Negative / Null Result ReportMedicine
Tada A, Ihara S, Suwa J et al. · 2026 · Pediatrics international : official journal of the Japan Pediatric Society
Background Perioperative antimicrobial therapy is important to prevent central nervous system (CNS) infections following cerebrospinal fluid (CSF) shunt insertion, but the optimal duration remains unclear. This study aimed to evaluate the…
View details →DOI: 10.1111/ped.70372 Negative / Null Result ReportOpen accessMedicine
Shafiei SH, Latorre MR, Shimmin A · 2026 · Bone & joint open
Aims Restoring native hip biomechanics is essential for the long-term success of total hip arthroplasty (THA). Lateralized (offset) acetabular liners were developed to increase global offset and improve soft-tissue tension, but their…
View details →DOI: 10.1302/2633-1462.76.bjo-2026-0033.r1 Negative / Null Result ReportMedicine
Ptomey LT, Helsel BC, Montgomery RN et al. · 2026 · Medicine and science in sports and exercise
Purpose Individuals with Alzheimer's disease and related dementias (ADRD) and their caregivers often experience reduced physical activity (PA), diminished functional fitness, and heightened health risks. Remotely delivered PA interventions…
View details →DOI: 10.1249/mss.0000000000003974 Negative / Null Result ReportMedicine
Yang J, Lim J, Kim YJ et al. · 2026 · Journal of medical virology
Tenofovir alafenamide (TAF) exhibits antiviral efficacy comparable to tenofovir disoproxil fumarate (TDF). Nonetheless, concerns persist regarding TAF's impact on the lipid profile and potential atherosclerotic cardiovascular disease…
View details →DOI: 10.1002/jmv.70829 Negative / Null Result ReportMedicine
Kim SH, Quinn MA, Ananyev J et al. · 2026 · Medicine and science in sports and exercise
Introduction Childhood growth restriction can lead to lasting developmental changes, increasing susceptibility to chronic diseases and neurodegenerative conditions in adulthood. High-intensity interval training (HIIT) elevates…
View details →DOI: 10.1249/mss.0000000000003964 Negative / Null Result ReportMedicine
Sunderrajan A, Cursio J, Mason N et al. · 2026 · Journal of hospital medicine
Background Sleep is essential for recovery in hospitalized patients, yet frequent disruptions from medical care make rest difficult. Most prior efforts have focused on environmental modifications, often overlooking patients' role in…
View details →DOI: 10.1002/jhm.70273 Negative / Null Result Report
Curran-Alfaro CM, Side CM, Alluri A et al. · 2026 · Preprint
It is becoming increasingly clear that chronic exposure to lower levels of ethanol impact learning and behavior. To determine the impact of chronic low-dose ethanol exposure on sensitivity to changes in stimulus value, a conditioned taste…
View details →DOI: 10.64898/2026.06.08.730505 Negative / Null Result ReportOpen accessMedicine
Herzog DS, Jo J, Nakajima D et al. · 2026 · Translational animal science
Two experiments were conducted to determine the effect of ruminally protected lysine (AjiPro-L) supplementation on performance and nitrogen (N) balance of feedlot cattle fed decreasing concentrations of dietary protein. Diets contained (DM…
View details →DOI: 10.1093/tas/txag076 Negative / Null Result ReportMedicine
Medina Muñoz M, Gallego Campillo S, Martín Peinador Y et al. · 2026 · Indian pediatrics
Objective Lower respiratory tract infections (LRTIs) are a common cause of primary care visits in infants. This study was done to evaluate the course of LRTIs before-and-after the introduction of nirsevimab and to identify the associated…
View details →DOI: 10.1007/s13312-026-00385-6 Negative / Null Result ReportMedicine
Larsen MB, Faurschou IK, Haas S · 2026 · Techniques in coloproctology
Background The optimal treatment for complex Pilonidal Sinus Disease (PSD) is still debated. Despite great advances with the introduction of off-midline closure techniques, healing problems and recurrence remain challenges. We aimed to…
View details →DOI: 10.1007/s10151-026-03377-7 Negative / Null Result ReportMedicine
