e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21346 results · page 549 of 712

Negative / Null Result ReportMedicine

Effects of Time of Arrival on Trauma Patient Outcomes.

LaRosa SK, Stone XA, Fenninger AA et al. · 2024 · The American surgeon

Background Arriving during "off hours" to the hospital can put patients at greater risk of complications or mortality given lesser staff. Our goal was to investigate this in trauma patients with an Injury Severity Score (ISS) of >15. We…

View details →DOI: 10.1177/00031348241248694
Negative / Null Result ReportMedicine

Motor and Cognitive Sequence Tasks Exhibit Different Ramping Patterns in Parietal and Prefrontal Cortices.

Doyle H, Yewbrey R, Kornysheva K et al. · 2025 · Journal of cognitive neuroscience

Humans complete different types of sequences as a part of everyday life. These sequences can be divided into two important categories: those that are abstract, in which the steps unfold according to a rule at super-second to minute time…

View details →DOI: 10.1162/jocn_a_02349
Negative / Null Result ReportMedicine

Climatic resilience: Marine heatwaves do not influence the variations of green crab (Carcinus maenas) megalopae supply patterns to a Western Iberian estuary.

Monteiro M, Azeiteiro UM, Queiroga H · 2024 · Marine environmental research

Extreme climatic events like marine heatwaves (MHWs) are becoming more frequent, intense, and longer lasting all around the world. The consequences of these anomalously warm periods are devastating for marine ecosystems. Still, little is…

View details →DOI: 10.1016/j.marenvres.2024.106567
Negative / Null Result ReportOpen accessMedicine

Flexible Goal Adjustment Predicts Well-Being Before and After Retirement.

Viegas LM, Bermeitinger C, Greve W · 2026 · Journal of aging research

Background and objectives Retirement represents a critical life change and is accompanied by the blocking of professional goals. We assume that the individual capability to adapt goals to changed conditions has a palliative effect on…

View details →DOI: 10.1155/jare/2950011
Negative / Null Result ReportOpen accessMedicine

Neither the number of feature dimensions nor their task relevance necessarily affect interocular grouping in binocular rivalry.

Pedziwiatr MA, Derda M, Bator W et al. · 2026 · Attention, perception & psychophysics

When one eye views half of stimulus A and half of stimulus B, and the other eye views the respective other halves, perception fluctuates. Among percepts reflecting monocular inputs (indicating typical binocular rivalry), percepts of…

View details →DOI: 10.3758/s13414-026-03265-0
Negative / Null Result ReportMedicine

Is employment status associated with baseline symptoms, engagement, and outcomes in naturalistic psychotherapy? Evaluation in a large community mental health agency.

Jiwani Z, Xie Q, Curtin JJ et al. · 2025 · Psychotherapy (Chicago, Ill.)

Employment status, an essential socioeconomic factor, may be an important driver of disparities in mental health and access to treatment. However, prior research has been inconclusive and utilized broad employment categories. The present…

View details →DOI: 10.1037/pst0000597
Negative / Null Result ReportOpen accessMedicine

Social isolation during adolescence alters novel object recognition memory, brain and gut gene expression, and microbiota composition in a sex-specific manner.

Ahmad R, Zobel G, Hannaford R et al. · 2026 · Brain, behavior, & immunity - health

Adolescent social isolation is a known risk factor for anxiety and depression related disorders, yet its effects on brain-gut communication and potential sex differences remain unclear. We hypothesised that isolation would heighten…

View details →DOI: 10.1016/j.bbih.2026.101284
Negative / Null Result ReportMedicine

Diverse social environments and 10-year all-cause mortality in a cohort of historically excluded racial/ethnic older adults: A latent class analysis of social integration.

Flores M, Boyd SM, O'Neill RM et al. · 2025 · Annals of epidemiology

Purpose The association between social integration and mortality in older adults from historically excluded groups may not align with the patterns observed in predominately white samples. We modeled latent groups of social integration and…

View details →DOI: 10.1016/j.annepidem.2025.08.037
Negative / Null Result ReportOpen accessMedicine

Crude protein concentration in feedlot cattle growth performance, carcass merit, and nitrogen status of long-fed feedlot steers in response to dietary protein concentrations: a comparison of industry-average and reduced protein diets.

