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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 566 of 725

Negative / Null Result ReportOpen accessComputer Science

Not All Queries Need Rewriting: When Prompt-Only LLM Refinement Helps and Hurts Dense Retrieval

Varun Kotte · 2026 · arXiv

Prompt-only, single-step LLM query rewriting, where a rewrite is generated from the query alone without retrieval feedback, is commonly used in production RAG pipelines, but its effect on dense retrieval is poorly understood. We present a systematic empirical study across three BEIR benchmarks, two dense retrievers, and multiple training configurations, and find strongly domain-dependent behavior: rewriting degrades nDCG@10 by 9.0 percent on FiQA, improves it by 5.1 percent on TREC-COVID, and has no significant effect on SciFact. We identify a consistent mechanism: degradations co-occur with r

Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Does Antibiotic Resistance Evolve in Hospitals?

Anna Seigal, Portia Mira, Bernd Sturmfels et al. · 2016 · arXiv

Nosocomial outbreaks of bacteria are well-documented. Based on these incidents, and the heavy usage of antibiotics in hospitals, it has been assumed that antibiotic resistance evolves in hospital environments. To test this assumption, we studied resistance phenotypes of bacteria collected from patient isolates at a community hospital over a 2.5-year period. A graphical model analysis shows no association between resistance and patient information other than time of arrival. This allows us to focus on time course data. We introduce a Hospital Transmission Model, based on negative binomial delay

Negative / Null Result ReportOpen accessPhysics

Double Bars, Inner Disks, and Nuclear Rings in Early-Type Disk Galaxies

Peter Erwin, Linda S. Sparke · 2002 · arXiv

We present results from an imaging survey of an unbiased sample of thirty-eight early-type (S0--Sa), low-inclination, optically barred galaxies in the field. Our goal was to find and characterize central stellar and gaseous structures: secondary bars, inner disks, and nuclear rings. Bars inside bars are surprisingly common: at least one quarter of the sample galaxies (possibly as many as 40%) are double-barred, with no preference for Hubble type or the strength of the primary bar. A typical secondary bar is ~12% of the size of its primary bar and 240--750 pc in radius. We see no significant ef

Negative / Null Result ReportOpen accessPhysics

The Outer Cut-Off of the Giant Planet Population and the 6pc-Survey

D. Apai, M. R. Meyer, P. Hinz et al. · 2007 · arXiv

We present results from two high-contrast imaging surveys that exploit a novel technique, L-band angular differential imaging. Our first survey targeted 21 young stars in the Beta Pic and Tuc-Hor moving groups with VLT/NACO reaching typical sensitivities of 20 AU. The statistical analysis of the null result demonstrates that the giant planet population is truncated at 30 AU or less (90% confidence level). Our second, on-going MMT/Clio survey utilizes the unique sensitivity achieved in the L-band for old planets to probe all M-dwarf stars within 6 pc. The proximity of these targe

Negative / Null Result ReportMedicine

Assessment of Fixed Bearing and Rotating Platform Total Knee Arthroplasty Designs Using the Patient Knee Implant Performance Scoring System: Post-hoc Pooled Analysis of Data From Two Prospective, International, Multi-centre, Non-randomised Studies.

Mohammed Abdul, Bernard, Yates · 2026 · Cureus

Background The optimal choice of polyethylene insert in total knee arthroplasty (TKA) continues to cause contention. Rotating platform bearings (RP) have theoretical advantages but have failed to demonstrate a functional difference…

View details →DOI: 10.7759/cureus.109613
Negative / Null Result ReportMedicine

Natural versus artificial cycle for endometrial preparation in ovulatory women undergoing frozen-thawed embryo transfer: a randomised controlled trial.

Geysenbergh, Debrock, Lie Fong et al. · 2026 · Human reproduction (Oxford, England)

Does a natural cycle result in higher clinical pregnancy rates (CPR) with foetal heartbeat compared to an artificial cycle for frozen-thawed embryo transfer (FET) preparation in ovulatory women? The CPR with foetal heartbeat did not differ…

View details →DOI: 10.1093/humrep/deag095
Negative / Null Result ReportMedicine

Pharmacogenomic Stratification for Oncology Drug Repurposing: An Exposure Target Context Eligibility Framework.