Tanaka R, Tokai S, Oi N et al. · 2026 · The Science of the total environment
Sap flow measured at basal trunk (Fd_base) has been used to estimate canopy transpiration and ozone uptake in forests. Although diurnal patterns of Fd_base do not always correspond to those of canopy transpiration, little is known about…
View details →DOI: 10.1016/j.scitotenv.2026.181975 Negative / Null Result ReportMedicine
Debunne N, De Letter K, Delanghe J et al. · 2026 · Clinical chemistry and laboratory medicine
Objectives Carbohydrate-deficient transferrin (CDT) is a specific biomarker for chronic excessive alcohol consumption. The IFCC Working Group on CDT Standardization recommends 2-sialo-transferrin (2-sialo-Tf) as the sole measurand, with a…
View details →DOI: 10.1515/cclm-2026-0346 Negative / Null Result ReportOpen accessMedicine
Wang Y, Li H, Chen Y et al. · 2026 · Global medical genetics
In patients with primary immune thrombocytopenia (ITP), the risk of thrombosis associated with thrombopoietin receptor agonists (TPO-RAs) remains debated. This study compared the thrombosis occurrence in ITP patients before and after the…
View details →DOI: 10.1016/j.gmg.2026.100107 Negative / Null Result ReportMedicine
Ruangsubvilai N, Au-Yeung K, Wongbuddha C et al. · 2026 · The American journal of cardiology
Limited data exist on outcomes for patients with mitral stenosis (MS) who have previously undergone percutaneous mitral commissurotomy (PMC) and later require surgical mitral valve replacement (MVR). This study evaluates the impact of…
View details →DOI: 10.1016/j.amjcard.2025.12.023 Negative / Null Result ReportMedicine
Furtado Fernandes L, Davis MT, Luo W et al. · 2026 · Personality disorders
Structured clinical interviews are the gold standard for identifying borderline personality disorder (BPD) in research. No self-report instrument has been validated as a replacement tool for BPD diagnosis. However, clinical interviews can…
View details →DOI: 10.1037/per0000771 Negative / Null Result ReportMedicine
Stokes DJ, Cram TR, Pasic N et al. · 2026 · The American journal of sports medicine
Background The "July effect" suggests increased patient morbidity and mortality during the early academic year due to new resident involvement. Evidence specific to orthopaedic sports medicine is limited. Purpose To evaluate the effect of…
View details →DOI: 10.1177/03635465261423216 Negative / Null Result ReportMedicine
Cantu-Martinez O, Greene SJ, Chinnakondepalli KM et al. · 2026 · Journal of cardiac failure
Background For patients with heart failure (HF), hyperkalemia (HK) may prevent optimal renin-angiotensin system inhibitor (RASi) use. Randomized trials show that patiromer, a contemporary potassium binder, reduces serum potassium (sK + )…
View details →DOI: 10.1016/j.cardfail.2026.03.025 Negative / Null Result ReportMedicine
Jensen GB, Olsen MH, Jensen MT et al. · 2026 · Danish medical journal
Introduction The CLARICOR randomised trial of clarithromycin versus placebo in patients with stable ischaemic heart disease found increased all-cause and cardiovascular mortality after a brief clarithromycin regimen, suggesting a possible…
View details →DOI: 10.61409/a08250630 Negative / Null Result ReportMedicine
Choi JY, Joo H, Kim JS et al. · 2026 · Public health
Objective In February 2024, over 90% of South Korea's resident physicians resigned in protest of government medical school expansion policies, creating an unprecedented healthcare crisis. This study examined whether this mass exodus…
View details →DOI: 10.1016/j.puhe.2026.106225 Negative / Null Result ReportMedicine
Pazos J, Fox DJ, Devi A et al. · 2026 · Food chemistry
Cabernet Sauvignon grapes were harvested at three different maturities (unripe, ripe, overripe, represented by Harvest 1, 2 and 3) and used for winemaking, adjusting total soluble solids of each harvest to three concentrations (∼11 %, 14…
View details →DOI: 10.1016/j.foodchem.2025.147714 Negative / Null Result ReportMedicine
