A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21742 results · page 659 of 725
Tuddenham S, Brotman RM, Handa VL · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Approximately 60% of adult women experience at least 1 urinary tract infection, and more than 25% experience multiple recurrences. If persistent bacterial reservoirs in the urinary tract contribute to the high incidence of…
Pengpid S, Peltzer K, Hajek A · 2026 · Australasian journal on ageing
Objectives The aim of this study was to assess the longitudinal association between transitioning to adult caregiving, grandparent childcare and mental health outcomes (depressive symptoms, life satisfaction and cognitive functioning) and…
Theophil M, Lyimo AA, Ambikile JS · 2026 · PloS one
Background Chronic Kidney Disease (CKD) is a significant global health challenge, particularly among people living with HIV (PLHIV) on antiretroviral therapy (ART). The combined effects of HIV infection, long-term ART exposure, and other…
Aarhus M, Netteland DF, Tverdal C et al. · 2026 · Acta neurochirurgica
Purpose Traumatic brain injury (TBI) in patients ≥ 80 years poses major clinical challenges, with limited evidence to guide neurosurgical decision-making. We evaluated mortality, functional outcomes, and prognostic factors in patients…
Fisayo T, Evans C, Mutasa K et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Cytomegalovirus (CMV) co-infection is associated with mortality in adults with HIV, but whether CMV is associated with mortality in children with HIV remains uncertain. Methods In 498 children (median age 6.3 years,…
Mayo AK, Beaudoin JJ, Woodhead JL et al. · 2026 · Clinical pharmacology and therapeutics
Obeticholic acid (OCA), a synthetic analog of chenodeoxycholic acid, was approved in 2016 for the treatment of primary biliary cholangitis. Early clinical trials revealed elevated liver biomarkers in healthy subjects receiving…
Frey L, Grunwald S, Ruckes C et al. · 2026 · European urology open science
Background and objective Metastatic testicular germ cell tumors (mTGCTs) are treated with combination chemotherapy (Cx) containing bleomycin (BEP [bleomycin, etoposide, and cisplatin]). Bleomycin-induced pulmonary toxicity (BPT) is a…
Liang D, Tong Y, Li F et al. · 2026 · Cerebrovascular diseases (Basel, Switzerland)
Introduction General anesthesia (GA) with endotracheal intubation is standard during endovascular treatment (EVT) for acute ischemic stroke (AIS), but the optimal timing for post-procedural extubation remains unclear. Methods In this…
Radha S, Arends M, Kislinger G et al. · 2026 · PLoS biology
Rapid information processing in complex organisms depends on myelin, which consists of a multilamellar membrane that tightly adheres to the axonal surface along the internode and at paranodal loops, where specialized adhesion proteins…
Mirda D, Hao J, Dungan M et al. · 2026 · Cancers
Background : Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC), and colorectal surveillance has been shown to reduce death from CRC in this high-risk population. This study aimed to examine adherence to…
Ito K, Fujii M, Oba Y et al. · 2026 · International orthopaedics
Purpose To determine changes in low back pain (LBP) after total hip arthroplasty (THA), identify preoperative factors associated with residual LBP and LBP improvement, and clarify the association between residual LBP and patient-reported…
Hamasaki H, Taxiarchi V · 2026 · Preprint
Aims Sarcopenia and sarcopenic obesity are associated with increased risks of cardiovascular (CV) disease and mortality. This study examined the associations of body composition and daily physical activity with mortality, CV events and…
Cunningham PM, Hayes JE · 2026 · Appetite
Widespread nutrition advice instructs consumers to drink water with meals to increase fullness and reduce energy intake. However, recent data indicates greater water intake is associated with more food intake at a meal, not less. Switching…
Charoenrat B, Sungkarat S, Phirawatthakul C et al. · 2026 · BMC geriatrics
Background Neck pain is associated with altered postural and gait performance in older adults. Smartphone use may further challenge postural and gait control due to additional cognitive and motor demands. This study aimed to investigate…
Ediz E, Küçükdağ HN, Özel MA · 2026 · Scientific reports
Although high fructose consumption is known to be associated with metabolic disorders, specific intake thresholds and consumption patterns related to hepatic steatosis have not been fully defined. This study aimed to quantify daily…
Millarch AS, Schøning J, Hjulmand VG et al. · 2026 · The journal of trauma and acute care surgery
Background Opioids have a well-known capacity to induce long-term dependency with related increased morbidity and mortality. Usage patterns following traumatic injury are, however, not well studied. We investigated long-term opioid usage…
Shishimi G, Akaishi R, Matsukami M · 2025 · Preprint
Mirror self-recognition (MSR) is a key indicator of self-awareness, primarily studied in vertebrates. Investigating MSR in invertebrates such as the western honeybee ( Apis mellifera ), an insect with advanced cognition, is essential to…
Kato K, Honda Y, Kamatani T et al. · 2026 · Arthritis & rheumatology (Hoboken, N.J.)
