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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21216 results · page 47 of 708

Negative / Null Result ReportOpen accessBusiness, Management and Accounting

Determinants of the Dividend Policy: An Empirical Study on the Lebanese Listed Banks

Christopher Maldajian, Rim El Khoury · 2014 · International Journal of Economics and Finance

This research aims at investigating the factors determining the dividend payout policy in the Lebanese banks listed on the Beirut Stock Exchange. This study considers the impact of seven variables, namely, profitability, liquidity, leverage, firm size, growth, firm risk and previous year’s dividend payout on the dividend payout ratios by using an unbalanced panel dataset of listed banks between the years of 2005 and 2011. Two models were tested using the OLS and the dynamic panel regressions. Empirical results show that the dividend payout policies are positively affected by the firm size, ris

View details →DOI: 10.5539/ijef.v6n4p240Cited by 115
Negative / Null Result ReportOpen accessNursing

Evaluating the pathways from small-scale irrigation to dietary diversity: evidence from Ethiopia and Tanzania

Simone Passarelli, Dawit Mekonnen, Elizabeth Bryan et al. · 2018 · Food Security

Interventions that aim to increase water availability for agriculture hold great potential for improving nutrition through increasing food production, generating income, enhancing water access and sanitation and hygiene conditions, and through strengthening women’s empowerment. Yet there is scarce evidence on the linkages between small-scale irrigation and the pathways through which nutrition outcomes can be achieved. Using data from a cross-sectional household survey collected in Ethiopia and Tanzania, we explored the potential for small-scale irrigation to contribute to improved diets, and i

View details →DOI: 10.1007/s12571-018-0812-5Cited by 115
Negative / Null Result ReportOpen accessBusiness, Management and Accounting

PENGETAHUAN INVESTASI, MOTIVASI INVESTASI, LITERASI KEUANGAN DAN LINGKUNGAN KELUARGA PENGARUHNYA TERHADAP MINAT INVESTASI DI PASAR MODAL

Akhmad Darmawan, Kesih Kurnia, Sri Rejeki · 2019 · Jurnal Ilmiah Akuntansi dan Keuangan

This study aims to analyze the effect of investment knowledge, investment motivation, financial literacy and family environment on the interest in investing in the capital market. This type of research is quantitative. The population of this study were students of the Management Study Program of the Faculty of Economics and Business, Muhammadiyah Purwokerto University in the year 2016 and 2017 with the sample criteria of active students of FEB UMP and those who were / had taken financial management and entrepreneurship courses. Data collection in this study using the questionnaire method. Inst

View details →DOI: 10.32639/jiak.v8i2.297Cited by 114
Negative / Null Result ReportOpen accessBusiness, Management and Accounting

Persistence of Integration in the Face of Specialization: How Firms Navigated the Winds of Disintegration and Shaped the Architecture of the Semiconductor Industry

Rahul Kapoor · 2013 · Organization Science

Although the stylized model of industry evolution suggests that firms transform from vertical integration to specialization over time, many industries still exhibit a continued persistence of integrated firms. In exploring this puzzle, I…

View details →DOI: 10.1287/orsc.1120.0802Cited by 114
Negative / Null Result ReportOpen accessMedicine

Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide

Michael Wahl, Joanna J. Phillips, Annette M. Molinaro et al. · 2016 · Neuro-Oncology

Background: Optimal adjuvant management of adult low-grade gliomas is controversial. Recently described tumor classification based on molecular subtype has the potential to individualize adjuvant therapy but has not yet been evaluated as…

View details →DOI: 10.1093/neuonc/now176Cited by 114
Negative / Null Result ReportPsychology

Attachment-related avoidance and the social and agentic content of nostalgic memories

Andrew A. Abeyta, Clay Routledge, Christina Roylance et al. · 2014 · Journal of Social and Personal Relationships

The reported research tested whether the social and agentic content of nostalgic memories varies as a function of attachment-related avoidance. We measured individual differences in attachment-related avoidance and anxiety and coded the…

View details →DOI: 10.1177/0265407514533770Cited by 114
Negative / Null Result ReportOpen accessBusiness, Management and Accounting

