Negative / Null Result ReportOpen accessMedicine
Kawamoto S, Horiguchi H, Torigoe D et al. · 2026 · EMBO reports
The discovery of the senescence-associated secretory phenotype (SASP) has reshaped our understanding of cellular senescence, shifting its role from a solely tumor-suppressive mechanism to a potential driver of chronic inflammation and…
View details →DOI: 10.1038/s44319-026-00740-5 Negative / Null Result ReportOpen accessMedicine
Ağar ET, Yüksel C · 2026 · Journal of surgical case reports
The pyramidal lobe (PL) of the thyroid gland is a common embryological remnant; however, the presence of double PLs is an exceptionally rare anatomical variation. Failure to recognize this anomaly may result in incomplete thyroidectomy,…
View details →DOI: 10.1093/jscr/rjag049 Negative / Null Result ReportMedicine
Arega TW, Bricq S, Meriaudeau F · 2025 · Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
In real-world scenarios, medical image segmentation models encounter input images that may deviate from the training images in various ways. These differences can arise from changes in image scanners and acquisition protocols, or even the…
View details →DOI: 10.1016/j.compmedimag.2024.102476 Negative / Null Result ReportMedicine
Hsu AL, Wu CW, Huang CM et al. · 2025 · Journal of psychiatric research
Late-life depression (LLD) is a heterogeneous mental disorder with a high risk of suicide, often linked to abnormalities in brain networks, particularly the prefrontal cortex. While transcranial magnetic stimulation targeting the dorsal…
View details →DOI: 10.1016/j.jpsychires.2025.04.053 Negative / Null Result ReportOpen accessMedicine
Andová N, Repiská V, Priščáková P et al. · 2026 · Case reports in women's health
False-negative results in non-invasive prenatal testing are rare but clinically significant, particularly in the presence of biological factors such as feto-placental mosaicism. This report describes a pregnancy affected by fetal trisomy…
View details →DOI: 10.1016/j.crwh.2026.e00813 Negative / Null Result ReportOpen accessMedicine
Okuno-Ozeki N, Kohama Y, Taguchi H et al. · 2025 · Scientific reports
Reducing salt intake is crucial for managing hypertension. While efforts to reduce salt intake are based on the assumption that people have a preference for salt, it is also important to acknowledge that there is an aversion to high levels…
View details →DOI: 10.1038/s41598-025-09602-x Negative / Null Result ReportOpen accessMedicine
Eremichev R, Nikolaeva N, Khandokhin M et al. · 2025 · Biology
Recent discovery of menstruation in the Egyptian spiny mouse ( Acomys cahirinus) highlighted this species as a feasible model for the study of menstrual cycle physiology. However, reports on active menstrual bleeding in this animal were…
View details →DOI: 10.3390/biology14101365 Negative / Null Result ReportOpen accessMedicine
Yang R, Wang Y, Fu Q et al. · 2026 · BMJ open
Objectives To establish optimal pre-pregnancy body mass index (BMI)-specific gestational weight gain (GWG) ranges for twin pregnancies and compare their association with maternal and neonatal adverse outcomes against Institute of Medicine…
View details →DOI: 10.1136/bmjopen-2025-112189 Negative / Null Result ReportOpen accessMedicine
Saito A, Terai H, Kim TJ et al. · 2024 · Cancer medicine
Background Companion diagnostic tests play a crucial role in guiding treatment decisions for patients with non-small cell lung cancer (NSCLC). The Oncomine Dx Target Test (ODxTT) Multi-CDx System has emerged as a prominent companion…
View details →DOI: 10.1002/cam4.7077 Negative / Null Result ReportOpen accessMedicine
Awaly M, Norton M, Ahmed D et al. · 2025 · Cureus
Midline laparotomy remains essential in gynecological oncology, and rectus sheath catheters (RSCs) are commonly used for postoperative analgesia. We report the case of a 46-year-old woman who underwent midline laparotomy for a suspected…
View details →DOI: 10.7759/cureus.86892 Negative / Null Result ReportOpen accessMedicine