Objective Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory disease caused by gain-of-function mutations in NLRP3. Although somatic NLRP3 mosaicism is increasingly recognized, it remains unclear how variant allele…
Demeckova V, Demcakova V, Sedlakova-Kadukova J · 2025 · IEEE transactions on nanobioscience
Silver nanoparticles (AgNPs) are widely used for their antimicrobial properties but pose risks like environmental contamination and potential harm to human health. Nanoparticles' small size facilitates translocation within the body, often…
Shaik NF, Denison L, Venezia GMA et al. · 2026 · Journal of hospital medicine
Background Hospitalized patients often experience poor sleep, which is associated with worse health outcomes, increased rates of delirium, and readmissions. Objective To improve overnight sleep for clinically stable general neurology…
Zhang J, Wu Q, Chi D et al. · 2025 · Soil & tillage research
Phosphorus-loaded iron-modified biochar (Fe-BP) can be used as farmlands' slow-release phosphorus (P) fertilizer. This study aimed to explore the effects of Fe-BP on soil P composition, phosphatase activity, peanut P accumulation, and P…
Lukyanov AN, Vargin PN, Yushkov VA · 2025 · Atmospheric research
The eruption of the underwater volcano Hunga Tonga – Hunga Ha'apai (20.54° S, 178.3° W) on January 15, 2022, resulted in the first significant increase in the stratospheric water vapor content in the entire satellite observation era. This…
Ackermann DM, Medcalf E, Bracken K et al. · 2026 · Journal of clinical epidemiology
Objectives Digital reminders are widely used in clinical trials, but their design is rarely evidence-based. We evaluated the effectiveness of two types of digital reminders for trial task completion. Study design and setting This…
Hadi CE, Dailaty AA, Sobh AH et al. · 2025 · Preprint
Abstract Background Postoperative pulmonary complications (PPCs) remain a major determinant of morbidity after noncardiac surgery. Whether prior SARS-CoV-2 infection independently heightens PPC risk in the contemporary, highly vaccinated,…
Jones PAT, Brockwell E, Hassan A et al. · 2025 · British journal of sports medicine
Objective Recreational and elite athletes report avoiding breastfeeding when returning to physical activity following childbirth due to a perceived increased risk of injury; yet, there are no empirical data to support this relationship. We…
Sadowska-Klasa A, Bełdzińska-Gądek K, Klein-Awerjanow K et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Cytomegalovirus (CMV) pneumonia is a serious complication in immunocompromised patients, but its role in non-transplant populations remains unclear. Methods We analyzed CMV DNA in bronchoalveolar lavage (BAL) samples from 100…
Wöhner S, Jescheniak JD · 2025 · Preprint
The production of a word is delayed by the recent production of one or more semantically related words. This phenomenon, known as semantic interference, has been observed in picture naming tasks involving either large sets of pictures…
Murray RL, Baldwin D, Brain K et al. · 2026 · Thorax
Introduction Lung cancer screening (LCS) with low-dose CT offers a teachable moment for smoking cessation (SC), but the optimal way to implement SC within LCS is unclear. The Yorkshire Enhanced Stop Smoking (YESS) study assessed the…
Garrido-Bautista J, Ortega Z, Pérez-Jiménez A et al. · 2025 · Ecological and evolutionary physiology
AbstractClutch size variation may be adaptive in bird populations if parents lay a clutch size that maximizes offspring recruitment. Brood size manipulation experiments allow for testing the optimization of clutch size by studying the…
Brown N, King SW, Bagshaw O et al. · 2026 · Injury
Introduction The Ilizarov method is an established technique for complex cases. Decisions about circular frame removal are imprecise, with no fully reliable method to confirm union. Errors can lead to complications such as refracture,…