Negative / Null Result ReportOpen accessAgriculture
S.H. Hoseinifar email ; A.R. Mirvaghefi; B. Mojazi Amiri; H.A. Khoshbavar Rostami; M. Poor Amini; K. Darvish Bastami · 2011 · Majallah-i ̒Ilmī-i Shīlāt-i Īrān
The probiotic effects of inactive yeast, Saccharomyces cerevisiae var. ellipsoideus was studied on growth performance, survival and intestinal microbiota of beluga juveniles (Huso huso). The study was done in complete randomize design that included feeding of beluga juveniles with diets supplemented with 0 (control), 1, 2 and 5% yeast (4 treatments with 3 replicates). Beluga juveniles (11.40±0.56g) were randomly allocated in 12 oval tanks at a density of 35 fish per tank and triplicate group were fed with experimental diets. At the end of the trial, growth factors (final weight, weight gain,
Negative / Null Result ReportOpen accessMedicine (General)
Lee J, Jo D, Song S et al. · 2020 · Journal of Pain Research
Jongseok Lee,1 Daehyun Jo,2 Shinmi Song,1 Dahee Park,1 Dohyeong Kim,1 Jinyoung Oh1 1Department of Anesthesiology and Pain Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Pain Center, Pohang Wooridul Hospital, Pohang-si, Gyeongsangbuk-do, Republic of KoreaCorrespondence: Jinyoung OhDepartment of Anesthesiology and Pain Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-Ro, Gangnan-Gu, Seoul, Republic of KoreaTel +82-2-2019-3600Fax +82-2-2019-4833Email sgcms3@gmail.comPurpose: Dispersion of contrast media
Negative / Null Result ReportOpen accessMedicine
Yu-Hsuan Wu, Yi-Huei Chen, Ming-Hong Chang et al. · 2018 · PLoS ONE
To evaluate the association between Parkinson's disease (PD) prognosis and the patient's onset of depression.A total of 353 patients with newly-diagnosed PD and a history of depression were enrolled. On the basis of the onset of depression before or after PD diagnosis, we divided participants into PD patients with pre- or post-diagnostic depression. Cox's regression analysis was used to detect risks between the onset of depression and outcomes (including death, accidental injury, dementia, and aspiration pneumonia). The association between the onset of depression and levodopa equivalent dosage
View details →DOI: 10.1371/journal.pone.0192050 Negative / Null Result ReportOpen accessMedicine
WANG Yibo, HAN Yingdong, XIE Tiange, WU Juan, DI Hong, ZHANG Yun, ZENG Xuejun · 2025 · Jichu yixue yu linchuang
Objective To characterize the clinical features of the group of gout patients to facilitate earlier identification, and optimize the diagnosis and treatment of the condition. Methods The retrospective study analyzed 24 gout patients with shoulder joint(s) involved and consulted by physicians of Peking Union Medical College Hospital from March 2021 to April 2025, while 70 outpatient gout patients matched by clinical course duration and sex were enrolled as control group. Clinical data including medical history, laboratory tests, therapeutic interventions. Prognosis was systematically collected
View details →DOI: 10.16352/j.issn.1001-6325.2025.11.1485 Negative / Null Result ReportOpen accessSurgery
Leonardo de Castro Durães, Eliana Ferreira Ribeiro Durães, Pedro Felipe Silva de Freitas et al. · 2013 · Acta Cirúrgica Brasileira
PURPOSE: To evaluate the feasibility and safety of a new technique for laparoscopic segmental colectomy and primary anastomosis in the left colon of rats. METHODS: Thirty rats were randomly assigned to three groups of ten animals each. All animals underwent segmental resection of the left colon and end-to-end anastomosis. In Group I, the animals underwent laparoscopic surgery with carbon dioxide pneumoperitoneum at a pressure of 5 mmHg. In Group II, the animals underwent pneumoperitoneum with carbon dioxide at a pressure of 12 mmHg. In Group III, the control group, the animals underwent open s
Negative / Null Result ReportOpen accessInternal medicine
