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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21346 results · page 553 of 712

Negative / Null Result ReportMedicine

High-frequency Ultrasound Evaluation of Midline Crossing-over Vessel: Correlation with Perfusion of Deep Inferior Epigastric Perforator Flap.

Lee SJ, Han HH, Eom JS et al. · 2026 · Plastic and reconstructive surgery

Background The deep inferior epigastric perforator (DIEP) flap is widely used in autologous breast reconstruction, with its success heavily reliant on the vascular anatomy, particularly midline crossing-over vessels that facilitate…

View details →DOI: 10.1097/prs.0000000000012864
Negative / Null Result ReportMedicine

Investigating the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Executive Errors Scale in Adults With Schizophrenia Spectrum Disorders.

Raudeberg R, Iverson GL · 2026 · Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Objective The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a brief neuropsychological screening battery that measures aspects of attention, immediate and delayed memory, and verbal and…

View details →DOI: 10.1093/arclin/acaf104
Negative / Null Result ReportMedicine

Stricture dynamics and prognosis during biologic therapy in ileal Crohn's disease: a real-world cohort.

Takenaka K, Kawamoto A, Hibiya S et al. · 2026 · Inflammatory bowel diseases

Background and aims Clinicians need data on the responsiveness of ileal strictures of Crohn's disease (CD) to biologic therapy, yet most trials prioritize mucosal healing. We quantified short‑term changes in ileal strictures under biologic…

View details →DOI: 10.1093/ibd/izag012
Negative / Null Result ReportMedicine

The association between hair cortisol levels, Epstein-Barr virus infections and chronic fatigue in adolescents.

Kongsnes BEB, Asprusten TT, Wyller VBB et al. · 2026 · Stress (Amsterdam, Netherlands)

Chronic fatigue after Epstein-Barr virus (EBV) infection is a significant health problem among adolescents, yet its underlying mechanisms remain unclear. This study investigated whether preinfection hair cortisol levels predict chronic…

View details →DOI: 10.1080/10253890.2026.2638303
Negative / Null Result ReportMedicine

Prospective evaluation of recombinant Herpes zoster vaccine in SSc: immunogenicity, safety and disease outcomes.

Luppino-Assad AP, Mello RP, Medeiros-Ribeiro AC et al. · 2026 · Rheumatology (Oxford, England)

Objectives To evaluate humoral immune response to recombinant zoster vaccine (RZV) in immunosuppressed patients with SSc compared with healthy controls, to identify factors influencing vaccine response and to assess RZV safety and impact…

View details →DOI: 10.1093/rheumatology/keag294
Negative / Null Result ReportMedicine

The effect of chronic disease management on engagement in healthy aging and life satisfaction in adults with diabetes.

Kıraç FÇ, Özen MY, Kıraç R et al. · 2026 · Geriatric nursing (New York, N.Y.)

Objectives This study aims to examine the effect of self-efficacy in chronic disease management on engagement in healthy aging and life satisfaction in individuals with diabetes. Methods This cross-sectional, quantitative study utilized…

View details →DOI: 10.1016/j.gerinurse.2026.103939
Negative / Null Result ReportMedicine

Correlation between lymphocyte counts and PD-L1 immune-related adverse events.

Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…

View details →DOI: 10.1177/10781552251415528
Negative / Null Result ReportOpen accessMedicine

Effect of Structured Training on ICU Nurses' Knowledge-Based Competence in Ventilator-Associated Pneumonia Prevention in a Resource-Limited Setting: An Explanatory Sequential Mixed-Methods Study.

Yakubu YH, Saani MM · 2026 · Nursing open

Aim To evaluate the effect of a structured training intervention on ICU nurses' knowledge-based competence in VAP prevention in a resource-limited setting and identify personal, environmental and organisational barriers to implementation.…

View details →DOI: 10.1002/nop2.70662
Negative / Null Result ReportOpen accessMedicine

Saddle Nose in Granulomatosis With Polyangiitis (GPA) vs. Non-GPA Patients With Septal Perforations.

Kumar N, Gomes PL, Jett S et al. · 2025 · Laryngoscope investigative otolaryngology

Objectives Saddle nose deformity (SND) can be associated with nasal septal perforation (NSP). Both SND and NSP are observed in granulomatosis with polyangiitis (GPA) patients. This study aimed to compare the prevalence and severity of SND…

View details →DOI: 10.1002/lio2.70217
Negative / Null Result ReportOpen accessMedicine

Group-Based Medical Mistrust and Logistical Factors Influencing Rheumatology Clinical Trial Enrollment: A Single-Center Cross-Sectional Survey.

Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology

Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…

View details →DOI: 10.1002/acr2.90030
Negative / Null Result Report

Similar exercise adherence and physical fitness outcomes are observed across distinct motivation profiles in older adults participating in a home-based structured exercise programme

Munns A, Feron J, Duda J et al. · 2026 · Preprint

Purpose:Motivation and self-efficacy are established predictors of engagement and persistence within structured exercise programmes; however, it remains unclear whether these psychological factors predict objective adherence metrics and…

View details →DOI: 10.31234/osf.io/gk74p_v1
Negative / Null Result ReportMedicine

Co-Occurring Substance Use and Psychiatric Disorders in Psychiatric Emergency Services: Suicidality, Substance Use, and Treatment Utilization.

Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis

Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…

View details →DOI: 10.1080/15504263.2025.2606022
Negative / Null Result ReportMedicine

Novel measures of frontal plane knee wobbling predict anterior cruciate ligament injury in Japanese female basketball players: A prospective pilot study.

Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)

Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…

View details →DOI: 10.1016/j.clinbiomech.2026.106768
Negative / Null Result ReportOpen accessMedicine

Does Bone Quality Predict Pseudarthrosis, Subsidence, or Loss of Lordosis After Anterior Cervical Discectomy and Fusion? Minimum 5-Year Cohort Study.

Kim S, Park S, Ahn DK et al. · 2026 · Global spine journal

Study DesignRetrospective cohort study.ObjectivesTo determine whether preoperative cervical bone quality assessed by computed tomography Hounsfield units (CT HU) predicts pseudarthrosis, cage subsidence, or loss of cervical lordosis after…

View details →DOI: 10.1177/21925682261424749
Negative / Null Result ReportMedicine

Chicken or the egg: The relationship between cognitive deficits and negative symptoms in first episode psychosis.

Au-Yeung C, Christophe NK, Lavigne KM et al. · 2026 · Schizophrenia research

Background Cognitive impairments and negative symptoms (NS) represent an unmet therapeutic need in psychotic disorders. Both NS and cognitive impairments, are key predictors of functioning. Both also appear during the illness prodrome,…

View details →DOI: 10.1016/j.schres.2026.02.008
Negative / Null Result Report

Social Attunement and Alcohol Use: The Role of Age and Gender

Romein C, Colyer-Patel K, Kroon E et al. · 2025 · Preprint

Background: Alcohol use typically peaks during adolescence and early adulthood, when its social reinforcement value is high, and then decreases as individuals take on more adult-like responsibilities. The present study investigates whether…

View details →DOI: 10.31234/osf.io/srk3e_v2
Negative / Null Result Report

The time course of neural activity predictive of self-initiated movement

Jeay-Bizot L, Basbug M, Maoz U et al. · 2025 · Preprint

Decades of research have shown that early ramping activity is a very reliable antecedent of self-initiated movement. However, the dominant paradigm has been to only analyze data epochs culminating in movement, which discounts how often…

View details →DOI: 10.31234/osf.io/vdbg8_v3
Negative / Null Result Report

Cannabis Use, Affect, and Emotion Regulation in Daily Life: A 3-Week Experience Sampling Method Study in People Who Smoke Cannabis Almost Daily

Donate APG, Cousijn J, Kroon E et al. · 2026 · Preprint

Background and Aims: Although many people who use cannabis report mood-enhancing effects, affective responses are thought to vary within and between individuals. This study examined the bidirectional associations between momentary affect…

View details →DOI: 10.31234/osf.io/w5fd3_v1
Negative / Null Result ReportMedicine

On how people describe paintings with mirrors.

Bertamini M, Lucia M, Diaz S et al. · 2025 · British journal of psychology (London, England : 1953)

Since antiquity humans have been fascinated by mirrors; yet, when asked to predict what is made visible in the reflection, or to interpret a scene with a mirror, observers make systematic errors. Many observers claim that a character in a…

View details →DOI: 10.1111/bjop.70042
Negative / Null Result Report

Dynamics of Torque Teno Virus DNA Load in Bronchoalveolar Lavage in COVID-19 associated Acute Respiratory Distress Syndrome

Bumberger AM, Kastner M, Rüsing L et al. · 2026 · Preprint

Background: Torque teno virus (TTV) DNA load has been proposed as a surrogate marker of the net state of immunosuppression. While plasma TTV levels have been associated with infection risk and adverse outcomes, the clinical relevance of…

View details →DOI: 10.22541/au.176770094.44860022/v1
Negative / Null Result Report

Predicting AI Anxiety: An Existential Perspective

Gobet F, Evans N, Chatfield-Jouin F et al. · 2025 · Preprint

Artificial Intelligence (AI) is transforming many aspects of daily life and improving efficiency and outcomes in various sectors, ranging from healthcare to education. However, this rapid integration also introduces significant anxiety…

View details →DOI: 10.31234/osf.io/h7zje_v1
Negative / Null Result ReportMedicine

Temperature and precipitation mismatches increase infection risk in amphibians.

Thumsová B, Martínez-Silvestre A, Pérez-Vallejo M et al. · 2025 · Current biology : CB

The thermal mismatch hypothesis (TMH), the notion that cool- and warm-adapted hosts have higher infection risk during unusually warm and cool spells, respectively, was recently proposed to explain how temperature shifts driven by climate…

View details →DOI: 10.1016/j.cub.2025.07.053