A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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Sean Haimowitz, David Cohen, Aatin K. Dhanda et al. · 2022 · The Laryngoscope
OBJECTIVES: Mucosal melanoma (MM) is a rare malignancy that can present in the head and neck (H&N). The Oral cavity is the second most common primary site in the H&N after sinonasal mucosa. This study investigates the impact of demographic…
Andrew Goudie, Douglas H.J. Elder, Harshal Deshmukh et al. · 2014 · European Journal of Heart Failure
BACKGROUND: The use of oral anticoagulation in patients with heart failure in sinus rhythm remains controversial as previous large randomized controlled trials (RCTs) have not shown a survival benefit. However, heterogeneity exists among…
Sidsel Pedersen, Søren Møller, Marco Donia et al. · 2022 · Melanoma Research
Novel medical therapies have revolutionized outcome for patients with melanoma. However, patients with melanoma brain metastases (MBM) still have poor survival. Data are limited as these patients are generally excluded from clinical…
Fangzheng Wang, Jiang Chuner, Quanquan Sun et al. · 2018 · Journal of Cancer
In this study, we examined whether combining neoadjuvant chemotherapy (NAC) and/or concurrent chemotherapy (CC) with intensity-modulated radiotherapy (IMRT) improved survival in patients with stage II nasopharyngeal carcinoma (NPC). Two hundred forty-two stage II NPC patients were enrolled between May 2008 and April 2014 and received radical IMRT with simultaneous integrated boost technique using 6 MV photons; some patient groups also received chemotherapy every 3 weeks for 2-3 cycles. The median follow-up duration was 69 months for all patients. At the last follow-up, 18 patients had experien
R Karkee · 2012 · Journal of Nepal Medical Association
Nepal reportedly reduced the maternal mortality ratio by 48% within one decade between 1996-2005 and received the Millennium development goal award for this. However, there is debate regarding the accuracy of this figure. On the basis of…
Ananda Chairunnisa, Zuliani Dalimunthe · 2021 · Jurnal Akuntansi dan Keuangan
In Indonesia's capital market, there was a phenomenon that famous influencers seem to lead to behavioral bias in the stock market. The stock price changed significantly after those stock influencers shared information or recommended…
Anne Debost‐Legrand, Lemlih Ouchchane, Christine Francannet et al. · 2015 · Birth Defects Research Part A Clinical and Molecular Teratology
BACKGROUND: Transposition of great arteries (TGA) defined as the combination of concordant atrioventricular and discordant ventriculo-arterial connections is one of the most common congenital heart defects. Prenatal diagnosis of TGA…
Márcia Vanacor Barroso, Cristina Vaz Avelar de Carvalho, Rosemar Antoniassi et al. · 2017 · Latin American Journal of Aquatic Research
From early development until the completion of metamorphosis, fat snook (Centropomus parallelus) larvae are commonly fed the rotifers Brachionus spp. and Artemia spp. nauplii. In this study, cultivated copepods Acartia tonsa were evaluated…
Brent A Bushey, Victor H Auld, John E Volk et al. · 2011 · PubMed
This study examined whether combining lipid emulsion and advanced cardiac life support (ACLS) improves survival in an unanesthetized swine model of bupivacaine- and hypoxia-induced cardiovascular collapse. Arterial and venous catheters and…
Arzu Okur, Eylem Pınar Eser, Güldal Yılmaz et al. · 2014 · Journal of Pediatric Hematology/Oncology
Fibrolamellar variant of hepatocellular carcinoma (FLHCC) does not have a favorable prognosis than conventional HCC, and there is no difference regarding the response to chemotherapy and the degree of surgical resectability. FLHCC commonly…
Hee Seung Lee, Sang Hoon Lee, Yun Ho Roh et al. · 2016 · Chemotherapy
BACKGROUND: Surgical resection is the only curative treatment for extrahepatic bile duct cancer. Additionally, the recurrence rate after curative surgery is relatively high, requiring adjuvant therapy. However, the efficacy of adjuvant…
Wändi Bruine de Bruin, Laurel Kruke, Gale M. Sinatra et al. · 2024 · Climatic Change
Abstract The terms “global warming,” “climate crisis,” “climate emergency,” and “climate justice” each draw attention to different aspects of climate change. Psychological theories of attitude formation suggest that people’s attitudes can…
Annie McCluskey, Sally Bennett, Tammy Hoffmann et al. · 2010 · Health Information & Libraries Journal
Abstract Background: Research is essential for evidence‐based practice yet many health professionals do not have enough time to find research. Studies relevant to occupational therapists can be particularly difficult to find. Most search…
Mohammad Reza Beyranvand, Soleyman Farrokhi, Hassan Peyvandi et al. · 2019 · Archives of Industrial Hygiene and Toxicology
Cardiovascular toxicity is the most common cause of fatality in the first 24 hours of poisoning with aluminium phosphide (AlP). Most often manifesting itself in cardiac dysrhythmias. The aim of this study was to evaluate the benefits of amiodarone prophylaxis against cardiac dysrhythmia in 46 patients with acute AlP poisoning. They were divided in two groups of 23: one receiving amiodarone and the other not (control). The treatment group received amiodarone prophylaxis in the initial intravenous bolus dose of 150 mg, followed by a drip of 1 mg/min for six hours and then of 0.5 mg/min for eight
Huanhuan Chang, Jiao Li · 2022 · Journal of Clinical Laboratory Analysis
Abstract Background At present, there is a new variant Omicron BA.2 of SARS‐CoV‐2. In some previous studies, it was found that CBC, NLR, CRP, SAA, etc. in patients with SARS‐CoV‐2 had a series of changes, which were significantly…
Haoran Zhou, Jung-Min Ji, Min Kim et al. · 2018 · Nanomaterials
