Comparison of efficacy and safety of vildagliptin 50 mg tablet twice daily and vildagliptin 100 mg sustained release once daily tablet on top of metformin in Indian patients with Type 2 diabetes mellitus: A randomized, open label, Phase IV parallel group, clinical trial
Rudra Paul; Arijit Ghosh; Nilanjan Sengupta; Pranab Kumar Sahana · 2022 · National Journal of Physiology, Pharmacy and Pharmacology
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: Type 2 diabetes mellitus (DM) is mainly due to multifactorial of which insulin resistance and deficiency in the incretion are two important pathophysiological factors. Vildagliptin, an oral hypoglycemic agent, acts by inhibiting dipeptidyl peptidase-4 enzyme, often uses as a first line drug along with metformin to enhance outcome. Aim and Objective: The aim of this study was to compare the effectiveness and safety of vildagliptin 50 mg twice daily dose with vildagliptin 100 mg sustained release tablet (SR) once daily in Type 2 DM patients and uncontrolled with metformin monotherapy
Abstract by Rudra Paul; Arijit Ghosh; Nilanjan Sengupta; Pranab Kumar Sahana, National Journal of Physiology, Pharmacy and Pharmacology (2022) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.5455/njppp.2022.12.062851202217862022