al. · 2025 · The European respiratory journal
Over the past three decades, several drugs have been developed to target three major dysfunctional pathways in pulmonary arterial hypertension (PAH), including the prostacyclin, endothelin and nitric oxide pathways. Despite these advances,…
View details →DOI: 10.1183/13993003.01830-2024 Negative / Null Result ReportMedicine
Riguzzi M, Verweij L, Naef R · 2025 · Intensive & critical care nursing
Objectives This study aims to demonstrate that family satisfaction with intensive care and decision-making is independent of sociodemographic family member and patient characteristics and the patient outcomes of mortality and length of…
View details →DOI: 10.1016/j.iccn.2025.104106 Negative / Null Result ReportMedicine
Shahin MM, Shashi KK, Shaikh R · 2025 · Cardiovascular and interventional radiology
Purpose This paper introduces a novel technique, cervical lymphangiogram, involving intranodal lymphangiogram through cervical lymph nodes. We will discuss our preliminary experience regarding the technique, safety, and applications,…
View details →DOI: 10.1007/s00270-025-04050-6 Negative / Null Result ReportMedicine
Oar EL, Rapee RM, Lavell CH et al. · 2025 · The British journal of clinical psychology
Objectives Exposure therapy is a well-established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are…
View details →DOI: 10.1111/bjc.12550 Negative / Null Result ReportMedicine
Giovannenze F, Del Vecchio P, Frondizi F et al. · 2025 · The Journal of hospital infection
Background Antimicrobial stewardship (AMS) programmes aim to enhance antibiotic prescription quality, reduce antibiotic use, and combat multi-drug-resistant pathogens. However, the optimal AMS intervention for different clinical settings…
View details →DOI: 10.1016/j.jhin.2025.05.017 Negative / Null Result ReportOpen accessMedicine
Walker-Pizarro N, Chan JL, Yu J et al. · 2026 · Tremor and other hyperkinetic movements (New York, N.Y.)
Clinical vignette A 59-year-old man with essential tremor (ET) and bilateral symptoms initially underwent left thalamic MRI-guided focused ultrasound (MRgFUS) at an outside institution to address tremor in the right upper extremity.…
View details →DOI: 10.5334/tohm.1194 Negative / Null Result ReportOpen accessMedicine
Harkins P, Cowley S, Conway R · 2025 · Journal of inflammation research
There is currently no gold standard diagnostic test or validated serological biomarker to monitor disease activity or inform disease prognostication in isolated Polymyalgia Rheumatica (PMR). This presents significant challenges as the…
View details →DOI: 10.2147/jir.s558175 Negative / Null Result ReportOpen accessMedicine
Steensbæk MT, Yousef S, Bahuet AR et al. · 2026 · Acta anaesthesiologica Scandinavica
Background Closed reduction of distal radius fractures is painful, and current analgesic strategies may be inadequate. Ultrasound-guided lateral infraclavicular brachial plexus block may offer complete analgesia and muscle relaxation,…
View details →DOI: 10.1111/aas.70246 Negative / Null Result ReportOpen accessMedicine
Santiago MDS, Wu GY · 2026 · Journal of clinical and translational hepatology
Alpha-1 antitrypsin deficiency (AATD) is an autosomal codominant genetic disorder caused by mutations in the SERPINA1 gene. It results in reduced circulating levels of alpha-1 antitrypsin (AAT), a serine proteinase inhibitor (PI) primarily…
View details →DOI: 10.14218/jcth.2026.00043 Negative / Null Result ReportOpen accessMedicine
Nawrocki PS, Rau BT · 2025 · Cureus
This report describes a case of hypokalemia-induced hemiplegia and altered mental status masquerading as an acute large vessel occlusion (LVO) stroke, and provides a brief discussion of stroke mimics. An air ambulance was dispatched to…
View details →DOI: 10.7759/cureus.94179 Negative / Null Result ReportMedicine
Wincewicz D · 2025 · Brain research
Pinpointing the bidirectional relationship between psychiatric and cardiovascular disorders holds the potential to tailor therapy and apply concepts of personalized treatment. Recent findings from both basic and clinical studies indicate…
View details →DOI: 10.1016/j.brainres.2025.149741 Negative / Null Result Report
Whitman T, Woolet J, Sikora MC et al. · 2025 · Preprint
Wildfires are natural disturbances characteristic of boreal forests. However, fire regimes around the world are changing, with effects on fire frequency and fire severity. Here, we present data from one and five years post-fire across 40…
View details →DOI: 10.1101/2025.03.29.646032 Negative / Null Result ReportOpen accessMedicine
Temürkol R, Güler H, Kaya A et al. · 2026 · Diagnostics (Basel, Switzerland)
Background: The estimation of the postmortem interval (PMI) remains a complex challenge in forensic medicine. While macroscopic, biochemical, and molecular methods are well-documented, postmortem functional approaches at the organ level…
View details →DOI: 10.3390/diagnostics16091266 Negative / Null Result Report
Flores-Andrade XA, Peralta-Prado AB, Porras-Rosales E et al. · 2025 · Preprint
Abstract Background: The mycobacterial and cytomegalovirus co-infection represents a critical intersection of infectious challenges, especially in the context of people living with human immunodeficiency virus infection. This relation…
