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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21350 results · page 581 of 712

Negative / Null Result ReportMedicine

Nanopatterns on silica scales of Mallomonas (Chrysophyceae, Stramenopiles): Unraveling UV resistance potential and diverse response to UVA and UVB radiation

Němcová Y, Knotek P, Jadrná I et al. · 2024 · Journal of phycology

Mallomonas thrive primarily in freshwaters and dominate plankton communities, especially in oligotrophic waters. The cells have a siliceous cell covering of regularly arranged scales. Despite their ecological importance, the intricate…

Negative / Null Result Report

Migration strategies of a high-latitude breeding songbird ( Setophaga coronata coronata ) revealed using multi-sensor geolocators and stable isotopes

Szarmach SJ, Beam JK, Moore M et al. · 2024 · Preprint

ABSTRACT Seasonal migration allows animals to use habitat where conditions are unfavorable for part of the year but may constrain breeding ranges due to the costs of longer migrations as ranges expand poleward. In species with large…

View details →DOI: 10.1101/2024.10.09.617415
Negative / Null Result ReportMedicine

Exposure to structural racism-related state laws is associated with worse cardiovascular health among US adults, BRFSS 2011 and 2013.

Needham BL, Dokshina D, Ali T et al. · 2025 · American journal of epidemiology

The objective of this study was to determine whether exposure to structural racism-related state laws is associated with cardiovascular health among a racially and ethnically diverse sample of US adults. Data were from the Database of…

View details →DOI: 10.1093/aje/kwae176
Negative / Null Result ReportMedicine

Expression of CD226 on γδ T cells is lower in advanced chronic lymphocytic leukemia and correlates with IgA, IgG and LDH levels.

Zarobkiewicz MK, Lehman N, Kowalska W et al. · 2025 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Background Gamma-delta (γδ) T cells comprise an important subset of human T cells, responding to viral and bacterial infections, and are significant for cancer immunosurveillance. Human γδ T cells are divided into 5 major subsets, namely…

View details →DOI: 10.17219/acem/186335
Negative / Null Result ReportMedicine

Exploring fonts as retrieval cues in text-based learning.

Krieglstein F, Jansen S, Meusel F et al. · 2024 · Acta psychologica

A growing body of research focuses on optimizing retrieval processes to help learners recall information from memory. The context-dependent memory effect suggests that information retrieval is more effective when the retrieval context…

View details →DOI: 10.1016/j.actpsy.2024.104606
Negative / Null Result ReportMedicine

Inter-Strain Differences in the Lumbar Spinal Cord Anatomy and Neuromorphology: Wistar Versus Dark Agouti Rats.

Veshchitskii A, Shkorbatova P, Efimova E et al. · 2024 · The Journal of comparative neurology

Rat strains differ in physiology, behavior, and recovery after central nervous system injury. To assess these differences, we compared the gross and local anatomy and neuromorphology of the lumbar spinal cord of the Wistar and Dark Agouti…

View details →DOI: 10.1002/cne.25673
Negative / Null Result ReportOpen accessMedicine

Low neuroticism as an indicator of resilience: a longitudinal study of Danish soldiers before, during and after deployment.

Melkevik O, Jeppesen LS, Folke S et al. · 2025 · European journal of psychotraumatology

Background : Posttraumatic stress disorder (PTSD) is a serious and debilitating condition among military veterans. Exposure to potentially traumatic events (PTEs) may lead to PTSD and PTE sensitivity may be influenced by the personality…

View details →DOI: 10.1080/20008066.2025.2476810
Negative / Null Result Report

From In Vitro Promise to In Vivo Reality: An Instructive Account of Infection Model Evaluation of Antimicrobial Peptides

Carrera-Aubesart A, Li J, Contreras E et al. · 2024 · Preprint

Antimicrobial peptides (AMPs) are regarded as a promising alternative to traditional antibiotics in the face of ever-increasing resistance. Our research has focused on crotalicidin (Ctn), an AMP from a snake venom, and a fragment thereof,…

View details →DOI: 10.20944/preprints202408.0325.v1
Negative / Null Result ReportMedicine

Seagrass influence on mitigating ocean acidification and warming impacts on tropical calcifying macroalgae.

