Negative / Null Result ReportOpen accessMedicine
Davis AE, Su Y, Dallas R et al. · 2026 · Emerging microbes & infections
Human astroviruses are a common cause of viral gastroenteritis and are often underdiagnosed. While infections are typically mild or asymptomatic in immunocompetent hosts, astrovirus can cause prolonged and severe disease in…
View details →DOI: 10.1080/22221751.2026.2616946 Negative / Null Result ReportOpen accessMedicine
Mittal A, Malhotra K, Panwar V et al. · 2026 · Urology research & practice
Objective: This retrospective cross-sectional analytical study evaluated the clinicopathological associations of programmed death ligand 1 (PD-L1) and human epidermal growth factor receptor 2 (HER2/neu) expression in 250 patients with…
View details →DOI: 10.5152/tud.2026.25061 Negative / Null Result Report
Bahta H, Kahsay A, Mewcha G · 2026 · Preprint
This study aims to assess beekeeper’s perceptions of honeybee colony behavior, climate related challenges and hive productivity in Tigray. The research design was used a mixed-approach method with multi-stage sampling techniques to select…
View details →DOI: 10.22541/authorea.15004610/v1 Negative / Null Result ReportOpen accessMedicine
Qiao X, Wang Y, Tian Z et al. · 2026 · Frontiers in psychiatry
Aim To explore the symptom distress and quality of life status of patients with Chronic Kidney Disease (CKD) Stage 5 undergoing hemodialysis in China, and their correlation. Methods The Dialysis Symptom Index (DSI) and the Kidney Disease…
View details →DOI: 10.3389/fpsyt.2026.1733502 Negative / Null Result ReportOpen accessMedicine
Özen GY, Özen AK, Bilge NH · 2026 · Diagnostics (Basel, Switzerland)
Background: The anatomical position of the hyoid bone and the morphological characteristics of the soft palate play a key role in upper airway patency, craniofacial balance, and the coordination of functional structures. These features may…
View details →DOI: 10.3390/diagnostics16060947 Negative / Null Result ReportMedicine
Clarke G, Shuweihdi F, Relton SD et al. · 2026 · The British journal of general practice : the journal of the Royal College of General Practitioners
Background Primary palliative care is symptom support and care for people with life-limiting illnesses incorporated within standard primary care. Early identification of needs is best practice. There is limited research concerning…
View details →DOI: 10.3399/bjgp.2025.0602 Negative / Null Result ReportOpen accessMedicine
Hallab A · 2026 · Thyroid research
Thyroid hormones modulate brain structures during neurogenesis and impact cognition and emotions during the lifetime. Hypothyroidism is commonly associated with lower gray matter volume. Fewer studies, however, highlighted significant…
View details →DOI: 10.1186/s13044-026-00289-4 Negative / Null Result Report
Clarke B, Sajjad A, Moodie N et al. · 2026 · Preprint
The topics and questions that social and personality psychologists study attract a great deal of public interest. The level of evidence required to make an application claim should be high, in our opinion, to avoid misapplying evidence…
View details →DOI: 10.31234/osf.io/zjkcy_v3 Negative / Null Result ReportMedicine
Ojo EO, Xie R, Ng BP et al. · 2026 · Research in gerontological nursing
Purpose The current study aimed to examine the association between cognitive function, fear of falling, and physical activity and assess the moderating effect of physical activity on the association between cognitive function and fear of…
View details →DOI: 10.3928/19404921-20260615-02 Negative / Null Result ReportMedicine
Dornelas R, Marins I, Rodrigues TS et al. · 2025 · Journal of voice : official journal of the Voice Foundation
Objective To analyze the auditory perception of Korean pop (K-pop) singers' voices to identify vocal characteristics associated with gender neutrality. Study design This is a cross-sectional observational study. Methods The inclusion…
View details →DOI: 10.1016/j.jvoice.2025.11.010 Negative / Null Result ReportOpen accessMedicine
Sugimoto K, Minami T, Nukaya T et al. · 2025 · Cancer diagnosis & prognosis
Background/aim Immune checkpoint inhibitors (ICIs) have improved survival in metastatic renal cell carcinoma (mRCC), with nivolumab (NIVO) plus ipilimumab (IPI) showing benefits in intermediate- and poor-risk patients. Despite first-line…
View details →DOI: 10.21873/cdp.10488 Negative / Null Result ReportMedicine
Matouskova L, Kralova R, Parobkova E et al. · 2026 · Andrology
Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR-371a-3p testing has not yet been implemented in routine clinical practice. Cell-free DNA…
View details →DOI: 10.1111/andr.70283 Negative / Null Result ReportOpen accessMedicine
Sakulsriprasert P, Bunprajun T, Hengsomboon N et al. · 2026 · Scientific reports
This study evaluated floor and ceiling (F/C) effects within the Tampa Scale for Kinesiophobia (TSK) and examined item-level correlations with total TSK scores and pain intensity in individuals with knee osteoarthritis (KOA). A…
View details →DOI: 10.1038/s41598-026-46580-0 Negative / Null Result Report
Park S, Kim J, You Y et al. · 2026 · Preprint
Abstract Background Bacterial vaginosis (BV) is a common gynecological condition affecting women of reproductive age, characterized by disruption of vaginal microbiota. Current probiotic interventions, including oral supplements and…
View details →DOI: 10.21203/rs.3.rs-9843108/v1 Failed Experiment ReportMedicine
Düsünen E, Tural E, Yonak AK et al. · 2026 · The National medical journal of India
Background Diabetic foot ulcers are an important problem for people with diabetes mellitus. We aimed to determine the mortality rate in patients with diabetic foot ulcers and assess the relationship between mortality, the Wagner…
