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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21733 results · page 475 of 725

Negative / Null Result ReportMedicine

Comparative evaluation of root dentin thickness following hand and rotary instrumentation of primary molar root canals using cone-beam computed tomography - an invitro study.

Thomas RM, Nayak R, Madi M et al. · 2026 · BMC oral health

Remaining Root Dentin Thickness (RRDT) after root canal instrumentation is an important parameter to be assessed with newer file systems. This study aimed to evaluate the root dentin thickness following instrumentation of primary molar…

View details →DOI: 10.1186/s12903-026-09005-y
Failed Experiment Report

Compatibility and Multi-Season Field Evaluation of Trichoderma koningiopsis Integrated with Fungicides for Soybean Charcoal Rot Management

Bleckwedel J, Nieva RE, González V et al. · 2026 · Preprint

Soybean ( Glycine max [L.] Merr.) productivity is frequently compromised by soil-borne pathogens. Macrophomina phaseolina (Mp), the causal agent of charcoal rot, can produce important soybean yield losses especially when hot and dry…

View details →DOI: 10.64898/2026.05.11.724353
Negative / Null Result ReportMedicine

Age-stratified comparison of visual function between eyes with an enhanced monofocal intraocular lens and phakic eyes.

Hayashi K, Yoshida M, Hayashi S et al. · 2026 · Japanese journal of ophthalmology

Purpose To compare visual function between pseudophakic eyes with enhanced monofocal intraocular lenses (IOLs) and phakic eyes with clear lenses among patients in their 50s, 60s, and 70s. Study design Prospective comparative study. Methods…

View details →DOI: 10.1007/s10384-025-01321-0
Negative / Null Result ReportMedicine

Comparative study of prosthesis implantation, latissimus dorsi flap, and combined reconstruction immediately after breast cancer surgery: A retrospective, single-center, observational cohort study.

Zhang Y, Yu W, Shen W · 2026 · Medicine

This study aimed to explore the effects of 3 immediate reconstruction methods - prosthesis implantation, latissimus dorsi flap (LDF), or their combination - on postoperative outcomes following breast cancer (BC) surgery. A retrospective,…

View details →DOI: 10.1097/md.0000000000049090
Negative / Null Result Report

Immersive Virtual Reality in Undergraduate Critical Care Nursing Education: A Pragmatic Three-Cohort Quasi-Experimental Evaluation of Perceived Simulation Effectiveness and Clinical Learning Needs

Ismaile S, Alhosban F, Shajrawi A et al. · 2026 · Preprint

Abstract Background Preparing undergraduate nurses for high-acuity practice requires educational approaches that allow safe rehearsal of complex clinical situations, yet evidence from routine programme delivery remains mixed when immersive…

View details →DOI: 10.21203/rs.3.rs-9187827/v1
Negative / Null Result ReportMedicine

The Effect of Concomitant Hysterectomy Route on Robotic Sacrocolpopexy Outcomes.

Swallow C, Imamoglu M, Imamoglu AG et al. · 2025 · Urogynecology (Philadelphia, Pa.)

Importance Sacrocolpopexy is essential in the surgical management of advanced pelvic organ prolapse, and selecting the appropriate route for concomitant hysterectomy is critical. Objectives The aim of this study was to evaluate the effect…

View details →DOI: 10.1097/spv.0000000000001659
Negative / Null Result ReportOpen accessMedicine

Ductus Arteriosus Morphology in Pulmonary Atresia With Ventricular Septal Defect: A Retrospective Case Series Comparing Echocardiography and Digital Subtraction Angiography.

Quan TT, Nguyen HM, Nguyen HT et al. · 2026 · Cureus

Objective This study aims to describe ductus arteriosus (DA) morphology in patients with pulmonary atresia with ventricular septal defect (PA-VSD) and to assess exploratory paired differences between echocardiography and digital…

View details →DOI: 10.7759/cureus.108765
Negative / Null Result ReportMedicine

Embryo Euploidy Rates and Reproductive Outcomes Following Ethanol Sclerotherapy, Laparoscopic Cystectomy, or No Intervention for Ovarian Endometriomas Prior to IVF with PGT-A: A Retrospective Cohort Study.

