A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21322 results · page 452 of 711
Milinski L, Nodal FR, King AJ et al. · 2026 · Preprint
Subjective tinnitus is the most common auditory phantom perception in the absence of an acoustic stimulus yet there is no cure nor widely effective treatment to date. Previously, we suggested that sleep may contribute to tinnitus…
Costa E, Vercoutere A, Alexander S et al. · 2026 · Preprint
Introduction During the COVID-19 pandemic, gestational diabetes mellitus (GDM) prevalence showed variable changes across regions, with most reporting increases and others decreases; anxiety and lifestyle modifications linked to…
Shen R, Yu Y, Ma Y et al. · 2026 · Biomolecules
Gatifloxacin (GTFX), a fourth-generation fluoroquinolone, causes metabolic disturbances in mammals, but its hepatotoxic mechanisms in aquatic vertebrates remain unclear. This study investigated whether GTFX induces liver injury in…
Yıldırım Erdal BD, Bayraktar S · 2026 · Turkish journal of ophthalmology
Objectives To investigate the effects of selective laser trabeculoplasty (SLT) on the iridocorneal angle, anterior chamber, and iris in patients with pseudoexfoliation glaucoma (PEXG) and to evaluate the relationship between these…
Streese L, Ritter ET, Schoch R et al. · 2026 · Journal of vascular research
Purpose We aimed to investigate the effect of different exercise modes on retinal microvascular endothelial function in patients with HF with preserved ejection fraction (HFpEF). Methods Twenty-eight patients were randomly allocated to…
Kumar D S, Dandekar S, Prakash GH · 2026 · BMC medical education
Background Antimicrobial resistance is a major global public health threat, necessitating improved antibiotic stewardship. India's Competency-Based Medical Education (CBME) framework requires robust methods to assess and cultivate clinical…
Hornemann A, Bosserhoff M, Coltan L et al. · 2026 · International urogynecology journal
Introduction and hypothesis This study investigates the postoperative mobility following partial semitendinosus tendon harvesting performed during pelvic organ prolapse (POP) repair using the Hornemann Tendon Transplantation (HoTT®)…
Sethi D, Prajapati S, Garg G · 2026 · Anesthesia and pain medicine
Background A few studies investigating the perioperative use of lung ultrasound (LUS) have shown loss of lung aeration with decline in diaphragmatic function after general anesthesia. We aimed to measure changes in lung aeration and…
Kume D, Horiuchi M, Nishiwaki M · 2026 · Microvascular research
Acute mental stress (MS) can impair macrovascular function, causing increased arterial stiffness and endothelial dysfunction; however, its effect on microvascular function remains largely unclear. This study examined the impact of acute MS…
Oliver CJ, Del Vecchio L, Climstein M et al. · 2026 · Clinical nutrition ESPEN
Background Accurate assessment of body composition beyond BMI is necessary in clinical care. Bioelectrical impedance analysis (BIA) and 3D scanning (3DS) are practical two-compartment (2C) methods estimating % body fat (%BF), fat mass…
Baytaroğlu HN, Yalçınsoy KÖ · 2026 · Preprint
Abstract Purpose To evaluate the effect of topical cyclosporine-A treatment on edematous punctal stenosis (PS) using anterior segment optical coherence tomography (AS-OCT). Methods Patients with edematous PS who suffered from epiphora for…
Kwaiser MM, King JF, Troyer LE et al. · 2026 · Preprint
Abstract Background Many physical activity interventions exist, but few are sustained, with additional barriers in rural populations. The primary objective was to evaluate the feasibility of a refined implementation strategy for a…
Diego-Navarro O, Copete S, Moreno-Martínez A et al. · 2026 · European journal of ophthalmology
PurposeTo evaluate functional and anatomical outcomes after intravitreal dexamethasone implant (DEXI) in macular edema secondary to retinal vein occlusion (ME-RVO), comparing treatment-naïve eyes with early-switch (ES) and late-switch (LS)…
Şafak A, Karakaya E, Yıldırım S et al. · 2026 · Transplantation proceedings
Introduction Although liver biopsy in patients with acute cellular rejection (ACR) is the gold standard for diagnosis, its invasive nature highlights the need for reliable noninvasive biomarkers. With evidence suggesting that peripheral…
Parapiboon W, Pattanapongpaibool A, Sanprasert S · 2026 · International urology and nephrology
Purpose The benefits of incremental peritoneal dialysis (IPD) with days off remain controversial. This study aimed to compare the survival rate between IPD with days off and standard-dose peritoneal dialysis (PD). Methods Participants who…