Awaluddin K, Mayfield AB, Tew KS et al. · 2025 · Marine environmental research

Ocean acidification (OA) and warming pose significant threats to marine ecosystems, particularly by reducing calcium carbonate availability for marine calcifiers. Given that seagrasses can capture and store excess carbon, this study aimed…

View details →DOI: 10.1016/j.marenvres.2025.106976
Negative / Null Result ReportOpen accessMedicine

Burns results in profound muscle protein wasting in Sprague Dawley rats that is not resolved using the lipolysis inhibitor, acipimox.

Vardarli E, Bhattarai N, El Ayadi A et al. · 2025 · PloS one

Introduction Major burns results in the rapid and profound accumulation of lipid in peripheral tissues, but its impact on muscle metabolic function is unclear. Given previous reports demonstrating that lipid oversupply compromises…

View details →DOI: 10.1371/journal.pone.0323640
Negative / Null Result ReportMedicine

Benefits of a group-based running session on feelings of energy and fatigue: No augmenting effect of green exercise during the defoliation season.

Legrand FD, Jeandet P, Polidori G et al. · 2025 · Psychology of sport and exercise

This randomized controlled trial investigated the impact of a brief session of group-based running on feelings of energy and fatigue, comparing exercise in a local nature reserve versus an outdoor built environment, and a sedentary control…

View details →DOI: 10.1016/j.psychsport.2024.102760
Negative / Null Result ReportOpen accessMedicine

Mediating Effect of IADL and Depression in the Relationship Between Ability to Perform Movements and Death Preparation in Elderly with Osteoarthritis or Rheumatoid Arthritis.

Kwon M, Kim SA, Kim J · 2025 · Healthcare (Basel, Switzerland)

Background/Objectives : This study investigated the mediating effects of instrumental activities of daily living (IADL) and depression on the relationship between the ability to perform movements and death preparation among older adults…

View details →DOI: 10.3390/healthcare13050513
Negative / Null Result ReportOpen accessMedicine

Correlates of Eccentric Metrics and Sprint Acceleration and Deceleration Performance in University Athletes.

Gordon G, Nadar T, Green A · 2026 · Journal of functional morphology and kinesiology

Background : Sprint performance, including acceleration, maximal velocity and deceleration, is crucial for athletic success in field and court-based sports; however, deceleration remains understudied despite its role in change of direction…

View details →DOI: 10.3390/jfmk11020155
Negative / Null Result ReportOpen accessMedicine

Combining Endoscopic Submucosa Dissection and Endoscopic Full-Thickness Resection for Resection of a Gastric Schwannoma Mimicking Gastrointestinal Stroma Tumor.

Kormann S, Semadeni GM, Weber M et al. · 2024 · ACG case reports journal

Subepithelial gastric tumors are a diagnostic challenge. Endoscopic ultrasound allows differentiation. Lesions originating from the submucosal layer can be resected using endoscopic submucosal dissection (ESD). Surgery or endoscopic…

View details →DOI: 10.14309/crj.0000000000001440
Negative / Null Result ReportOpen accessMedicine

Inadequacy of interventions to eliminate or reduce violence against healthcare professionals by patients and/or their relatives.

Yöyen E, Barış TG · 2026 · World journal of psychiatry

Workplace violence (Type II), which is defined as verbal, physical and sexual assault behaviour directed at healthcare workers by patients and their relatives, is a complex concept arising from a variety of individual, social, economic,…

View details →DOI: 10.5498/wjp.v16.i2.113936
Negative / Null Result ReportMedicine

Multi-parametric magnetic resonance imaging of the prostate in Victoria, Australia; unintended consequences of changing Medicare Benefits Schedule access.