The rational design of porphyrin sensitizers is always crucial for dye-sensitized solar cells (DSSCs), since the change of only a single atom can have a significant influence on the photovoltaic performance. We incorporated the…
Marlies Oostendorp, Christine H. ten Hove, Miranda van Berkel et al. · 2023 · Archives of Pathology & Laboratory Medicine
Context.— Total serum bilirubin (TSB) analysis is pivotal for diagnosing neonatal hyperbilirubinemia. Because of a routine change in laboratory equipment, our TSB assay changed from a diazo to a vanadate oxidase method. Upon…
Ping Yue, Xiaoan Zuo, Kaihui Li et al. · 2021 · Land Degradation & Development
Abstract As the third most important greenhouse gas, nitrous oxide (N 2 O) poses a significant threat to global warming and the ozone layer. However, the effects of precipitation changes on N 2 O emissions in arid areas remain unclear,…
Gamze Durhan, Ahmet Gürkan Erdemir, Sezin Yuce Sari et al. · 2020 · Breast Care
Objective: Lymphatic irradiation in breast cancer improves locoregional control and has been shown to decrease distant metastasis. However, irradiation also accelerates the formation of atherosclerosis and can cause stenosis,…
Naicheng Wu, Guohao Liu, Min Zhang et al. · 2022 · Animals
One of the key targets of community ecology and biogeography concerns revealing the variability and underlying drivers of biodiversity. Most current studies understand biodiversity based on taxonomic information alone, but few studies have…
B. WIELSTRA, J. W. ARNTZEN · 2014 · Zootaxa
We collected nuclear DNA data (52 markers) with next-generation sequencing for nine Triturus newt specimens, including the holotype and two of the paratypes of T. arntzeni, from the type locality at Vrtovać in eastern Serbia. We compare…
Seo-Ha Jeong, Yeon Gyo Nam · 2024 · Healthcare
Background/Objectives: Globally, life expectancy has been increasing with South Korea focusing on improving health to enhance quality of life. The COVID-19 pandemic further emphasized the need for digital transformation in healthcare,…
Joshua Fisher, Poonam Arora, Sophia Rhee · 2018 · Sustainability
The viability of conservation efforts, including protected areas and buffer zones, depends on finding ways to make those strategies more attractive and viable for local populations. This paper presents a pilot study utilizing a rapid rural…
Barton J. Mann, Taco Gosens, Stephen Lyman · 2012 · The American Journal of Sports Medicine
Treatment outcome researchers in orthopaedics frequently report only tests of statistical significance between group means to evaluate the effectiveness of a given intervention. Although important in establishing that mean differences are…
Joon Young Choi, Jeong Uk Lim, Ho Jung Jeong et al. · 2020 · BMC Pulmonary Medicine
Abstract Background We investigated the association between a combination of two markers, peripheral (PEC) and bronchoalveolar lavage (BAL) eosinophil percentage (BEP), and oxygen requirements in patients with acute eosinophilic pneumonia…
Geoffrey L. Dickens, Laura E. O'Shea · 2017 · International Journal of Forensic Mental Health
Outcomes measures are commonly derived from post-discharge recidivism, readmission, and mortality rates but information about common outcomes across admission is scant. We determined whether reliable and clinically significant change in…
Wenhua Wan, Petra Döll, Hang Zheng · 2022 · Water Resources Research
Abstract To support the implementation of China's carbon neutrality target, this study assesses the impact of future climate change on hydroelectricity production (HP) in China. We developed a hydropower database for mainland China, which…
Fatemeh Mohammadyari, Amirreza Aflak, Mahta ZareDini et al. · 2025 · Frontiers in Medicine
Background: Gastrointestinal bleeding (GIB), which includes both upper GIB (variceal and non-variceal) and lower GIB, represents a significant cause of emergency department referrals. Main body: Given the potential risks of blood transfusion, re-bleeding, and mortality in these patients, it is essential to establish a system for prioritizing critical patients. Several risk stratification scoring systems have been developed based on patients' clinical characteristics and/or endoscopic findings. However, the optimal scoring system for each clinical scenario remains uncertain. Conclusion: In this
Chitra Priyadarshani, Ranjan Laik, Sumit Sow et al. · 2025 · Archives of Agronomy and Soil Science
Integrated crop residue management with micronutrient application can effectively addresses dual challenges of maintaining productivity while enhancing grain nutritional quality of rice in calcareous soils. This study evaluated the role of different soil properties for enhancing yield and grain quality of rice under 29 years of long-term effects of crop residue incorporation and zinc (Zn) fertilization in calcareous Typic Haplaquepts soils. Results showed 100% crop residue incorporation significantly enhanced soil organic carbon (SOC), available nitrogen, available Zn, soil respiration, and we
Muhammad Kamal Uddin, Md Tarikul Islam, Muhammad Asaduzzaman · 2026 · Zenodo (CERN European Organization for Nuclear Research)
A large body of research has documented that smoking behavior is associated with a number of psychological variables. Weiss, Mouttapa, Cen, Johnson, and Unger (2011) studied a culturally diverse sample of 1,771 adolescents who reported that the risk of smoking initiation was significantly higher among students who scored higher on hostility and depressive symptoms, and were bully-victims. Mykletun, Overland, Aaro, Liabo, and Stewart (2008) carried out a population-based health survey on 60,814 adults aged between 20 to 89 years and reported that anxiety and depression were the most common in c