A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21697 results · page 146 of 724
Ching-Yi Lai, Kai-Min Chung · 2018 · Quantum Information and Computation
Homomorphic encryption is an encryption scheme that allows computations to be evaluated on encrypted inputs without knowledge of their raw messages. Recently Ouyang et al. constructed a quantum homomorphic encryption (QHE) scheme for…
Leonardo Calza, Isabella Bon, Marco Borderi et al. · 2020 · JAIDS Journal of Acquired Immune Deficiency Syndromes
Calza, Leonardo MD; Bon, Isabella PhD; Borderi, Marco MD; Colangeli, Vincenzo MD; Viale, Pierluigi MD Author Information
Uraiwan Buatoom, Muhammad Usman Jamil · 2023 · Applied Sciences
In image classification, various techniques have been developed to enhance the performance of principal component analysis (PCA) dimension reduction techniques with guiding weighting features to remove redundant and irrelevant features.…
Nathan Leggett, Nicole A. Thomas, Michael E. R. Nicholls · 2015 · Cognition & Emotion
Approach motivation leads to greater left hemisphere activation, whereas an avoidant motivational state activates the right hemisphere. Recent research, which served as the basis for the current experiment, suggests line bisection provides…
Katherine A. Rawson, Kathryn T. Wissman, Kalif E. Vaughn · 2015 · Journal of Experimental Psychology Learning Memory and Cognition
Recent research on testing effects (i.e., practice tests are more effective than restudy for enhancing subsequent memory) has focused on explaining when and why testing enhances memory. Of particular interest for present purposes, Zaromb…
Enzo M. Scutigliani, Edwin R. Scholl, Anita E. Grootemaat et al. · 2018 · Frontiers in Microbiology
Tuberculosis is once again a major global threat, leading to more than 1 million deaths each year. Treatment options for tuberculosis patients are limited, expensive and characterized by severe side effects, especially in the case of multi-drug resistant forms. Uncovering novel vulnerabilities of the pathogen is crucial to generate new therapeutic strategies. Using high resolution microscopy techniques, we discovered one such vulnerability of Mycobacterium tuberculosis. We demonstrate that the DNA of M. tuberculosis can condense under stressful conditions such as starvation and antibiotic trea
Anne Gast, Jasmin Richter, Borys Ruszpel · 2019 · Cognition & Emotion
In three experiments we investigated whether memory-independent evaluative conditioning (EC) and other memory-independent contingency learning (CL) effects occur in the valence contingency task (VCT). In the VCT, participants respond to…
Sarah N. Rigby, Lorna S. Jakobson, Pauline M. Pearson et al. · 2020 · Frontiers in Psychology
Alexithymia is a personality trait characterized by difficulties identifying and describing feelings (DIF and DDF) and an externally-oriented thinking style (EOT). The primary aim of the present study was to investigate links between alexithymia and the evaluation of emotional scenes. We also investigated whether viewers’ evaluations of emotional scenes were better predicted by specific alexithymic traits or by individual differences in sensory processing sensitivity (SPS). Participants (N = 106) completed measures of alexithymia and SPS along with a task requiring speeded judgments of the ple
Yi‐Ping Phoebe Chen, Ulrich Kirk, Suzanne Dikker · 2022 · Frontiers in Psychology
In recent years, the possible benefits of mindfulness meditation have sparked much public and academic interest. Mindfulness emphasizes cultivating awareness of our immediate experience and has been associated with compassion, empathy, and various other prosocial traits. However, neurobiological evidence pertaining to the prosocial benefits of mindfulness in social settings is sparse. In this study, we investigate neural correlates of trait mindful awareness during naturalistic dyadic interactions, using both intra-brain and inter-brain measures. We used the Muse headset, a portable electroenc
Todd W. Arnold, Alan D. Afton, Michael J. Anteau et al. · 2017 · Journal of Wildlife Management
ABSTRACT We recently analyzed long‐term (1951–2011) continental band‐recovery data from lesser scaup ( Aythya affinis ) and demonstrated that harvest rates declined through time, but annual survival rates exhibited no such trends;…
Tonia C. Carter, Scott J. Hebbring, Jixia Liu et al. · 2017 · Journal of Medical Virology
Host response to influenza is highly variable, suggesting a potential role of host genetic variation. To investigate the host genetics of severe influenza in a targeted fashion, 32 single nucleotide polymorphisms (SNPs) within viral immune…
