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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21379 results · page 683 of 713

Negative / Null Result ReportMedicine

How are host-parasite interactions affected by veterinary anti-parasitic treatment? An experimental approach.

Lorrain-Soligon L, Agostini S, Biard C et al. · 2025 · Environmental toxicology and pharmacology

The effects of veterinary anti-parasitic compounds on wild fish species and their parasites are poorly investigated. Bithionol, an antibacterial, anthelmintic, and algaecide, is commonly used in aquaculture to control parasitic infections,…

View details →DOI: 10.1016/j.etap.2025.104782
Negative / Null Result ReportMedicine

Audit and feedback: effects on professional practice.

Ivers N, Yogasingam S, Lacroix M et al. · 2026 · The Cochrane database of systematic reviews

Background Audit and feedback (A&F) is a widely used strategy to improve professional practice. This is supported by prior Cochrane reviews and behavioural theories describing how healthcare professionals are prompted to modify their…

View details →DOI: 10.1002/14651858.cd000259.pub5
Negative / Null Result ReportOpen accessMedicine

Is Religious Coping a Protective Factor, and for Whom? A Moderation and Subgroup Analysis on Loneliness and Suicide Attempts Among LGBTQ+ Adults Raised as Latter-Day Saints.

Kim S, Lefevor GT, Miller CK et al. · 2026 · Suicide & life-threatening behavior

Introduction LGBTQ+ adults face elevated rates of loneliness and suicide attempts, yet little research has examined whether religious coping-a protective factor for people generally-effectively mitigates these risks for LGBTQ+ adults…

View details →DOI: 10.1111/sltb.70088
Negative / Null Result ReportMedicine

MALICoT: A pilot cross-sectional study analyzing the effects of power training and age on endomysium content and fiber area in the soleus muscle of adult males.

Clemen, Humbsch, Berwanger et al. · 2026 · Physiological reports

The cross-sectional Master Athletic Laboratory Study of Intramuscular Connective Tissue (MALICoT, DRKS00015764) examined effects of athletic exercise and age on endomysium content in human soleus muscle. Forty-three clinically healthy male…

View details →DOI: 10.14814/phy2.70933
Negative / Null Result ReportMedicine

Serum free fatty acids and progression of coronary artery calcification: sex specific findings from a large U.S. cohort study.

Ramezankhani, Hadaegh, Esmaeili · 2026 · BMC cardiovascular disorders

Studies evaluating the longitudinal relationship between plasma free fatty acids (FFAs) and subclinical atherosclerosis remain limited. We investigated the prospective association between serum FFA levels and the progression of coronary…

View details →DOI: 10.1186/s12872-026-05692-1
Negative / Null Result ReportMedicine

Renin, Aldosterone, and Treatment Response to Dapagliflozin, Spironolactone, and Their Combination: An Analysis From SOGALDI-PEF.

Ferreira, Marques, Neves et al. · 2026 · JACC. Heart failure

Hypertension and heart failure with preserved ejection fraction (HFpEF) often coexist, and sodium retention is a common feature of both conditions. Renin levels are suppressed in the setting of sodium overload and may modulate the blood…

View details →DOI: 10.1016/j.jchf.2026.103111
Negative / Null Result ReportMedicine

Antifungal Potential of Bacillus spp., Streptomyces spp. and Trichoderma asperellum Against Phytopathogenic Fungi.

Seņkovs, Nikolajeva, Rubene et al. · 2026 · Pathogens (Basel, Switzerland)

The increasing demand for sustainable plant protection products has intensified interest in microbial biocontrol agents (BCAs). This study aimed to evaluate the antifungal activity of selected Streptomyces , Bacillus , and Trichoderma…

View details →DOI: 10.3390/pathogens15050458
Negative / Null Result ReportMedicine

The Effect of Griffonia simplicifolia on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers-A Randomized, Double-Blinded, Placebo-Controlled Crossover Trial.

Schlemmer, Hammer, Fandler-Höfler et al. · 2026 · Nutrients

Background : The plant Griffonia simplicifolia is marketed as a dietary supplement; it is said to have antidepressant and sleep-promoting properties. Its main ingredient, 5-hydroxytryptophan (5-HTP), is the immediate precursor of serotonin…

View details →DOI: 10.3390/nu18101609
Negative / Null Result ReportMedicine

Clinical Strategies to Improve the Accuracy of Articulating Paper for Detecting Occlusal Contact Points in Adults with Natural Dentitions.

Rovira-Lastra, ElOtmani-Sabiri, Ustrell-Barral et al. · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives : This clinical study assessed the validity of articulating paper for detecting occlusal contacts points, including examining the effects of clinical technique, paper thickness, and the arch. Methods : This…

View details →DOI: 10.3390/diagnostics16101450
Negative / Null Result ReportMedicine

Upper Arm to Upper Leg Length Ratio and Dyslipidemia: A Novel Application of a Fixed Skeletal Proportion Metric in a Nationally Representative U.S. Sample.

