Breaking resistance in BRAF-mutant Melanoma: Novel strategies and biomarkers for optimizing targeted therapies.
Al Hindawi MA; Omran NE; Mostafa MH; Alshihabi AM; El-Gamal MI; Omar HA · 2026 · European journal of pharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
In metastatic melanoma with a BRAF V600 mutation, inhibitors of BRAF and MEK have improved survival. Resistance may be acquired through late genetic alterations that restore mitogen-activated protein kinase (MAPK) signaling. Resistance can…
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Metadata source: Europe PMC · DOI 10.1016/j.ejphar.2026.178679