Negative / Null Result Report
Chang DS, Littlepage-Saunders M, Hochstein MJ et al. · 2023 · Preprint
Convergent lines of evidence from animal models suggest that disrupted metabotropic glutamate receptor 2 (mGlu 2 ) function promotes high levels of drug consumption for a variety of psychoactive drugs including alcohol, opioids, and…
View details →DOI: 10.1101/2023.09.15.558004 Negative / Null Result ReportMedicine
Erickson MG, Reinhardt LA, Svaren L et al. · 2024 · Journal of dairy science
Reducing dietary CP is a well-established means to improve N use efficiency. Yet, few studies have considered if transient restrictions in dietary CP could reduce the environmental footprint of late-lactation cows. We hypothesized that the…
View details →DOI: 10.3168/jds.2023-24150 Negative / Null Result ReportOpen accessMedicine
Colomer-Poveda D, Mera-González I, Marcos-Frutos D et al. · 2026 · European journal of applied physiology
PURPOSE: The aim of this triple-blind, placebo-controlled study was to determine the effects of anodal transcranial direct current stimulation (a-tDCS) applied over the primary motor cortex (M1) and the dorsolateral prefrontal cortex…
View details →DOI: 10.1007/s00421-026-06186-w Negative / Null Result Report
Turan G, Spiertz V, Bein O et al. · 2023 · Preprint
The human brain is postulated to function as a prediction machine, constantly comparing incoming sensory input to predictions based on past experiences. When an event contradicts these predictions, it results in a prediction error (PE),…
View details →DOI: 10.22541/au.168663255.58375954/v1 Negative / Null Result ReportOpen accessMedicine
Agir M, Sahin K, Pulatkan A et al. · 2026 · JSES international
Background Rotator cuff tears are a leading cause of shoulder pain, with high rerupture rates despite advancements in surgical techniques. Tendon-to-bone healing failure is often attributed to insufficient fibrocartilage regeneration at…
View details →DOI: 10.1016/j.jseint.2025.101425 Negative / Null Result ReportOpen accessMedicine
Meier K, van Hoeken D, Kager CCM et al. · 2025 · The International journal of eating disorders
Objective This study examined the impact of the COVID-19 pandemic on incidence rates of anorexia nervosa (AN) and bulimia nervosa (BN) in Dutch primary care by comparing pre-pandemic (2015-2019) and in-pandemic (2020-2022) periods. We…
View details →DOI: 10.1002/eat.24431 Negative / Null Result ReportOpen accessMedicine
Haucke M, Heinz A, Heinzel S et al. · 2025 · European archives of psychiatry and clinical neuroscience
Adverse alcohol consumption is a major public health concern, which might have been further increased by the COVID-19 pandemic. In this study we investigated the impact of a lockdown stage on the association between alcohol consumption,…
View details →DOI: 10.1007/s00406-024-01941-6 Negative / Null Result ReportMedicine
Hascher K, Brown R, Janulis P et al. · 2026 · Biopsychosocial science and medicine
Objective Sexual minority (SM) populations experience worse cardiovascular health than heterosexual populations. One potential pathway is the effects of disclosure (sharing) or concealment (withholding) of SM identity due to anticipated…
View details →DOI: 10.1097/psy.0000000000001422 Negative / Null Result ReportOpen accessMedicine
Kweon J, Ganesh P, Brown JC · 2025 · Transcranial magnetic stimulation (2024)
Health and behavioral factors likely influence repetitive transcranial magnetic stimulation (rTMS) effectiveness, though clear support is lacking. Since habitual caffeine use has been found to impair corticomotor plasticity, we…
View details →DOI: 10.1016/j.transm.2025.100199 Negative / Null Result ReportMedicine
Chung YH, Williams LH, Brady TF et al. · 2025 · Journal of experimental psychology. General
Across many studies, verbal labels have been shown to significantly affect perceptual and cognitive processes. Here, we ask whether verbal labels can also improve visual working memory performance by making objects more recognizable. In a…