The impact of contextual factors on the efficacy of ISO 9000 adoption

Chris K.Y. Lo, Frank Wiengarten, Paul Humphreys et al. · 2013 · Journal of Operations Management

Abstract This study investigates the importance of contextual factors on the efficacy of ISO 9000 adoption. We explore the role of various contextual factors at the firm‐level (i.e., technology intensity, labor productivity, and labor…

View details →DOI: 10.1016/j.jom.2013.04.002Cited by 114
Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology

Comparison of 2 Blood Culture Media Shows Significant Differences in Bacterial Recovery for Patients on Antimicrobial Therapy

Rebecca Zadroga, David N. Williams, Richard L. Gottschall et al. · 2012 · Clinical Infectious Diseases

BACKGROUND: Antimicrobial removal devices in blood culture media are designed to remove antibiotics from the blood culture solution, thereby facilitating bacterial growth. How well these devices function clinically has not been…

View details →DOI: 10.1093/cid/cis1021Cited by 114
Negative / Null Result ReportOpen accessMedicine

Clinical outcome of children and adults with localized Ewing sarcoma

Abha A. Gupta, Alberto S. Pappo, Natasha Saunders et al. · 2010 · Cancer

BACKGROUND: As Ewing sarcoma (EWS) can affect children and adults, these patients can be treated at either a pediatric or an adult institution. This study investigated whether differences in therapeutic strategy undertaken in pediatric and…

View details →DOI: 10.1002/cncr.25144Cited by 114
Negative / Null Result ReportOpen accessMedicine

A randomized placebo‐controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis

Merit Cudkowicz, Stacy Lindborg, Namita Goyal et al. · 2021 · Muscle & Nerve

INTRODUCTION/AIMS: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative illness with great unmet patient need. We aimed to evaluate whether mesenchymal stem cells induced to secrete high levels of neurotrophic factors…

View details →DOI: 10.1002/mus.27472Cited by 114
Negative / Null Result ReportOpen accessMedicine

Predictors of outcome in paediatric IgA nephropathy with regard to clinical and histopathological variables (Oxford classification)

Stella Edström Halling, Magnus Söderberg, U. Berg · 2011 · Nephrology Dialysis Transplantation

BACKGROUND: There has been a lack of international consensus on the classification and the predictive value of the histopathology findings in IgA nephropathy (IgAN). Recently, the International IgA Nephropathy Network has developed the…

View details →DOI: 10.1093/ndt/gfr339Cited by 114
Negative / Null Result ReportOpen accessMedicine

A prospective study of time to healing and hypertrophic scarring in paediatric burns: every day counts

Elizabeth Chipp, Lisa Charles, Clare Thomas et al. · 2017 · Burns & Trauma

BACKGROUND: It is commonly accepted that burns taking longer than 3 weeks to heal have a much higher rate of hypertrophic scarring than those which heal more quickly. However, some of our patients develop hypertrophic scars despite healing…

View details →DOI: 10.1186/s41038-016-0068-2Cited by 114
Negative / Null Result ReportOpen accessMedicine

Gastrointestinal Bleeding in Patients With Coronavirus Disease 2019: A Matched Case-Control Study

Tracey A. Martin, David Wan, Kaveh Hajifathalian et al. · 2020 · The American Journal of Gastroenterology

INTRODUCTION: Although current literature has addressed gastrointestinal presentations including nausea, vomiting, diarrhea, abnormal liver chemistries, and hyperlipasemia as possible coronavirus disease 2019 (COVID-19) manifestations, the…

View details →DOI: 10.14309/ajg.0000000000000805Cited by 114
Negative / Null Result ReportOpen accessMedicine

Efficacy of the Enquiring About Tolerance (EAT) study among infants at high risk of developing food allergy

Michael R. Perkin, Kirsty Logan, Henry T. Bahnson et al. · 2019 · Journal of Allergy and Clinical Immunology

