Negative / Null Result ReportOpen accessPsychology
Aljoscha Rimpler, Henk A. L. Kiers, Don van Ravenzwaaij · 2025 · Behavior Research Methods
Interaction effects are very common in the psychological literature. However, interaction effects are typically very small and often fail to replicate. In this study, we conducted a simulation comparing the generalizability and estimability of two linear regression models: one correctly specified to account for interaction effects and one misspecified including simple effects only. We manipulated noise levels, predictor variable correlations, and different sets of regression weights, resulting in 9216 different conditions. From each dataset, we drew 1000 samples of N = 25, 50, 100, 250, 500, a
View details →DOI: 10.3758/s13428-025-02613-6Cited by 26 Negative / Null Result ReportNeuroscience
Julia D. Hur, Loran F. Nordgren · 2016 · Journal of Personality and Social Psychology
The current research examines how exposure to performance incentives affects one's desire for the reward object. We hypothesized that the flexible nature of performance incentives creates an attentional fixation on the reward object (e.g.,…
View details →DOI: 10.1037/pspa0000059Cited by 26 Negative / Null Result ReportOpen accessMedicine
Shaida Andrabi, Justin H. Hwang, Jennifer Kean Choe et al. · 2011 · Journal of Virology
Although members of a virus family produce similar gene products, those products may have quite different functions. Simian virus 40 (SV40) large T antigen (LT), for example, targets p53 directly, but murine polyomavirus LT does not. SV40…
View details →DOI: 10.1128/jvi.05034-11Cited by 26 Negative / Null Result ReportNeuroscience
Mark Alfano · 2018 · PhilPapers (PhilPapers Foundation)
Virtues are dispositions that make their bearers admirable. Dispositions can be studied scientifically by systematically varying whether their alleged bearers are in (or take themselves to be in) the dispositions' eliciting conditions. In…
View details →DOI: 10.4454/teoria.v38i2.49Cited by 26 Negative / Null Result ReportMedicine
Kotaro Matsumoto, Katsuya Suzuki, Keiko Yoshimoto et al. · 2019 · Lara D. Veeken
OBJECTIVES: To elucidate the association between clinical characteristics and immuno-phenotypes in patients with ANCA-associated vasculitis (AAV). METHODS: Peripheral blood from 36 patients with active AAV and 18 healthy controls was…
View details →DOI: 10.1093/rheumatology/kez327Cited by 26 Negative / Null Result Report
Mélusine Boon-Falleur, Adrien Bouguen, Axelle Charpentier et al. · 2022 · Scientific Reports
Abstract Recent empirical research has shown that improving socio-emotional skills such as grit, conscientiousness and self-control leads to higher academic achievement and better life outcomes. However, both theoretical and empirical…
View details →DOI: 10.1038/s41598-021-04046-5Cited by 26 Negative / Null Result Report
Rafael Stern, Jonathan D Muller, Eyal Rotenberg et al. · 2023 · PNAS Nexus
Abstract Suppression of carbon emissions through photovoltaic (PV) energy and carbon sequestration through afforestation provides complementary climate change mitigation (CCM) strategies. However, a quantification of the “break-even time”…
View details →DOI: 10.1093/pnasnexus/pgad352Cited by 26 Negative / Null Result Report
Levon Gabrielian, Luke W. Willshire, Stephen C. Helps et al. · 2011 · Journal of Neurotrauma
Traumatic brain injury (TBI) often causes raised intracranial pressure (ICP), with >50% of all TBI- related deaths being associated with this increase in ICP. To date, there is no effective pharmacological treatment for TBI, partly because…
View details →DOI: 10.1089/neu.2011.1785Cited by 26 Negative / Null Result Report
Jean-Philippe Hauzeur, Chantal Lechanteur, Etienne Baudoux et al. · 2019 · Clinical Orthopaedics & Related Research
Abstract Background In patients with nontraumatic osteonecrosis of the femoral head (ONFH), implantation of bone marrow aspirate concentrate (BMAC) could delay the progression of osteonecrosis and improve symptoms in pre-fracture ONFH.…
View details →DOI: 10.1097/corr.0000000000001107Cited by 26 Negative / Null Result Report
Yangmu Li, J. Terzic, P. G. Baity et al. · 2019 · Science Advances
The superconductivity in a stripe-ordered cuprate appears to change from 3- to 2- to 1-dimensional with increasing magnetic field.