Pittaluga AM, Relling AE · 2026 · Translational animal science

Angus × SimAngus-crossbred steers ( n = 93; body weight [BW] = 342 ± 29 kg) were used in a randomized complete block design to examine the effect of feeding finishing diets with crude protein (CP) contents similar or below industry…

View details →DOI: 10.1093/tas/txag037
Negative / Null Result ReportMedicine

Dual-Energy X-Ray Absorptiometry Does Not Confirm Validity of the Craig's Test.

Clark KA, Nielsen S, Heywood T et al. · 2024 · Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

The Craig's test is a clinical assessment used to quantify femoral version. The validity of the Craig's test has been called into question due to instances where the test exhibits relatively poor correlation with three-dimensional imaging.…

View details →DOI: 10.1016/j.jocd.2024.101466
Negative / Null Result ReportOpen accessMedicine

Does the number of pages received per hour affect resident productivity?

Mangino A, Stenson BA, Leventhal EL et al. · 2023 · Journal of the American College of Emergency Physicians open

Background Workflow interruptions are common for emergency physicians and are shown to have downstream consequences such as patient dissatisfaction, delay in clinical response, and increase in medical error. However, the impact of passive…

View details →DOI: 10.1002/emp2.13071
Negative / Null Result ReportOpen accessMedicine

Association of LR treatment response category with outcome of patients with hepatocellular carcinoma on explant pathology.

Khurana A, Chai N, Gibson A et al. · 2025 · Abdominal radiology (New York)

Objectives Liver transplant (LT) is an effective treatment for hepatocellular carcinoma (HCC) in appropriately selected patients. Locoregional therapy (LRT) is often performed to extend a patient's eligibility for LT. Imaging has a modest…

View details →DOI: 10.1007/s00261-025-04811-4
Negative / Null Result ReportMedicine

Do hyperparasitoids disrupt the biological control of Pseudococcus longispinus in persimmon?

Plata Á, Gómez-Martínez MA, Beitia FJ et al. · 2023 · Biological Control.

The long-tailed mealybug, Pseudococcus longispinus, represents a threat for several crops worldwide and has become the main pest of Mediterranean persimmon. Parasitoids are the primary natural enemies of P. longispinus, but their efficacy…

View details →DOI: 10.1016/j.biocontrol.2023.105310
Negative / Null Result ReportMedicine

Neonatal hyperoxia exposure does not exacerbate hypertension programmed by maternal obesity.

do Carmo JM, Hall JE, Dai X et al. · 2026 · American journal of physiology. Regulatory, integrative and comparative physiology

Maternal obesity increases the risk of preterm delivery and rapid transition of offspring from a hypoxemic environment to a normal or elevated oxygen environment, especially if the baby receives oxygen therapy. Maternal obesity may also…

View details →DOI: 10.1152/ajpregu.00221.2025
Negative / Null Result ReportOpen accessMedicine

Duration and mode of delivery: Does maternal sleep matter?

Parttimaa H, Paavonen EJ, Perasto L et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Objective Poor sleep quality in late pregnancy has been identified as a risk factor for operative deliveries. In this study, we investigated the associations between maternal sleep throughout pregnancy and its impact on both the duration…

View details →DOI: 10.1002/ijgo.70673
Negative / Null Result ReportMedicine

HeartWare Left Ventricular Assist Device Exercise Hemodynamics With Speed Adjustment Based on Left Ventricular Filling Pressures.

