Negative / Null Result ReportMedicine
Gonzalez-Nahm S, Griffith E, Maguire RL et al. · 2026 · Childhood obesity (Print)
Objective To assess the longitudinal associations between maternal diet during pregnancy and child adiposity between ages 2 and 12 years. Methods Repeated measures linear regression models with autoregressive covariance were used to assess…
View details →DOI: 10.1177/21532176261420979 Negative / Null Result ReportOpen accessMedicine
Wei C, Ng VWS, Wei Y et al. · 2025 · BMC psychiatry
AIMS: Preclinical studies have suggested potential anticancer effects of valproate, but clinical evidence is limited and inconclusive. This study aims to reexamine the relationship between valproate use and cancer incidence, using lithium…
View details →DOI: 10.1186/s12888-025-07622-5 Negative / Null Result ReportOpen accessMedicine
Winkelman JW, Levine MJ · 2026 · AACE endocrinology and diabetes
Type 2 diabetes mellitus is a highly prevalent metabolic disorder and a well-established risk factor for colorectal cancer (CRC), mediated by hyperglycemia, hyperinsulinemia, chronic inflammation, and obesity-related metabolic dysfunction.…
View details →DOI: 10.1016/j.aed.2026.02.013 Negative / Null Result ReportOpen accessMedicine
Acierno J, Tedaldi E, Ginn J et al. · 2026 · Communications psychology
Social norms have a reliable and oftentimes strong influence on individual attitudes and behaviors across environmental and other domains. This influence has been theorized to differ by cultural tightness-the extent to which people adhere…
View details →DOI: 10.1038/s44271-026-00429-4 Negative / Null Result ReportOpen accessMedicine
El Alam A, Fleifel M, Nassani BM · 2026 · Cureus
Background Meal frequency takes a large focus when people enter a weight-loss program. Objective The primary aim of this study was to compare fat percentage and muscle percentage across three self-reported meal-frequency patterns,…
View details →DOI: 10.7759/cureus.105105 Negative / Null Result Report
Bateman SP, Wright K · 2024 · Preprint
Personality is regarded as stable over time, and thus measures of personality assume that personality traits are largely unaffected by one's state. However, several studies demonstrate that personality measurements can be biased by one's…
View details →DOI: 10.31234/osf.io/hxzt6 Negative / Null Result ReportMedicine
El-Enbaby H, Hollingsworth B, Maystadt JF et al. · 2024 · Economics and human biology
The relationship between poverty and mental health is complex. Conditional cash transfers are seen as an important policy tool in reducing poverty and fostering social protection. Evidence on the impact of cash transfers on mental health…
View details →DOI: 10.1016/j.ehb.2024.101396 Negative / Null Result ReportOpen accessMedicine
Kransberg J, Sjøli Bråthen AC, Falch ES et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Grid cells in the human entorhinal cortex (EC) play a critical role in spatial navigation and memory. The EC is also one of the first regions affected by ageing and Alzheimer's disease. This pre-registered functional magnetic resonance…
View details →DOI: 10.1162/imag.a.1196 Negative / Null Result ReportOpen accessMedicine
Wenzel K, Thomas J, Carrano J et al. · 2025 · Drug and alcohol dependence reports
Substance use disorders (SUDs) including opioid use disorder (OUD) and alcohol use disorder (AUD) contribute to significant morbidity and mortality in the United States. Pharmacotherapy treatment, including extended-release naltrexone…
View details →DOI: 10.1016/j.dadr.2025.100346 Negative / Null Result ReportOpen accessMedicine
Liu X, Zhu Z, Chawes B et al. · 2026 · Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
Background Vitamin D may play a role in early lung development, yet epidemiologic evidence on its association with later asthma risk is mixed. We aimed to investigate the associations of neonatal 25-hydroxyvitamin D (25(OH)D) and vitamin…