El-Tanani, Wali, Rabbani et al. · 2026 · Pharmaceuticals (Basel, Switzerland)

In spite of plausible biology, the majority of oncology trials involving drug repurposing have failed to demonstrate any efficacy. Numerous factors can potentially cause failure, including issues with dosing, drug strength, the trial…

View details →DOI: 10.3390/ph19060957
Negative / Null Result ReportOpen accessBiology (General)

Exogenous MnSO 4 Improves Productivity of Degenerated Volvariella volvacea by Regulating Antioxidant Activity

Qiaoli Wang, Wenpei Wang, Yonghui Wang et al. · 2024 · Journal of Fungi

Manganese is one of the trace elements necessary for organisms to maintain normal biological activities and is also a cofactor for manganese superoxide dismutase (Mn-SOD) and manganese peroxidase (MnP). In order to find a simple and effective method to rejuvenate the degenerated V. volvacea strains, we explored the effect of the exogenous addition of MnSO 4 on the antioxidant vigour and productivity of degenerated strains of V. volvacea . The results showed that the exogenous MnSO 4 had no significant effect on the non-degenerated strain T0, but it could effectively increase the mycelial growt

View details →DOI: 10.3390/jof10120825
Negative / Null Result ReportOpen accessScience

Body condition score at lambing did not affect the resumption of ovarian and estrous activity in lactating Pelibuey ewes

Karlos Edmundo Orozco Durán, José Segura Correa, Jessica Herrera Ojeda et al. · 2022 · Nova Scientia

The aim of the study was to evaluate the effect of body condition score (BCS) at lambing over the resumption of ovarian and estrous postpartum activity in lactating Pelibuey ewes. Twenty ewes were assigned to two groups, according to the BCS at lambing: Low BCS (LBC, n = 10) and High BCS (HBC, n = 10). Ovarian and estrous activities were daily monitored from day 3 postpartum until the first estrous or 90 days postpartum. Continuous variables were analyzed using Student´s t test and binary responses with the exact Fisher test. No significant effect of BCS at lambing on ewes in estrous, lambing

View details →DOI: 10.21640/ns.v14i28.2965
Negative / Null Result ReportOpen accessEnvironmental sciences

A biomarker assessment of pesticide toxicity in endemic, native peregrine, and invasive earthworm species from the Muthalamada mango plantations, Kerala, India

Chandini Palakkunnel Kuttappan, Sasankan Prasanth Narayanan, Syamkumar Reghu Nandanan Pillai et al. · 2025 · Natural Built Social Environment Health

This study assessed the toxic effects of pesticide exposure on four earthworm species: Perionyx excavatus Perrier, 1872; Megascolex konkanensis Fedarb, 1898; Dichogaster affinis (Michaelsen, 1890); and Metaphire houlleti (Perrier, 1872). The organisms were exposed to pesticide-treated soil. Biomass reduction, immunotoxicity, and enzyme biomarkers were used as endpoints. Among the tested species, M. konkanensis, a native species, appeared more sensitive than the others. In biomass tests, chlorpyrifos showed no significant effect on final body mass (p > 0.05). P. excavatus showed a significant r

View details →DOI: 10.63095/nbseh.25.850535
Negative / Null Result ReportOpen accessChemistry

Influence de l’Agitation Mécanique sur les Reactions Chimiques Oscillantes en Présence d’Oxygène ou d’Azote

Vincent J. Farage, Désimir Janjic · 1981 · CHIMIA

In certain cases, and particularly for the BrO3-/Ce4+/malonic acid system, oxygen seems to inhibit oscillations and the mechanical stirring in a N2 atmosphere has no significant effect on the oscillations. However, for the BrO3-/Ce4+/Cyclohexanon and BrO3-/Ce4+/Cyclopentanon systems under specific experimental conditions, stirring plays a determining part and oxygen has no notable effect on the oscillations.