View details →DOI: 10.1126/sciadv.aav7686Cited by 26 Negative / Null Result ReportOpen accessComputer Science
David Graber, Peter Stockinger, Fabian Meyer et al. · 2025 · Nature Machine Intelligence
The field of computational drug design requires accurate scoring functions to predict binding affinities for protein-ligand interactions. However, train-test data leakage between the PDBbind database and the Comparative Assessment of Scoring Function benchmark datasets has severely inflated the performance metrics of currently available deep-learning-based binding affinity prediction models, leading to overestimation of their generalization capabilities. Here we address this issue by proposing PDBbind CleanSplit, a training dataset curated by a new structure-based filtering algorithm that elim
View details →DOI: 10.1038/s42256-025-01124-5Cited by 26 Negative / Null Result ReportOpen accessPhysics and Astronomy
Zhi-zhong Xing, Zhen-hua Zhao, Ye-Ling Zhou · 2015 · The European Physical Journal C
The Majorana nature of massive neutrinos will be crucially probed in the next-generation experiments of the neutrinoless double-beta ( $$0\nu 2\beta $$ ) decay. The effective mass term of this process, $$\langle m\rangle _{ee}$$ , may be contaminated by new physics. So how to interpret a discovery or null result of the $$0\nu 2\beta $$ decay in the foreseeable future is highly nontrivial. In this paper we introduce a novel three-dimensional description of $$|\langle m\rangle _{ee}|$$ , which allows us to see its sensitivity to the lightest neutrino mass and two Majorana phases in a transparent
View details →DOI: 10.1140/epjc/s10052-015-3656-6Cited by 26 Negative / Null Result ReportOpen accessMedicine
John K. Forrest, Steven J. Yakubov, G. Michael Deeb et al. · 2026 · Journal of the American College of Cardiology
BACKGROUND: The Evolut Low Risk trial enrolled patients with severe aortic stenosis at low surgical risk. Annual follow-up is planned for 10 years, evaluating the composite of all-cause mortality or disabling stroke and key secondary…
View details →DOI: 10.1016/j.jacc.2026.02.5063Cited by 26 Negative / Null Result ReportOpen accessMedicine
Carlos Farkas, Andy Mella, Maxime Turgeon et al. · 2021 · Frontiers in Microbiology
An unprecedented amount of SARS-CoV-2 sequencing has been performed, however, novel bioinformatic tools to cope with and process these large datasets is needed. Here, we have devised a bioinformatic pipeline that inputs SARS-CoV-2 genome sequencing in FASTA/FASTQ format and outputs a single Variant Calling Format file that can be processed to obtain variant annotations and perform downstream population genetic testing. As proof of concept, we have analyzed over 229,000 SARS-CoV-2 viral sequences up until November 30, 2020. We have identified over 39,000 variants worldwide with increased polymo
View details →DOI: 10.3389/fmicb.2021.665041Cited by 26 Negative / Null Result Report
Sang Jun Song, Se Gu Kang, Yeon Je Lee et al. · 2018 · Knee Surgery, Sports Traumatology, Arthroscopy
Abstract Purpose In the present study, the early results of sensor‐assisted versus manually balanced posterior‐stabilized total knee arthroplasty (TKA) for osteoarthritis with varus deformities were prospectively compared. Methods Fifty…
View details →DOI: 10.1007/s00167-018-5314-7Cited by 26 Negative / Null Result Report
Joana Paes de Faria, Nicoletta Kessaris, Paul Andrew et al. · 2014 · BMC Neuroscience
Abstract Background Olig1 and Olig2 , encoding closely related basic helix-loop-helix transcription factors, were originally identified in screens for glial-specific genes. Olig1 and Olig2 are both expressed in restricted parts of the…
View details →DOI: 10.1186/1471-2202-15-12Cited by 26 Negative / Null Result ReportOpen accessMedicine
Matthias Diebold, Hannes Vietzen, Andreas Heinzel et al. · 2023 · American Journal of Transplantation