Goc G, Sukur YE · 2026 · Journal of minimally invasive gynecology

Study objective To compare embryo euploidy rates and reproductive outcomes among women with ovarian endometriomas who underwent ethanol sclerotherapy (EST), laparoscopic cystectomy, or expectant management prior to in vitro fertilization…

View details →DOI: 10.1016/j.jmig.2026.06.010
Negative / Null Result ReportMedicine

Appendiceal location in Japanese children with acute appendicitis: pelvic predominance and diagnostic and operative implications.

Koga S, Noguchi S, Kondo T · 2026 · Pediatric surgery international

Purpose Appendiceal location may affect the diagnosis and surgical management of acute appendicitis. However, pediatric-specific data remain limited. This study evaluated appendiceal location in Japanese children with acute appendicitis…

View details →DOI: 10.1007/s00383-026-06498-0
Negative / Null Result Report

Impact of Postoperative Silodosin on Delayed Stone-Free Status After Retrograde Intrarenal Surgery: Emphasis on Patients with Residual Fragments

Akdag A, Aktas E, Kutlu A et al. · 2026 · Preprint

Abstract Purpose: Residual fragments after retrograde intrarenal surgery (RIRS) may compromise delayed stone-free (SF) status and increase the likelihood of secondary intervention. This study evaluated the association between postoperative…

View details →DOI: 10.21203/rs.3.rs-9849277/v1
Negative / Null Result ReportMedicine

First head-to-head comparison of allograft repair, direct neurorrhaphy and non-surgical management for iatrogenic trigeminal nerve injury: a prospective multicentre cohort study with doubly robust analysis.

Van der Cruyssen F, Willaert R, Palla B et al. · 2026 · International journal of oral and maxillofacial surgery

Trigeminal nerve injuries severely degrade quality of life, yet comparative effectiveness evidence for existing treatments is scarce. The authors prospectively followed 153 adults with iatrogenic lingual or inferior alveolar nerve injuries…

View details →DOI: 10.1016/j.ijom.2026.06.014
Negative / Null Result ReportMedicine

Relationship between aggregate index of systemic inflammation with miscarriage and pregnancy complications.

Baştemur AG, Haliloğlu E, Tanaçan A et al. · 2026 · Journal of reproductive immunology

Aim This study aimed to investigate the association between the aggregate index of systemic inflammation (AISI), a novel indicator of inflammation, miscarriage, and other pregnancy complications in patients with threatened miscarriage.…

View details →DOI: 10.1016/j.jri.2026.104869
Negative / Null Result Report

Impact of Preoperative Teriparatide Use on Proximal Junctional Kyphosis Prevention in Osteopenic/Osteoporotic Patients Undergoing Adult Spinal Deformity Surgery: A Propensity Score-Matched Study

Oh J, Park J, Kang D et al. · 2026 · Preprint

Background: /Objectives: Poor bone quality significantly increases the risk of mechanical complications after adult spinal deformity (ASD) surgery, including proximal junctional kyphosis (PJK) and proximal junctional failure (PJF).…

View details →DOI: 10.20944/preprints202606.1461.v1
Negative / Null Result ReportMedicine

Utility of the Frontal-Plane QRS-T Angle in a Real-World Screening Population, for Identification of Hypertrophic Cardiomyopathy.

Wayne KS, Liu H, Canales KK et al. · 2026 · Pediatric cardiology

The frontal QRS-T angle, derived from a standard 12-lead electrocardiogram (ECG), quantifies the relationship between ventricular depolarization and repolarization. Although a widened angle has been associated with myocardial disarray and…

View details →DOI: 10.1007/s00246-026-04329-6
Negative / Null Result ReportMedicine

Inflammatory biomarkers and sarcopenia in older adults.

Kanakan A, Singh A, Kumari S et al. · 2026 · Frontiers in aging

Chronic inflammation contributes to the pathogenesis of sarcopenia in older adults. This study aimed to evaluate the correlation between inflammatory biomarkers such as C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α),…

View details →DOI: 10.3389/fragi.2026.1770257
Negative / Null Result Report

Effects of Arabica and Chicory Coffee on Metabolic and Inflammatory Biomarker Responses to Acute Exercise: A Randomized Crossover Study

özcan FÖ, OKUDU C, Odabaş Hİ et al. · 2026 · Preprint

Abstract Purpose Chicory coffee is increasingly consumed as a caffeine-free alternative to traditional coffee; however, its acute effects during exercise remain unclear. This study aimed to compare the effects of a single serving of…

View details →DOI: 10.21203/rs.3.rs-9678223/v1