View details →DOI: 10.2533/chimia.1981.289
Negative / Null Result ReportOpen accessAccounting. Bookkeeping

PENGARUH GOOD GOVERNMENT GOVERNANCE DAN UKURAN LEGISLATIF TERHADAP KINERJA PEMERINTAH DAERAH (STUDI PADA PEMERINTAH PROVINSI DI INDONESIA)

Hutapea Lastiar Hutapea, Aristanti Widyaningsih · 2017 · Jurnal ASET (Akuntansi Riset)

Abstract. The variables tested in the study consist of Good Government Governance measured by the rank of Indonesia Governance Index (IGI) and the size of the legislative by using the number of members of the provincial parliament, and also local government performance measured by three proxies, the GDP per capita, Poverty Rates, and independence Ratios. The study is conducted in 33 provinces in Indonesia in 2012. The results show that there is no significant effect of good government governance on local government performance by proxy of GDP per capita. There is significant impact of good gov

View details →DOI: 10.17509/jaset.v9i1.5446
Negative / Null Result ReportOpen accessEngineering (General). Civil engineering (General)

The Effect of Inclination Angle on Critical Heat Flux in a Locally Heated Liquid Film Moving Under the Action of Gas Flow in a Mini-Channel

Tkachenko Egor M., Zaitsev Dmitry V. · 2016 · MATEC Web of Conferences

Intensively evaporating liquid films moving under the action of the cocurrent gas flow in a microchannel are promising for the use in modern cooling systems of semiconductor devices with high local heat release. This work has studied the dependence of the critical heat flux on the inclination angle of the channel. It has been found that the inclination angle in the plane parallel to the flow has no significant effect on the critical heat flux. Whereas the inclination angle in the plane perpendicular to the flow, on the contrary, significantly changes the value of the critical heat flux. Howeve

View details →DOI: 10.1051/matecconf/20167201114
Negative / Null Result ReportOpen accessReproduction

Artificial lactation by exogenous hormone treatment in non-pregnant sows

Michiko NOGUCHI, Takehito SUZUKI, Reiichiro SATO et al. · 2020 · The Journal of Reproduction and Development

This study aimed to determine if lactation can be induced by exogenous hormonal treatment in non-pregnant sows. In experiment 1, pseudopregnant animals were divided into four groups and given: 1) 5 mg of estradiol dipropionate (EDP) 5 days before (n = 4), 2) 5 mg of EDP 10 days before (n = 3), 3) 10 mg of EDP 5 days before (n = 3) or 4) 10 mg of EDP 10 days (n = 3) before PGF2α treatment. Artificial lactation was induced in seven pseudopregnant sows (53.8%) by exogenous hormonal treatment. There was no significant effect of either an increased EDP dosage or interval from the EDP treatment to P

View details →DOI: 10.1262/jrd.2020-034
Negative / Null Result ReportOpen accessBusiness

The effect of inflation, profit-loss sharing loan, and capital adequacy towards performance of Indonesian Islamic banks

Luksi Visita · 2019 · DIJB (Diponegoro International Journal of Business)

The purpose of this study is to observe the impact of inflation, profit-loss sharing loan, and capital adequacy towards performance of Islamic banks in Indonesia. This study utilizes longitudinal study from 2010 to 2018 towards Islamic Commercial Banks and Sharia Business Units that are listed in Indonesia. Using pool-time series data, the variables studied are inflation, capital adequacy ratio (CAR), profit-loss sharing loan, and return on assets (ROA). The result shows that only inflation has no significant effect on performance. Capital adequacy affects positively significant, while profit-

View details →DOI: 10.14710/dijb.2.2.2019.57-63
Negative / Null Result ReportOpen accessHistory of scholarship and learning. The humanities

The effect of environmental values, beliefs, and norms on social entrepreneurial intentions among Chinese university students

