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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21252 results · page 167 of 709

Negative / Null Result Report

Lower body weight and increasing age are significant risk factors for complications following bi-oblique proximal ulnar osteotomy in dogs

Alan Danielski, Isabel de Marcos Carpio, Camilla Danielski et al. · 2023 · Journal of the American Veterinary Medical Association

Abstract OBJECTIVE To report and evaluate the risk factors for complications following bi-oblique proximal ulnar osteotomy (PUO) in dogs. ANIMALS 82 client-owned dogs (93 limbs). METHODS Clinical records of dogs treated with bi-oblique PUO…

View details →DOI: 10.2460/javma.23.05.0232Cited by 4
Negative / Null Result Report

Factitious thyrotoxicosis: how to find it

Pakaworn Vorasart, Chutintorn Sriphrapradang · 2019 · Diagnosis

Abstract Background Although the most common cause of thyrotoxicosis is Graves’ disease, the determination of the cause of thyrotoxicosis is important for establishing appropriate management. Diagnosis of surreptitious ingestion of thyroid…

View details →DOI: 10.1515/dx-2019-0015Cited by 4
Negative / Null Result Report

Uropathogenic Escherichia coli causes significant urothelial damage in an ex vivo porcine bladder model, with no protective effect observed from cranberry or d -mannose

Jenane Konesan, Kate H Moore, Kylie J Mansfield et al. · 2024 · Pathogens and Disease

Abstract Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), have an unclear impact on bladder mucosal physiology. This study investigates UPEC’s effects on the urothelium and lamina propria using an…

View details →DOI: 10.1093/femspd/ftae026Cited by 4
Negative / Null Result Report

Host Bloodmeal Source Has No Significant Effect on the Fecundity and Subsequent Larval Development Traits of the Progeny in Culicoides furens Poey (Diptera: Ceratopogonidae)

Dinesh Erram, Theodore Vincent Black, Nathan Burkett-Cadena · 2021 · Journal of Medical Entomology

Abstract Culicoides Latreille species (Diptera: Ceratopogonidae) are insects of significant medical and veterinary importance worldwide because their bites can cause major annoyance, allergic reactions, and/or pathogen transmission to…

View details →DOI: 10.1093/jme/tjab085Cited by 3
Negative / Null Result Report

Thalassemia and assisted reproduction: non-transfusion-dependent thalassemia shows no significant effect on live birth rates after embryo transfer

Li Fan, Liuyan Wei, Ni Tang et al. · 2025 · Frontiers in Cell and Developmental Biology

Background Thalassemia is a hereditary blood disorder that can impact fertility due to various factors such as iron overload and endocrine disruption. While the effects of iron overload on fertility outcomes in transfusion-dependent…

View details →DOI: 10.3389/fcell.2025.1573572Cited by 3
Negative / Null Result Report

Comparison of the Kinematics Following Gait Perturbation in Individuals Who Did or Did Not Undergo Total Knee Replacement

Vicktoria Elkarif, Leonid Kandel, Debbie Rand et al. · 2021 · Applied Sciences

We aimed to compare the spatiotemporal parameters and joint kinematics during unperturbed and perturbed gait between individuals with osteoarthritis (OA) who did or did not undergo total knee replacement (TKR) one year post a baseline…

View details →DOI: 10.3390/app11167453Cited by 3
Negative / Null Result Report

Deuterium-depletion has no significant impact on the mutation rate of Escherichia coli, deuterium abundance therefore has a probabilistic, not deterministic effect on spontaneous mutagenesis

Walliyulahi Ajibola, Ildikó Karcagi, Gábor Somlyai et al. · 2021 · PLOS ONE

Deuterium (D), the second most abundant isotope of hydrogen is present in natural waters at an approximate concentration of 145–155 ppm (ca. 1.5E-4 atom/atom). D is known to influence various biological processes due to its physical and…

View details →DOI: 10.1371/journal.pone.0243517Cited by 3
Negative / Null Result Report

Short message service cancellation intervention to reduce integrated sexual health and HIV ‘did not attend’ appointment rates

Andrew Tomkins, Sam Naylor, Emile Morgan · 2018 · International Journal of STD & AIDS