Gordon P, Urquhart E, Oad S et al. · 2024 · Australian health review : a publication of the Australian Hospital Association

Objective To assess whether prostate biopsy rates have altered with the July 2018 change in Australian Medicare Benefits Schedule (MBS) rebates supporting multiparametric magnetic resonance imaging (mpMRI) for diagnosing prostate cancer.…

View details →DOI: 10.1071/ah24024
Negative / Null Result ReportOpen accessMedicine

Attachment representations in Afghan refugees undergoing psychological treatment: a pilot study.

Egger T, Gander M, Dumser B et al. · 2025 · European journal of psychotraumatology

Background: Refugees are at elevated risk of trauma-related disorders. Unresolved attachment is a vulnerability factor for post-traumatic stress, yet its role in Afghan refugees remains underexplored. This is the first study to assess…

View details →DOI: 10.1080/20008066.2025.2582456
Negative / Null Result ReportOpen accessMedicine

A Case of Unexpected Peritoneal Carcinomatosis From Colon Cancer Detected After Robot-Assisted Radical Cystectomy for Advanced Bladder Cancer.

Ito K, Yamashita R, Kasai S et al. · 2026 · IJU case reports

Introduction Peritoneal carcinomatosis in patients with advanced bladder cancer is a rare but lethal event following robot-assisted radical cystectomy (RARC). We report a case of an unusual clinical course in which peritoneal dissemination…

View details →DOI: 10.1002/iju5.70155
Negative / Null Result ReportMedicine

Integrating vision and somatosensation does not improve the accuracy and response time when estimating area and perimeter of rectangles in primary school.

Leukel C, Loibl K, Leuders T · 2024 · Trends in neuroscience and education

Background Problem-solving and learning in mathematics involves sensory perception and processing. Multisensory integration may contribute by enhancing sensory estimates. This study aims to assess if combining visual and somatosensory…

View details →DOI: 10.1016/j.tine.2024.100238
Negative / Null Result ReportOpen accessMedicine

Conscious and Resilient? Associations Between Temperament, Emotional Awareness, and Emotion Regulation Strategies in Youth.

Struyf S, Koster EHW, Van Beveren ML et al. · 2026 · Psychologica Belgica

Introduction Emotion regulation (ER) plays a crucial role in children and adolescents' emotional well-being. However, the use of adaptive strategies often remains challenging during early adolescence, partly because cognitive functions…

View details →DOI: 10.5334/pb.1399
Negative / Null Result ReportMedicine

Seasonal Sulfur Redox Cycling in Two Constructed Wetlands with Insight on How They Age.

Lindelien CM, Xu X, Knox AS et al. · 2024 · Bulletin of environmental contamination and toxicology

Long-term metal remediation in wetland treatment systems (WTSs) involves facilitating dissimilatory sulfate reduction to produce sulfide and mineralize metals in deep sediments. We evaluated seasonal sulfur cycling in two constructed…

View details →DOI: 10.1007/s00128-024-03942-6
Methods Dead-EndOpen accessMedicine

Design, power, and alpha levels in randomized phase II oncology trials.

Haslam A, Olivier T, Prasad V · 2023 · ESMO open

Background The statistical plan of a phase II trial should balance minimizing the premature termination of potentially beneficial therapies (i.e. false negatives) and the further, costly testing of ineffective drugs (i.e. false positives).…

View details →DOI: 10.1016/j.esmoop.2022.100779
Negative / Null Result ReportMedicine

Nanopatterns on silica scales of Mallomonas (Chrysophyceae, Stramenopiles): Unraveling UV resistance potential and diverse response to UVA and UVB radiation.

Nemcova Y, Knotek P, Jadrná I et al. · 2024 · Journal of phycology

Mallomonas thrive primarily in freshwaters and dominate plankton communities, especially in oligotrophic waters. The cells have a siliceous cell covering of regularly arranged scales. Despite their ecological importance, the intricate…

View details →DOI: 10.1111/jpy.13496