Qing Yang, Abdullah Al Mamun, Siyu Long et al. · 2024 · Humanities & Social Sciences Communications

Abstract This study explores the factors influencing university students’ social entrepreneurial intentions based on the values-beliefs-norms theory. Data were collected from 769 Chinese university students through online surveys. The hypotheses were tested using partial least squares-structural equation modeling. The results confirmed the positive influence of altruistic and traditional values on normative beliefs. Awareness of the consequences and attribution of responsibility had no significant effect on personal norms among university students, which have been discussed in-depth in relatio

View details →DOI: 10.1057/s41599-024-03501-8
Negative / Null Result ReportOpen accessBiotechnology

Effect of different ultra-high pressure treatment on the quality of jujube wine

HUANG Weijing, CAI Wenchao, CUI Mengjun, WANG Yurong, SHAN Chunhui, GUO Zhuang · 2024 · Zhongguo niangzao

In order to investigate the effect of ultra-high pressure on the quality of jujube wine, the jujube wine prepared by Saccharomyces cerevisiae HBUAS61676 was treated at a pressure of 50-600 MPa, and the changes of physicochemical indexes, color, taste, and volatile flavor of jujube wine after different pressure treatments were studied. The results showed that ultra-high pressure treatment had no significant effect on the pH of jujube wine (P>0.05), but significantly affected the soluble solid content and the alcohol content (P<0.05). It could significantly affect the color of jujube wine (P<0.0

View details →DOI: 10.11882/j.issn.0254-5071.2024.12.034
Negative / Null Result ReportOpen accessFinance

Lemahnya Signifikansi Sistem Pengendalian Internal untuk Peningkatan Kualitas Laporan Keuangan Pemerintah Daerah

Riana Mayasari · 2022 · Jurnal Riset dan Aplikasi: Akuntansi dan Manajemen

This study aimed to determine the effect of internal control on the financial report’s quality. This research method was quantitative descriptive. Data were collected using documentation and literature study. This study used purposive sampling with total sample of 34 Local Governments on the Kalimantan Island. The data analysis technique used linear regression. The results of statistical tests showed that the internal control system had no significant effect on the quality of financial reports in regency/ city governments in Kalimantan. Abstrak Penelitian ini bertujuan mengetahui pengaruh peng

View details →DOI: 10.33795/jraam.v6i1.011
Negative / Null Result ReportOpen accessAgriculture (General)

Cotton Yield and Water Productivity Affected by Conservation Tillage and Irrigation Methods in Cotton-Wheat Rotation

S Afzalinia, A Ziaee · 2020 · Journal of Agricultural Machinery

In this study, the effect of conservation tillage and irrigation methods on the soil properties, cotton yield, and water productivity was evaluated in a wheat-cotton cropping system in the form of a split-plot experimental design. The main plots were irrigation using the three methods including surface irrigation, drip tape irrigation, and sprinkler irrigation. Tillage methods including zero tillage, reduced tillage, and conventional tillage were considered as subplots in this research. Results showed that tillage methods had no significant effect on cotton yield; whereas, the cotton yield was

View details →DOI: 10.22067/jam.v10i1.76229
Negative / Null Result ReportOpen accessBiology (General)

Studies on the population of methane-oxidizing bacteria and methane-oxidizing activity in Huangsong rice-field soil

CHEN Zhong-yun, MIN Hang, WU Wei-xiang et al. · 2001 · 浙江大学学报. 农业与生命科学版

The populations of methane-oxidizing bacteria were analyzed in Huangsong soils with various plant-cover, using Hungate anaerobic technique and chromatographic monitoring method. The results showed that the population of methane-oxidizing bacteria ranged 10 7 -10 8 cfu/g dried soil with different plant-cover. The various plant-cover on soil seemed to have no significant effect on the population of methane-oxidizing bacteria, but to have noteworthy effect on the methane-oxidizing activity in soil sampies. The variation of the population of methane-oxidizing bacteria had no significant effect on