Sera Wiechert, Leonie Hannah Shoshana Loewy, Ineke Wessel et al. · 2023 · Memory
Post-traumatic stress disorder is characterised by recurring memories of a traumatic experience despite deliberate attempts to forget (i.e., suppression). The Think/No-Think (TNT) task has been used widely in the laboratory to study…
Taeyong Kwon, Jessie D. Trujillo, Mariano Carossino et al. · 2025 · Emerging Microbes & Infections
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching 17 states and at least 1000 dairy herds in the United States. Subsequently, spillovers of the…
Muhammad Jasim Uddin, Willy W. Suen, Angela M. Bosco‐Lauth et al. · 2016 · Veterinary Research
West Nile virus (WNV) is one of the most common causes of epidemic viral encephalitis in horses worldwide. Peripheral blood mononuclear cells (PBMCs) are amongst the first to encounter the virus following a mosquito bite. This study aimed to elucidate the transcription kinetics of cytokine, Toll-like receptor (TLRs) and TLRs-associated genes following WNV challenge of equine PBMCs. PBMCs were challenged with an Australian strain of WNV (WNVNSW2011) and transcriptomes were quantified at 2, 6, 12 and 24 h post-infection (pi) using qRT-PCR. Type I and II interferons (IFNα, β and γ) mRNA transcrip
Anne Kopp, Alexandra Hübner, Florian Zirkel et al. · 2019 · Viruses
. Orthobunyaviruses and pacuviruses are mainly transmitted by blood-feeding insects and infect a variety of vertebrates whereas herbeviruses and shangaviruses have a host range restricted to insects. Here, we tested mosquitoes from a tropical rainforest in Mexico for infections with peribunyaviruses. We identified and characterized two previously unknown viruses, designated Baakal virus (BKAV) and Lakamha virus (LAKV). Sequencing and de novo assembly of the entire BKAV and LAKV genomes revealed that BKAV is an orthobunyavirus and LAKV is likely to belong to a new genus. LAKV was almost equidis
Massimo Salgaro · 2015 · Scientific Study of Literature
In literary theory, there are two common proposals about the nature of literature: that literariness is a distinctive characteristic of literary texts and that literariness is mostly characterized by highly foregrounded textual features.…
Robert Massey, Yu Chen, Marina Panova‐Noeva et al. · 2024 · Cardiovascular Diabetology
BACKGROUND: BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been lacking. Furthermore, it is not known whether BMI variability has an effect independent of HbA1c variability. METHODS: We investigated the association between BMI variability and 3P-MACE risk in the Harmony Outcomes trial (n = 9198), and further analysed placebo arms of REWIND (n = 4440) and EMPA-REG OUTCOME (n = 2333) trials, followed by real-world data from the Tayside Bioreso
Johan Jirholt, Bengt Åsling, Paul Hammond et al. · 2011 · PLoS ONE
Gastro-esophageal reflux disease (GERD) is partly caused by genetic factors. The underlying susceptibility genes are currently unknown, with the exception of COL3A1. We used three independent GERD patient cohorts to identify GERD susceptibility genes. Thirty-six families, demonstrating dominant transmission of GERD were subjected to whole genome microsatellite genotyping and linkage analysis. Five linked regions were identified. Two families shared a linked region (LOD 3.9 and 2.0) on chromosome 16. We used two additional independent GERD patient cohorts, one consisting of 219 trios (affected
Ornella Zollo, Neal Sondheimer · 2017 · Transcription
In vitro studies of mitochondrial transcription often use linear templates that fail to replicate key features of transcription on a circular genome. We developed a plasmid-based system for the analysis of heavy-strand promoters that…
James Alex Bonus, Judy Watts, C. Joseph Francemone · 2022 · Journal of Communication
Abstract Integrating predictions derived from the self-memory system and biographic resonance theory, the current project investigated the relationship between media-induced reminiscence and appreciation. In two experiments, undergraduates…
Pilar Fernández‐Martín, Rocío Rodríguez‐Herrera, Rosa Cánovas et al. · 2023 · European Child & Adolescent Psychiatry
In the past two decades, the traditional nosology of attention-deficit/hyperactivity disorder (ADHD) has been criticized for having insufficient discriminant validity. In line with current trends, in the present study, we combined a data-driven approach with the advantages of virtual reality aiming to identify novel behavioral profiles of ADHD based on ecological and performance-based measures of inattention, impulsivity, and hyperactivity. One hundred and ten Spanish-speaking participants (6-16 years) with ADHD (medication-naïve, n = 57) and typically developing participants (n = 53) complete
