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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21374 results · page 657 of 713

Negative / Null Result ReportOpen accessMedicine

Association between Serum Vitamin D Levels and <i>VDR</i> <i>BsmI</i> Polymorphism in Temporomandibular Joint Dysfunction Patients (in the Iranian Population).

Mostafavi M, Rezazadeh F, Fattahi MJ et al. · 2026 · Journal of dentistry (Shiraz, Iran)

Background Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders. Purpose This study aimed to…

View details →DOI: 10.30476/dentjods.2025.106238.2644
Negative / Null Result ReportMedicine

The risk of type 1 diabetes mellitus after COVID-19 and influenza infection: A nationwide cohort and self-controlled case series study.

Ozaki K, Nishioka Y, Kamitani F et al. · 2026 · Diabetes research and clinical practice

It has been controversial whether COVID-19 increases the risk of new-onset type 1 diabetes mellitus. Using large-scale claims data, we found no statistically significant association between COVID-19 and incident type 1 diabetes mellitus in…

View details →DOI: 10.1016/j.diabres.2026.113366
Negative / Null Result ReportOpen accessMedicine

The association of pathological findings in HPV-31 positive women with high-grade squamous intraepithelial lesions.

Buran A, Altaş H, Özkaya Uçar Y et al. · 2026 · Journal of the Turkish German Gynecological Association

Objective To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and methods This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for…

View details →DOI: 10.4274/jtgga.galenos.2026.2025-12-2
Negative / Null Result ReportOpen accessMedicine

A high rate of falls and traumatic fractures occurs after extensor mechanism reconstruction: a cohort study including both allograft and synthetic mesh grafts.

Braun S, Selkridge I, Nocon A et al. · 2026 · Arthroplasty (London, England)

Background Extensor mechanism disruption following total knee arthroplasty (TKA) significantly impairs knee function and quality of life. Extensor mechanism reconstruction (EMR) is effective but carries risks, including post-operative…

View details →DOI: 10.1186/s42836-026-00393-8
Negative / Null Result ReportMedicine

rs6897932 (C>T) and rs987106 (A>T) variants in the <i>IL7RA</i> gene are correlated with the susceptibility and the clinical features of systemic lupus erythematosus.

Sarpeleh F, Ehtesham N, Mirjani R et al. · 2026 · Lupus

ObjectiveThe dysfunction of interleukin-7 receptor alpha (IL-7Rα), which is encoded by the IL7RA gene, has been implicated in the development of systemic lupus erythematosus (SLE). This study aimed to investigate the relationship between…

View details →DOI: 10.1177/09612033261429135
Negative / Null Result ReportOpen accessMedicine

Impact of weekend admission on in-hospital mortality in chronic kidney disease: a nationwide analysis of 184 299 hospitalisations in Poland (2017-2021).

Mazurek A, Jankowski M, Grudziąż-Sękowska J · 2026 · BMC nephrology

BACKGROUND: The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied…

View details →DOI: 10.1186/s12882-026-04885-2
Negative / Null Result ReportOpen accessMedicine

Plantar Heel Pain Is Not Associated With Fatty Infiltration of the Abductor Digiti Minimi Muscle on Magnetic Resonance Imaging: A Cross-Sectional Observational Study.

Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research

Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…

View details →DOI: 10.1002/jfa2.70155
Negative / Null Result ReportMedicine

Institutional educational climate and MIR examination outcomes: a multicenter ecological study in Spanish medical schools.

Millán J, Gal B, Esquerda M et al. · 2026 · BMC medical education

Background In Spain, access to specialized medical training is determined through a highly competitive national examination (MIR). While the educational climate of medical schools has been associated with students' learning outcomes and…

View details →DOI: 10.1186/s12909-026-09516-w
Negative / Null Result Report

Fast Food Consumption Habits Knowledge Attitudes and Their Association with Body Mass Index Among Health Sciences Students in Oman

Mahaboob L, Chehade H, Gnanamuthu SS et al. · 2026 · Preprint

Abstract Background Fast-food consumption has become increasingly prevalent among university students, contributing to unhealthy dietary patterns and rising obesity rates. Understanding students' fast-food consumption habits, knowledge,…

View details →DOI: 10.21203/rs.3.rs-9610403/v1
Negative / Null Result ReportMedicine

Relationship between <i>APOE</i> Genotype Status and Imaging Features in Patients with Alzheimer Disease Being Considered for Antiamyloid β Therapy.

Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology

Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…

View details →DOI: 10.3174/ajnr.a9056
Negative / Null Result ReportOpen accessMedicine

Intubation exposure associated with first-pass success - understanding practitioner-related characteristics in South African EMS.

Brown J, Abdullah N, Sobuwa S · 2026 · International journal of emergency medicine

BACKGROUND: Endotracheal intubation is a critical life-saving intervention in prehospital emergency care, yet evidence supporting its safe implementation by prehospital practitioners in lower- to middle-income countries remains limited.…

View details →DOI: 10.1186/s12245-026-01183-4
Negative / Null Result ReportMedicine

Ultrasound Findings After Uterine Artery Embolisation: Pictorial Essay and Clinical Validation.