Did not attend (DNA) appointments create a significant impact upon resource and finance efficiency in the NHS. Despite introduction of short-message service (SMS) reminders to our patients, DNA rates remained persistently high. An option…

View details →DOI: 10.1177/0956462418804656Cited by 3
Negative / Null Result Report

Climate change impact on the degradation of historically significant wooden furniture in a cultural heritage building in Vestfold, Norway

Petros Choidis, Akriti Sharma, Giulia Grottesi et al. · 2022 · E3S Web of Conferences

Climate change is expected to significantly affect the interior climate of old, leaky buildings without HVAC systems. As a result, the items of cultural significance that are hosted indoors will experience new ambient conditions, which…

View details →DOI: 10.1051/e3sconf/202236211003Cited by 3
Negative / Null Result Report

The Identification of Significant Single Nucleotide Polymorphisms for Shoot Sulfur Accumulation and Sulfur Concentration Using a Genome-Wide Association Analysis in Wild Soybean Seedlings

Hui Wang, Yu’e Zhang, Yudan Chen et al. · 2024 · Agronomy

To understand the genetic basis of soybean sulfur utilization, a genome-wide association study (GWAS) and transcriptome analysis were used to discover new sulfur utilization genes in 121 wild soybeans. The shoot sulfur accumulation (SA)…

View details →DOI: 10.3390/agronomy14020292Cited by 3
Negative / Null Result Report

Implementing employability strategy: Inspiring change through significant conversations

Bonnie Amelia Dean, Kate Tubridy, Michelle J Eady et al. · 2024 · Journal of Teaching and Learning for Graduate Employability

Higher education plays a key role in cultivating graduate employability, which is essential to meeting multiple individual, community, social and labour market needs. Universities prioritise employability through strategic goals and…

View details →DOI: 10.21153/jtlge2024vol15no2art2021Cited by 3
Negative / Null Result Report

Prothrombotic Factors Have Significant Association with Arterial and Venous Strokes in Indian Tamilians

Sunil Narayan, Adithan Chandrasekaran, Debdatta Basu et al. · 2020 · The Journal of Applied Laboratory Medicine

Abstract Background Prothrombotic factors have been correlated with vascular events in young patients, with recurrent strokes, and with venous thromboembolisms. However, their prevalence in adult strokes, in healthy populations, and in…

View details →DOI: 10.1093/jalm/jfaa198Cited by 3
Negative / Null Result Report

Did the ERAS Protocol Improve Our Results in Locally Advanced Gastric Cancer Surgery?

Özgül Düzgün, Pırıltı Özcan, Mehmet Faik Özçelik · 2022 · Journal of Personalized Medicine

ERAS is a protocol consisting of multidisciplinary approaches, including patient education, fluid resuscitation, keeping patients’ innormothermic state, early feeding, and mobilization. We aimed to present and compare the postoperative…

View details →DOI: 10.3390/jpm12101549Cited by 3
Negative / Null Result Report

Addition of an online, validated family history questionnaire to the Dutch FIT-based screening programme did not improve its diagnostic yield

Victorine H. Roos, Frank G. J. Kallenberg, Manon van der Vlugt et al. · 2020 · British Journal of Cancer

Abstract Background Faecal immunochemical testing (FIT) is suboptimal in detecting advanced neoplasia (AN). To increase the sensitivity and yield of a FIT-based screening programme, FIT could be combined with risk factors for AN. We…

View details →DOI: 10.1038/s41416-020-0832-8Cited by 3
Negative / Null Result Report

Increased recurrent risk did not improve cerebrovascular disease survivors’ response to stroke in China: a cross-sectional, community-based study

Shengde Li, Li-Ying Cui, Craig Anderson et al. · 2020 · BMC Neurology

Abstract Background Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able to…

View details →DOI: 10.1186/s12883-020-01724-1Cited by 3
Negative / Null Result Report

Significant association of hyperandrogenism and insulin resistance with the epigenetic alterations in PPARG1 gene in granulosa cells of PCOS females

Zahra Dashti, Vahid Razban, Jafar Fallahi et al. · 2025 · Egyptian Journal of Medical Human Genetics

