A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21742 results · page 554 of 725
Vogelsang M, Schäfer A, Ehrenreich A et al. · 2025 · Journal of Experimental Child Psychology
Studies on the development of sharing resources as one aspect of prosocial behavior have revealed that single recipient characteristics affect preschoolers’ sharing decisions. In the current study, we investigated (a) whether preschoolers…
Sookud S, Martin I, Gillan CM et al. · 2026 · Biological psychiatry. Cognitive neuroscience and neuroimaging
Background Diminished use of goal-directed (model-based) decision making is a hallmark of transdiagnostic compulsivity, promoting an overreliance on inflexible and habitual behaviors. However, the origin of this impairment remains unclear.…
Duckett W, Simons J · 2025 · Preprint
Vivid mental imagery is often assumed to relate to memory accuracy, but recent empirical findings from studies of aphantasia have found conflicting results regarding this association. The present study investigates the relationship between…
Mehari KR, Schuler KR, Haiflich A et al. · 2025 · Violence and victims
This study examined the implementation of a state law in the southern United States that required hospitals to report gunshot wounds (GSWs) to law enforcement by exploring changes in the proportion of reported GSW cases in a level 1 trauma…
Gago T, Sargisson RJ, Milfont TL · 2025 · Preprint
Despite being an important mental health consequence of climate change, climate anxiety assessment has been fragmented. Reviews of measures of climate anxiety raise concerns about content and convergent validity. We aimed to select the…
Hernández L, Williamson TM, Campbell T et al. · 2025 · The Canadian journal of cardiology
Background Cardiac rehabilitation (CR) participation improves depressive and anxious symptoms post-coronary catheterization, yet it is unclear to what extent improvements are clinically significant. This study characterized the proportion…
Bagchi A, Sengupta S, Ghosh P et al. · 2026 · Preprint
Abstract Background Rheumatoid arthritis (RA) is associated with inflammation, oxidative stress along with infiltration of immune cells (~ 90% neutrophils) into inflamed joints. Neutrophils have demonstrated the ability to…
Ivanov YV, Kartashov AV, Ivanova AI et al. · 2026 · Functional plant biology : FPB
Global climate change is accompanied by an increase in the frequency and severity of droughts, which negatively impact plant growth. One of the protective mechanisms that allows plants to withstand the negative drought effects is the…
Kalluri VS, Kalluri R · 2026 · Preprint
Tumstatin and Endostatin are endogenous extracellular matrix-derived inhibitors of angiogenesis generated from the non-collagenous domains of type IV and type XVIII collagens, respectively. Although both molecules suppress angiogenesis and…
Mbaluto CM, Martinez-Goni XS, Tripathi A et al. · 2026 · Preprint
Cereal grafting using embryonic tissues has recently become technically feasible; however, the physiological consequences of cereal grafting remain uncharacterized. We systematically evaluate photosynthetic performance and stomatal…
Segura-Chama P, Hernández VS, Zhang L · 2026 · Preprint
Adrenal chromaffin cells are key effectors of the sympathoadrenal response and play a central role in physiological adaptation to stress. While acetylcholine and pituitary ad-enylate cyclase-activating polypeptide (PACAP) are recognized…
Chan A, Freschi L, de-Pinna GFAM · 2026 · Preprint
Abstract Leaf sheaths in monocotyledons may be open or closed, yet the developmental regulation of sheath margins remains unclear in Commelinaceae, a family with closed sheaths. This study investigated the morphogenesis of leaf sheaths in…
Lanham BS, Morris RL · 2026 · Marine environmental research
The strength of biotic stressors (i.e., predation) can determine the success of shellfish reef restoration projects. In recruitment limited systems where seeding is a common restoration strategy, ensuring the survival of seeded individuals…
Turner KM, Svegborn A, Robbins TW · 2026 · Psychopharmacology
Rationale Recent research on habits and skills has produced a wave of new theories regarding the shift in control from medial to lateral regions of the dorsal striatum, and how these regions are implicated in the selected and executed of…
Aumtong S, Soongsoongnoen P, Wanwinit D · 2026 · Scientific reports
Biochar reshapes soil composition for years, yet most evidence comes from short-term, single-element laboratory incubations, leaving multi-element dynamics in tropical soils poorly resolved. We tracked 11 elements in longan-wood biochar…