View details →DOI: 10.1037/xge0001801 Negative / Null Result ReportMedicine
Popovic D, Reddy YNV, Omar M et al. · 2025 · Mayo Clinic proceedings
Objective Myeloperoxidase (MPO) is a heme peroxidase that scavenges nitric oxide and contributes to microvascular dysfunction. Patients with heart failure and preserved ejection fraction (HFpEF) have microvascular dysfunction that leads to…
View details →DOI: 10.1016/j.mayocp.2025.02.022 Negative / Null Result ReportOpen accessMedicine
Cohen M, Orgel E, Nevarez-Mejia J et al. · 2025 · EJHaem
Introduction Obesity contributes to poorer clinical outcomes in patients with acute lymphoblastic leukemia. We have shown that adipocytes cause anthracycline resistance by absorbing and metabolizing them into less-active alcohol…
View details →DOI: 10.1002/jha2.70140 Negative / Null Result ReportMedicine
Więcławski W, Smus A, Binder M · 2025 · Vision research
Pupillary light response (PLR) is modulated by the allocation of spatial attention. Larger pupil constrictions for bright stimuli presented on the left side are considered indicative of pseudoneglect, a subtle attentional bias observed in…
View details →DOI: 10.1016/j.visres.2025.108618 Negative / Null Result ReportOpen accessMedicine
Mielniczek M, Lunde P, Grzyb W et al. · 2025 · Journal of functional morphology and kinesiology
Objective: The aim of the study was to investigate the effect of eight weeks of in-season training with wearable resistance attached to the forearm on spike velocity in female volleyball players. Methods: A total of 13 senior female…
View details →DOI: 10.3390/jfmk10040458 Negative / Null Result ReportMedicine
Müller A, Zethof JHT, Pirani C et al. · 2025 · Rhizosphere
Biofilm formation on plant roots is traditionally assumed an important trait for plant growth promoting rhizobacteria, but its importance in the interplay between soil, plant roots and the rhizosphere bacterial and archaeal community is…
Negative / Null Result ReportMedicine
Sasaki AE, Benites NM, Rodrigues B et al. · 2025 · Hearing research
Rodent auditory brainstem neurons undergo substantial electrophysiological maturation during the postnatal period, spanning both pre- and post-hearing phases. These developmental adaptations support high-frequency, temporally precise…
View details →DOI: 10.1016/j.heares.2025.109388 Negative / Null Result ReportOpen accessMedicine
Duong LHK, Lam NV, Tran VT · 2025 · Life (Basel, Switzerland)
Background: Atrial high-rate episodes (AHREs) detected by pacemakers are linked to increased stroke risk. The predictive value of high-sensitivity cardiac troponin I (hs-cTnI) for AHREs in pacemaker patients remains uncertain. This study…
View details →DOI: 10.3390/life15121850 Negative / Null Result ReportOpen accessMedicine
Kim SH, Heo JH, Cunanan K et al. · 2026 · Journal of the Endocrine Society
Context While popular weight-loss medications have raised concerns about lean mass loss, the normative effects of nonpharmacologic weight loss on body composition remain unclear. Objective We assessed how the extent of weight loss from…
View details →DOI: 10.1210/jendso/bvag015 Failed Experiment Report
Seetahul Y, Greitemeyer T · 2025 · Preprint
Objective: With two experiments (N = 1,576), we examine the causal effect of frustration on the immediate inclination to play violent video games (VVGs) and the moderating role of long-term VVG exposure. Method: Frustration was…
View details →DOI: 10.31234/osf.io/pwkny_v2 Failed Experiment ReportMedicine
Ogawa M, Matsumoto K, Aoyama K et al. · 2025 · IEEE transactions on visualization and computer graphics
Virtual reality (VR) enables beyond-real interactions (BRI) that transcend physical constraints, offering effective user experiences like extending a hand to grasp distant objects. However, adapting to novel mappings of BRI often reduces…