Abstract Background Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine and metabolic disorders, affecting approximately 15% of females. This syndrome is characterized by its remarkable heterogeneity, and epigenetic…

View details →DOI: 10.1186/s43042-025-00731-6Cited by 3
Negative / Null Result Report

Beaver dam analogs did not improve beaver translocation outcomes in a desert river

Christine Sandbach, Julie K. Young, Mary Conner et al. · 2024 · Restoration Ecology

Stream restoration programs employ beaver‐related restoration techniques, including beaver translocations and installation of beaver dam analogs (BDA), to create complex in‐stream habitat. We investigated whether BDA installations improved…

View details →DOI: 10.1111/rec.14107Cited by 3
Negative / Null Result Report

Implementation of electronic charting is not associated with significant change in physician productivity in an academic emergency department

Dusadee Sarangarm, Gregory Lamb, Steven Weiss et al. · 2018 · JAMIA Open

Abstract Objectives To compare physician productivity and billing before and after implementation of electronic charting in an academic emergency department (ED). Materials and methods This retrospective, blinded, observational study…

View details →DOI: 10.1093/jamiaopen/ooy022Cited by 3
Negative / Null Result Report

Man vs. machine: can AI outperform ESL student translations?

Anas Alkhofi · 2025 · Frontiers in Artificial Intelligence

This study compares the quality of English-to-Arabic translations produced by Google Translate (GT) with those generated by student translators. Despite advancements in neural machine translation technology, educators often remain…

View details →DOI: 10.3389/frai.2025.1624754Cited by 3
Negative / Null Result Report

Evaluating a peer-led wellbeing programme for doctors-in-training during the COVID-19 pandemic in Victoria, Australia, using the Most Significant Change technique

Karen Crinall, Madeleine Ward, Rebecca McDonald et al. · 2022 · Evaluation Journal of Australasia

This article discusses the use of the Most Significant Change (MSC) technique in a mixed-methods evaluation of a pilot wellbeing programme for obstetrics and gynaecology doctors-in-training introduced at a large public hospital during…

View details →DOI: 10.1177/1035719x221080576Cited by 3
Negative / Null Result Report

Use of the most significant change technique to evaluate intervention in promoting childbirth spacing in Nigeria

Adolor Aisiri, Babafunke Fagbemi, Oluseyi A. Akintola et al. · 2020 · African Evaluation Journal

Background: Childbirth spacing (CBS) or Family Planning (FP) methods are considered an essential component of sexual and reproductive health. It refers to the resting period between pregnancies that provides the mother with time to…

View details →DOI: 10.4102/aej.v8i1.426Cited by 3
Negative / Null Result Report

Investigation of association between clinically significant prostate cancer, obesity and platelet to-lymphocyte ratio and neutrophil -to-lymphocyte ratio

Johanna Dahan, Jehonathan Pinthus, Guila Delouya et al. · 2024 · BMC Urology

Abstract Introduction Several blood markers of inflammation are elevated in prostate cancer (PCa) and have prognostic value. Little is known about the relationship between these markers, PCa, and other factors associated with chronic…

View details →DOI: 10.1186/s12894-024-01617-2Cited by 3
Negative / Null Result Report

Lack of significant association between selected STAT3 polymorphisms and rheumatoid arthritis in the Polish population

Barbara Stypińska, Marzena Olesińska, Andrzej Pawlik et al. · 2018 · Rheumatology

Objectives Rheumatoid arthritis (RA) is the most common systemic inflammatory disease and is of unknown etiology. The altered balance between immunosuppressive and inflammatory T cell subpopulations exerts a huge impact on RA pathogenesis.…

View details →DOI: 10.5114/reum.2018.75517Cited by 3
Negative / Null Result Report

Inferring The Cost Of Equity: Does The CAPM Consistently Outperform The Income And Multiples Valuation Models?

Vusani Moyo, Fidelis Mache · 2018 · Journal of Applied Business Research (JABR)

A number of surveys reveal that a large number of analysts, valuation experts, investors, chief financial officers and finance academics employ the capital asset pricing model (CAPM) of Sharpe (1962) and Lintner (1965) to estimate the cost…

View details →DOI: 10.19030/jabr.v34i3.10174Cited by 3