Jeremiasz Jagiełła, Efthimios Dardiotis, Jerzy Gąsowski et al. · 2014 · Neurologia i Neurochirurgia Polska
BACKGROUND AND PURPOSE: Spontaneous intracerebral haemorrhage (ICH) is the most fatal form of stroke with the highest morbidity and disability rate of all stroke types. Recent data suggest that the genetic background has a sizeable and…
James W. Price · 2014 · Journal of Addictive Diseases
Although the decriminalization of recreational marijuana and medical marijuana laws provide a compassionate answer for treatment-related issues in patients' lives, they leave questions open as to the impact on other realms of life, such as…
Tyler Colasante, Katie Faulkner, Dana Kharbotli et al. · 2024 · Affective Science
Abstract Public discourse and empirical studies have predominantly focused on the negative repercussions of social media on adolescents’ mental health. However, pervasive social media use is a relatively new phenomenon—its apparent harms have been widely accepted before sufficient longitudinal and experimental research has been conducted. The present study used an intensive longitudinal design (four assessments/day × 14 days; N = 154 12- to 15-year-olds ( M age = 13.47, SD = 0.58); N = 6,240 valid measurement occasions) to test the directionality of social media–negative emotion links in early
James P. Reynolds, Milica Vasiljevic, Mark Pilling et al. · 2020 · International Journal of Environmental Research and Public Health
Public support for numerous obesity policies is low, which is one barrier to their implementation. One reason for this low support is the tendency to ascribe obesity to failings of willpower as opposed to the environment. Correlational evidence supports this position. However, the experimental evidence is mixed. In two experimental studies, participants were randomised to receive no message, messages about the environment’s influence on obesity (Study 1 & 2), or messages about the environment’s influence on human behaviour (Study 1). We investigated whether communicating these messages cha
Giannis Penloglou, Alexandros Pavlou, Costas Kiparissides · 2023 · Fermentation
The intended circular economy for plastics envisages that they will be partially replaced by bio-based polymers in the future. In this work, the natural polyester polyhydroxybutyrate (PHB) was produced by Azohydromonas lata using cheese…
Serkan Biyik, Murat Aydin · 2026 · Journal of Electronic Materials
Abstract In this study, the arc-erosion performances of AgSnO 2 -based electrical contact materials containing different amounts of titanium dioxide (TiO 2 ) were investigated using the mechanical alloying-assisted powder metallurgy method. For this purpose, composite powder synthesis was carried out through grinding experiments using a planetary ball mill, and the produced composite powders were subjected to molding and vacuum sintering processes. Subsequently, electrical wear tests were carried out under inductive loads to investigate the arc-erosion performance of composites. Scanning elect
Hubert Krukowski, Sophie Valkenburg, A. Vich Vila et al. · 2026 · Nature Microbiology
Despite recent progress, microbial associations reported in chronic kidney disease (CKD) remain inconsistent. Here we combined quantitative faecal metagenomics (n = 130) and cross-study biomarker comparisons (ntotal = 4,420) to study…
Maria Staudinger, Anna Herzog, Ralf Loritz et al. · 2025 · Hydrology and earth system sciences
Abstract. It is widely assumed that data-driven models achieve good results only with sufficiently large training data, whereas process-based models are usually expected to be superior in data-poor situations. To investigate this, we calibrated several process-based and data-driven hydrological models using training datasets of observed discharge that differed in terms of both the number of data points and the type of data selection, allowing us to make a systematic comparison of the learning behaviour of the different model types. Four data-driven models (conditional probability distributions
Yangfan Lu, Sareer Ahmad, Shaista Noureen et al. · 2025 · Humanities and Social Sciences Communications
Renewable energy, technology, and innovation are central to sustainable development, but their effects vary by country because of institutional and economic differences. Previous studies often ignore these differences. By incorporating…