View details →DOI: 10.1109/tvcg.2025.3549562 Failed Experiment ReportOpen accessMedicine
Cong YQ, Yurdum L, Fischer A et al. · 2025 · Journal of nonverbal behavior
The ingroup advantage refers to the phenomenon of emotions being more accurately recognised when expressors and perceivers share the same cultural background. Though well-documented in studies using posed facial expressions, whether the…
View details →DOI: 10.1007/s10919-025-00492-1 Failed Experiment ReportMedicine
Sabino-Carvalho JL, Guerrero RV, Teixeira AL et al. · 2025 · Autonomic neuroscience : basic & clinical
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by non-motor symptoms and marked altered sympathetic and parasympathetic activity. However, it is currently unclear if inappropriate autonomic adjustments are…
View details →DOI: 10.1016/j.autneu.2025.103311 Negative / Null Result ReportMedicine
Parsowith EJ, Herring E, Cohen B et al. · 2025 · Experimental gerontology
Background Over 25% of U.S. older adults experience chronic knee pain, which worsens with inactivity, creating a cycle of pain, disability, and sedentary behavior. However, a limited understanding of the underlying mechanisms hinders the…
View details →DOI: 10.1016/j.exger.2025.112803 Negative / Null Result ReportMedicine
Rubino M, Fan R', Kulesz PA et al. · 2026 · The Laryngoscope
Objectives Complete or relative voice rest is recommended following phonomicrosurgery. Primarily, adherence to rest has been measured using patient reports, but their validity is unknown. Instrumental measures of rest adherence are…
View details →DOI: 10.1002/lary.70432 Negative / Null Result ReportOpen accessMedicine
Bertram AM, Lalot F, van der Werff L et al. · 2025 · Frontiers in psychology
Introduction Many daily situations require rapid judgments about whether information is true or false based on limited information. Prior research has predominantly examined how statement and source characteristics influence these…
View details →DOI: 10.3389/fpsyg.2025.1626047 Negative / Null Result ReportMedicine
Alharbi BM, Williams HE, Parr T et al. · 2025 · Mathematical biosciences
We propose a mathematical model based on coupled ordinary differential equations (ODEs) for metabolite concentrations with the aim of investigating how modifications to the rates affects outputs from a regulatory network. Our aim is to…
View details →DOI: 10.1016/j.mbs.2025.109455 Negative / Null Result ReportMedicine
Poller A, Jha S, Molander L et al. · 2025 · International journal of cardiology
Background It is incompletely understood why patients with takotsubo syndrome (TS) have milder symptoms and a better hemodynamic profile than patients with ST-elevation myocardial infarction (STEMI) despite similar or more extensive…
View details →DOI: 10.1016/j.ijcard.2025.133668 Negative / Null Result Report
López-Moraga A, De Ceuninck M, Van der Heyden Y et al. · 2025 · Preprint
Although avoidance can serve an adaptive function in daily life, excessive or persistent avoidance can form a debilitating symptom of anxiety-related disorders. The transition from adaptive to maladaptive avoidance remains poorly…
View details →DOI: 10.1101/2025.02.28.640742 Negative / Null Result ReportOpen accessMedicine
Maier LE, Vanden Berg ER, Simpson L et al. · 2026 · Physiological reports
This study examined how sex influences blood flow during exercise at altitude and relative contributions of adrenergic mechanisms. Thirteen participants (8 M/5F) were tested at low and high altitude (days 3-11). Participants performed…
View details →DOI: 10.14814/phy2.70754 Negative / Null Result ReportOpen accessMedicine
Rikken RM, Yaqub M, Coomans EM et al. · 2025 · Alzheimer's research & therapy
Background Neuroinflammation plays a key role in Alzheimer's disease (AD) pathophysiology, but it is not clear how neuroinflammation contributes to disease progression. We aim to investigate the role of neuroinflammation on longitudinal…
View details →DOI: 10.1186/s13195-025-01915-3 