Negative / Null Result ReportOpen accessMedicine· cited by 114

Efficacy of the Enquiring About Tolerance (EAT) study among infants at high risk of developing food allergy

Michael R. Perkin; Kirsty Logan; Henry T. Bahnson; Tom Marrs; Suzana Radulović; Joanna Craven; Carsten Flohr; E. N. Clare Mills · 2019 · Journal of Allergy and Clinical Immunology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

The finding, in one line

“The intervention effect did not reach statistical significance in the intention-to-treat analysis of the primary outcome.”

Abstract

BACKGROUND: The Enquiring About Tolerance (EAT) study was a randomized trial of the early introduction of allergenic solids into the infant diet from 3 months of age. The intervention effect did not reach statistical significance in the intention-to-treat analysis of the primary outcome. OBJECTIVE: We sought to determine whether infants at high risk of developing a food allergy benefited from early introduction. METHODS: A secondary intention-to-treat analysis was performed of 3 groups: nonwhite infants; infants with visible eczema at enrollment, with severity determined by SCORAD; and infants

Abstract by Michael R. Perkin; Kirsty Logan; Henry T. Bahnson; Tom Marrs; Suzana Radulović; Joanna Craven; Carsten Flohr; E. N. Clare Mills, Journal of Allergy and Clinical Immunology (2019) — licensed CC BY 4.0.

Read the full paper (open access)