Negative / Null Result Report
Furze ME, Rodriguez-Urquidi A, Galeano M et al. · 2026 · Preprint
As extreme heat events increase in frequency and intensity worldwide, understanding how woody perennial crops respond to higher maximum temperatures is critical. Perennials face distinct challenges, persisting across many seasons under…
View details →DOI: 10.64898/2026.06.24.734398 Negative / Null Result ReportMedicine
Thomas RM, Nayak R, Madi M et al. · 2026 · BMC oral health
Remaining Root Dentin Thickness (RRDT) after root canal instrumentation is an important parameter to be assessed with newer file systems. This study aimed to evaluate the root dentin thickness following instrumentation of primary molar…
View details →DOI: 10.1186/s12903-026-09005-y Negative / Null Result ReportMedicine
Zapata KA, McGinley JJ, Sucato DJ et al. · 2026 · Spine deformity
Purpose To evaluate the effectiveness of nighttime brace treatment in boys with adolescent idiopathic scoliosis (AIS) compared to girls according to brace adherence and curve progression. Methods Children with predominantly…
View details →DOI: 10.1007/s43390-026-01492-x Failed Experiment Report
Bleckwedel J, Nieva RE, González V et al. · 2026 · Preprint
Soybean ( Glycine max [L.] Merr.) productivity is frequently compromised by soil-borne pathogens. Macrophomina phaseolina (Mp), the causal agent of charcoal rot, can produce important soybean yield losses especially when hot and dry…
View details →DOI: 10.64898/2026.05.11.724353 Negative / Null Result ReportMedicine
Hayashi K, Yoshida M, Hayashi S et al. · 2026 · Japanese journal of ophthalmology
Purpose To compare visual function between pseudophakic eyes with enhanced monofocal intraocular lenses (IOLs) and phakic eyes with clear lenses among patients in their 50s, 60s, and 70s. Study design Prospective comparative study. Methods…
View details →DOI: 10.1007/s10384-025-01321-0 Failed Experiment ReportMedicine
Strumpf ZB, Balijepalli S, Galchenko P et al. · 2026 · Respiratory medicine
Purpose Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is essential for mediastinal staging in non-small cell lung cancer (NSCLC), yet uniform lymph node (LN) size criteria for sampling remain unvalidated.…
View details →DOI: 10.1016/j.rmed.2026.108959 Negative / Null Result ReportMedicine
Chapron L, Bellot L, Mallet Y et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To assess the diagnostic value of tomographic signs on OCT and OCT-A, particularly paracentral acute middle maculopathy (PAMM), in predicting temporal artery biopsy (TAB) positivity in suspected giant cell arteritis (GCA),…
View details →DOI: 10.1097/iae.0000000000004783 Negative / Null Result ReportMedicine
Shehu E, Arora K · 2026 · Health services research
Objective To examine whether different caregiving arrangements influence hospitalization risk and frequency among older adults with functional limitations. Study setting and design This longitudinal study used linear probability and…
View details →DOI: 10.1111/1475-6773.70130 Negative / Null Result ReportMedicine
Zhang Y, Yu W, Shen W · 2026 · Medicine
This study aimed to explore the effects of 3 immediate reconstruction methods - prosthesis implantation, latissimus dorsi flap (LDF), or their combination - on postoperative outcomes following breast cancer (BC) surgery. A retrospective,…
View details →DOI: 10.1097/md.0000000000049090 Negative / Null Result ReportMedicine
Tomalka A, Weidner S, Rode C et al. · 2026 · Experimental physiology
Eccentric muscle contractions are essential for locomotion and daily activities. Force during these contractions depends on both cross-bridge (XB) and non-cross-bridge (non-XB) elements, including titin, with contributions varying by fibre…
View details →DOI: 10.1113/ep093831 Negative / Null Result Report
Qi Z, Li W, Li Z et al. · 2026 · Preprint
Abstract Background Female genital cosmetic surgery (FGCS) has gained increasing popularity worldwide, with high reported satisfaction rates. However, dynamic postoperative changes may lead to patient anxiety and misinterpretation during…
View details →DOI: 10.21203/rs.3.rs-9212553/v1 Negative / Null Result Report
Ismaile S, Alhosban F, Shajrawi A et al. · 2026 · Preprint
Abstract Background Preparing undergraduate nurses for high-acuity practice requires educational approaches that allow safe rehearsal of complex clinical situations, yet evidence from routine programme delivery remains mixed when immersive…
View details →DOI: 10.21203/rs.3.rs-9187827/v1 Negative / Null Result ReportMedicine
Swallow C, Imamoglu M, Imamoglu AG et al. · 2025 · Urogynecology (Philadelphia, Pa.)
