A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21339 results · page 520 of 712
Takenaka K, Kawamoto A, Hibiya S et al. · 2026 · Inflammatory bowel diseases
Background and aims Clinicians need data on the responsiveness of ileal strictures of Crohn's disease (CD) to biologic therapy, yet most trials prioritize mucosal healing. We quantified short‑term changes in ileal strictures under biologic…
Kongsnes BEB, Asprusten TT, Wyller VBB et al. · 2026 · Stress (Amsterdam, Netherlands)
Chronic fatigue after Epstein-Barr virus (EBV) infection is a significant health problem among adolescents, yet its underlying mechanisms remain unclear. This study investigated whether preinfection hair cortisol levels predict chronic…
Luppino-Assad AP, Mello RP, Medeiros-Ribeiro AC et al. · 2026 · Rheumatology (Oxford, England)
Objectives To evaluate humoral immune response to recombinant zoster vaccine (RZV) in immunosuppressed patients with SSc compared with healthy controls, to identify factors influencing vaccine response and to assess RZV safety and impact…
Kıraç FÇ, Özen MY, Kıraç R et al. · 2026 · Geriatric nursing (New York, N.Y.)
Objectives This study aims to examine the effect of self-efficacy in chronic disease management on engagement in healthy aging and life satisfaction in individuals with diabetes. Methods This cross-sectional, quantitative study utilized…
Freeman D, Rosebrock L, Waite F · 2026 · Schizophrenia research
Background Initial patient perceptions of a treatment's credibility, and expectations for improvement, have been shown to predict to a small degree outcomes for common mental health disorders. This study aimed to discover: how patients…
Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…
Chernetska V, Millgram Y · 2025 · Preprint
Background: Suicidal thoughts affect approximately 10% of the population during their lifetime. In about one-third of cases, these thoughts persist, contributing to poorer health and elevated suicide risk. Emotion regulation deficits were…
Yakubu YH, Saani MM · 2026 · Nursing open
Aim To evaluate the effect of a structured training intervention on ICU nurses' knowledge-based competence in VAP prevention in a resource-limited setting and identify personal, environmental and organisational barriers to implementation.…
Kumar N, Gomes PL, Jett S et al. · 2025 · Laryngoscope investigative otolaryngology
Objectives Saddle nose deformity (SND) can be associated with nasal septal perforation (NSP). Both SND and NSP are observed in granulomatosis with polyangiitis (GPA) patients. This study aimed to compare the prevalence and severity of SND…
Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology
Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…
Munns A, Feron J, Duda J et al. · 2026 · Preprint
Purpose:Motivation and self-efficacy are established predictors of engagement and persistence within structured exercise programmes; however, it remains unclear whether these psychological factors predict objective adherence metrics and…
Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis
Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…
Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)
Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…
Hart SN, Bergamaschi TS · 2025 · Preprint
Objective To develop and validate an agent-based Large Language Model (LLM) system for extracting structured data from breast cancer synoptic pathology reports and assess the performance gap between synthetic and real-world validation.…
Chira A, de la Fuente Garcia S · 2025 · Preprint
Morality is deeply rooted in the context of relationships. Yet the influence of relational factors, such as attachment, on moral concerns remains largely unexplored. Nonetheless, recent scholarship has shed some light on the connection…
Sharpe L, Shaw J, Boyse JB et al. · 2026 · British journal of health psychology
Aims Asthma is a chronic condition characterized by episodes of breathlessness. Although common, asthma is known to be associated with higher rates of depression and anxiety, but there are few studies that have attempted to document the…
Ming X, Liu H, Yang J et al. · 2026 · Applied psychology. Health and well-being
Prior studies suggest that mindfulness interventions are viable for alleviating insomnia; however, the potential bidirectional link between mindfulness and insomnia warrants a longitudinal study. This study investigates the bidirectional…
Yanowitz T, Patel A · 2025 · Preprint
Abstract OBJECTIVE: To evaluate whether delayed cord clamping (DCC) duration predicts hyperbilirubinemia and phototherapy days among preterm infants of different gestational ages. STUDY DESIGN: In this retrospective cohort study, 2,421…
Vanhanen EJ, Lehtimäki TE, Kolho KL et al. · 2026 · Therapeutic advances in gastroenterology
Background The prognostic value of magnetic resonance imaging (MRI) in pediatric-onset primary sclerosing cholangitis (PSC) remains poorly studied. The MRI-based ANALI scores with and without gadolinium (ANALI Gd and ANALI NoGd ) have…
Pinder J, Labouliere C, Wang SB et al. · 2025 · Preprint
Objective: Safety planning interventions (SPIs) may prevent suicidal behavior among adolescents, but many adolescents in need do not receive an SPI. Self-guided digital SPIs could reach many vulnerable youth, but the quality of…
Habaguchi A, Katano S, Yano T et al. · 2026 · Circulation journal : official journal of the Japanese Circulation Society
Background Whether the components of sarcopenia provide sex-specific prognostic information in heart failure (HF) remains uncertain. Methods and results We enrolled 604 patients with HF (259 women; median age, 73 years) undergoing…
Kirkham R, Aidman E, Yücel M et al. · 2026 · Journal of affective disorders
Burnout is a prevalent and costly work-related condition characterized by four symptom dimensions: cognitive impairment, emotional impairment, mental distance and exhaustion. Although coping, coping flexibility, and cognitive flexibility…
Walker D, Staniforth CE, Thomas J et al. · 2025 · Preprint
The English Premier League claim that the introduction of the Video Assistant Referee (VAR) has led to more correct decisions. However, the psychological mechanisms of the current protocol have yet to be explored, and the current study…
McGrory CM, Fireman GD, Bottary RM et al. · 2025 · Preprint
Abstract Background . Individuals with Social Anxiety Disorder (SAD) often experience poor sleep, which may influence treatment outcomes. Although theoretical models link sleep and fear extinction mechanisms, findings are equivocal and…
Hewitt KM, Bayliss DM, McLean BA et al. · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While…
Kim S, Park S, Ahn DK et al. · 2026 · Global spine journal
Study DesignRetrospective cohort study.ObjectivesTo determine whether preoperative cervical bone quality assessed by computed tomography Hounsfield units (CT HU) predicts pseudarthrosis, cage subsidence, or loss of cervical lordosis after…
Au-Yeung C, Christophe NK, Lavigne KM et al. · 2026 · Schizophrenia research
Background Cognitive impairments and negative symptoms (NS) represent an unmet therapeutic need in psychotic disorders. Both NS and cognitive impairments, are key predictors of functioning. Both also appear during the illness prodrome,…
Ortells-Faci P, McDanal R, Zhang Y et al. · 2025 · Preprint
Objective: Adolescence is characterized by increased vulnerability to internalizing symptoms, particularly among girls. Although peer victimization and rumination have each been implicated in this vulnerability, their dynamic,…
Romein C, Colyer-Patel K, Kroon E et al. · 2025 · Preprint
Background: Alcohol use typically peaks during adolescence and early adulthood, when its social reinforcement value is high, and then decreases as individuals take on more adult-like responsibilities. The present study investigates whether…
Jeay-Bizot L, Basbug M, Maoz U et al. · 2025 · Preprint
Decades of research have shown that early ramping activity is a very reliable antecedent of self-initiated movement. However, the dominant paradigm has been to only analyze data epochs culminating in movement, which discounts how often…