Does Antibiotic Resistance Evolve in Hospitals?
Anna Seigal; Portia Mira; Bernd Sturmfels; Miriam Barlow · 2016 · arXiv
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“A graphical model analysis shows no association between resistance and patient information other than time of arrival.”
Abstract (excerpt)
Nosocomial outbreaks of bacteria are well-documented. Based on these incidents, and the heavy usage of antibiotics in hospitals, it has been assumed that antibiotic resistance evolves in hospital environments. To test this assumption, we studied resistance phenotypes of bacteria collected from patient isolates at a community hospital over a 2.5-year period. A graphical model analysis shows no association between resistance and patient information other than time of arrival. This allows us to focus on time course data. We introduce a Hospital Transmission Model, based on negative binomial delay
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Metadata source: arXiv