View details →DOI: 10.21203/rs.3.rs-6405843/v1 Negative / Null Result ReportOpen accessMedicine
ELghareeb A, Dawaba M, Eldeeb M et al. · 2026 · International braz j urol : official journal of the Brazilian Society of Urology
Introduction Concomitant bladder neck incision (BNI) with posterior urethral valve ablation (VA) was proposed to mitigate the long-term sequela of posterior urethral valve (PUV) and reduce the reoperation rates. This study aimed to…
View details →DOI: 10.1590/s1677-5538.ibju.2025.0539 Negative / Null Result ReportMedicine
Schieda N, Morash C, Lavallee LT et al. · 2025 · BJU international
Objective To compare clinically significant prostate cancer (CS-PCa) detection by transperineal (TP) compared to transrectal (TR) magnetic resonance imaging (MRI)-ultrasonography (US) fusion prostate biopsy. Patients and methods Males with…
View details →DOI: 10.1111/bju.16831 Negative / Null Result ReportOpen accessMedicine
Diop S, Aparicio M, Mounier R et al. · 2026 · Journal of intensive care
Background Correction of "metabolic acidosis" by sodium bicarbonate is a common practice in intensive care unit or operating room. The physiological rationale underlying its use relies on the potential harmful hemodynamics effects of…
View details →DOI: 10.1186/s40560-026-00870-x Negative / Null Result ReportMedicine
Majumdar KS, Abhinav T, Panuganti A et al. · 2025 · JCO global oncology
Purpose The literature suggests that elective neck dissection (END) may be avoided in primaries with a depth of invasion (DOI) Materials and methods In this retrospective institutional chart review, pathologic N classification (pN) was…
View details →DOI: 10.1200/go-24-00451 Negative / Null Result ReportMedicine
Mercier C, Billiet C, Ost P et al. · 2025 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Purpose To test whether dose-escalated single fraction (SF) stereotactic body radiotherapy (SBRT) of 20 Gy to painful bone metastases is superior to conventional SF three-dimensional (3D) conformal radiotherapy (RT) to a standard dose of 8…
View details →DOI: 10.1200/jco-24-01447 Replication FailureMedicine
Schmidt C, Scheubeck G, Jurinovic V et al. · 2025 · Haematologica
Immunochemotherapy induces long-term responses in patients with follicular lymphoma. However, the toxicity of chemotherapy remains a relevant challenge. The Bruton tyrosine kinase inhibitor ibrutinib has shown significant activity in…
View details →DOI: 10.3324/haematol.2024.287162 Negative / Null Result ReportOpen accessMedicine
Paavonen J, Brunham RC · 2024 · Frontiers in cellular and infection microbiology
Localized provoked vulvodynia (LPV), also called vulvar vestibulitis or provoked vestibulodynia, is a major cause of dyspareunia that severely impacts sexual health. At the tissue level, lymphocytic inflammation and hyperinnervation are…
View details →DOI: 10.3389/fcimb.2024.1505845 Negative / Null Result ReportMedicine
Le Pallec C, Cerasuolo D, Cauvin JC et al. · 2025 · European journal of pediatrics
The respiratory rate-oxygenation index (ROXi) has been shown to be a reliable tool for predicting the risk of high-flow nasal cannula (HFNC) failure in adult patients with lower respiratory tract infections. However, the usefulness of the…
View details →DOI: 10.1007/s00431-025-06206-5 Negative / Null Result ReportOpen accessMedicine
Linz MS, Wang T, Friberg J et al. · 2026 · Trauma case reports
Introduction Traumatic hemipelvectomy is a rare operation, often performed for injuries caused by a high force mechanism such as a traffic or industrial accident, and often fatal. Most often performed emergently, here we report a traumatic…
View details →DOI: 10.1016/j.tcr.2026.101394 Negative / Null Result ReportMedicine
Wu TC, Lin CC · 2025 · Cancer prevention research (Philadelphia, Pa.)
The study by Downs and colleagues targets patients with non-muscle-invasive bladder cancer (NMIBC) to explore secondary/tertiary cancer prevention strategies. Utilizing a "window-of-opportunity" design, erlotinib was evaluated for its…
View details →DOI: 10.1158/1940-6207.capr-24-0491 Negative / Null Result ReportMedicine
Moon RE, Mitchell SJ · 2025 · Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
Gas can enter arteries (arterial gas embolism) due to alveolar-capillary disruption (caused by pulmonary overpressurization, e.g. breath-hold ascent by divers), veins (venous gas embolism, VGE) as a result of tissue bubble formation due to…
View details →DOI: 10.22462/10.12.2019.13 Negative / Null Result ReportOpen accessMedicine
Yalcin Y, Yalcin SE, Demir BC et al. · 2026 · BMC surgery
OBJECTIVE: The therapeutic role of lymphadenectomy in endometrial cancer remains controversial. Although systematic pelvic and para-aortic lymphadenectomy (PPLND) has been suggested to improve survival in certain patients, randomized…
View details →DOI: 10.1186/s12893-026-03640-6 Negative / Null Result ReportMedicine
Regidor E, Dionigi C, Ghoraishi M et al. · 2026 · Journal of periodontal research
Aims To evaluate the adjunctive effect of enamel matrix derivative (EMD) in the reconstructive surgical therapy of peri-implantitis. Methods Forty subjects (44 implants) affected by peri-implantitis (PPD ≥ 5 mm, positive BOP/SOP,…
View details →DOI: 10.1111/jre.13396 