View details →DOI: 10.1111/pai.70299 Negative / Null Result ReportOpen accessMedicine
Chatila ZK, Duggan MR, Silberberg E et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association
While a growing body of literature suggests a role for infections in Alzheimer's disease (AD), microbial contributions to AD remains a contentious topic, in part due to challenges in reconciling the positive evidence with studies reporting…
View details →DOI: 10.1002/alz.71288 Negative / Null Result ReportOpen accessMedicine
Helac A, Uchino BN · 2025 · Acta psychologica
General perceived social support is important because it is linked to significant health outcomes. Most research examining perceived social support and health behaviors has not formally modeled the influence of interdependence in a dyad.…
View details →DOI: 10.1016/j.actpsy.2025.105641 Negative / Null Result ReportMedicine
Sarfraz S, Fouad Elganainy M, Waris U et al. · 2026 · Proceedings (Baylor University. Medical Center)
Background Secondhand smoke (SHS) is a major cardiovascular risk factor, but its relationship with resting tachycardia, a marker of autonomic imbalance and adverse prognosis, remains unclear in young adults. Methods We analyzed adults aged…
View details →DOI: 10.1080/08998280.2026.2637414 Negative / Null Result ReportOpen accessMedicine
Roozenbeek J, Lasser J, Marks M et al. · 2025 · Royal Society open science
The spread of misinformation on social media continues to pose challenges. While prior research has shown some success in reducing susceptibility to misinformation at scale, how individual-level interventions impact the quality of content…
View details →DOI: 10.1098/rsos.251377 Negative / Null Result ReportOpen accessMedicine
Wei Y, Li J · 2025 · Discover oncology
Background Non-alcoholic fatty liver disease (NAFLD) has been increasingly associated with hepatocellular carcinoma (HCC) risk in observational studies, yet the causal nature of this relationship and its impact on systemic lipid metabolism…
View details →DOI: 10.1007/s12672-025-03582-0 Negative / Null Result ReportOpen accessMedicine
Zhou C, Dong X, Chen G et al. · 2025 · Nature medicine
After the global approval of atezolizumab plus bevacizumab and chemotherapy as first-line metastatic nonsquamous non-small-cell lung cancer (nsqNSCLC) treatment, the IMpower151 ( NCT04194203 ) trial was conducted in China to address…
View details →DOI: 10.1038/s41591-025-03658-y Negative / Null Result ReportMedicine
Esparragosa Vazquez I, Sanson M, Chinot OL et al. · 2024 · Neuro-oncology advances
Background Based on preclinical studies showing that IDH-mutant (IDHm) gliomas could be vulnerable to PARP inhibition we launched a multicenter phase 2 study to test the efficacy of olaparib monotherapy in this population. Methods Adults…
View details →DOI: 10.1093/noajnl/vdae078 Negative / Null Result Report
Takahara N, Nakai Y, Isayama H et al. · 2022 · Preprint
Purpose: Given the promising activity and tolerability of FOLFIRINOX as a second-line treatment for advanced biliary tract cancer (BTC), it can be an attractive first-line treatment option as well. Materials: and Methods: This is a…
View details →DOI: 10.21203/rs.3.rs-2075157/v1 Negative / Null Result ReportOpen accessMedicine
Zumla A, Rosenthal PJ, Sam-Agudu NA et al. · 2025 · The American journal of tropical medicine and hygiene
On August 14, 2024, following a regional declaration by the Africa Centres for Disease Control and Prevention, the World Health Organization declared mpox a Public Health Emergency of International Concern, marking the second such…
View details →DOI: 10.4269/ajtmh.24-0606 Negative / Null Result ReportMedicine
Yuan H, Curran JG, Keith SW et al. · 2021 · Headache
Objective To evaluate the efficacy and safety of intravenous (IV) Ibuprofen for acute treatment of migraine. Background IV nonsteroidal anti-inflammatory drugs (NSAIDs) are an alternative to oral NSAIDs, especially in patients with severe…