Importance Sacrocolpopexy is essential in the surgical management of advanced pelvic organ prolapse, and selecting the appropriate route for concomitant hysterectomy is critical. Objectives The aim of this study was to evaluate the effect…
View details →DOI: 10.1097/spv.0000000000001659 Negative / Null Result ReportOpen accessMedicine
Quan TT, Nguyen HM, Nguyen HT et al. · 2026 · Cureus
Objective This study aims to describe ductus arteriosus (DA) morphology in patients with pulmonary atresia with ventricular septal defect (PA-VSD) and to assess exploratory paired differences between echocardiography and digital…
View details →DOI: 10.7759/cureus.108765 Negative / Null Result Report
Sorjonen K, Melin B, Melin M · 2026 · Preprint
Based on statistically significant effects in cross-lagged panel network (CLPN) models, Ning and Zou concluded bidirectional prospective influences between negative self-attention and depression. However, cross-lagged effects may be…
View details →DOI: 10.31234/osf.io/4pqj7_v1 Negative / Null Result ReportOpen accessMedicine
Seber T, Uylar Seber T, Çiçek F et al. · 2026 · Journal of pain research
Purpose Fibromyalgia (FM) is a chronic pain syndrome frequently associated with neuroendocrine dysfunction and has been hypothesized to share pathophysiological mechanisms with conditions such as empty sella (ES) and intracranial…
View details →DOI: 10.2147/jpr.s609244 Negative / Null Result ReportMedicine
Goc G, Sukur YE · 2026 · Journal of minimally invasive gynecology
Study objective To compare embryo euploidy rates and reproductive outcomes among women with ovarian endometriomas who underwent ethanol sclerotherapy (EST), laparoscopic cystectomy, or expectant management prior to in vitro fertilization…
View details →DOI: 10.1016/j.jmig.2026.06.010 Negative / Null Result ReportMedicine
Koga S, Noguchi S, Kondo T · 2026 · Pediatric surgery international
Purpose Appendiceal location may affect the diagnosis and surgical management of acute appendicitis. However, pediatric-specific data remain limited. This study evaluated appendiceal location in Japanese children with acute appendicitis…
View details →DOI: 10.1007/s00383-026-06498-0 Negative / Null Result Report
Akdag A, Aktas E, Kutlu A et al. · 2026 · Preprint
Abstract Purpose: Residual fragments after retrograde intrarenal surgery (RIRS) may compromise delayed stone-free (SF) status and increase the likelihood of secondary intervention. This study evaluated the association between postoperative…
View details →DOI: 10.21203/rs.3.rs-9849277/v1 Negative / Null Result Report
Sağlam A, Kurutaş EB, Yağmur I et al. · 2026 · Preprint
Abstract Psoriasis is a chronic immune-mediated inflammatory skin disease associated with systemic inflammation and metabolic disturbances. Adipokines have been suggested as key mediators linking metabolic dysregulation and inflammatory…
View details →DOI: 10.21203/rs.3.rs-9211473/v1 Negative / Null Result ReportMedicine
Kitamura K, Fujii M, Yamate S et al. · 2026 · International orthopaedics
Purpose The role of periacetabular osteotomy (PAO) in symptomatic borderline hip dysplasia (borderline HD) remains controversial because the lateral centre-edge angle may not reflect global dysplastic morphology. We examined whether…
View details →DOI: 10.1007/s00264-026-06923-y Negative / Null Result ReportMedicine
Carkit S, Karaagac M · 2026 · Annals of surgical oncology
Background Esophageal cancer is associated with substantial morbidity and mortality worldwide and is frequently diagnosed at advanced stages, leading patients and their relatives to seek health-related information beyond traditional…
View details →DOI: 10.1245/s10434-026-19996-1 Negative / Null Result ReportMedicine
Van der Cruyssen F, Willaert R, Palla B et al. · 2026 · International journal of oral and maxillofacial surgery
Trigeminal nerve injuries severely degrade quality of life, yet comparative effectiveness evidence for existing treatments is scarce. The authors prospectively followed 153 adults with iatrogenic lingual or inferior alveolar nerve injuries…
View details →DOI: 10.1016/j.ijom.2026.06.014 Negative / Null Result ReportMedicine
Baştemur AG, Haliloğlu E, Tanaçan A et al. · 2026 · Journal of reproductive immunology
Aim This study aimed to investigate the association between the aggregate index of systemic inflammation (AISI), a novel indicator of inflammation, miscarriage, and other pregnancy complications in patients with threatened miscarriage.…
View details →DOI: 10.1016/j.jri.2026.104869 Negative / Null Result Report
Oh J, Park J, Kang D et al. · 2026 · Preprint
Background: /Objectives: Poor bone quality significantly increases the risk of mechanical complications after adult spinal deformity (ASD) surgery, including proximal junctional kyphosis (PJK) and proximal junctional failure (PJF).…
View details →DOI: 10.20944/preprints202606.1461.v1 Negative / Null Result ReportMedicine
Wayne KS, Liu H, Canales KK et al. · 2026 · Pediatric cardiology
The frontal QRS-T angle, derived from a standard 12-lead electrocardiogram (ECG), quantifies the relationship between ventricular depolarization and repolarization. Although a widened angle has been associated with myocardial disarray and…
View details →DOI: 10.1007/s00246-026-04329-6 Negative / Null Result ReportMedicine
Argon BD, Durmuş ŞV · 2026 · Cornea
Purpose To compare the accuracy and safety of 4 large language models on cornea and external disease multiple-choice questions (MCQs). Methods DeepSeek-V3.2, GPT-5.2 (via ChatGPT), Gemini 3 Pro, and Claude Opus 4.5 were tested on American…
View details →DOI: 10.1097/ico.0000000000004219 Negative / Null Result ReportMedicine
Güzel İ, Saraç H · 2026 · BMC surgery
Background The optimal timing of weight-bearing after surgical fixation of isolated lateral malleolar fractures remains debated. Although delayed mobilization is commonly practiced, early weight-bearing has been proposed as a strategy to…
View details →DOI: 10.1186/s12893-026-03836-w Negative / Null Result ReportMedicine
Kanakan A, Singh A, Kumari S et al. · 2026 · Frontiers in aging
Chronic inflammation contributes to the pathogenesis of sarcopenia in older adults. This study aimed to evaluate the correlation between inflammatory biomarkers such as C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α),…
View details →DOI: 10.3389/fragi.2026.1770257 Negative / Null Result Report
özcan FÖ, OKUDU C, Odabaş Hİ et al. · 2026 · Preprint
Abstract Purpose Chicory coffee is increasingly consumed as a caffeine-free alternative to traditional coffee; however, its acute effects during exercise remain unclear. This study aimed to compare the effects of a single serving of…
View details →DOI: 10.21203/rs.3.rs-9678223/v1