View details →DOI: 10.25259/nmji_536_2024 Abandoned Hypothesis
Sommer K, Russell S, Paynter J · 2026 · Preprint
This pre-registered study examined whether autistic preschool children could learn novel words from a social robot during a shared eBook reading session, how their engagement with the robot relates to word learning, and whether their…
View details →DOI: 10.31234/osf.io/nf6mh_v2 Negative / Null Result ReportMedicine
Meade-Aguilar JA, Stovall R, Ramiro S et al. · 2026 · Joint bone spine
Objectives There are limited data on how NSAID use and dosage influence hypertension risk in axial spondyloarthritis (axSpA). We evaluated the association between NSAID use and incident hypertension in a longitudinal axSpA inception…
View details →DOI: 10.1016/j.jbspin.2026.106059 Negative / Null Result ReportOpen accessMedicine
Gonzalez DE, Dickerson BL, Hines K et al. · 2026 · Sports (Basel, Switzerland)
There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. This analysis investigated whether the dose or duration of CrM was associated with SEs.…
View details →DOI: 10.3390/sports14040137 Negative / Null Result ReportMedicine
Aljarallah S, Aldeligan SH, Almarshed A et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PURPOSE.: Restless legs syndrome (RLS) is a common but under-recognised non-motor symptom in multiple sclerosis (MS), potentially linked to central nervous system lesion distribution. This study aimed to assess the anatomical distribution…
View details →DOI: 10.1007/s10072-026-08967-9 Negative / Null Result ReportMedicine
Yıldız P, Yurtseven A, Turan C et al. · 2026 · BMC pharmacology & toxicology
Methylphenidate is widely prescribed for attention-deficit/hyperactivity disorder, and its use has increased substantially in recent years. Although generally considered safe within therapeutic ranges, supratherapeutic ingestion may result…
View details →DOI: 10.1186/s40360-026-01177-1 Negative / Null Result ReportMedicine
Haksever M, Taşdemir D · 2026 · BMC pregnancy and childbirth
To evaluate the association between maternal hemoglobin and ferritin levels and fetal cortical maturation assessed by neurosonography between 30 and 34 weeks of gestation. This prospective observational study included 187 singleton…
View details →DOI: 10.1186/s12884-026-09529-9 Negative / Null Result ReportOpen accessMedicine
Kaushik A, Jaiswal A, Priya B et al. · 2025 · Journal of family medicine and primary care
Background Breast cancer is the most common cancer in women across the world. Immune cells can detect and destroy cancer cells. However, cancer cells acquire certain immune evasion mechanisms such as PD-1+ T-cells, to combat immune…
View details →DOI: 10.4103/jfmpc.jfmpc_320_25 Negative / Null Result ReportOpen accessMedicine
Zhou X · 2026 · Translational psychiatry
Low titers of blood circulating natural anti-NMDAR1 autoantibodies were reported in ~10% of the general human population. Their potential effects on NMDAR functions in the brain, however, remain unknown. We developed a new method to more…
View details →DOI: 10.1038/s41398-026-03878-x Negative / Null Result Report
Isikoglu BD, Senler FC · 2026 · Preprint
Abstract Purpose. Insomnia is a heterogeneous symptom cluster of multiple etiologies, frequently encountered in oncology patients, and chemotherapy has been implicated as a contributing factor. We aimed to evaluate the effects of…
View details →DOI: 10.21203/rs.3.rs-9973460/v1 Negative / Null Result Report
Coban S, Yavuz S, Dogan C et al. · 2026 · Preprint
Abstract Background Emergency department overcrowding is a persistent global public health issue, often driven by non-urgent visits. Health literacy is considered a key determinant of appropriate healthcare utilization. Objective This…
View details →DOI: 10.21203/rs.3.rs-9744500/v1 Negative / Null Result ReportOpen accessMedicine
Hiroshimaya T, Iwai K, Marutani M et al. · 2026 · Scientific reports
This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. Periodontitis…
View details →DOI: 10.1038/s41598-026-40128-y Replication FailureOpen accessMedicine
Amuji DN, Iweala EEJ · 2026 · BMC cancer
BACKGROUND: Breast cancer (BC) is a major cause of cancer-related mortality among women worldwide. Genetic polymorphisms, such as those in the Mesenchymal Epithelial Transition factor (MET) proto-oncogene, may influence cancer risk and…
View details →DOI: 10.1186/s12885-026-15844-3 Replication FailureOpen accessMedicine
Liu Y, Zhong S, Zhong K et al. · 2026 · Frontiers in endocrinology
Aim To investigate the association between history of gestational diabetes mellitus (GDM) and the risk of hypertensive disorders of pregnancy in subsequent pregnancy (s-HDP). Methods A retrospective cohort of 5, 928 women with two…
View details →DOI: 10.3389/fendo.2026.1736779 Negative / Null Result ReportOpen accessMedicine
Haddad A, Zabari Parnis E, Stein N et al. · 2026 · Vaccines
Background/Objective : The emergence of the COVID-19 pandemic has raised significant concerns regarding its impact on immune-mediated diseases, particularly with respect to disease induction and exacerbation. We aimed to investigate the…
View details →DOI: 10.3390/vaccines14040289 Negative / Null Result ReportMedicine
Wu Z, He S, Zhu F et al. · 2026 · Frontiers in endocrinology
Objective Copper overload has been implicated in impaired β -cell function and insulin resistance through oxidative stress and inflammatory pathways. As a major lipoprotein component involved in lipid oxidation, apolipoprotein B (apoB) may…
View details →DOI: 10.3389/fendo.2026.1764209 