Musbahi O, Pouris K, Hadjixenophontos S et al. · 2025 · World journal of methodology
Background Relieving pain is central to the early management of knee osteoarthritis, with a plethora of pharmacological agents licensed for this purpose. Intra-articular corticosteroid injections are a widely used option, albeit with…
Bushaibah O · 2026 · Environmental monitoring and assessment
Understanding long-term microbial dynamics in semi-enclosed coastal systems is essential for evaluating wastewater-related impacts and informing management responses. This study applies an integrated nonparametric diagnostic framework to…
Alatrash M, Moustafa MS, Nashed GA et al. · 2026 · Preprint
Background: The gallbladder plays an essential role in lipid homeostasis through bile storage and regulated release. Gallstone disease is frequently associated with dyslipidemia, and cholecystectomy is one of the most common abdominal…
Torres K, Terzi S, Simón L · 2026 · Scientific reports
Healthier diets are associated with fewer mental health symptoms, whereas higher consumption of ultra-processed foods is associated with psychological distress. This pilot study aimed to evaluate the impact of a nutrition education…
Aytekin AM, Ulusoy HE, Efe MA et al. · 2026 · The journal of obstetrics and gynaecology research
Objective To evaluate the impact of bilateral salpingectomy added to hysterectomy performed via different surgical routes on ovarian reserve, ovarian stromal blood flow, and sexual function in premenopausal women. Methods This prospective…
Lee YJ, Clement ND, Asopa V et al. · 2026 · The Journal of arthroplasty
Background The objectives were to evaluate whether the EQ-5D-3L questionnaire demonstrated a ceiling effect after total hip arthroplasty (THA), identify which patients were more likely to reach the ceiling score, and determine whether this…
Bowman J, Cornelius JM, Schoen A et al. · 2026 · Journal of experimental zoology. Part A, Ecological and integrative physiology
The release of waterborne chemical cues is a well-documented anti-predator strategy in teleost fish, allowing individuals to detect, and respond to, predation threats. However, little is known about whether an ancient group of fishes,…
Balachandran A, Elliot JLN, Curtis S et al. · 2026 · Preprint
Abstract Background: Adolescents and young adults (AYAs) with congenital heart disease (CHD) are frequently lost to follow-up during transition to adult congenital heart disease (ACHD) care. Successful transition requires navigating…
Kikuchi M, Yoshimura Y, Tanaka S et al. · 2026 · Preprint
Abstract Facilitated drum circles may promote social bonding in children, yet endocrine responses vary widely. In a school-based pilot study (n = 11; aged 9–10 years), we examined whether the temporal structure of facilitator–child…
Booth SE, Rubins D, O'Donoghue AL et al. · 2026 · Applied clinical informatics
Intravenous (IV) and oral (PO) acetaminophen have equivalent bioavailability and effectiveness, but IV formulations are significantly more expensive. Clinical decision support (CDS) tools can encourage cost-effective prescribing. We…
Seijas R, Vázquez M, Barastegui D et al. · 2026 · International orthopaedics
Purpose To characterise recovery trajectories across nine patient-reported outcomes (PROs) during the first twelve months after hip arthroscopy for femoroacetabular impingement syndrome (FAIS), and to determine whether six-month assessment…
Aftabi S, Leslie WD · 2026 · Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
Dual-energy X-ray absorptiometry (DXA) is the gold standard for assessing bone mineral density (BMD), but technical factors such as acquisition mode may affect measurement. On GE Healthcare DXA systems, Thin and Thick modes are often…
Singh PK, Kumar BS, Nandi S et al. · 2026 · Veterinary medicine international
Bisphenol A (BPA), an organic environment chemical, has extensive presence in consumer goods and food/feed items. The present study aimed to explore how BPA influenced the viability, proliferation, apoptosis, and steroidogenic activity of…
Lin YH, Teng MMH · 2026 · PloS one
Monitoring bone mineral density (BMD) changes can be challenging when both the spine and hips are included in follow-up assessments. This study aimed to evaluate BMD changes using different monitoring approaches, including comparisons…
Abd Elghany AA, Kamel Eyada MM, Maher SA et al. · 2026 · Cytokine
Background Alopecia areata (AA) is a common autoimmune disease which causes non-scarring patches of hair loss and has a 2% lifetime risk. Its chronic, recurrent nature makes treatment difficult. Potential roles of the JAK/STAT pathway,…