Salimkhanov R, Utkina M, Bagirova H et al. · 2025 · Frontiers in endocrinology
Multiple endocrine neoplasia type 1 (MEN-1; OMIM 131100) is a rare, autosomal dominant syndrome caused by heterozygous inactivating mutations in the MEN1 tumor suppressor gene (11q13; OMIM 613733). MEN-1 is characterized by polyglandular…
View details →DOI: 10.3389/fendo.2025.1662871 Negative / Null Result ReportOpen accessMedicine
Miquel-Rodríguez R, González-Toledo B, Pérez-Gómez MV et al. · 2024 · International journal of molecular sciences
Autosomal polycystic kidney disease (ADPKD) is the most common genetic form of kidney failure, reflecting unmet needs in management. Prescription of the only approved treatment (tolvaptan) is limited to persons with rapidly progressing…
View details →DOI: 10.3390/ijms25095036 Negative / Null Result ReportOpen accessMedicine
Vinyard DJ, Govindjee G · 2024 · Photosynthesis research
Photosystem II (PSII) uses light energy to oxidize water and to reduce plastoquinone in the photosynthetic electron transport chain. O 2 is produced as a byproduct. While most members of the PSII research community agree that O 2…
View details →DOI: 10.1007/s11120-024-01111-8 Negative / Null Result ReportOpen accessMedicine
Halalsheh H, Odeh N, Kiswani A et al. · 2026 · Cancers
Background Accurate staging is vital for optimizing outcomes in pediatric rhabdomyosarcoma (RMS). While [ 18 F]-FDG PET/CT is increasingly utilized, its specific impact on clinical management and its prognostic value compared to…
View details →DOI: 10.3390/cancers18101629 Failed Experiment ReportOpen accessMedicine
Tanglay O, Jhunjhnuwala D, Huynh W · 2025 · Frontiers in human neuroscience
Introduction Post-stroke cognitive impairment (PSCI) is common and often under-recognized, particularly in the acute phase. Most cognitive screening tools provide only a global score, overlooking domain-specific deficits that influence…
View details →DOI: 10.3389/fnhum.2025.1678230 Negative / Null Result ReportMedicine
Ito S, Takano C, Hoque SA et al. · 2025 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
The BioFire FilmArray® Gastrointestinal (GI) Panel, a widely used diagnostic tool, is designed to detect the genetic material of 22 common pathogens responsible for gastroenteritis, including viruses, bacteria, and parasites. It can detect…
View details →DOI: 10.1016/j.jiac.2025.102626 Negative / Null Result ReportOpen accessMedicine
Miao J, Xu Y, Qiao F et al. · 2026 · Oncology letters
The present prospective study aimed to investigate whether gallium-68-labeled fibroblast activation protein inhibitor-04 ( 68 Ga-FAPI-04) positron emission tomography (PET)/magnetic resonance imaging (MRI) could provide notably increased…
View details →DOI: 10.3892/ol.2026.15647 Negative / Null Result ReportOpen accessMedicine
Arcieri F, Vasta A, Sorrenti S et al. · 2026 · Journal of clinical medicine
Background: Congenital cytomegalovirus (cCMV) infection is a leading cause of neonatal morbidity. This retrospective study aimed to evaluate the efficacy of valacyclovir in reducing vertical transmission after primary maternal CMV…
View details →DOI: 10.3390/jcm15020809 Negative / Null Result ReportOpen accessMedicine
Shi J, Li G, Tang W et al. · 2026 · Frontiers in oncology
Adenocarcinoma originating from the anal gland with immunohistochemical expression of GATA3 and TTF-1 (ACAGGT) is a rare entity. This report describes an 80-year-old female patient who detected a perianal mass without an obvious cause 10…
View details →DOI: 10.3389/fonc.2026.1673646 Negative / Null Result ReportMedicine
K K V, P R A, Rao BK et al. · 2024 · Rapid communications in mass spectrometry : RCM
Rationale The exploration of the gut microbiome and related metabolites holds an exciting future in health science. The challenges associated with fecal sample testing are proper sample collection, sterile transportation, optimal transport…
View details →DOI: 10.1002/rcm.9923 Negative / Null Result ReportOpen accessMedicine