View details →DOI: 10.1111/head.14214 Negative / Null Result ReportMedicine
Møller P, Roursgaard M · 2024 · Mutation research. Reviews in mutation research
Humans ingest particles and fibers on daily basis. Non-digestible carbohydrates are beneficial to health and food additives are considered safe. However, titanium dioxide (E171) has been banned in the European Union because the European…
View details →DOI: 10.1016/j.mrrev.2024.108491 Negative / Null Result ReportOpen accessMedicine
Jin Q, Liu Y, Tong Q et al. · 2025 · Frontiers in nutrition
Objective To examine whether a concise, clinic-feasible Patient Inflammatory Diet Score (PIDS) relates to prevalent pancreatic cancer and cardiovascular disease (CVD) in a hospital population, and to explore associations with systemic…
View details →DOI: 10.3389/fnut.2025.1666682 Negative / Null Result ReportMedicine
Davidenko N, Day J · 2025 · Memory & cognition
Humans' ability to draw faces accurately from memory is extremely rare. One source of difficulty is the drawing process itself, which requires converting a complex, three-dimensional mental representation to a two-dimensional drawing. To…
View details →DOI: 10.3758/s13421-023-01498-0 Negative / Null Result ReportMedicine
Gaskins AJ, Newman AJ, Kawwass JF et al. · 2026 · Environmental research
Background While extreme ambient heat has been associated with several adverse pregnancy and birth outcomes little is known regarding the link between extreme ambient temperatures and human fertility. Objective To evaluate the associations…
View details →DOI: 10.1016/j.envres.2026.123783 Negative / Null Result ReportOpen accessMedicine
van Bree S, Mackenzie AS, Wimber M · 2024 · Imaging neuroscience (Cambridge, Mass.)
The application of multivariate pattern analysis (MVPA) to electroencephalography (EEG) data allows neuroscientists to track neural representations at temporally fine-grained scales. This approach has been leveraged to study the locus and…
View details →DOI: 10.1162/imag_a_00330 Negative / Null Result ReportOpen accessMedicine
Sato K, Inoue K, Yamaguchi T et al. · 2025 · JAMA network open
Importance Excess salt intake is a major modifiable risk factor for hypertension and cardiovascular disease. Personalized interventions using genetic information and digital tools, such as smartphone applications, may enhance sodium…
View details →DOI: 10.1001/jamanetworkopen.2025.37540 Negative / Null Result ReportOpen accessMedicine
Liu P, Zeng Q · 2025 · Journal of multidisciplinary healthcare
Background The causal relationship between HIV infection and insulin resistance, as well as diabetes mellitus, remains uncertain. This study explores these associations using genome-wide association study data and Mendelian randomization…
View details →DOI: 10.2147/jmdh.s546669 Negative / Null Result ReportOpen accessMedicine
Shaaban M, Ryan JT, Adediran E et al. · 2026 · F&S reports
Objective To study whether incident endometriosis diagnosis, staging, and typology are associated with concurrent elevated serum inflammatory markers interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF- α ).…
View details →DOI: 10.1016/j.xfre.2026.02.007 Negative / Null Result Report
Levy H, Naples A, Collett S et al. · 2023 · Preprint
Individuals with hoarding disorder (HD) have difficulty parting with personal possessions, which leads to the accumulation of excessive clutter. According to a proposed biphasic neurobiological model, HD is characterized by blunted central…
View details →DOI: 10.22541/au.169524727.72955633/v1 Negative / Null Result ReportOpen accessMedicine
Zebarjadi N, Kluge A, Adler E et al. · 2024 · eNeuro
The study of ideological asymmetries in empathy has consistently yielded inconclusive findings. Yet, until recently these inconsistencies relied exclusively on self-reports, which are known to be prone to biases and inaccuracies when…
View details →DOI: 10.1523/eneuro.0086-24.2024