View details →DOI: 10.3785/1008-9209.2001.05.0546
Negative / Null Result ReportOpen accessMicrobiology

Effect of zero-valent iron on Rhizobium sp. cells isolated from cadmium-contaminated sites after remediation by zero-valent iron

Nuiyen Aussanee, Khumin Vinta, Wichai Siriwan · 2025 · BIO Web of Conferences

Cadmium contamination found in paddy fields in the Maesot District of Tak Province, Thailand. This area was remediated using 50mg/L of ZVI. The study aimed to isolate and identify soil bacteria in the soil and rice roots and to investigate ZVI’s effect on the isolated bacterial cells. The results indicated no significant difference in soil bacteria content before and after remediation at the 95% confidence level. Twelve isolates of nitrogen-fixing bacteria were obtained. Those isolates could grow at high concentrations of 300 mg/L of ZVI. RH17 had a high tolerance for TSA with 300 mg/L of ZVI

View details →DOI: 10.1051/bioconf/202516403001
Negative / Null Result ReportOpen accessFood processing and manufacture

Chemical Diversity of Fuzhuan Brick Teas from Hunan and Shaanxi

ZHANG Ning, YU Shilan, YAN Haoyi, ZHANG Yunjun, HAN Xiaoyu, REN Hongyu, CHEN Yuqing, LING Tiejun, AN Maoqiang · 2024 · Shipin Kexue

This study aimed to explore the diversity of metabolites and compare the metabolite profiles of Fuzhuan brick teas from Hunan and Shaanxi, to find out the difference in chemical components between fresh tea leaves and Fuzhuan brick tea and to identify the metabolites from fungi in Fuzhuan brick tea. Metabolomic studies on fresh tea leaf samples, Hunan and Shaanxi Fuzhuan brick teas and fungi from them were performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and molecular networks of characteristic metabolites. The results showed no significant difference between Hunan and

View details →DOI: 10.7506/spkx1002-6630-20231108-066
Negative / Null Result ReportOpen accessSurgery

Incidence, Risk Factors, and Prevention Strategy for Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery

Tsuyoshi Sakuma, Toshiaki Kotani, Tsutomu Akazawa et al. · 2021 · Spine Surgery and Related Research

Introduction: Proximal junctional kyphosis (PJK) is an acute complication of adult spinal deformity (ASD) surgery and may require re-operation because of proximal junctional failure (PJF). PJK causes and prevention strategies remain unknown. This study aimed to investigate the differences in the backgrounds of patients with PJK, compared to those without PJK, in ASD surgery. Methods: We included data from 86 patients who underwent ASD surgery between 2012 and 2018. There were 40 patients (46.5%) with PJK; 46 patients did not have PJK until the last follow-up. We evaluated patient demographics,

View details →DOI: 10.22603/ssrr.2020-0093
Negative / Null Result ReportOpen accessBiology (General)

Disruption of the BMEI0066 gene attenuates the virulence of Brucella melitensis and decreases its stress tolerance

Xinglin Zhang, Jie Ren, Na Li, Wenjuan Liu, Qingmin Wu · 2009 · International Journal of Biological Sciences

Brucella melitensis is a facultative intracellular pathogen. An operon composed of BMEI0066, which encodes a two-component response regulator CenR, and BMEI0067, which encodes a cAMP-dependent protein kinase regulatory subunit, has been predicted to exist in many bacterial species. However, little is known about the function of this operon. In order to characterize this operon and assess its role in virulence, we constructed a marked deletion mutant of BMEI0066. The mutant was less able to withstand hyperosmotic conditions than wild-type (16M), but showed no significant difference with 16M whe

Negative / Null Result ReportOpen accessInternal medicine

Impact of acute kidney injury in deceased donors with high Kidney Donor Profile Index on posttransplant clinical outcomes: a multicenter cohort study

Woo Yeong Park, Yoon Kyung Chang, Young Soo Kim et al. · 2021 · Kidney Research and Clinical Practice

