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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21710 results · page 302 of 724

Negative / Null Result ReportMedicine

The Impact of the Number of Implantation-Window uNK Cells on Pregnancy Outcomes and Decidualization.

Huang B, Ma Y, Rao F et al. · 2026 · Reproductive sciences (Thousand Oaks, Calif.)

This study aims to further clarify the correlation between the quantity of natural killer (NK) cells in the endometrium and the successful implantation of embryos during the specific implantation window. Patients were stratified into four…

View details →DOI: 10.1007/s43032-026-02125-4
Negative / Null Result ReportMedicine

Comparative Analysis of Proton and Carbon-Ion Therapy for Head and Neck Cancer: LET-Dependent α/β Ratios in EQD2 and NTCP.

Wakisaka Y, Miyasaka Y, Tominaga Y et al. · 2026 · Radiation research

Proton therapy (PT) and carbon-ion therapy (CIT) differ not only in their physical dose characteristics but also in their biological effects, attributable to variations in fractionation protocols and linear energy transfer (LET). These…

View details →DOI: 10.1667/rade-25-00183.1
Negative / Null Result ReportMedicine

Threat or opportunity? Challenge vs hindrance appraisals of generative AI and self-regulated teaching among pre-service EFL teachers: A COR perspective.

Liu F, Wu H · 2026 · Acta psychologica

This study investigates how Chinese pre-service teachers of English as a foreign language (EFL) develop self-regulated teaching competencies in the face of disruptions posed by generative artificial intelligence (GenAI) and structural…

View details →DOI: 10.1016/j.actpsy.2026.106747
Negative / Null Result ReportMedicine

Structural reconfiguration of gluten-starch matrices driven by yeast fermentation and its effects on quality of fermented dried noodles.

Zhang G, Zhao P, Zhu L et al. · 2026 · Food chemistry

This study aimed to systemically investigate the effects of yeast fermentation (0-2% yeast, flour basis; 0.5-2 h) on gluten and starch structures, and cooking and textural properties of fermented dried noodles (FDN). Yeast fermentation…

View details →DOI: 10.1016/j.foodchem.2026.149417
Negative / Null Result ReportMedicine

Dysregulation of HIF-1α-regulated and thromboinflammatory genes may contribute to thrombotic risk in patients with BCR::ABL1-negative myeloproliferative neoplasms.

Morath O, Wolfrum T, Crodel C et al. · 2026 · Journal of thrombosis and haemostasis : JTH

Background Hypoxia-inducible factor-1α (HIF-1α) regulates multiple pathways involved in metabolism, inflammation, and coagulation and may contribute to thrombotic complications in patients with BCR::ABL1-negative myeloproliferative…

View details →DOI: 10.1016/j.jtha.2026.04.013
Negative / Null Result ReportMedicine

Persistent Chemotherapy-Induced Alopecia: Updates in Diagnosis and Treatment Persistent Chemotherapy Induced Alopecia: An Updated Approach.

Garza-Rodríguez V, Imbernon-Moya A, Hermosa-Gelbard A et al. · 2026 · Actas dermo-sifiliograficas

Chemotherapy-induced alopecia (CIA) is characterized by absent or incomplete hair regrowth after completion of chemotherapy. Alopecia that persists beyond 6 months after completing chemotherapy is defined as persistent chemotherapy-induced…

View details →DOI: 10.1016/j.ad.2026.104660
Negative / Null Result ReportMedicine

Autopolyploidy exacerbates dominance masking under negative frequency-dependent selection: evidence from sporophytic self-incompatibility in Arabidopsis arenosa and Arabidopsis lyrata.

Vekemans X, Kolesnikova U, Vlček J et al. · 2026 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Polyploidy is widespread within flowering plants, with 35% of extant species being recent polyploids. Whether and how polyploidy modulates the action of natural selection remains debated, and the particular case of balancing selection has…

View details →DOI: 10.1098/rstb.2025.0182
Negative / Null Result ReportMedicine

Asthma in Active Military Aircrew: Long-term Health and Flight Performance.

Angel O, Rittblat M, Freund O et al. · 2026 · The Israel Medical Association journal : IMAJ

Background Asthma poses unique challenges in aviation medicine. While strict criteria typically dictate waiver approvals in military aviators with asthma, the Israeli Air Force (IAF) applies a more individualized approach. Still, evidence…

Negative / Null Result ReportMedicine

Combined Hormonal Contraception with Low-Dose Ethinylestradiol is Associated with Modest Reduction of Breast Milk Volume when Administered Vaginally, but Not Orally.

Segev L, Weitzman G, Hijazi B et al. · 2026 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Background Combined hormonal contraception (CHC) is habitually not prescribed to breastfeeding women due to concerns of decreased milk production. This habit is based on inconclusive studies that examined lactation suppression of CHC with…

View details →DOI: 10.1177/15568253261450161
Negative / Null Result ReportMedicine

Back to work: exploring barriers and facilitators to return to work and work participation following traumatic amputation.

Hutchison A, D'Cruz K, Keeves J et al. · 2026 · Disability and rehabilitation

Purpose To explore barriers and facilitators to returning to work and work participation experienced by people following traumatic amputation. Methods An exploratory qualitative study was conducted with nineteen adults in Australia with…

View details →DOI: 10.1080/09638288.2026.2645396
Negative / Null Result ReportMedicine

Biomechanical assessment of intraocular lens stability and position based on suture and inlet variations in the Canabrava double-flanged technique.

