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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21252 results · page 168 of 709

Methods Dead-End

Lack of Significant Association between Plasma/Serum miR‐221 Expression and Poor Survival of Carcinoma: A Meta‐Analysis

Min-hua Rong, Yi-wu Dang, Gang Chen · 2013 · The Scientific World Journal

Background . MicroRNAs (miRNAs) exhibit altered expression levels in cancers, and they may play a potential role as diagnostic and prognostic biomarkers of cancers. The aim of this meta‐analysis was to summarize recent advances in miR‐221…

View details →DOI: 10.1155/2013/394030Cited by 3
Negative / Null Result Report

Do Large Datasets or Hybrid Integrated Models Outperform Simple Ones in Predicting Commodity Prices and Foreign Exchange Rates?

Jin Shang, Shigeyuki Hamori · 2023 · Journal of Risk and Financial Management

With the continuous advancement of machine learning and the increasing availability of internet-based information, there is a belief that these approaches and datasets enhance the accuracy of price prediction. However, this study aims to…

View details →DOI: 10.3390/jrfm16060298Cited by 3
Negative / Null Result Report

Forecasting stock returns on the Amman Stock Exchange: Do neural networks outperform linear regressions?

Abdel Razzaq Al Rababa’a, Zaid Saidat, Raed Hendawi · 2021 · Investment Management and Financial Innovations

Different models have been used in the finance literature to predict the stock market returns. However, it remains an open question whether non-linear models can outperform linear models while providing accurate predictions for future…

View details →DOI: 10.21511/imfi.18(4).2021.24Cited by 3
Negative / Null Result Report

Strategically creating maximally heterogeneous lab groups did not improve group performance in an introductory biology lab class

Anisha S. Navlekar, Elli J. Theobald, Ken Griffith et al. · 2025 · PLOS One

Collaboration is a critical skill for professionals in any field to master, and group work is a prominent component of many lab courses. However, there is conflicting guidance about the best method for forming groups to maximize…

View details →DOI: 10.1371/journal.pone.0323799Cited by 3
Negative / Null Result Report

Do Fractals Confirm the General Theory of Relativity?

Irina Rozgacheva · 2019 · Symmetry

The relatively high abundance of fractal properties of complex systems on Earth and in space is considered an argument in support of the general relativity of the geometric theory of gravity. The fractality may be called the fractal…

View details →DOI: 10.3390/sym11060740Cited by 3
Negative / Null Result Report

Flexing to outperform: workforce differentiation, HR flexibility and firm performance

Paula Apascaritei, Marta M. Elvira, María Rodríguez-García · 2024 · International Journal of Manpower

Purpose Resource orchestration theory proposes that firms need resources, capabilities, and horizontal and vertical alignment to achieve high performance. Thus, we investigate which combinations of horizontal fit of resources…

View details →DOI: 10.1108/ijm-02-2024-0146Cited by 3
Negative / Null Result Report

Deriving significant factors for managing change in UN

James Wan, Raafat Saade, Ling Wang · 2019 · Journal of Organizational Change Management

Purpose A consequence of the UN general assembly resolution calling for increased efficiency and better utilization of resources in all its agencies, is a mandate for change. As a response to this resolution, the purpose of this paper is…

View details →DOI: 10.1108/jocm-10-2018-0288Cited by 3
Negative / Null Result Report

Preoperative walking intervention did not appear to improve patient-reported postoperative recovery in older adults with frailty traits: Randomized trial

Hammad Sadiq, Sanjeev Rampam, Jay Patel et al. · 2022 · Medicine

Objectives: To assess the impact of a preoperative walking intervention on improving postoperative recovery in at-risk frail older adult patients. Study Type: Unblinded, randomized controlled trial which assigned patients to intervention…

View details →DOI: 10.1097/md.0000000000030689Cited by 3
Negative / Null Result Report

Virtual Reality-Assisted, Single-Session Exposure for Public Speaking Anxiety: Improved Self-Reports and Heart Rate but No Significant Change in Heart Rate Variability

Tonia-Flery Artemi, Thekla Konstantinou, Stephany Naziri et al. · 2025 · Virtual Worlds

Introduction: This study examines the combined use of objective physiological measures (heart rate [HR], heart rate variability [HRV]) and subjective self-reports to gain a comprehensive understanding of anxiety reduction…

View details →DOI: 10.3390/virtualworlds4020027Cited by 3
Negative / Null Result Report

Where Did the Y Chromosome in the Spiny Rat Go, and How Did It Get There?

Miki Okuno, Kentaro Matsuoka, Yuta Mochimaru et al. · 2025 · Molecular Biology and Evolution

Abstract The XX/XY sex chromosome system is highly conserved across mammals, with rare exceptions where males lack a Y chromosome. Among these is the genus Tokudaia, a group of spiny rats comprising three species with unique sex chromosome…

View details →DOI: 10.1093/molbev/msaf102Cited by 3
Negative / Null Result Report

Climate change - mediated atmospheric 210Po and 210Pb distribution: How significant can it be for the inhalation dose to humans?

Saif Uddin, Aysun U. Gorgun, Scott W. Fowler et al. · 2023 · Journal of Environmental Exposure Assessment

The concentration of 210Po and 210Pb in vegetation, and their transfer from soil to vegetation and via aerosol deposited on foliage are well established. The available data show significantly higher levels of these radionuclides in ash…

View details →DOI: 10.20517/jeea.2023.36Cited by 3
Abandoned Hypothesis

How Did Life Emerge in Chemically Complex Messy Environments?

