Longitudinal Analysis of Somatic Mosaicism and Clonal Hematopoiesis in Cryopyrin-Associated Periodic Syndrome.
Kato K; Honda Y; Kamatani T; Murakami K; Shimizu M; Komai T; Kanda H; Yasumura J · 2026 · Arthritis & rheumatology (Hoboken, N.J.)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Objective Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory disease caused by gain-of-function mutations in NLRP3. Although somatic NLRP3 mosaicism is increasingly recognized, it remains unclear how variant allele…
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Metadata source: Europe PMC · DOI 10.1002/art.43329