Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts reparative function in human mesenchymal stromal cells.
Xing L; Lu B; Zhu X; Al Saeedi M; Lerman A; Eirin A; Cohen P; Lerman LO · 2026 · Inflammation and regeneration
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Mesenchymal stromal cells (MSCs) possess therapeutic potential largely reliant on intact mitochondrial function to maintain reparative function. However, obesity compromises MSC metabolism and reparative capacity. MOTS-c, a…
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Metadata source: Europe PMC · DOI 10.1186/s41232-026-00431-7