Antibody-mediated rejection (ABMR) is a leading cause of graft failure. Emerging evidence suggests a significant contribution of natural killer (NK) cells to microvascular inflammation (MVI). We investigated the influence of genetically determined NK cell functionality on ABMR development and activity. The study included 86 kidney transplant recipients subjected to systematic biopsies triggered by donor-specific antibody detection. We performed killer immunoglobulin-like receptor typing to predict missing self and genotyped polymorphisms determining NK cell functionality (FCGR3AV/F158 [rs39699
View details →DOI: 10.1016/j.ajt.2023.12.005Cited by 26 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Rodrigo Lasa, Laura Navarro-de-la-Fuente, Anne Gschaedler et al. · 2019 · Insects
Specific ecological interactions between insects and microbes have potential in the development of targeted pest monitoring or control techniques for the spotted wing drosophilid, Drosophila suzukii (Matsumura), an exotic invasive pest of soft fruit. To evaluate D. suzukii attraction to yeast species from preferred types of fruit, three yeasts were isolated from blackberry fruit and two yeasts from raspberry fruit and used to bait simple plastic bottle traps. Saccharomyces cerevisiae and Hanseniaspora uvarum were identified from blackberries, whereas a different H. uvarum strain was identified
View details →DOI: 10.3390/insects10080228Cited by 26 Negative / Null Result ReportOpen accessEnvironmental Science
Anthony Laybros, Daniel Schläpfer, Jean‐Baptiste Féret et al. · 2019 · Remote Sensing
Imaging spectroscopy is a promising tool for airborne tree species recognition in hyper-diverse tropical canopies. However, its widespread application is limited by the signal sensitivity to acquisition parameters, which may require new training data in every new area of application. This study explores how various pre-processing steps may improve species discrimination and species recognition under different operational settings. In the first experiment, a classifier was trained and applied on imaging spectroscopy data acquired on a single date, while in a second experiment, the classifier wa
View details →DOI: 10.3390/rs11070789Cited by 26 Negative / Null Result ReportOpen accessMedicine
Hiroyuki Egami, Tomoya Matsumoto · 2020 · Sustainability
Lack of cash on hand is a significant obstacle in accessing healthcare services in developing countries. Many expectant mothers in the least developed countries do not receive sufficient care during pregnancy due to financial constraints. If such hurdles in accessing healthcare can be overcome, it will contribute to reduction in maternal and newborn mortality, which is a key target of Sustainable Development Goal 3. This study reports the first assessment of the impact of mobile money services on maternal care utilization. We hypothesize that mobile money adoption would motivate rural Ugandan
View details →DOI: 10.3390/su12093741Cited by 26 Negative / Null Result Report
Tom Stafford · 2018 · Psychological Science
Stereotype threat has been offered as a potential explanation of differential performance between men and women in some cognitive domains. Questions remain about the reliability and generality of the phenomenon. Previous studies have found…
View details →DOI: 10.1177/0956797617736887Cited by 26 Negative / Null Result ReportOpen accessPsychology
Robert Young, Daniel Vincent Riordan, Cameron Stark · 2011 · BMC Public Health
BACKGROUND: Past studies using large population based datasets link certain perinatal circumstances (birth weight, parity, etc) with mental health outcomes such as suicide, self-harm and psychiatric problems. Problematically, population datasets omit a number of social confounds. The aim of this study is to replicate past research linking perinatal circumstances and mental health (suicidality and use of psychiatric services) and to determine if such associations remain after adjusting for social circumstances. METHODS: A longitudinal school-based survey of 2157 young people (surveyed at age 11
View details →DOI: 10.1186/1471-2458-11-875Cited by 26 Negative / Null Result ReportSocial Sciences
Martin Merkt, Sabrina Lux, Vincent Hoogerheide et al. · 2019 · Journal of Educational Psychology
Two experiments investigated the effects of an instructional video's setting on learners' retention and application of the video content. Experiment 1 explored competing hypotheses based on theoretical assumptions about whether an…