Tutik Kusmiati, Ni Made Mertaniasih, Johanes Nugroho Eko Putranto et al. · 2022 · Acta Medica Indonesiana
Background: Drug-resistant tuberculosis (DR-TB) is a global health concern. QTc prolongation is a serious adverse effect in DR-TB patients receiving a shorter regimen. This study aimed to evaluate the correlation of moxifloxacin concentration, CRP, and inflammatory cytokines with QTc interval in DR-TB patients treated with a shorter regimen. Methods: This study was performed in 2 groups of rifampicin-resistant (RR-TB) patients receiving shorter regimens. Correlation for all variables was analyzed. Results: CRP, IL-1β, and QTc baseline showed significant differences between 45 RR-TB patients on
Negative / Null Result ReportOpen accessAnimal culture
A. Idris, E. Moors, C. Budnick et al. · 2011 · Animal
The relationship among parasitological parameters, abomasal size and body size measurements was investigated in lambs following an experimental infection with Haemonchus contortus. In total, 100 lambs from five different genotypes (German Merino (GM), Texel × GM, Suffolk × GM, German Blackhead Mutton × GM and Ile de France × GM) were experimentally infected with 5000 infective third stage larvae of H. contortus at the time of weaning at 12 weeks of age. Four and six weeks after infection, individual faecal samples were collected for estimation of faecal egg counts (FECs). Furthermore, wither h
View details →DOI: 10.1017/s1751731111000292 Negative / Null Result ReportOpen accessMedicine (General)
Omer Atis, Semsettin Sahin, Koksal Ceyhan et al. · 2019 · Eurasian Journal of Medicine
Abstract Objective: Coronary artery disease (CAD) is a multifactorial disease that is caused by various genetics and environmental factors. Genetically, predisposition is an important component for CAD. The candidate apolipoprotein E (apoE) gene is the most studied one. ApoE is composed of e2, e3, e4 alleles and E2/2, E2/3, E2/4, E3/3, E3/4, E4/4 genotypes. In this study, the relationship between CAD and apoE polymorphism and apoE level has been studied in Tokat region. Materials and Methods: The study population is composed of 100 CAD patients diagnosed by coronary angiography and 100 control
View details →DOI: 10.5152/eurasianjmed.2015.25 Negative / Null Result ReportOpen accessDentistry
Gökay Üstdal, Ayça Üstdal Güney, Eyüp Burak Küçük · 2024 · Current Research in Dental Sciences
Objective: To evaluate the shear bond strength (SBS) and the adhesive remnant index (ARI) of different traditional orthodontic adhesive systems and newly developed pre-coated adhesive systems.Methods: A total of 50 human maxillary premolars were bonded with Clarity advanced ceramic brackets using APC™ Flash-Free, APC™ PLUS, Transbond™ XT Light Cure, Opal® Bond™MV and, Blugloo™ adhesives. All samples underwent thermo-cycling. The SBS was determined using a testometric machine. A stereomicroscope was used to evaluate the adhesive remnant on debonded enamel surface. Differences among the adhesive
View details →DOI: 10.17567/currresdentsci.1555935 Negative / Null Result ReportOpen accessSpecial aspects of education
Richard Tsan-Jui Cheng · 2016 · International Review of Research in Open and Distributed Learning
Scores of studies have established that when learning online, students must be equipped with different sets of strategies and skills than in a physical classroom setting (Anderson, 2003; Broadbent & Poon, 2015; Coiro, 2007; Leu et al., 2007; Michinov, Brunot, Le Bohec, Juhel, & Delaval, 2011; Salmon, 2013). The present study, by virtue of exploring foreign language learners’ online reading experience, aimed to identify the reading strategies that learners would use when engaged in online reading activities in the target foreign languages. Thirty-two foreign language learners whose native langu
View details →DOI: 10.19173/irrodl.v17i6.2567 Negative / Null Result ReportOpen accessMedicine
Dilek Agircan, Ozlem Ethemoglu, Mustafa Calik et al. · 2024 · Haseki Tıp Bülteni