Heled E, Himai Y, Papelbaum M et al. · 2026 · Journal of psychiatric research
Impaired cognitive flexibility (CF) and elevated perfectionism are well-documented in anorexia nervosa (AN), yet their contribution to symptom severity remains unclear. The current study aimed to examine whether CF predicts symptom…
Pirbornatan A, Chalmeh A, Pourjafar M et al. · 2026 · Veterinary journal (London, England : 1997)
Periparturient immunometabolic adaptations yield small, node-dependent shifts in endotoxin proxies and insulin-sensitivity indices. Direct-fed microbials (DFM) are mechanistically plausible but often produce modest metabolic readouts. Test…
Baranovskaya I, Bilous I, Alexander S et al. · 2026 · Preprint
Mineralocorticoid receptor (MR) blockade exerts sex-specific effects in hypertension and cardiovascular disease; however, its role in blood pressure regulation in spontaneously hypertensive rats (SHR) remains unclear. We assessed the…
Hura A, Green T, Kennedy C · 2026 · Archives of environmental contamination and toxicology
With increasing petroleum transport through coastal waters of the northeastern Pacific, understanding the ecological hazards of these mixtures is essential, yet the sublethal impacts on benthic filter feeders remain poorly characterized.…
Herczeg D, Horváth G, Mikó Z et al. · 2026 · Preprint
The accumulation of microplastics (MP; plastic particles 1 μm – 1 mm in diameter) in the environment is an increasing global concern. Although the physiological effects of MP on organisms, including humans, are increasingly documented,…
Hamilton WL, Moore J, Patel P et al. · 2026 · Preprint
Introduction: Invasive fungal infections (IFI) are an important cause of morbidity and mortality in haemato-oncology (haem-onc) patients with neutropenia, requiring rapid and accurate diagnosis. Gap Statement With widespread use of…
De Gregorio DA, Castro DC · 2026 · Preprint
The mu opioid receptor system has long been recognized for its role in regulating ingestive behaviors and food palatability. However, beyond their robust expression in the brain, opioid receptors are also found throughout the body,…
Wojciechowska M, Rodzeń W · 2026 · Preprint
Background: /Objectives: The present study aimed to examine the relationship between Dark Triad personality traits (narcissism, psychopathy, and machiavellianism) and conspiratorial thinking. Additionally, it sought to investigate whether…
Jorgensen E, Modahl L, Noll A et al. · 2026 · The Journal of the Acoustical Society of America
This study investigated how hearing loss and hearing aid use affect environmental sound ratings in laboratory and real-world contexts using the soundscape framework. Forty-four participants (17 normal hearing, 14 with unaided hearing loss,…
Parrish BP, McCool BA · 2026 · Neuropharmacology
Acute ethanol modulates an incredibly diverse number of neurotransmitter receptors and intracellular pathways. Presynaptic modulation by acute ethanol has been identified at some GABAergic synapses; but descriptions of acute ethanol…
Straszewski A, Troyer S, Boyer MI et al. · 2026 · The Journal of hand surgery
Purpose Routine practices without a clear impact on patient care merit continuous reassessment. This retrospective study evaluated the value of routine histopathologic and culture analysis in patients who underwent flexor or extensor…
Fang SH, Chiang MR, Li CY et al. · 2026 · Journal of muscle research and cell motility
Physical activity induces rapid myokine and metabolic responses in skeletal muscle, yet the immediate cellular adaptations to short-duration contractile activity remain incompletely defined. C2C12 myotubes were exposed to electrical pulse…
Wong R, Robertson R, Meylakh N et al. · 2026 · Neurophysiologie clinique = Clinical neurophysiology
Objectives Electroencephalographic (EEG) studies suggest chronic migraine (CM) is associated with increased global power, especially in somatosensory cortex. Furthermore, recent studies suggest chronic pain is associated with a reduced…
Lopes FM, Bantounas I, Sarov A et al. · 2026 · Nephron
Introduction Human fetal kidneys contain macrophages, innate immune cells postulated to enhance their development. Macrophages have also been implicated in the pathobiology of human kidney malformations and Wilms tumour. Human pluripotent…
Prins PJ, Buga A, Storoschuk K et al. · 2026 · Journal of the American Nutrition Association
Background Exogenous ketone supplementation acutely elevates circulating beta-hydroxybutyrate ( R -BHB), but the impact of chronic repeated dosing on exercise performance, cognition, mood, and cardiometabolic health remains unclear.…