BACKGROUND: The Enquiring About Tolerance (EAT) study was a randomized trial of the early introduction of allergenic solids into the infant diet from 3 months of age. The intervention effect did not reach statistical significance in the intention-to-treat analysis of the primary outcome. OBJECTIVE: We sought to determine whether infants at high risk of developing a food allergy benefited from early introduction. METHODS: A secondary intention-to-treat analysis was performed of 3 groups: nonwhite infants; infants with visible eczema at enrollment, with severity determined by SCORAD; and infants

View details →DOI: 10.1016/j.jaci.2019.06.045Cited by 114
Negative / Null Result ReportOpen accessMedicine

Acute Kidney Injury in COVID-19 Patients: An Inner City Hospital Experience and Policy Implications

Umar Zahid, Preethi Ramachandran, Samuel Spitalewitz et al. · 2020 · American Journal of Nephrology

BACKGROUND: Although diffuse alveolar damage and respiratory failure are the key features of coronavirus disease 2019 (COVID-19), the involvement of other organs such as the kidney has also been reported. The reports of the incidence of…

View details →DOI: 10.1159/000511160Cited by 113
Negative / Null Result ReportOpen accessMedicine

Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study

Dilip R. Karnad, Rakesh Bhadade, Pradeep Kumar Verma et al. · 2014 · Intensive Care Medicine

PURPOSE: Ulinastatin, a serine protease inhibitor, inhibits several pro-inflammatory proteases and decreases inflammatory cytokine levels and mortality in experimental sepsis. We studied the effect of ulinastatin on 28-day all-cause…

View details →DOI: 10.1007/s00134-014-3278-8Cited by 113
Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology

Comparison of Diet versus Exercise on Metabolic Function and Gut Microbiota in Obese Rats

Rebecca J. Welly, Tzu‐Wen Liu, Terese M. Zidon et al. · 2016 · Medicine & Science in Sports & Exercise

UNLABELLED: Cardiometabolic impairments that begin early in life are particularly critical, because they often predict metabolic dysfunction in adulthood. Obesity, high-fat diet (HFD), and inactivity are all associated with adipose tissue…

View details →DOI: 10.1249/mss.0000000000000964Cited by 113
Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology

Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

Guillem Pascual‐Pasto, Miriam Bazán‐Peregrino, Nagore G. Olaciregui et al. · 2019 · Science Translational Medicine

VCN-01 is an oncolytic adenovirus designed to replicate selectively in tumor cells with high abundance of free E2F-1, a consequence of a dysfunctional RB1 pathway. Thus, we reasoned that VCN-01 could provide targeted therapeutic activity…

View details →DOI: 10.1126/scitranslmed.aat9321Cited by 113
Negative / Null Result ReportOpen accessSocial Sciences

A Local Dimension of Integration Policies? A Comparative Study of Berlin, Malmö, and Rotterdam

Rianne Dekker, Henrik Emilsson, Bernhard Krieger et al. · 2015 · International Migration Review

This study examines three theses on local integration policies by a qualitative comparative case study of integration policies in three cities in three different countries (Berlin, Malmö, and Rotterdam). We found little evidence of a…

View details →DOI: 10.1111/imre.12133Cited by 113
Negative / Null Result Report

Nonparametric expression analysis using inferential replicate counts

Anqi Zhu, Avi Srivastava, Joseph G Ibrahim et al. · 2019 · Nucleic Acids Research

Abstract A primary challenge in the analysis of RNA-seq data is to identify differentially expressed genes or transcripts while controlling for technical biases. Ideally, a statistical testing procedure should incorporate the inherent…

View details →DOI: 10.1093/nar/gkz622Cited by 112
Negative / Null Result ReportMedicine

Phase 3, randomized, placebo‐controlled study of zibotentan (ZD4054) in patients with castration‐resistant prostate cancer metastatic to bone

Joel B. Nelson, Karim Fizazi, Kurt Miller et al. · 2012 · Cancer

BACKGROUND: Endothelin-1 and the endothelin A (ET(A) ) receptor have been implicated in prostate cancer progression in bone. This study aimed to determine whether the specific ET(A) receptor antagonist, zibotentan, prolonged overall…

View details →DOI: 10.1002/cncr.27674Cited by 112
Negative / Null Result ReportNeuroscience

