Negative / Null Result ReportMedicine
Jin S, Huang J, Wang Y et al. · 2026 · Molecular and cellular biochemistry
Despite observed epidemiological associations, the direct causality between chronic kidney disease (CKD) and senile cataract remains unclear. This bidirectional Mendelian randomization (MR) study assessed the causal associations between…
View details →DOI: 10.1007/s11010-026-05482-5 Negative / Null Result ReportMedicine
Luo J, Huang H, Shao W et al. · 2026 · Journal of affective disorders
Background Whether adolescent major depressive disorder (MDD) with psychotic features has a distinct peripheral metabolite signature remains uncertain. We compared targeted plasma neurotransmitter-related metabolites in psychotic MDD,…
View details →DOI: 10.1016/j.jad.2026.121436 Negative / Null Result Report
Bagdas D, Kebede N, Sedaille J et al. · 2026 · Preprint
Electronic cigarette liquids (e-liquids) often contain flavors and solvents that may influence nicotine addiction. In this study, we characterized the dose-response relationship of commercial unflavored nicotine e-liquids and investigated…
View details →DOI: 10.64898/2026.01.12.697777 Negative / Null Result ReportOpen accessMedicine
Imtiaz S, Russell C, Ali F et al. · 2025 · Substance abuse treatment, prevention, and policy
BACKGROUND: Decriminalization of possession of illegal drugs was implemented in British Columbia, Canada for a three-year period starting from January 31, 2023. As public sentiment played a large role in the outcome of a similar reform in…
View details →DOI: 10.1186/s13011-025-00680-8 Negative / Null Result ReportOpen accessMedicine
Elkhider O, Elshaikh O, Sharma A · 2026 · Cureus
Hemoglobin A1c (HbA1c) reflects average glycemia over approximately two to three months and is widely used for the diagnosis and monitoring of diabetes mellitus; however, discordant results may occur due to analytical interference, altered…
View details →DOI: 10.7759/cureus.108291 Negative / Null Result ReportMedicine
Mulligan DJ, Grasso DJ, Greene CA et al. · 2026 · Research on child and adolescent psychopathology
The latent structure of posttraumatic stress symptoms (PTSS) in early childhood remains poorly understood. This study aimed to assess PTSS in young children, identify underlying latent constructs, and evaluate their construct validity.…
View details →DOI: 10.1007/s10802-025-01396-w Negative / Null Result ReportOpen accessMedicine
Van de Bruaene C, Carbone F, Van den Houte K et al. · 2026 · Journal of neurogastroenterology and motility
Background/aims : The Leuven Postprandial Distress Scale (LPDS) is a validated patient reported outcome (PRO) measure for functional dyspepsia (FD)/postprandial distress syndrome (PDS) patients according to Rome III criteria. However,…
View details →DOI: 10.5056/jnm25108 Negative / Null Result ReportMedicine
Nuutinen V, Kaseva J, Lemola R et al. · 2026 · European Journal of Soil Science.
Deep burrowing earthworms Lumbricus terrestris can be abundant along subdrain trenches, creating macropores that may serve as preferential flow paths for particles and agrochemicals to subdrains. We examined L. terrestris abundance,…
Negative / Null Result ReportMedicine
Khani E, Khoshbaten M, Jafarabadi MA et al. · 2026 · Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology
Background and study aims Despite being the leading cause of liver-related mortality, the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) remains challenging. This study aimed to assess the effects of…
View details →DOI: 10.1016/j.ajg.2025.11.004 Negative / Null Result ReportMedicine
McLeod A, Rullmann M, Hinderberger P et al. · 2026 · Neuroscience
A single nucleotide polymorphism in the brain derived neurotrophic factor (BDNF)-encoding gene leads to diminished BDNF signaling resulting from Val66Met and has been linked to obesity. Previous imaging studies regarding the impact of BDNF…
View details →DOI: 10.1016/j.neuroscience.2026.03.008 Negative / Null Result Report
Humayun SE, Bailey CD · 2025 · Preprint
The human brain exhibits distinct patterns of electrical activation in response to various stimuli—from sensory information to our most subtle feelings. These patterns have been used to demonstrate hemispheric differences in information…
View details →DOI: 10.31234/osf.io/rg6kx_v1 Negative / Null Result ReportMedicine
Kastrati G, Sopaj F, Bytyqi V et al. · 2025 · Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
The study involved the determination of the concentrations of 11 potentially toxic elements (PTEs) in soil, honey, and pollen samples collected in the territory of Kosovo, followed by a statistical analysis. Inductively coupled…
View details →DOI: 10.1080/10934529.2025.2594372 Negative / Null Result Report
Niedtfeld I, Störkel L, Didushok V et al. · 2025 · Preprint
The first impression a person makes can substantially influence whether and how they areapproached and treated by others. Prior research on this process suggests that individualsexhibiting higher levels of maladaptive personality traits…
View details →DOI: 10.31234/osf.io/k9sdg_v1 Failed Experiment ReportOpen accessMedicine
· 2025 · International wound journal
Retraction C.-S. Li, X.-F. Li, X.-Y. Huang, and F.-F. Chen, "Evaluating the Effectiveness of Echocardiographic Guidance in Diminishing Postoperative Wound Complications for Left Atrial Appendage Closure: A Clinical Retrospective Study,"…
View details →DOI: 10.1111/iwj.70619 Negative / Null Result ReportMedicine
Alexander KN, Turner MS, Salazar JP et al. · 2025 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
Many adolescents experience peer victimization during this critical period for development. Emotion regulation strategies, including cognitive reappraisal and emotional suppression, can help adolescents cope with such experiences. Although…
