A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21290 results · page 303 of 710
Eldabe, Adel-Khattab, Beshay et al. · 2026 · BMC oral health
This clinical trial was conducted to compare the four types of static fully guided surgical guides (bilateral tooth-supported guides, unilateral tooth-supported guides, mucosa-supported complete arch guides, and stackable bony-supported…
Aprina, Rahayu, Prihartono et al. · 2026 · Korean journal of ophthalmology : KJO
To investigate the effect of higher cylindrical power and axis misalignment of toric SCL in mild and moderate astigmatism on visual acuity, contrast sensitivity, visual satisfaction, and vision acceptability. 20 astigmatic participants…
Yu, Yu, Sun et al. · 2026 · Frontiers in bioengineering and biotechnology
Proprioceptive deficits following anterior cruciate ligament (ACL) injury increase reliance on visual input in athletes after ACL reconstruction (ACLR). Visual disruption may therefore alter movement patterns and increase re-injury risk.…
El-Tallawy, Pergolizzi, Alsubaie et al. · 2026 · Cureus
Background  Postoperative pain management in children remains a significant challenge due to developmental differences in pain perception, reporting, and communication. However, limited evidence exists regarding age-specific…
Sykes, Brindle, Kazmi et al. · 2026 · ERJ open research
Azithromycin is beneficial in a multitude of respiratory diseases; however, its effects on both subjective and objective measures of cough have been less extensively studied. Traditional 24-h cough counting assessments are highly variable,…
Tsai, Huang, Wang et al. · 2026 · Integrative cancer therapies
BackgroundTraditional, complementary, and integrative medicine (TCIM) is an evolving field in oncology focused on managing cancer symptoms. Hydrogen water (HW) has gained attention for its antioxidant and anti-inflammatory properties, yet…
McComish, Brewster, Brizard et al. · 2026 · Transplant immunology
Human Leucocyte Antigen (HLA) sensitisation following red cell transfusion can disrupt planned transplantation and impair outcomes. We conducted a prospective, randomised controlled, double blinded, parallel arm study to evaluate the…
Ribeiro, Stuginski, do Amaral E Luna et al. · 2026 · Toxicon : official journal of the International Society on Toxinology
Snakebites represent a significant public health concern in tropical and subtropical countries. In 2025, approximately 21,000 incidents of snakebites were reported in Brazil, with 1.7% attributed to coral snakes. Although the incidence of…
Ferrari, Saracutu, Pontoriero et al. · 2026 · Journal of dentistry
To compare the outcome of short fiber reinforced composites, as a core material, with respect to conventional fiber post, for the reconstruction of anterior endodontically treated teeth (ETT), covered by a lithium disilicate crown.…
Chen, Han, Guo et al. · 2026 · International dental journal
To compare the accuracy, instrumentation time, and success rate of three dynamic navigation systems (DNSs)-infrared-active (IA), infrared-passive (IP), and visible light-passive (VP)-with freehand (FH) operation in locating root canals of…
Vastardis, Tolia, Pallazola et al. · 2026 · The Journal of surgical research
Preoperative handgrip strength (HGS) is a noninvasive estimate of muscle strength, and reduced HGS is associated with increased frailty and postoperative complications. However, best practices for preoperative HGS collection remain…
Ghimire, Sohrabi, Zhou et al. · 2026 · Microbial ecology
Over 90% of the mixotrophic algae surveyed require vitamin B 12 (B 12 ), a micronutrient synthesized exclusively by certain prokaryotes. Bacteria-mediated B 12 supply presents an important but poorly understood control on physiology and…
Park, Kim, Kim et al. · 2026 · Annals of hepato-biliary-pancreatic surgery
The optimal surgical approach for middle-third extrahepatic cholangiocarcinoma (MCC)-bile duct segmental resection (BDSR) or pancreaticoduodenectomy (PD)-remains controversial. This study aimed to compare the short- and long-term outcomes…
Shao, Feng, Yang et al. · 2026 · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
This study compared the incidence of adverse reactions following single versus simultaneous administration of the domestic diphtheria, tetanus and acellular pertussis combined vaccine (DTaP) after the immunization schedule adjustment in…
Du, Wu, Yang et al. · 2026 · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Dust mites (DM) are important allergens for allergic rhinitis (AR) and allergic asthma (AA). This study aims to analyze the component characteristics of dust mite-sensitized patients in Shenzhen and to explore the association between…