Case-Control Analysis of Cochlear Implant Performance in Elderly Patients

David R. Friedland, Christina L. Runge, Humera F. Baig et al. · 2010 · Archives of Otolaryngology - Head and Neck Surgery

OBJECTIVE: To characterize speech perception performance in elderly cochlear implant users compared with younger adult users. DESIGN: Case-control retrospective analysis from January 1, 1999, to January 28, 2008. SETTING: Tertiary care,…

View details →DOI: 10.1001/archoto.2010.57Cited by 112
Negative / Null Result ReportOpen accessMedicine

Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)

Sarah E. Boston, Xiaomin Lu, William T. N. Culp et al. · 2014 · Journal of the American Veterinary Medical Association

OBJECTIVE: To determine prognostic factors for and compare outcome among dogs with oral malignant melanoma following excision with or without various systemic adjuvant therapies. DESIGN: Retrospective case series. ANIMALS: 151 dogs with…

View details →DOI: 10.2460/javma.245.4.401Cited by 112
Negative / Null Result ReportOpen accessMedicine

Hepatic ratio of phosphatidylcholine to phosphatidylethanolamine predicts survival after partial hepatectomy in mice

Ling Ji, Todd Chaba, Lin-Fu Zhu et al. · 2011 · Hepatology

UNLABELLED: A major predictor of failed liver resection and transplantation is nonalcoholic fatty liver disease (NAFLD). NAFLD is linked to a wide spectrum of diseases including obesity and diabetes that are increasingly prevalent in…

View details →DOI: 10.1002/hep.24782Cited by 112
Negative / Null Result ReportOpen accessMedicine

Adjuvant chemotherapy in rectal cancer: Defining subgroups who may benefit after neoadjuvant chemoradiation and resection: A pooled analysis of 3,313 patients

Monique Maas, Patty J. Nelemans, Vincenzo Valentini et al. · 2014 · International Journal of Cancer

Recent literature suggests that the benefit of adjuvant chemotherapy (aCT) for rectal cancer patients might depend on the response to neoadjuvant chemoradiation (CRT). Aim was to evaluate whether the effect of aCT in rectal cancer is…

View details →DOI: 10.1002/ijc.29355Cited by 112
Negative / Null Result ReportEnvironmental Science

Diversity and stability of herbivorous fishes on coral reefs

L Thibaut, Sean R. Connolly, Hugh Sweatman · 2011 · Ecology

Biodiversity may provide insurance against ecosystem collapse by stabilizing assemblages that perform particular ecological functions (the "portfolio effect"). However, the extent to which this occurs in nature and the importance of…

View details →DOI: 10.1890/11-1753.1Cited by 112
Negative / Null Result ReportOpen accessMedicine

Association of Sex Hormones, Aging, and Atrial Fibrillation in Men

Jared W. Magnani, Carlee Moser, Joanne M. Murabito et al. · 2014 · Circulation Arrhythmia and Electrophysiology

BACKGROUND: Endogenous sex hormones have been related to cardiovascular outcomes and mortality. We hypothesized that sex hormones are related to atrial fibrillation (AF) in a community-based cohort of middle-aged to older men. METHODS AND…

View details →DOI: 10.1161/circep.113.001322Cited by 112
Negative / Null Result ReportNeuroscience

Childhood maltreatment, the corticotropin‐releasing hormone receptor gene and adult depression in the general population

Hans J. Grabe, Christian Schwahn, Katja Appel et al. · 2010 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics

Dysregulations of the hypothalamic-pituitary-adrenal (HPA) axis have been implicated in the pathogenesis of depressive disorders and the corticotropin-releasing hormone (CRH) was found to modulate emotional memory consolidation. Recently,…

View details →DOI: 10.1002/ajmg.b.31131Cited by 112
Negative / Null Result ReportBusiness, Management and Accounting

Factors affecting dividend policy in manufacturing companies in Indonesia Stock Exchange

Eko Wahjudi · 2019 · Journal of Management Development

Purpose The purpose of this paper is to analyze the variables that significantly affect dividend policy. Design/methodology/approach This research uses a type of comparative causal research (causal-comparative research), where the fact or…

View details →DOI: 10.1108/jmd-07-2018-0211Cited by 111