View details →DOI: 10.1111/jora.70119 Negative / Null Result Report
DeStefano L, Kim H, Erickson C et al. · 2025 · Preprint
Abstract Background: Fragile X syndrome (FXS) is characterized by sensory hypersensitivity and neural hyperexcitability linked to GABAergic dysfunction. BAER-101, formerly known as AZD7325, is a positive allosteric modulator of GABA A…
View details →DOI: 10.21203/rs.3.rs-8123031/v1 Negative / Null Result Report
Hogins J, Mekala S, Resendiz J et al. · 2025 · Preprint
At least half of all women will experience a urinary tract infection (UTI) in their lifetime. Age, sexual activity, hormonal status, and the urinary tract microbiome (urobiome) contribute to the probability of infection. While studies have…
View details →DOI: 10.1101/2025.11.04.686513 Negative / Null Result Report
Pollet TV, Fitzpatrick B, Meziani S et al. · 2025 · Preprint
Birth order has long been argued to be an important individual difference variable for domains such as personality and achievement. However, after many decades of research, the evidence for a birth order effect is scarce at best. Less is…
View details →DOI: 10.31234/osf.io/hn2j4_v1 Negative / Null Result ReportMedicine
Ishiguro S, Guitard D, Saint-Aubin J · 2025 · Quarterly journal of experimental psychology (2006)
Semantic relatedness of items improves working memory performance. We targeted one type of semantic relatedness, semantic association. The beneficial effect of association is often explained by the spreading-activation process:…
View details →DOI: 10.1177/17470218251392562 Negative / Null Result Report
Kemp EC, Dontha M, Du Z et al. · 2025 · Preprint
Background. Callous-unemotional (CU) traits (i.e., “Limited Prosocial Emotions”) characterize a particularly severe group of antisocial youth. “Secondary” CU traits, as opposed to “primary,” are distinguished by co-occurring anxiety and…
View details →DOI: 10.31234/osf.io/s7y5t_v1 Negative / Null Result ReportOpen accessMedicine
Güneş M · 2025 · Medicine
Magnesium has numerous important functions in human metabolism. Low magnesium level is a common finding in type 2 diabetes mellitus (T2DM) but the causes have not been sufficiently investigated. Smoking is associated with major health…
View details →DOI: 10.1097/md.0000000000046172 Negative / Null Result ReportMedicine
Grant S, Goldberg E, Gadipudi A et al. · 2025 · Journal of racial and ethnic health disparities
Black transgender women report high levels of discrimination, which is associated with poor health outcomes. Some evidence suggests that intersectional discrimination-that is, interacting forms of marginalization related to one's real or…
View details →DOI: 10.1007/s40615-025-02710-4 Negative / Null Result ReportMedicine
Bagby RM, Mortezaei A, McIntyre C et al. · 2026 · Journal of personality assessment
The Perth Alexithymia Questionnaire (PAQ) was developed to assess alexithymia as a multidimensional construct consistent with the attention-appraisal model. This study evaluated the hierarchical structure of the PAQ using Goldberg's…
View details →DOI: 10.1080/00223891.2025.2559701 Negative / Null Result ReportMedicine
Ferreira-Correia A, Mnisi N, Harwood K et al. · 2025 · Applied neuropsychology. Adult
The Working Memory Questionnaire (WMQ) was developed to assess everyday difficulties associated with working memory (WM) impairments. This study evaluated the psychometric properties of the WMQ within a South African context. A…
View details →DOI: 10.1080/23279095.2025.2556922 Negative / Null Result ReportOpen accessMedicine
Baysari M, Stanceski K, Bamgboje-Ayodele A et al. · 2026 · BMC medical informatics and decision making
Background Single sign-on (SSO), tap-on-tap-off (TOTO) and virtual desktops (VD) are increasingly being used in hospitals to reduce the burden and risks of password management, but we know little about how these systems are used in…
View details →DOI: 10.1186/s12911-026-03424-1 Negative / Null Result ReportOpen accessMedicine
Awada Z, Kazmi N, Jones HJ et al. · 2026 · BMC cancer
BACKGROUND: Breast cancer (BC) is the leading cause of cancer incidence worldwide. Observational studies have suggested that hypertension may be a risk factor for BC. We tested whether systolic blood pressure (SBP) may influence BC and BC…
View details →DOI: 10.1186/s12885-025-15513-x Negative / Null Result ReportMedicine
Shah H, Ali M, Kilgallon JL et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Neurosurgery and neurosurgical care continues to evolve and to embrace technological advances. AI is used to interpret radiological studies and to distill medical information, with the potential to help guide physicians and patients in…
View details →DOI: 10.1016/j.jocn.2025.111731 Negative / Null Result ReportMedicine
Nishida S, Watanabe N, Hashimoto K et al. · 2026 · Journal of plant research
Reproductive interference is a negative interspecific interaction that can drive mutually exclusive distributions of closely related species. While recent research indicates that reproductive interference in plants frequently occurs during…
View details →DOI: 10.1007/s10265-025-01681-1 Replication FailureMedicine
Nissi L, Elseragy A, Wahab A et al. · 2026 · American journal of otolaryngology
Background Depth of invasion (DOI) is a well-established prognostic factor in oral cavity squamous cell carcinoma (OSCC). Incorporating DOI into the OSCC staging system has substantially refined T-classification and now informs key…
View details →DOI: 10.1016/j.amjoto.2026.104869 Failed Experiment ReportMedicine
Looman MI, Klau MM, Schoenmakers TM et al. · 2026 · Journal of sleep research
While time in bed restriction is a core treatment mechanism of Sleep Restriction Therapy (SRT), empirical research has not yielded a relationship between insomnia improvement and adherence to the prescribed time in bed. We coin this…
View details →DOI: 10.1111/jsr.70339 