Orbell SL, Lund BC, Kim N et al. · 2026 · Diabetes technology & therapeutics
The impacts of the rapid transition to telehealth care among Veterans on insulin pumps (VIPs) at the onset of the COVID-19 pandemic have not yet been studied. We performed a longitudinal analysis of VIP outcomes from October 1, 2018 to…
View details →DOI: 10.1177/15209156251403561 Negative / Null Result ReportMedicine
DeFrancesco CJ, Cavendish E, Kocher MS · 2026 · The American journal of sports medicine
Background Lateral extra-articular tenodesis (LET) can reduce the risk of graft failure after anterior cruciate ligament (ACL) reconstruction in adolescents and young adults. It is unclear whether the use of this procedure increases risks…
View details →DOI: 10.1177/03635465251393524 Negative / Null Result ReportMedicine
Lytchiér JVC, Okur MI, Rutkowski W et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Introduction Neoadjuvant immune checkpoint inhibitors (ICI) have recently entered clinical practice in management of melanoma, yet its impact on surgical outcomes remains unclear. This study evaluated the influence of neoadjuvant ICI on…
View details →DOI: 10.1016/j.ejso.2026.111403 Replication FailureMedicine
Josefsson ML, Uustal E, Sohlberg S et al. · 2026 · Acta obstetricia et gynecologica Scandinavica
Introduction Anal incontinence can have a significant negative impact on quality of life. The leading cause of anal incontinence among women of child-bearing age is obstetric-related perineal injury. The objective of this study was to…
View details →DOI: 10.1111/aogs.70124 Replication FailureMedicine
Batashvili M, Israel BH, Levy DA et al. · 2026 · International journal of psychophysiology : official journal of the International Organization of Psychophysiology
Tactile texture memory has been underexplored compared to visual and auditory memory, despite its importance in daily functioning. Prior research indicates that theta oscillations support memory consolidation across modalities, and frontal…
View details →DOI: 10.1016/j.ijpsycho.2025.113318 Replication Failure
Rain AZ, Sundararaghavan HG, Ji K · 2025 · Preprint
Midkine (MDK) is a heparin-binding growth factor that promotes tumor growth in many cancers and may contribute to type I neurofibromatosis (NF1) tumor by stimulating Schwann cell proliferation and supporting neurofibroma growth. Here, we…
View details →DOI: 10.1101/2025.10.20.683475 Negative / Null Result ReportOpen accessMedicine
Tonegawa-Kuji R, Kanaoka K, Takemoto S et al. · 2026 · Brazilian journal of cardiovascular surgery
Surgical left atrial appendage occlusion (S-LAAO) is increasingly performed during cardiac surgery, but perioperative outcomes remain uncertain. Using a nationwide Japanese inpatient database, we analyzed 25,059 adults undergoing valve or…
View details →DOI: 10.21470/1678-9741-2025-0299 Negative / Null Result ReportMedicine
Gong W, Chen X, Zhao W et al. · 2026 · Sleep medicine
Background Obstructive sleep apnea (OSA) and age are strongly associated with recurrent events following acute coronary syndrome (ACS), but their interaction is unclear. This study was designed to evaluate the age-dependent impact of OSA…
View details →DOI: 10.1016/j.sleep.2026.108829 Negative / Null Result ReportMedicine
Wong ES, Taylor LL, Rojas J et al. · 2026 · Healthcare (Amsterdam, Netherlands)
Background In the Veterans Health Administration (VHA), primary care is delivered through a team-based medical home called the Patient Aligned Care Team (PACT). Increasing team panel size is one approach to addressing staffing challenges…
View details →DOI: 10.1016/j.hjdsi.2026.100778 Negative / Null Result ReportMedicine
Soares EMKVK, da Cruz CJG, Ives SJ et al. · 2026 · Nutrients
Objectives : To determine whether caffeine supplementation and its expectancy influence muscle strength (ST) and muscle endurance (ME) using a balanced-placebo design. Methods: Using a randomized, double-blind, balanced-placebo design,…
View details →DOI: 10.3390/nu18050801