Inhibition of Protein Kinase Cβ Does Not Improve Endothelial Function in Type 2 Diabetes
Joshua A. Beckman; Allison B. Goldfine; Alison Goldin; Adnan Pršić; So-Ra Kim; Mark A. Creager · 2010 · The Journal of Clinical Endocrinology & Metabolism
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
CONTEXT: Antagonism of protein kinase Cbeta (PKCbeta) restores endothelial function in experimental models of diabetes and prevents vascular dysfunction in response to hyperglycemia in healthy humans. OBJECTIVE: We tested the hypothesis…
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Metadata source: OpenAlex · DOI 10.1210/jc.2010-0286