Ali O, Arnold AC, Cysyk J et al. · 2024 · ASAIO journal (American Society for Artificial Internal Organs : 1992)

Functional capacity remains limited in heart failure patients with left ventricular assist devices (LVADs) due to fixed pump speed and inability to offload the left ventricle adequately. We hypothesized that manually adjusting LVAD speed…

View details →DOI: 10.1097/mat.0000000000002096
Negative / Null Result ReportOpen accessMedicine

A family history of suicide in bipolar disorders: powerful, powerless

Sagué Vilavella M, Fico G, Anmella G et al. · 2023 · European psychiatry : the journal of the Association of European Psychiatrists

Introduction When completing the medical record of a patient with bipolar disoder (BD), hardly anything is more impacting than a family history of completed suicide (FHS). In fact, FHS is a main risk factor for personal suicide attempts…

Negative / Null Result ReportMedicine

Distress tolerance, coping motives, and alcohol craving and consumption: Two experiments testing momentary responses to a mood induction.

Augur IF, Wolkowicz NR, Ham LS · 2023 · Drug and alcohol dependence

Background The current studies examined the relationship between state and trait distress tolerance (DT), drinking-related variables (alcohol craving and consumption), and the moderating role of drinking to cope with negative affect (i.e.,…

View details →DOI: 10.1016/j.drugalcdep.2023.111034
Negative / Null Result ReportOpen accessMedicine

The Role of Screentime and Family Resiliency in Overweight/Obesity in Children and Children with Developmental Disabilities Before and During COVID-19.

Mudnal PS, Chuang E, Lindly OJ et al. · 2025 · Children (Basel, Switzerland)

Background/objectives This study examines factors associated with child overweight/obesity (OW/OB), pre-COVID-19 and during the COVID-19 pandemic, among all U.S. children aged 10-17 years, with or without developmental disabilities (DD)…

View details →DOI: 10.3390/children13010066
Negative / Null Result ReportOpen accessMedicine

Age-dependent increase in peripheral neuropeptide Y with no cross-sectional link to depression.

Dahlaki M, Alam MDZ, Nyholm Nielsen M et al. · 2026 · Acta neuropsychiatrica

Background Neuropeptide Y (NPY) has been implicated in stress resilience and depression, yet findings on circulating levels in major depressive disorder (MDD) remain inconsistent, possibly due to confounders such as age, sex, and body mass…

View details →DOI: 10.1017/neu.2026.10084
Negative / Null Result ReportMedicine

The impact of co-occurring mental health problems on referral to and initiation of treatment among youth under probation supervision: Findings from a cluster randomized trial.

Stanley JN, DeLucca SC, Perron L et al. · 2024 · Journal of substance use and addiction treatment

Introduction Many youth under community supervision have substance use and co-occurring mental health issues. Yet, access to treatment is limited, and many programs cannot address co-occurring disorders. This study examines how…

View details →DOI: 10.1016/j.josat.2023.209279
Negative / Null Result ReportOpen accessMedicine

The impact of cognitive behavioral therapy for insomnia on cognitive performance and amyloid beta in older adults: A randomized controlled trial.

Siengsukon CF, Hand LK, Nelson E et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association

Introduction Insomnia is associated with increased risk for Alzheimer's disease (AD). It is unknown how cognitive behavioral therapy for insomnia (CBT-I) impacts two hallmarks of AD progression, cognitive performance and beta-amyloid (Aβ)…

View details →DOI: 10.1002/alz.71591
Negative / Null Result ReportMedicine

Posttraumatic growth and health-related quality of life in cancer survivors: Does fatigue moderate the link?

Onyedibe MC, Blickle P, Schmidt ME et al. · 2024 · Stress and health : journal of the International Society for the Investigation of Stress

Interest in post-traumatic growth (PTG) as a predictor of health-related quality of life (HRQoL) is currently gaining attention. However, current evidence is still inconclusive on the nature of this relationship. The first objective of…

View details →DOI: 10.1002/smi.3299
Negative / Null Result ReportOpen accessMedicine

Exploring the impact of virtual reality anatomy training on preparing biomedical illustrators for drawing anatomical structures.

Cheung HCK, Zhong LS, Wall SL et al. · 2026 · Anatomical sciences education

Three-dimensional visualization technologies (3DVTs) in anatomy education are popular as they offer a cost-effective and accessible alternative to cadaveric specimens. However, the literature presents conflicting results regarding the…

View details →DOI: 10.1002/ase.70150