Aim: Previous studies have shown that the cerebrospinal fluid (CSF) protein level correlates with the number of demyelination criteria in electromyography in adult patients with Guillain-Barré syndrome (GBS), which is a potentially life-threatening postinfectious disease. We aimed to assess the association between CSF protein level, inflammatory markers, and electrophysiological values in the diagnosis of pediatric patients to act quickly in treating GBS. Methods: In this cross-sectional study, thirty-nine children with GBS were retrospectively analyzed from the medical records of patients who
View details →DOI: 10.4274/haseki.galenos.2024.9521 Negative / Null Result ReportOpen accessMedicine
Hessling, Martin, Gierke, Anna-Maria, Sicks, Ben et al. · 2022 · GMS Hygiene and Infection Control
Background: The measures implemented against the coronavirus pandemic also led to a sharp decline in influenza infections in the 2020/2021 flu season. In the meantime, however, the number of influenza infections has risen again; it is known from history that influenza viruses can also trigger severe pandemics. Therefore, we investigated the efficacy of ultraviolet radiation in the spectral range of 200–40 for inactivating influenza viruses.Materials and methods: The scientific literature was searched for published ultraviolet (UV) irradiation experiments with influenza viruses and the results
View details →DOI: 10.3205/dgkh000423 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Lucia Li, Haiyue Wu, Yibo Chen et al. · 2025 · Cancer Reports
ABSTRACT Background and Aims Human papillomavirus (HPV) vaccines have been available in China for only 8 years, and routine HPV testing is not recommended prior to vaccination. Therefore, evaluation of HPV vaccine effectiveness and the impact of pre‐vaccination HPV infection status on vaccine protective effect in Chinese women is warranted. Methods From June 2022 to June 2023, women aged 18 to 50 years without a history of cervical or uterine excision were recruited from three medical institutions. Baseline characteristics were compared between vaccinated and unvaccinated participants, with in
View details →DOI: 10.1002/cnr2.70294 Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Jeremy C Heard, Yunsoo A Lee, Nicholas D D'Antonio et al. · 2024 · Journal of Craniovertebral Junction and Spine
Objectives: To evaluate the (1) 90-day surgical outcomes and (2) 1-year revision rate of robotic versus nonrobotic lumbar fusion surgery. Methods: Patients >18 years of age who underwent primary lumbar fusion surgery at our institution were identified and propensity-matched in a 1:1 fashion based on robotic assistance during surgery. Patient demographics, surgical characteristics, and surgical outcomes, including 90-day surgical complications and 1-year revisions, were collected. Multivariable regression analysis was performed. Significance was set to P < 0.05. Results: Four hundred and fiftee
View details →DOI: 10.4103/jcvjs.jcvjs_145_23 Negative / Null Result ReportOpen accessMedicine
J Neves, P J Santos, I Azevedo et al. · 1999 · Acta Médica Portuguesa
Labour is very important in breech presentation and it is associated to significant morbidity and mortality enhancement in recent years. The authors made a retrospective study of breech presentation and labour with this kind of fetal presentation, in Santa Maria Hospital in 1993 and analysed the following data: maternal age, parity, gestational age, the mode of delivery, the fetal weight, the maternal and fetal morbidity and mortality. The authors also reviewed the Literature on the incidence, the most frequent complications and the management in labour to compare with the results of the study
View details →DOI: 10.20344/amp.2145 Negative / Null Result ReportOpen accessMedicine
Leela McKinnon, David R Samson, Charles L Nunn et al. · 2022 · PLoS ONE