Suh YK, Choi S, Yoon CK et al. · 2026 · Journal of cataract and refractive surgery

Purpose To evaluate how variations in suture type, suture length, and scleral outlet angle affect intraocular lens (IOL) positioning and fixation stability in the Canabrava technique, given ongoing concerns such as iris chafing and the…

View details →DOI: 10.1097/j.jcrs.0000000000001869
Negative / Null Result ReportMedicine

Differences in Cyclotorsion Compensation Between Low, Medium, and Large Angles in Myopic PRK: Visual and Refractive Results.

Ben Ephraim Noyman D, Safir M, Sommer A et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the differences in myopic photorefractive keratectomy (PRK) outcomes between small, medium, and large cyclorotational angle degrees. Methods This retrospective comparative study was conducted at Care Vision Laser…

View details →DOI: 10.3928/1081597x-20260218-02
Negative / Null Result ReportMedicine

Association between Plasma Uric Acid level and Mortality Rate in Children with Sepsis and Acute Kidney Injury.

Sadeghi Bojd S, Soleimani G, Yaghoubi S et al. · 2026 · Urology journal

Background Acute kidney injury is a common disease in hospitalized patients, which can have a significant impact on outcomes, including an increase in overall complications and mortality rates, criteria such as serum creatinine level,…

View details →DOI: 10.22037/uj.v23i00.8514
Negative / Null Result ReportMedicine

Accuracy of Continuous Glucose Monitoring in Adults With Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Surgery Under Stable and Dynamic Glucose Conditions.

Lizoain A, Vettoretti M, Ferreira A et al. · 2026 · Diabetes care

Objective Although continuous glucose monitors (CGMs) are increasingly used to detect and manage postbariatric hypoglycemia (PBH) and associated glucose variability, data on their accuracy in this population remain scarce. Research design…

View details →DOI: 10.2337/dc25-2724
Negative / Null Result ReportMedicine

Higher IVIG resistance in Kawasaki disease patients treated early after fever onset: a single-center retrospective study of 2,988 cases.

Wen J, Wu Y, Huang P et al. · 2026 · European journal of pediatrics

To investigate the impact of intravenous immunoglobulin (IVIG) timing on coronary artery outcomes and treatment response in children with Kawasaki disease (KD). This retrospective study analyzed 2,988 pediatric patients with Kawasaki…

View details →DOI: 10.1007/s00431-026-06931-5
Negative / Null Result ReportMedicine

Examining the relationship between organizational health, happiness and employee performance: The case of hospital employees.

Kalender S, Kişi M, Özkan O · 2026 · Work (Reading, Mass.)

BackgroundHealthcare workers face challenges such as intense work tempo, irregular working hours and high patient expectations. This situation may affect the happiness and performance of employees, as well as the quality of health…

View details →DOI: 10.1177/10519815261449929
Negative / Null Result ReportMedicine

Effects of Ayres sensory integration therapy versus conservative treatment in autism spectrum disorder.

Inam R, Shah S, Ullah MS et al. · 2026 · JPMA. The Journal of the Pakistan Medical Association

The study was conducted to evaluate the effects of Ayres sensory integration therapy versus conservative treatment in autism spectrum disorder. In a prospective randomised controlled trial, we assessed pre- and post-intervention scores of…

View details →DOI: 10.47391/jpma.21549
Negative / Null Result ReportOpen accessMedicine

Footwear effect on the orthopedic injury profile in ankle and foot trauma caused by motorcycle accidents.

de Lima HLN, Soares MJNL, Macedo SMMPC et al. · 2026 · Acta ortopedica brasileira

Motorcycle accidents represent a significant cause of trauma in developing countries such as Brazil. Within the possible lesions, lower limb injuries are among the most prevalent, with ankle and foot injuries causing a high incidence of…

View details →DOI: 10.1590/1413-785220263403e292429
Negative / Null Result ReportOpen accessMedicine

Evaluating the Serum Levels of CD73 in Patients with Head and Neck Squamous Cell Carcinoma.

Zare R, Ranjbar MA, Ebrahimi A et al. · 2026 · Journal of dentistry (Shiraz, Iran)

Background The expression of CD73 antigen is associated with different prognoses in different carcinomas. However, few studies have assessed the level of this marker in squamous cell carcinoma (SCC) as the most common malignancy of the…

View details →DOI: 10.30476/dentjods.2025.102855.2403
Negative / Null Result ReportMedicine

[Survey on the establishment of smoking areas in city halls in National Association of Directors of Health Departments of Designated Cities, West Block Conference].

Hamada M, Miyamura K, Kasamatsu M et al. · 2026 · [Nihon koshu eisei zasshi] Japanese journal of public health

Objectives In Tokyo, preventing passive smoking progressed during the 32nd Olympic Games. However, smoking areas remain in many local city halls, and tobacco product companies donate smoking areas in front of stations and near parks. A…

View details →DOI: 10.11236/jph.25-131
Negative / Null Result ReportOpen accessMedicine

Relationships Among Cognitive Distortions, Forgiveness of Others, and Self-Forgiveness in Psychiatric Outpatients with Depressive Disorders: A Cross-Sectional Study.

Saklamaz S, Akpınar H · 2026 · Healthcare (Basel, Switzerland)

Background : Depression is associated with cognitive, emotional, and interpersonal difficulties that may influence forgiveness-related processes. This study aimed to examine the relationships among cognitive distortions, forgiveness of…

View details →DOI: 10.3390/healthcare14111478