Lukies M, Darby O, Wani S et al. · 2026 · Journal of medical imaging and radiation oncology

Uterine artery embolisation (UAE) is an evidence-based treatment for symptomatic fibroids and adenomyosis. Ultrasound is commonly utilised for assessment post UAE given its wide availability and low cost; however, contemporary studies…

View details →DOI: 10.1111/1754-9485.70132
Negative / Null Result ReportOpen accessMedicine

Salivary decorin as a potential noninvasive biomarker in chronic kidney disease: a comparative study with serum levels.

Karatutlu AS, Karatutlu MA, Aydin S · 2026 · Renal failure

Chronic kidney disease (CKD) is characterized by progressive renal fibrosis and irreversible loss of kidney function. Decorin, an extracellular matrix proteoglycan with antifibrotic properties, may reflect underlying fibrotic activity and…

View details →DOI: 10.1080/0886022x.2026.2689757
Negative / Null Result ReportOpen accessMedicine

Associations of physical fitness with sleep quality and anxiety Among university students: a cross-sectional regression analysis.

Xu G, Li X, Song G et al. · 2026 · Frontiers in sports and active living

Background Poor sleep quality and anxiety are prevalent among university students and pose growing public health concerns. Physical fitness is often assumed to be associated with better sleep and mental health outcomes; however, evidence…

View details →DOI: 10.3389/fspor.2026.1795033
Negative / Null Result ReportMedicine

Does dietary acid load affect muscle strength and physical performance in young adult women? A single-center experience.

Tel Adigüzel K, Atasoy S, Güler B et al. · 2026 · Nutrition and health

BackgroundMuscle strength is a key determinant of functional capacity and quality of life, influenced by various modifiable factors including nutrition. Emerging evidence suggests a potential link between dietary acid load and…

View details →DOI: 10.1177/02601060261462777
Negative / Null Result ReportOpen accessMedicine

Investigation of the relationship between the cephalic index and the tentorium cerebelli: A retrospective study.

Vatansever A, Erçakmak Güneş B, Günenç Beşer C et al. · 2026 · Medicine

The cerebellar tentorium, composed of 2 laminae of dura mater, is an essential structure that separates the posterior and middle cerebral fossae. As it has a dural sinus within its 2 laminae, it carries significant risk potential. Cranium…

View details →DOI: 10.1097/md.0000000000049179
Negative / Null Result ReportMedicine

Changes in myeloid-derived suppressor cells and cytokine expression during mother-to-child transmission prevention in HBeAg-positive pregnant women with chronic hepatitis B.

Pan S, Xiao L, Li Y et al. · 2026 · BMC infectious diseases

Objective The objective of this study was to investigate the changes of Myeloid-derived suppressor cells (MDSCs) and cytokines expression during mother-to-child blockade in chronic HBV infected patients. Method This was a single-center,…

View details →DOI: 10.1186/s12879-026-13594-y
Negative / Null Result Report

Confounding Masks the Relationship Between Thiamine and Quality of Life in Pediatric Congenital Heart Disease: A Multivariable Analysis

Amelia P, Tobing TC, Adriansyah R et al. · 2026 · Preprint

Abstract Background: Children with congenital heart disease (CHD) are at risk of impaired quality of life (QoL) due to hemodynamic burden and nutritional disturbances. Thiamine plays an essential role in myocardial energy metabolism, but…

View details →DOI: 10.21203/rs.3.rs-9513847/v1
Negative / Null Result ReportMedicine

The diameter of malformation capillaries does not influence the efficacy of photodynamic therapy for facial port-wine stains: a pilot study.

Hao L, Ju W, Huang Y · 2026 · The Journal of dermatological treatment

Background Photodynamic therapy (PDT) is an effective treatment for port-wine stains (PWS). However, the relationship between the diameter of malformed capillaries and the efficacy of PDT in PWS has been rarely studied. Objective This…

View details →DOI: 10.1080/09546634.2026.2685355
Negative / Null Result ReportMedicine

Structural-functional dissociation in acute Bell's palsy: a comparative study of high-resolution ultrasound and electrodiagnostic testing.

El Habashy HR, Ahmed SM, Al Salmawy DA et al. · 2026 · Neurological research

Background Bell's palsy (BP) is the most common acute peripheral mononeuropathy worldwide. While electrodiagnostic studies are established tools for functional assessment, high-resolution ultrasonography (HRUS) has emerged as a…

View details →DOI: 10.1080/01616412.2026.2680967
Negative / Null Result ReportMedicine

Emotion Perception in Behavioral Variant Frontotemporal Dementia and Alzheimer Disease: The Parahippocampal Conundrum.

Morais RF, Duro D, Pires R et al. · 2026 · Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology

Background Emotion perception is the capacity that enables humans to correctly identify the cues that guide interpersonal interactions, forming the basis for social behavior. The parahippocampal cortex may contribute to emotion perception…

View details →DOI: 10.1097/wnn.0000000000000420
Negative / Null Result ReportOpen accessMedicine

Changes in Upper Airway Anatomy and Apnea-Hypopnea Index in Patients with Obstructive Sleep Apnea Undergoing Bariatric Surgery: A Pilot Study.

Nithya M, Titiyal R, Ajayababu A et al. · 2026 · Journal of clinical medicine

Background: Obstructive sleep apnea (OSA) is common in individuals with obesity, largely due to increased soft tissue causing upper airway narrowing. However, mechanisms of OSA improvement following weight loss are incompletely understood,…

View details →DOI: 10.3390/jcm15114038