Sleep duration, quality, and rest-activity pattern-a measure for inferring circadian rhythm-are influenced by multiple factors including access to electricity. Recent findings suggest that the safety and comfort afforded by technology may improve sleep but negatively impact rest-activity stability. According to the circadian entrainment hypothesis, increased access to electric lighting should lead to weaker and less uniform circadian rhythms, measured by stability of rest-activity patterns. Here, we investigate sleep in a Maya community in Guatemala who are in a transitional stage of industria
View details →DOI: 10.1371/journal.pone.0277416 Negative / Null Result ReportOpen accessMicrobiology
Wang Linlin, Song Tingting, Du Yuejiao et al. · 2024 · BIO Web of Conferences
In order to find out the change rule of SPAD value in lettuce leaves and the rapid, non-destructive and more accurate detection method of chlorophyll content in lettuce leaves under intercropping mode, the effect of intercropping on SPAD value in lettuce leaves was studied and the correlation model between chlorophyll content and SPAD value was established. The results show that the SPAD value of lettuce leaves increases at first and then decreases slowly with the development of the days of aerosol culture, and intercropping has obvious advantage in the middle and late stages of aerosol cultur
View details →DOI: 10.1051/bioconf/202411103003 Negative / Null Result ReportOpen accessMedicine
Philipp Fuelkell, Soenke Langner, Nele Friedrich et al. · 2018 · PLoS ONE
OBJECTIVES:To investigate acoustic noise reduction, image quality and white matter lesion detection rates of cranial magnetic resonance imaging (MRI) scans acquired with and without sequence-based acoustic noise reduction software. MATERIAL AND METHODS:Thirty-one patients, including 18 men and 13 women, with a mean age of 58.3±14.5 years underwent cranial MRI. A fluid-attenuated inversion recovery (FLAIR) sequence was acquired with and without acoustic noise reduction using the Quiet Suite (QS) software (Siemens Healthcare). During data acquisition, peak sound pressure levels were measured wit
View details →DOI: 10.1371/journal.pone.0206196 Negative / Null Result ReportOpen accessMedicine
Mujda Nooristani, Maxime Maheu, Marie-Soleil Houde et al. · 2019 · PLoS ONE
Noisy galvanic vestibular stimulation (nGVS) has been shown to enhance postural stability during stimulation, and the enhancing effect has been observed to persist for several hours post-stimulation. However, these effects were observed without proper control (sham condition) and the possibility of experimental bias has not been ruled out. The lasting effect of nGVS on postural stability therefore remains in doubt. We investigated the lasting effect of nGVS on postural stability using a control (sham) condition to confirm or infirm the possibility of experimental bias. 28 participants received
View details →DOI: 10.1371/journal.pone.0224619 Negative / Null Result ReportOpen accessSports medicine
Ayaka Yasuda, Shuhei Sasajima, Takehiro Kosaka et al. · 2023 · Journal of Physical Fitness and Sports Medicine
The purpose of this study was to investigate the effects of stimulation conditions (pressing force and frequency) and subcutaneous tissue properties (thickness and hardness) on the changes in tendon blood circulation caused by acupressure. Before and after acupressure, blood circulation of the Achilles tendon was measured using red laser lights. Acupressure was applied to the Achilles tendon for 3-min under three conditions. The following four conditions (including no stimulation condition) with different combinations of pressing forces and frequencies were established: 1) 50N and 1.5Hz, 2) 25
View details →DOI: 10.7600/jpfsm.12.147 Negative / Null Result ReportOpen accessGynecology and obstetrics
Yangyang Zhang, Yang Xu, Jiao Yu et al. · 2023 · Journal of Ovarian Research