Background This study evaluated the impact of acute kidney injury (AKI) on posttransplant clinical outcomes for deceased donor (DD) kidney transplantation (KT) using the Kidney Donor Profile Index (KDPI) system. Methods Overall, 657 kidney transplant recipients (KTRs) receiving kidneys from 526 DDs from four transplant centers were included. We divided them into the high and low KDPI donor groups by 65%, the KDPI score, and both groups were subdivided into the AKI-DDKT and non-AKI-DDKT subgroups according to AKI in DDs. Results There was no significant difference in the incidence of delayed gr

View details →DOI: 10.23876/j.krcp.20.083
Negative / Null Result ReportOpen accessHuman anatomy

New approach to morphometric analysis of Huschke’s foramen

H. Çetin, S. Akkaşoğlu, S. Çalışkan · 2022 · Folia Morphologica

BACKGROUND: The aim of the study is to analyse the demographic and anatomical details of the Huschke’s foramen (HF) which have not been previously studied and to present a new clinical perspective. MATERIALS AND METHODS: Multidetector computed tomography (MDCT) images of 495 patients were retrospectively evaluated. Presence of a HF, its’ size, relations to side, age and gender were noted for every patient. Size of the foramen was measured in the axial plane, as well as on the reconstructed coronal and sagittal planes. RESULTS: Of the 495 patients 99 (20%) had HF. There was no significant diffe

View details →DOI: 10.5603/fm.a2021.0056
Negative / Null Result ReportOpen accessScience

Proximate, Electrolyte and Biochemical Profile of Rabbits Fed with Tridax procumbens Residue Meal in Replacement of Vitamins and Minerals in Lapai Niger state Nigeria

I. Yahaya, Y. Ndatsu, A. Yunusa et al. · 2023 · Journal of Applied Sciences and Environmental Management

Proximate, electrolyte and biochemical profile of rabbits fed with Tridax residue meal replacing Vitamin and Mineral were evaluated in Lapai, Niger State, Nigeria using standard techniques. The dietary treatments evaluated were 20%, 40%, 60%, 80% and 0% inclusion level of Tridax. The results obtained did not follow any pattern except Urea, Globulin and Creatinine which had significant (P<0.05) decrease in the serum biochemical profile. The highest value for crude fat was seen in feed3 with value of 11.33±0.30 and the lowest was recorded in the control feed with value of 10.38±0.21. There was n

View details →DOI: 10.4314/jasem.v27i2.24
Negative / Null Result ReportOpen accessPsychology

Nogo stimuli do not receive more attentional suppression or response inhibition than neutral stimuli: evidence from the N2pc, PD and N2 components in a spatial cueing paradigm

Caroline eBarras, Dirk eKerzel · 2016 · Frontiers in Psychology

It has been claimed that stimuli sharing the color of the nogo-target are suppressed because of the strong incentive to not process the nogo-target, but we failed to replicate this finding. Participants searched for a color singleton in the target display and indicated its shape when it was in the go color. If the color singleton in the target display was in the nogo color, they had to withhold the response. The target display was preceded by a cue display that also contained a color singleton (the cue). The cue was either in the color of the go or nogo target, or it was in an unrelated, neutr

View details →DOI: 10.3389/fpsyg.2016.00630
Negative / Null Result ReportOpen accessEducation (General)

Challenging the notion of a general disfluency effect: the moderating effect of element-interactivity on perceptual disfluency

Maik Beege, Maik Beege, Christoph Mengelkamp et al. · 2026 · Frontiers in Education

IntroductionThe disfluency effect proposes that deliberately introducing challenges or difficulties into the learning process can be advantageous. Particularly, perceptual disfluency (e.g., harder to read fonts) might affect learning positively. However, an ongoing debate persists regardxing the robustness of this effect, as some studies have failed to replicate it or have uncovered opposing outcomes.MethodsTo investigate potential moderators of the disfluency effect, two experiments were conducted using different types of instructional materials (instructional texts: N1 = 76; concept maps: N2

View details →DOI: 10.3389/feduc.2025.1731080