Kenji Ikehara · 2022 · Life

One of the problems that make it difficult to solve the mystery of the origin of life is determining how life emerged in chemically complex messy environments on primitive Earth. In this article, the “chemically complex messy environments”…

View details →DOI: 10.3390/life12091319Cited by 3
Negative / Null Result Report

Did the accuracy of oral amoxicillin dosing of children improve after British National Formulary dose revisions in 2014? National cross-sectional survey in England

Olivia Rann, Mike Sharland, Paul Long et al. · 2017 · BMJ Open

Objectives Inaccurate antibiotic dosing can lead to treatment failure, fuel antimicrobial resistance and increase side effects. The British National Formulary for Children (BNFC) guidance recommends oral antibiotic dosing according to age…

View details →DOI: 10.1136/bmjopen-2017-016363Cited by 3
Negative / Null Result Report

Significant Temporal Association of Esophageal Air Events (Supragastric Belches, Air Swallows, and Gastric Belches) With Hiccups

Frederick W. Woodley, Kent Williams, Carlo Di Lorenzo et al. · 2022 · JPGN Reports

We previously reported our ability to objectively assess the strength of temporal relationships between gastroesophageal reflux (GER) disease‐like symptoms with esophageal air events (EAEs) (air swallows, gastric belching, and supragastric…

View details →DOI: 10.1097/pg9.0000000000000209Cited by 3
Negative / Null Result Report

Implementation of significant mental health service change: perceptions and concerns of a mental health workforce in the context of transformation

Margaret Glogowska, Melissa Stepney, Stephen Rocks et al. · 2022 · Journal of Health Organization and Management

Purpose As part of an evaluation of the nationally mandated Child and Adolescent Mental Health Services (CAMHS) “transformation” in one foundation NHS trust, the authors explored the experiences of mental health staff involved in the…

View details →DOI: 10.1108/jhom-06-2021-0205Cited by 3
Negative / Null Result Report

Do ETFs outperform CEFs in fixed income investing?

C. Edward Chang, Thomas M. Krueger, H. Doug Witte · 2015 · American Journal of Business

Purpose – For a number of reasons ranging from their more recent introduction to their perceived lesser excitement relative to stock-based peers, there have been few studies of fixed income (mainly bond) exchange-traded funds (ETFs). The…

View details →DOI: 10.1108/ajb-04-2015-0013Cited by 3
Negative / Null Result Report

Why Do Tree Ensemble Approximators Not Outperform the Recursive-Rule eXtraction Algorithm?

Soma Onishi, Masahiro Nishimura, Ryota Fujimura et al. · 2024 · Machine Learning and Knowledge Extraction

Although machine learning models are widely used in critical domains, their complexity and poor interpretability remain problematic. Decision trees (DTs) and rule-based models are known for their interpretability, and numerous studies have…

View details →DOI: 10.3390/make6010031Cited by 3
Negative / Null Result Report

Mean resolvent operator of a statistically steady flow

Colin Leclercq, Denis Sipp · 2023 · Journal of Fluid Mechanics

This paper introduces a new operator relevant to input–output analysis of flows in a statistically steady regime far from the steady base flow: the mean resolvent ${{\boldsymbol{\mathsf{R}}}}_0$ . It is defined as the operator predicting,…

View details →DOI: 10.1017/jfm.2023.530Cited by 3
Negative / Null Result Report

Long-Term Cognitive Outcomes After Surgery and Anesthesia: What We Find Depends on Where We Look

Hyundeok Joo, Laura Y. Li, Elizabeth L. Whitlock · 2023 · Current Anesthesiology Reports

Abstract Purpose of Review To review how anecdote and narrative medicine, primary cohort studies, epidemiological studies, and the dementia literature can be bridged to understand long-term postoperative cognitive decline. Recent Findings…

View details →DOI: 10.1007/s40140-023-00590-0Cited by 3
Negative / Null Result Report

A New Rymon Tree Based Procedure for Mining Statistically Significant Frequent Itemsets

Predrag Stanisic, Savo Tomovic · 2010 · International Journal of Computers Communications & Control

In this paper we suggest a new method for frequent itemsets mining, which is more efficient than well known Apriori algorithm. The method is based on special structure called Rymon tree. For its implementation, we suggest modified…

View details →DOI: 10.15837/ijccc.2010.4.2515Cited by 3
Negative / Null Result Report

Feeding concentrate pellets to early-lactation cows consuming spring ryegrass pasture did not reduce methane emissions

K. Garrett, E. Stubbs, E. Minnee et al. · 2025 · Animal Production Science

Context Feed additives containing methane-reducing compounds are effective where dairy cows are fed a total mixed ration. In pasture-based systems, there are challenges incorporating feed additives into the diet, although one potential…

View details →DOI: 10.1071/an25184Cited by 3
Negative / Null Result Report

Hydrochar did not reduce rice paddy NH3 volatilization compared to pyrochar in a soil column experiment

Xiaoyu Liu, Yueqin Cheng, Yang Liu et al. · 2020 · Scientific Reports

Abstract Pyrochar (PC) is always with high pH value, and improper application might increase rice paddy ammonia volatilization (PAV), which is the main nitrogen loss through air during rice production. Differently, hydrochar (HC) takes the…

View details →DOI: 10.1038/s41598-020-76213-zCited by 3
Negative / Null Result Report

Setting-aside cropland did not reduce greenhouse gas emissions from a drained peat soil in Sweden

Hannes Keck, Katharina H. E. Meurer, Sabine Jordan et al. · 2024 · Frontiers in Environmental Science

In the process of their formation, northern peatlands were accumulating vast amounts of carbon (C). When drained for agricultural use, a large proportion of that C is oxidized and emitted as carbon dioxide (CO 2 ), turning those peatlands…

View details →DOI: 10.3389/fenvs.2024.1386134Cited by 3