Abstract Background A premature luteinizing hormone (LH) surge refers to an endogenous LH peak that occurs before follicle maturation or human chorionic gonadotropin injection in the process of controlled ovarian hyperstimulation. The effect of premature LH surge on pregnancy outcomes in fresh embryo transfer cycles is still controversial. The aim of this study was to explore the effect of a premature LH surge without elevated progesterone levels on the cumulative pregnancy rate (CPR) and cumulative live birth rate (CLBR) of patients during a flexible GnRH antagonist protocol. Methods A total
View details →DOI: 10.1186/s13048-023-01219-w Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Jia Lu, Yang Chen, Lili Shi et al. · 2023 · BioPsychoSocial Medicine
Abstract Background In Asia, the proportion of patients with irritable bowel syndrome (IBS) with abdominal discomfort alone is significantly higher than that in western countries. The purposes of this study are to understand the cognition of abdominal pain and abdominal discomfort in Chinese patients with IBS and to compare the clinical characteristics of patients with abdominal pain alone and with abdominal discomfort alone. Methods Patients with IBS with diarrhea (IBS-D) who met the Rome III diagnostic criteria and had episodes of at least one day/week were consecutively enrolled. The cognit
View details →DOI: 10.1186/s13030-023-00286-1 Negative / Null Result ReportOpen accessGeriatrics
Hong-Jhe Chen, Hsun Ou, Ru-Yih Chen et al. · 2025 · BMC Geriatrics
Abstract Background This study investigated the relationship between sleep disturbance, obstructive sleep apnea (OSA), and osteoporosis in older adults. Methods This cross-sectional study involved 326 older adults (mean age: 83.46 years) in elder care institutions in Taiwan. The presence of osteoporosis was assessed using dual-energy X-ray absorptiometry, while sleep quality and OSA risk were evaluated using the Pittsburgh Sleep Quality Index and STOP-Bang questionnaire, respectively. Heart rate variability (HRV) was measured to assess autonomic function. Logistic regression models, adjusted f
View details →DOI: 10.1186/s12877-025-06527-y Negative / Null Result ReportOpen accessSurgery
Camila Lopes Cardoso, Osny Ferreira Júnior, Paulo S. Perri de Carvalho et al. · 2011 · Acta Cirúrgica Brasileira
PURPOSE: To evaluate two treatment modalities of dry socket in rats and to discuss the first findings of the molecular analysis in this experimental model. METHODS: 84 rats underwent a tooth extraction were divided in 4 groups: I-uninfected socket (control), II-infected socket without any treatment, III-infected socket treated with irrigation of 2% sodium iodide and 3% hydrogen peroxide solution, IV-infected socket submitted to curettage, irrigation with physiological saline solution and fulfilled with metronidazole paste as base. The groups were subdivided in postoperative sacrifice periods:
View details →DOI: 10.1590/s0102-86502011000500007 Negative / Null Result ReportOpen accessOrthopedic surgery
Min Zou, Xin Duan, Mufan Li et al. · 2023 · Journal of Orthopaedic Surgery and Research
Abstract Background Treating lateral compression type 1 (LC1) pelvic ring injuries in older patients is controversial. This study evaluated surgical treatments combined with ERAS for treating LC1 pelvic fractures in the elderly. Methods In this retrospective study, patients who underwent surgery with INFIX (supra-acetabular spinal pedicle screws, and a subcutaneous connecting rod; the experimental group) or superior pubic ramus cannulated screw (the control group) fixation of LC1 pelvic fracture from January 2019 to January 2022 were reviewed. Injury radiography and computed tomography were pe
View details →DOI: 10.1186/s13018-023-04219-0 Negative / Null Result ReportOpen accessOils, fats, and waxes