Burrows P, Brown RA, Samuelsen A et al. · 2025 · Antimicrobial stewardship & healthcare epidemiology : ASHE
Objective To assess whether antibiotic duration (AD) and one-year antibiotic-free days (AFD) are associated with key in-hospital and post-discharge outcomes among critically ill adults. Design Prospective observational study. Setting…
View details →DOI: 10.1017/ash.2025.10054 Negative / Null Result ReportOpen accessMedicine
Sun L, Jiang Y, Ma X et al. · 2026 · Frontiers in pharmacology
Background Currently, postoperative nonsteroidal anti-inflammatory drugs-associated kidney damage in hypertensive patients remains undetermined. This study aimed to examine renal safety of short-term post-surgery use of flurbiprofen axetil…
View details →DOI: 10.3389/fphar.2026.1773939 Negative / Null Result ReportOpen accessMedicine
Sachetto ATA, Mackman N · 2024 · Research and practice in thrombosis and haemostasis
Background Tissue factor (TF) is the primary cellular initiator of the blood coagulation cascade. Increased levels of TF expression on circulating monocytes or on extracellular vesicles (EVs) are associated with thrombosis in a variety of…
View details →DOI: 10.1016/j.rpth.2024.102325 Negative / Null Result ReportOpen accessMedicine
De Ryst JE, Bergström S, Mravinacova S et al. · 2026 · Fluids and barriers of the CNS
Background Aquaporin-4 (AQP4) is crucial for brain fluid regulation and glymphatic system function. Idiopathic normal pressure hydrocephalus (INPH) is characterized by impaired CSF flow and is treated with shunt surgery. This study…
View details →DOI: 10.1186/s12987-026-00809-2 Negative / Null Result ReportMedicine
Liu D, Yan Q, Qin X et al. · 2025 · Biochimica et biophysica acta. Bioenergetics
Photosystem I (PSI) is a large membrane photosynthetic complex that harvests sunlight and drives photosynthetic electron transport. In both green algae and higher plants, PSI's ultrafast energy transfer and charge separation kinetics have…
View details →DOI: 10.1016/j.bbabio.2024.149526 Negative / Null Result ReportOpen accessMedicine
S R S, Holla R, Rao M et al. · 2026 · The Indian journal of medical research
Background and objectives The gold standard for diagnosing malaria is peripheral smear. Histidine-rich protein 2 (HRP2)-based rapid diagnostic tests (RDTs) are particularly used for P. falciparum (pf) infections. These tests are easily…
View details →DOI: 10.25259/ijmr_2856_2025 Negative / Null Result ReportOpen accessMedicine
N R, Sivamani H, Sivaraman A et al. · 2024 · Cureus
This report presents the case of vaginal foreign body (FB) in a seven-year-old girl with recurrent genitourinary symptoms that went unrecognized for two years. Despite thorough evaluation including MRI, cystourethroscopy, and several…
View details →DOI: 10.7759/cureus.71259 Negative / Null Result ReportOpen accessMedicine
Zehner KM, Salib A, Sanchez JG et al. · 2026 · Journal of hand surgery global online
Purpose Carpal tunnel syndrome may be considered for carpal tunnel injection (CTI). Ultrasound (US) guidance has been proposed to improve CTI accuracy, but the trend across the years, factors associated with utilization, and outcomes are…
View details →DOI: 10.1016/j.jhsg.2026.100950 Negative / Null Result ReportOpen accessMedicine
Almutairi M, Alalmaee R, Alamer E et al. · 2026 · Journal of clinical tuberculosis and other mycobacterial diseases
Background Tuberculosis (TB) is a major global health issue, particularly among HIV-positive individuals. In Saudi Arabia, the incidence has declined to 8.4 per 100,000 but remains a concern among high-risk groups. Extrapulmonary TB,…
View details →DOI: 10.1016/j.jctube.2026.100603 Negative / Null Result Report
Zheng J, Zhou Y, Fuentes RJ et al. · 2024 · Preprint
The motor protein Prestin found in the outer hair cells (OHCs) of the inner ear is responsible for producing high sensitivity and sharp frequency selectivity for mammalian hearing. Some studies have suggested that Prestin could serve as a…
View details →DOI: 10.20944/preprints202405.0825.v1 