Ahmed, Nath, Jahan et al. · 2026 · International journal of environmental research and public health

Conventional anthropometric measures used to predict dyslipidemia, such as body mass index and waist circumference, vary over time and may not fully capture early-life influences on metabolic risk. Fixed skeletal proportions, including…

View details →DOI: 10.3390/ijerph23050662
Negative / Null Result ReportMedicine

Low-Volume Versus Standard-Volume Pericapsular Nerve Group Block with and Without Dexamethasone for Postoperative Analgesia After Total Hip Arthroplasty: A Randomized Controlled Trial.

Reysner, Ciftci, Alver et al. · 2026 · Journal of clinical medicine

Background: The pericapsular nerve group block provides motor-sparing analgesia after total hip arthroplasty, but the optimal injectate volume and the role of dexamethasone remain unclear. Methods: In this prospective, randomized,…

View details →DOI: 10.3390/jcm15103676
Negative / Null Result ReportMedicine

Hope for Romantic Relationships: Validation of a Brief Scale.

Marici, Marina, Cormoș · 2026 · Behavioral sciences (Basel, Switzerland)

This study aimed to develop and validate a brief measure of hope for romantic relationships (HRR), conceptualized as a future-oriented evaluation of relational continuity and quality. The sample consisted of 525 participants. Exploratory…

View details →DOI: 10.3390/bs16050775
Negative / Null Result ReportMedicine

The Effect of Acupressure on Procedural Pain, Anxiety, and Hemodynamic Parameters During Chest Tube Removal in Open-Heart Surgery Patients: A Randomized Sham-Controlled Study.

Kandemir, Yüksel, Çam Yanık et al. · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses

Patients undergoing open-heart surgery often experience procedural pain and anxiety during chest tube removal (CTR), which can lead to serious complications, along with potential changes in hemodynamic parameters such as blood pressure,…

View details →DOI: 10.1016/j.pmn.2026.04.010
Negative / Null Result ReportMedicine

Effects of Tele-Pilates Exercise on Menopausal and Urogenital Symptoms and Psychosocial Outcomes in Postmenopausal Women: A Randomized Controlled Trial.

Arslan, Tufekci, Acar et al. · 2026 · International urogynecology journal

This study aimed to examine the effects of tele-Pilates exercise on menopausal symptoms, quality of life, depression, and anxiety levels in postmenopausal women. Forty postmenopausal women were separated into two groups: as tele-Pilates…

View details →DOI: 10.1007/s00192-026-06713-5
Negative / Null Result ReportMedicine

Characterizing the nasal microbiome using a nasal allergen challenge model.

Linton, Sjaarda, Hossenbaccus et al. · 2026 · The Journal of allergy and clinical immunology

The role of the nasal microbiome in allergic rhinitis (AR), particularly following direct allergen exposure using a controlled model, is incompletely understood. Understanding microbiome dynamics after allergen challenge could provide…

View details →DOI: 10.1016/j.jaci.2026.05.003
Negative / Null Result ReportMedicine

Assessment of the effects of ethnicity, home language, and socioeconomic status on neurodevelopmental performance in a multiethnic population.

Haughey, Samara, Al-Rifai et al. · 2026 · BMJ paediatrics open

To investigate a unique, multicultural population to allow us to examine the association of ethnicity, socioeconomic status (SES) and spoken language at home on performance using developmental assessment tools. Analysis of a prospective…

View details →DOI: 10.1136/bmjpo-2025-004118
Negative / Null Result ReportMedicine

Three-Season Analysis of Physical Performance in Professional English Football: Influence of Match Outcome, Match Location, and Players' Position During Official Competitions.

Beato, Allen, Jamil et al. · 2026 · Journal of strength and conditioning research

Beato, M, Allen, M, Jamil, M, and Vicens Bordas, J. Three-season analysis of physical performance in professional English football: Influence of match outcome, match location, and players' position during official competitions. J Strength…

View details →DOI: 10.1519/jsc.0000000000005410
Negative / Null Result ReportMedicine

Effects of Dietary Nitrate and Caffeine on End Power and Work Above End Power During a 3 min All-Out Test in Trained Male Cyclists.

Hagele, Sunderland, Mumford et al. · 2026 · Nutrients

The purpose of this study was to examine the effects of acute dietary nitrate (NO 3 - ) and caffeine (CAF) supplementation on end power (EP) and work performed above EP (WEP) in trained male cyclists during a 3 min all-out test (3MT) on a…

View details →DOI: 10.3390/nu18091463
Negative / Null Result ReportMedicine

Systemic Inflammatory and Hematologic Biomarkers in Pediatric Dental Caries: Clear Group Differences with Limited Independent Association with DMFT.

Petrache, Boldeanu, Diaconu et al. · 2026 · Journal of clinical medicine

Background: Dental caries in children has been explored not only as a local oral condition but also in relation to potential systemic inflammatory changes. This study evaluated systemic inflammatory biomarkers and hematologic indices in…

View details →DOI: 10.3390/jcm15093558
Negative / Null Result ReportMedicine

Clinical features of biliary atresia complicated by cytomegalovirus infection and prognostic analysis after Kasai portoenterostomy.

Teng, Wenqing, Shuhao et al. · 2026 · Journal of pediatric surgery

To explore the unique clinical characteristics of biliary atresia (BA) combined with cytomegalovirus (CMV) infection and its impact on early and late prognosis after Kasai portoenterostomy (KPE). This was a retrospective study involving…

View details →DOI: 10.1016/j.jpedsurg.2026.163190