孙玉萍，刘启东，杨亚，仇长璐，黄国栋，莫泳红，胡金华 SUN Yuping, LIU Qidong, YANG Ya, QIU Changlu, HUANG Guodong, MO Yonghong, HU Jinhua · 2023 · Zhongguo youzhi
为了对中包装的大豆油棕榈油煎炸专用调和油配方的开发和煎炸稳定性相关理化指标的选择提供参考，分别以一级大豆油、分提18 ℃棕榈油（一次精炼）及同批次的二次精炼18 ℃棕榈油为煎炸油，模拟薯条在180 ℃下高温煎炸32 h，对3种油品在煎炸过程中的酸值、过氧化值、p-茴香胺值、脂肪酸组成、极性组分含量、生育酚含量等理化指标进行了检测，并对18 ℃棕榈油中的风险因子，如PAH4、苯并（a）芘、3-氯丙醇酯（3-MCPDE）、反式脂肪酸含量进行了分析。结果表明：3种油品的酸值、过氧化值在煎炸过程中变化不明显，而p-茴香胺值、脂肪酸组成、极性组分含量在煎炸过程中变化比较明显；3种油品的生育酚氧化速度总体偏差不大；分提18 ℃棕榈油、二次精炼18 ℃棕榈油中的苯并（a）芘、反式脂肪酸含量均随煎炸时间延长呈缓慢升高的趋势；二次精炼18 ℃棕榈油的3-MCPDE在未煎炸时远高于分提18 ℃棕榈油的，3-MCPDE在煎炸初期降解剧烈，最终达到平衡；分提18 ℃棕榈油与二次精炼18 ℃棕榈油在煎炸稳定性方面没有明显区别，二次精炼不仅损失了部分有益的微量营养成分（如生育酚），还伴生出新的风险因子，如增加了3-MCPDE、反式脂肪酸。综上，酸值、过氧化值不能作为评价煎炸稳定性的敏感指标，而p-茴香胺值、脂肪酸组成、极性组分含量可作为敏感指标联合应用于评价煎炸油煎炸稳定性，另外，应倡导适度加工，以降低精炼过
View details →DOI: https://doi.org/10.19902/j.cnki.zgyz.1003-7969.210791 Negative / Null Result ReportOpen accessMedicine
Hasan M. Al-Dorzi, Abdulaziz Al-Dawood, Fahad M. Al-Hameed et al. · 2022 · Scientific Reports
Abstract There are contradictory data regarding the effect of intermittent pneumatic compression (IPC) on the incidence of deep-vein thrombosis (DVT) and heart failure (HF) decompensation in critically ill patients. This study evaluated the effect of adjunctive use of IPC on the rate of incident DVT and ventilation-free days among critically ill patients with HF. In this pre-specified secondary analysis of the PREVENT trial (N = 2003), we compared the effect of adjunctive IPC added to pharmacologic thromboprophylaxis (IPC group), with pharmacologic thromboprophylaxis alone (control group) in c
View details →DOI: 10.1038/s41598-022-12336-9 Negative / Null Result ReportOpen accessOrthopedic surgery
Diego Zanolli de Solminihac MD, Emilio Wagner MD, Pablo Wagner MD et al. · 2017 · Foot & Ankle Orthopaedics
Category: Bunion Introduction/Purpose: Hallux Rigidus (HR) is characterized initially by a decrease in Hallux metatarsophalangeal joint (MTPJ) dorsiflexion, decreasing the total range of motion. To be able to study different surgical treatment options, a cadaveric model has to be developed that recreates the limited range of motion. Our objective was to develop an Hallux Rigidus cadaveric model by shortening the plantar fascia (PF). Hallux MTPJ range of motion and joint stiffness were evaluated. Methods: 8 cadaveric foot- ankle – distal tibia specimens were prepared, identifying all extensor a
View details →DOI: 10.1177/2473011417s000426 Negative / Null Result ReportOpen accessMedicine
Jae-Hong Kim, Chang-Su Na, Myoung-Rae Cho et al. · 2022 · PLoS ONE
This study aimed to provide preliminary evidence for the efficacy of invasive laser acupuncture (ILA) for chronic non-specific low back pain (CNLBP). This was a single-center, randomized, patient and assessor-blinded, placebo-controlled, parallel-arm, clinical trial with a 1:1:1 allocation ratio that included a full analysis set. Forty-five participants with CNLBP were randomly assigned to the control group (sham laser), 650 group (650 nm-wavelength ILA), or 830 group (830 nm-wavelength ILA) (n = 15/group). All participants received ILA for 10 min, followed by electroacupuncture for 10 min on
View details →DOI: 10.1371/journal.pone.0269282 Negative / Null Result ReportOpen accessTheory and practice of education
Ali Yakar, Bilal Duman · 2022 · International Journal of Contemporary Educational Research
The purpose of the present study is to determine the effects of two multi-modal representations, the use of text and graph for learning, on problem solving, academic achievement and retention when used in a process-based instruction (PBI). The study was designed as quasi-experimental study complying with pretest-posttest control group design. The study group consists of (N=30+34=64) students from the department of classroom teacher education in the Education Faculty of a university from west of Turkey in 2015-2016 academic year. The data in the study were collected through problem solving inve
View details →DOI: 10.33200/ijcer.566067 