e-ISSN: Pending
Replication FailureMedicine

Prognostic role of histological depth of invasion in T1-2 oropharyngeal squamous cell carcinoma.

Nissi L; Elseragy A; Wahab A; Wennerstrand P; Knuutila M; Routila J; Huusko T; Irjala H · 2026 · American journal of otolaryngology

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Background Depth of invasion (DOI) is a well-established prognostic factor in oral cavity squamous cell carcinoma (OSCC). Incorporating DOI into the OSCC staging system has substantially refined T-classification and now informs key…

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Metadata source: Europe PMC · DOI 10.1016/j.amjoto.2026.104869