Liu, Hong, Yang et al. · 2026 · International dental journal
Traditional dental composite resins faced persistent challenges regarding biofilm accumulation and hydrolytic degradation. This study aimed to develop a novel resin monomer fluorinated polyurethane dimethacrylate (FPUDMA) and…
Li, Liu, Sun et al. · 2026 · American journal of translational research
To investigate the seroprevalence and risk factors of Toxoplasma gondii ( T. gondii ) infection in females with breast tumors in eastern China. This case-control study enrolled 610 breast tumor patients and 610 healthy controls. Serum…
Meicen, Wei, Yanai et al. · 2026 · Frontiers in endocrinology
Thyroid hormones play critical roles in regulating bone turnover and maintaining bone mass. However, the relationship among thyroid hormones, their sensitivity indices, bone mineral density (BMD) and fracture risk remained unclear in the…
Hu, Wei, An et al. · 2026 · iScience
Subterranean burrows of plateau zokors ( Eospalax baileyi ) on the Qinghai-Tibet Plateau become significantly colder and more hypoxic with increasing altitude. Because cholesterol biosynthesis is highly oxygen-intensive, it is typically…
Liu, Chen, Sun et al. · 2026 · Frontiers in psychology
Although the mental health benefits of horticultural therapy (HT) are well-established, the influence of intervention duration and the temporal dynamics of effects remain insufficiently explored, lacking evidence for optimal protocol…
Du, Zhang, Xu et al. · 2026 · Scientific reports
To evaluate the remediation strategies for newly reclaimed, heavily salinized farmland in Xinjiang province, China, a three-year field experiment was conducted comparing different treatments, such as agricultural improvement measures…
Li, Li, Xie et al. · 2026 · Pediatrics international : official journal of the Japan Pediatric Society
To explore the risk factors affecting Epstein-Barr virus (EBV) infection after pediatric liver transplantation (PLT) and analyze the survival outcomes of EBV infection in PLT. A retrospective analysis was conducted on clinical data from…
Xiong, Shali, Kadier et al. · 2026 · Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
To investigate the effectiveness of incorporating small gap anastomosis (SGA) and epineurial sheath tube (EST) sleeve coaptation into conventional targeted muscle reinnervation (TMR) for the treatment of post-amputation painful stump…
Sun, Yao, Gu et al. · 2026 · Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
To evaluate the effectiveness of using a bioinductive patch on tendon healing, functional recovery, and safety in arthroscopic rotator cuff repair. A non-concurrent controlled study with prospective enrollment of the intervention group and…
He, Li, Xiao et al. · 2026 · Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
To investigate the feasibility and effectiveness of uni-portal non-coaxial spinal endoscopic surgery (UNSES) via a single incision for the treatment of adjacent two-segmental lumbar disc herniation (LDH). A retrospective analysis was…
Khalid, Hussain, Ward Mitchell et al. · 2026 · Journal of neurosurgery
Approved in 1997, vagus nerve stimulation (VNS) is now a mainstay treatment of refractory epilepsy. While the safety and efficacy of this treatment modality are well established, the authors investigated the patient- and disease-related…
Abedinzade Zare, Vafadar, Behroozibakhsh et al. · 2026 · European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
This study aimed to compare the effect of water-based ammonia-free silver fluoride (SF) and silver diammine fluoride (SDF) on the microshear bond strength (MSBS) of resin-modified glass ionomer (RMGIC) to artificially demineralised primary…
Mokhtar, Gawish, Abdelgawad et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
To compare the clinical and radiological outcomes of anterior cruciate ligament reconstruction (ACLR) augmented with platelet-rich plasma (PRP) (1) or bone marrow aspirate concentrate (BMAC) (2) against a control group undergoing standard…
Wang, Wang, Shi et al. · 2026 · Frontiers in physiology
To investigate the association between hyperlipidemia lumbar disc degeneration (LDD) in patients hospitalized for low back pain. A total of 165 patients with hyperlipidemia hospitalized for low back pain (mean age…
Lertyongphati, Udomkhwamsuk, Amornrungrojanakul et al. · 2026 · Frontiers in sports and active living
In light of the growing global trend toward health awareness, wearable technologies like smartwatches have become essential for monitoring physiological indicators such as heart rate (HR). However, their utility faces two critical…