View details →DOI: 10.1037/edu0000414Cited by 26 Negative / Null Result ReportOpen accessMedicine
Xiaozhun Huang, Lin Xu, Teng Ma et al. · 2021 · Frontiers in Oncology
BACKGROUND: Nivolumab and pembrolizumab disrupt the programmed cell death-1 immune checkpoint and display promising efficacy and safety results in advanced hepatocellular carcinoma (HCC). However, the benefits remain limited. The preliminary results of lenvatinib (LEN) combined with immune checkpoint inhibitors (ICIs) reveal that the combinations were well-tolerated and encouraging. This study aimed to analyze the safety and efficacy of LEN plus ICIs in a real-world cohort of patients with advanced HCC. METHOD: Between June 4, 2017, and June 30, 2019, 16 patients received LEN plus nivolumab, a
View details →DOI: 10.3389/fonc.2021.751159Cited by 26 Negative / Null Result ReportOpen accessImmunology and Microbiology
Madeleine P. J. White, Chris Johnston, John R. Grainger et al. · 2020 · Frontiers in Immunology
Helminth parasites are effective in biasing Th2 immunity and inducing regulatory pathways that minimise excessive inflammation within their hosts, thus allowing chronic infection to occur whilst also suppressing bystander atopic or autoimmune diseases. Multiple sclerosis (MS) is a severe autoimmune disease characterised by inflammatory lesions within the central nervous system; there are very limited therapeutic options for the progressive forms of the disease and none are curative. Here, we used the experimental autoimmune encephalomyelitis (EAE) model to examine if the intestinal helminth He
View details →DOI: 10.3389/fimmu.2020.01830Cited by 26 Negative / Null Result ReportOpen accessEnvironmental Science
Zachary L. Pratt, Bingming Chen, Charles J. Czuprynski et al. · 2012 · Applied and Environmental Microbiology
Salmonella enterica forms aseptate filaments with multiple nucleoids when cultured in hyperosmotic conditions. These osmotic-induced filaments are viable and form single colonies on agar plates even though they contain multiple genomes and…
View details →DOI: 10.1128/aem.01784-12Cited by 26 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Jaehwan Park, Byungkwon Lim · 2018 · International Journal of Financial Studies
This paper explores the market efficiency of the six base metals traded on the LME (London Metal Exchange) using daily data from January 2000 to June 2016. The hypothesis that futures prices 3M (3-month) are unbiased predictors of spot prices (cash) in the LME is rejected based on the false premise that the financialization of commodities has been growing. For the robustness check, monthly data is analyzed using ordinary least squares (OLS) and GARCH (1,1) models. We reject the null hypothesis for all metals except for zinc.
View details →DOI: 10.3390/ijfs6010032Cited by 26 Negative / Null Result ReportOpen accessMedicine
Joshua A. Beckman, Allison B. Goldfine, Alison Goldin et al. · 2010 · The Journal of Clinical Endocrinology & Metabolism
CONTEXT: Antagonism of protein kinase Cbeta (PKCbeta) restores endothelial function in experimental models of diabetes and prevents vascular dysfunction in response to hyperglycemia in healthy humans. OBJECTIVE: We tested the hypothesis…
View details →DOI: 10.1210/jc.2010-0286Cited by 26 Negative / Null Result ReportMedicine
José Marı́a Tolosana, Emilce Trucco, Malek Khatib et al. · 2013 · European Journal of Heart Failure
AIMS: A maximum percentage of ventricular pacing is mandatory to obtain a good response to CRT. Atrioventricular junction (AVJ) ablation has been recommended to attain this objective in patients with AF. THE AIMS OF OUR STUDY WERE: (i) to…
View details →DOI: 10.1093/eurjhf/hft114Cited by 26 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
W-J Xiao, J-W He, H Zhang et al. · 2010 · International Journal of Obesity
OBJECTIVE: Arachidonate 12-lipoxygenase (ALOX12) is a member of the lipoxygenase superfamily, which catalyzes the incorporation of molecular oxygen into polyunsaturated fatty acids. The products of ALOX12 reactions serve as endogenous…
View details →DOI: 10.1038/ijo.2010.157Cited by 26 